MX2020002287A - Metodo de produccion para polisulfato de pentosan. - Google Patents
Metodo de produccion para polisulfato de pentosan.Info
- Publication number
- MX2020002287A MX2020002287A MX2020002287A MX2020002287A MX2020002287A MX 2020002287 A MX2020002287 A MX 2020002287A MX 2020002287 A MX2020002287 A MX 2020002287A MX 2020002287 A MX2020002287 A MX 2020002287A MX 2020002287 A MX2020002287 A MX 2020002287A
- Authority
- MX
- Mexico
- Prior art keywords
- production method
- pentosan polysulfate
- acidic xylooligosaccharide
- plant
- obtaining
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
- C08B37/0024—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid beta-D-Glucans; (beta-1,3)-D-Glucans, e.g. paramylon, coriolan, sclerotan, pachyman, callose, scleroglucan, schizophyllan, laminaran, lentinan or curdlan; (beta-1,6)-D-Glucans, e.g. pustulan; (beta-1,4)-D-Glucans; (beta-1,3)(beta-1,4)-D-Glucans, e.g. lichenan; Derivatives thereof
- C08B37/0027—2-Acetamido-2-deoxy-beta-glucans; Derivatives thereof
- C08B37/003—Chitin, i.e. 2-acetamido-2-deoxy-(beta-1,4)-D-glucan or N-acetyl-beta-1,4-D-glucosamine; Chitosan, i.e. deacetylated product of chitin or (beta-1,4)-D-glucosamine; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
- C08B37/0057—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid beta-D-Xylans, i.e. xylosaccharide, e.g. arabinoxylan, arabinofuronan, pentosans; (beta-1,3)(beta-1,4)-D-Xylans, e.g. rhodymenans; Hemicellulose; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/0003—General processes for their isolation or fractionation, e.g. purification or extraction from biomass
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Materials Engineering (AREA)
- Polymers & Plastics (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Diabetes (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Sustainable Development (AREA)
- Epidemiology (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Cosmetics (AREA)
Abstract
La presente invención proporciona un método para producir polisulfato de pentosán, incluyendo el método un primer paso de obtener un xilooligosacárido ácido de una materia prima derivada de plantas y un segundo paso de obtener polisulfato de pentosán del xilooligosacárido ácido. El primer paso incluye un paso de despolimerizar la materia prima derivada de plantas. El segundo paso incluye un paso de sulfatar el xilooligosacárido ácido. El método incluye además un paso de desacetilación en el que se agrega una base para alcanzar un pH de 11 o mayor. El paso de desacetilación es un paso efectuado después del paso de despolimerización. El método de producción de la presente invención puede proporcionar polisulfato de pentosán que tiene un bajo contenido de grupo acetilo y también produce de manera barata y eficiente polisulfato de pentosán con un alto rendimiento.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2016169710 | 2016-08-31 | ||
JP2017035917 | 2017-02-28 | ||
PCT/JP2017/031434 WO2018043668A1 (ja) | 2016-08-31 | 2017-08-31 | ポリ硫酸ペントサンの製造方法 |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2020002287A true MX2020002287A (es) | 2020-07-14 |
Family
ID=61305336
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2020002287A MX2020002287A (es) | 2016-08-31 | 2017-08-31 | Metodo de produccion para polisulfato de pentosan. |
Country Status (11)
Country | Link |
---|---|
US (1) | US11312790B2 (es) |
EP (1) | EP3677599A4 (es) |
JP (2) | JP6225321B1 (es) |
KR (1) | KR102591794B1 (es) |
CN (1) | CN111065654B (es) |
AU (1) | AU2017321818B2 (es) |
BR (1) | BR112020003899B1 (es) |
CA (1) | CA3074419C (es) |
MX (1) | MX2020002287A (es) |
SG (1) | SG11202001822WA (es) |
WO (1) | WO2018043668A1 (es) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU2017321817B2 (en) | 2016-08-31 | 2022-12-15 | Oji Holdings Corporation | Production method for acidic xylooligosaccharide, and acidic xylooligosaccharide |
JP6225321B1 (ja) | 2016-08-31 | 2017-11-08 | 王子ホールディングス株式会社 | ポリ硫酸ペントサンの製造方法 |
JP6281659B1 (ja) * | 2017-02-28 | 2018-02-21 | 王子ホールディングス株式会社 | ポリ硫酸ペントサン、医薬組成物及び抗凝固剤 |
SG11201911318SA (en) | 2017-05-31 | 2020-01-30 | Oji Holdings Corp | Moisturizing topical preparation |
WO2019054344A1 (ja) | 2017-09-12 | 2019-03-21 | 王子ホールディングス株式会社 | ポリ硫酸ペントサン及びポリ硫酸ペントサンの製造方法 |
CN111511773B (zh) * | 2017-12-20 | 2023-01-13 | 王子控股株式会社 | 戊聚糖多硫酸酯以及含有戊聚糖多硫酸酯的药物 |
EP3842048A4 (en) * | 2018-08-20 | 2022-03-30 | ReqMed Company, Ltd. | NOVEL PENTOSAN POLYSULFATE PREPARATION |
Family Cites Families (56)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS4843100B1 (es) | 1969-09-05 | 1973-12-17 | ||
JPS4843100A (es) | 1971-09-30 | 1973-06-22 | ||
US4168742A (en) | 1978-03-27 | 1979-09-25 | Hudson Products Corporation | Tube bundle |
FR2538404B1 (es) | 1982-12-28 | 1985-08-23 | Anic Spa | |
FR2543145B1 (fr) | 1983-03-24 | 1986-10-17 | Sanofi Sa | Nouveaux sulfates de xylanes, leur procede de preparation et leur activite anti-thrombotique et hypolipemiante |
JPS60112708A (ja) | 1983-11-24 | 1985-06-19 | Maruho Kk | 皮膚用保湿剤 |
FR2572731B1 (fr) | 1984-11-07 | 1987-03-06 | Sanofi Sa | Nouveaux sulfates de xylanes de bas poids moleculaires, leur procede de preparation et leur activite antithrombotique et hypolipemiante par voie orale |
JPS61130302A (ja) | 1984-11-30 | 1986-06-18 | Tokyo Univ | 抗凝血活性を有する硫酸化リボフラナン及びその製造法 |
JPS61130301A (ja) | 1984-11-30 | 1986-06-18 | Tokyo Univ | 抗凝血活性を有する硫酸化キシロフラナン及びその製造法 |
US5672334A (en) | 1991-01-16 | 1997-09-30 | Access Pharmaceuticals, Inc. | Invivo agents comprising cationic metal chelators with acidic saccharides and glycosaminoglycans |
FR2645745B1 (fr) | 1989-04-12 | 1991-09-27 | Anben Ste Civile | Compositions therapeutiques pour le traitement ou la prevention du ronflement |
DE3917982A1 (de) | 1989-06-02 | 1990-12-06 | Behringwerke Ag | Verwendung von xylanpolyhydrogensulfaten zur therapie von zellproliferations-bedingten erkrankungen |
FR2648463B1 (fr) | 1989-06-14 | 1993-01-22 | Inst Fs Rech Expl Mer | Polysaccharides sulfates, agent anticoagulant et agent anticomplementaire obtenus a partir de fucanes d'algues brunes et leur procede d'obtention |
JPH0776175B2 (ja) | 1990-04-26 | 1995-08-16 | サイトアーレクス・コーポレーシヨン | 損傷されたかまたは病気になった組織の局所的処置用の組成物および方法 |
US20010005720A1 (en) | 1995-06-07 | 2001-06-28 | U.S.A. As Represented By The Secretary Department Of Health And Human Services | Method of treating chronic progressive vascular scarring diseases |
DE19632840A1 (de) | 1996-08-14 | 1998-02-19 | Landsberger Albert | Vitamin A-haltige Zusammensetzung |
JPH10195107A (ja) | 1997-01-10 | 1998-07-28 | Shiseido Co Ltd | オリゴ硫酸化ヒアルロン酸 |
JP4336905B2 (ja) | 1997-12-19 | 2009-09-30 | マルホ株式会社 | 硫酸化多糖類含有皮膚保湿乳剤性ローション剤 |
US6593310B1 (en) | 2000-11-21 | 2003-07-15 | Arthropharm Pty. Ltd. | Treatment of osteoporosis |
DE10141106A1 (de) | 2001-08-22 | 2003-03-13 | Aventis Pharma Gmbh | Verwendung von Heparinoid-Derivaten zur Behandlung und Diagnose von mit Heparinoiden behandelbaren Erkrankungen |
JP4073661B2 (ja) | 2001-12-20 | 2008-04-09 | 王子製紙株式会社 | 酸性キシロオリゴ糖組成物の製造方法 |
JP3772749B2 (ja) | 2002-01-25 | 2006-05-10 | 王子製紙株式会社 | メラニン生成抑制剤 |
JP2003221339A (ja) | 2002-01-29 | 2003-08-05 | Oji Paper Co Ltd | 抗炎症剤 |
ITMI20031618A1 (it) * | 2003-08-06 | 2005-02-07 | Inalco Spa | Derivati polisaccaridici dotati di alta attivita' |
EP1748781B1 (en) * | 2004-05-27 | 2012-12-19 | Baxter International Inc. | Methods for treating bleeding disorders using sulfated polysaccharides |
ES2308536T3 (es) | 2004-08-05 | 2008-12-01 | Ivax Drug Research Institute Ltd | Glicosidos polisulfatados y sales de los mismos. |
US20060194759A1 (en) | 2005-02-25 | 2006-08-31 | Eidelson Stewart G | Topical compositions and methods for treating pain and inflammation |
CA2616230A1 (en) | 2005-07-22 | 2007-02-01 | Trf Pharma, Inc. | Method for treating sickle cell disease and sickle cell disease sequelae |
PT2010220T (pt) | 2006-04-03 | 2022-05-20 | Ceva Animal Health Pty Ltd | Formulações de polisulfato de pentosano estabilizado (pps) |
GB0610350D0 (en) * | 2006-05-25 | 2006-07-05 | Univ Liverpool | prevention and/or treatment of neuodegenerative disorders |
US20100055060A1 (en) | 2006-11-27 | 2010-03-04 | Naoyuki Yoshida | Cosmetic composition |
WO2008107906A1 (en) | 2007-03-06 | 2008-09-12 | Alembic Limited | Process for the preparation of pentosan polysulfate or salts thereof |
FI121811B (fi) | 2007-06-01 | 2011-04-29 | Upm Kymmene Corp | Uudet dispersiot ja menetelmä niiden valmistamiseksi |
HUP0900072A2 (hu) | 2009-02-06 | 2010-09-28 | Egis Gyogyszergyar Nyilvanosan | Transzdermális gyógyszerkészítmények |
WO2009087581A1 (en) | 2008-01-04 | 2009-07-16 | Alembic Limited | An improved process for the preparation of pentosan polysulfate or salts thereof |
JP2009196915A (ja) | 2008-02-20 | 2009-09-03 | Ezaki Glico Co Ltd | 化粧品用組成物 |
AU2008100730B4 (en) | 2008-07-04 | 2008-10-02 | Parnell Technologies Pty Ltd | Sulfated polysaccharide compound for clinical use and the preparation thereof |
FR2935386B1 (fr) | 2008-08-26 | 2010-09-10 | Sanofi Aventis | Nouveaux polysaccharides a activite antithrombotique comprenant une liaion covalente avec une chaine amine |
JP4884559B2 (ja) | 2009-02-02 | 2012-02-29 | 大塚化学株式会社 | 低分子量多硫酸化ヒアルロン酸誘導体及びこれを含有する医薬 |
CN102061323B (zh) | 2010-11-10 | 2013-09-25 | 山东龙力生物科技股份有限公司 | 一种植物木质纤维素的综合利用工艺 |
WO2012101544A1 (en) | 2011-01-29 | 2012-08-02 | Alembic Pharmaceuticals Limited | An improved process for the preparation of pentosan polysulfate or salts thereof |
WO2012114349A1 (en) | 2011-02-23 | 2012-08-30 | Cadila Healthcare Limited | An improved process for the preparation of pentosan polysulfate sodium |
CN102766225B (zh) | 2011-05-06 | 2015-08-05 | 上海医药工业研究院 | 一种戊聚糖聚硫酸钠的制备方法以及一种寡聚木糖 |
WO2013186857A1 (ja) | 2012-06-12 | 2013-12-19 | 株式会社リボミック | Fgf2に対するアプタマー及びその使用 |
ITMI20130112A1 (it) * | 2013-01-24 | 2014-07-25 | Chemi Spa | Metodo di qualificazione di preparazioni di pentosan polifosfato, sue materie prime e processi di produzione |
JO3529B1 (ar) | 2013-02-08 | 2020-07-05 | Amgen Res Munich Gmbh | مضاد التصاق خلايا الدم البيض من أجل التخفيف من الاثار السلبية الممكنة الناتجة عن مجالات ارتباط cd3- المحدد |
JP6132302B2 (ja) | 2013-05-28 | 2017-05-24 | リーディアント・バイオサイエンシーズ・ソシエタ・アノニマLeadiant Biosciences S.A. | 抗血管新生活性を有し、抗凝血効果を有さない、ヘパラナーゼ阻害剤としての部分的に脱硫酸化されたグリコサミノグリカンの誘導体 |
CN103320548A (zh) | 2013-06-24 | 2013-09-25 | 稼禾生物股份有限公司 | 一种利用农作物秸秆制备低聚木糖和纤维素的方法 |
JP6403317B2 (ja) | 2013-07-19 | 2018-10-10 | 学校法人慶應義塾 | 抗腫瘍剤 |
ES2907126T3 (es) * | 2015-05-20 | 2022-04-22 | Chemi Spa | Proceso para la preparación de polisacáridos |
AU2016267264A1 (en) | 2015-05-27 | 2017-12-07 | Vanguard Therapeutics, Inc. | Pentosan polysulfate sodium for the treatment of sickle cell disease |
CN106832020A (zh) * | 2015-12-04 | 2017-06-13 | 长春工业大学 | 一种玉米秸秆戊聚糖硫酸酯的制备工艺 |
CN105907896B (zh) * | 2016-05-16 | 2019-11-12 | 中国科学院广州能源研究所 | 一种利用木质纤维原料联产高浓度木糖和低聚木糖的方法 |
JP6225321B1 (ja) | 2016-08-31 | 2017-11-08 | 王子ホールディングス株式会社 | ポリ硫酸ペントサンの製造方法 |
AU2017321817B2 (en) | 2016-08-31 | 2022-12-15 | Oji Holdings Corporation | Production method for acidic xylooligosaccharide, and acidic xylooligosaccharide |
JP6281659B1 (ja) | 2017-02-28 | 2018-02-21 | 王子ホールディングス株式会社 | ポリ硫酸ペントサン、医薬組成物及び抗凝固剤 |
-
2017
- 2017-03-03 JP JP2017040067A patent/JP6225321B1/ja active Active
- 2017-08-31 SG SG11202001822WA patent/SG11202001822WA/en unknown
- 2017-08-31 WO PCT/JP2017/031434 patent/WO2018043668A1/ja active Application Filing
- 2017-08-31 MX MX2020002287A patent/MX2020002287A/es unknown
- 2017-08-31 AU AU2017321818A patent/AU2017321818B2/en active Active
- 2017-08-31 JP JP2018516079A patent/JP6432709B2/ja active Active
- 2017-08-31 KR KR1020207008632A patent/KR102591794B1/ko active IP Right Grant
- 2017-08-31 CN CN201780094371.2A patent/CN111065654B/zh active Active
- 2017-08-31 US US16/643,265 patent/US11312790B2/en active Active
- 2017-08-31 EP EP17846672.8A patent/EP3677599A4/en active Pending
- 2017-08-31 CA CA3074419A patent/CA3074419C/en active Active
- 2017-08-31 BR BR112020003899-7A patent/BR112020003899B1/pt active IP Right Grant
Also Published As
Publication number | Publication date |
---|---|
JPWO2018043668A1 (ja) | 2018-08-30 |
CN111065654A (zh) | 2020-04-24 |
EP3677599A1 (en) | 2020-07-08 |
KR102591794B1 (ko) | 2023-10-19 |
JP6432709B2 (ja) | 2018-12-05 |
AU2017321818A1 (en) | 2020-03-26 |
BR112020003899A2 (pt) | 2020-09-01 |
KR20200044896A (ko) | 2020-04-29 |
CA3074419C (en) | 2023-09-26 |
WO2018043668A1 (ja) | 2018-03-08 |
SG11202001822WA (en) | 2020-04-29 |
JP2018039973A (ja) | 2018-03-15 |
CA3074419A1 (en) | 2018-03-08 |
US11312790B2 (en) | 2022-04-26 |
BR112020003899B1 (pt) | 2023-04-18 |
AU2017321818B2 (en) | 2022-12-08 |
US20200332027A1 (en) | 2020-10-22 |
CN111065654B (zh) | 2022-08-26 |
BR112020003899A8 (pt) | 2023-03-07 |
JP6225321B1 (ja) | 2017-11-08 |
EP3677599A4 (en) | 2021-03-31 |
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