MX2019002474A - Composiciones de agente de unión de portador-ligando-1 de muerte programada y métodos de uso de las mismas para el tratamiento de cánceres. - Google Patents
Composiciones de agente de unión de portador-ligando-1 de muerte programada y métodos de uso de las mismas para el tratamiento de cánceres.Info
- Publication number
- MX2019002474A MX2019002474A MX2019002474A MX2019002474A MX2019002474A MX 2019002474 A MX2019002474 A MX 2019002474A MX 2019002474 A MX2019002474 A MX 2019002474A MX 2019002474 A MX2019002474 A MX 2019002474A MX 2019002474 A MX2019002474 A MX 2019002474A
- Authority
- MX
- Mexico
- Prior art keywords
- carrier
- binding agent
- agent compositions
- treating cancers
- methods
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/51—Nanocapsules; Nanoparticles
- A61K9/5107—Excipients; Inactive ingredients
- A61K9/513—Organic macromolecular compounds; Dendrimers
- A61K9/5169—Proteins, e.g. albumin, gelatin
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
- C07K16/2818—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against CD28 or CD152
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/39558—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/51—Nanocapsules; Nanoparticles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
- C07K16/2827—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against B7 molecules, e.g. CD80, CD86
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Oncology (AREA)
- Physics & Mathematics (AREA)
- Nanotechnology (AREA)
- Optics & Photonics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
En el presente documento se describen composiciones de agentes de union y proteinas portadoras, y opcionalmente al menos un agente terapeutico, y metodos para fabricar y usar el mismo, en particular, como agente terapeutico contra el cancer; tambien se describen composiciones liofilizadas de agentes de union y proteinas portadoras, y opcionalmente al menos un agente terapeutico, y metodos para hacer y usar el mismo, en particular, como agente terapéutico contra el cancer; tambien se describen metodos para tratar y/o aumentar la eficacia terapeutica de una inmunoterapia de un paciente que padece un cancer que expresa PD-L1 o PD-L2 administrando al paciente una composicion de nanoparticulas y una inmunoterapia con PD-1.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201662382731P | 2016-09-01 | 2016-09-01 | |
PCT/US2017/049746 WO2018045239A1 (en) | 2016-09-01 | 2017-08-31 | Carrier-pd-l1 binding agent compositions for treating cancers |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2019002474A true MX2019002474A (es) | 2019-09-18 |
Family
ID=60009705
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2019002474A MX2019002474A (es) | 2016-09-01 | 2017-08-31 | Composiciones de agente de unión de portador-ligando-1 de muerte programada y métodos de uso de las mismas para el tratamiento de cánceres. |
Country Status (11)
Country | Link |
---|---|
US (2) | US11548946B2 (es) |
EP (2) | EP3506942B1 (es) |
JP (2) | JP7525999B2 (es) |
KR (2) | KR20220151022A (es) |
CN (1) | CN109890419A (es) |
AU (1) | AU2017318668A1 (es) |
CA (1) | CA3035378A1 (es) |
ES (1) | ES2937291T3 (es) |
MX (1) | MX2019002474A (es) |
RU (1) | RU2019109211A (es) |
WO (1) | WO2018045239A1 (es) |
Families Citing this family (27)
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EP2707030B1 (en) | 2011-05-09 | 2020-02-19 | Mayo Foundation For Medical Education And Research | Cancer treatments |
CA2917407C (en) | 2012-10-01 | 2023-03-14 | Mayo Foundation For Medical Education And Research | Complexes containing albumin-containing nanoparticles and antibodies to treat cancer |
CA2952424C (en) | 2014-06-16 | 2019-07-23 | Mayo Foundation For Medical Education And Research | Treating myelomas |
US9446148B2 (en) | 2014-10-06 | 2016-09-20 | Mayo Foundation For Medical Education And Research | Carrier-antibody compositions and methods of making and using the same |
AU2016270559B2 (en) | 2015-06-04 | 2020-12-10 | Crititech, Inc. | Collection device and methods for use |
TW201707725A (zh) | 2015-08-18 | 2017-03-01 | 美國馬友醫藥教育研究基金會 | 載體-抗體組合物及其製造及使用方法 |
TW201713360A (en) | 2015-10-06 | 2017-04-16 | Mayo Foundation | Methods of treating cancer using compositions of antibodies and carrier proteins |
WO2017120501A1 (en) | 2016-01-07 | 2017-07-13 | Mayo Foundation For Medical Education And Research | Methods of treating cancer with interferon |
EP3413874A4 (en) | 2016-02-12 | 2020-01-22 | Mayo Foundation for Medical Education and Research | HEMATOLOGICAL CANCER TREATMENTS |
AU2017238118A1 (en) | 2016-03-21 | 2018-10-11 | Mayo Foundation For Medical Education And Research | Methods for improving the therapeutic index for a chemotherapeutic drug |
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US10618969B2 (en) | 2016-04-06 | 2020-04-14 | Mayo Foundation For Medical Education And Research | Carrier-binding agent compositions and methods of making and using the same |
US11160876B2 (en) | 2016-09-01 | 2021-11-02 | Mayo Foundation For Medical Education And Research | Methods and compositions for targeting t-cell cancers |
JP7525999B2 (ja) | 2016-09-01 | 2024-07-31 | マヨ ファウンデーション フォー メディカル エデュケーション アンド リサーチ | キャリアー-pd-l1結合剤組成物及び癌を処置する為にそれを使用する方法 |
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EP3749331A4 (en) * | 2018-02-06 | 2021-08-04 | Mayo Foundation for Medical Education and Research | ANTIBODY PEPTIDE COMPLEX AND THEIR USES |
CN109512798B (zh) * | 2019-01-15 | 2022-05-13 | 南京从一医药科技有限公司 | 一种用于抗肿瘤免疫治疗的药物组合物纳米体系 |
CN110623942B (zh) * | 2019-09-30 | 2020-09-22 | 武汉大学 | 一种全反式维甲酸纳米药物制剂、其制备方法及应用 |
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- 2017-08-31 KR KR1020227037674A patent/KR20220151022A/ko not_active Application Discontinuation
- 2017-08-31 KR KR1020197009302A patent/KR102462041B1/ko active IP Right Grant
- 2017-08-31 EP EP17778387.5A patent/EP3506942B1/en active Active
- 2017-08-31 ES ES17778387T patent/ES2937291T3/es active Active
- 2017-08-31 AU AU2017318668A patent/AU2017318668A1/en not_active Withdrawn
- 2017-08-31 CN CN201780067542.2A patent/CN109890419A/zh active Pending
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KR102462041B1 (ko) | 2022-11-02 |
KR20220151022A (ko) | 2022-11-11 |
RU2019109211A (ru) | 2020-10-01 |
US11548946B2 (en) | 2023-01-10 |
EP3506942B1 (en) | 2022-11-16 |
JP2022082806A (ja) | 2022-06-02 |
KR20190129818A (ko) | 2019-11-20 |
JP2019526578A (ja) | 2019-09-19 |
ES2937291T3 (es) | 2023-03-27 |
US20230159640A1 (en) | 2023-05-25 |
CN109890419A (zh) | 2019-06-14 |
EP4177271A1 (en) | 2023-05-10 |
JP7525999B2 (ja) | 2024-07-31 |
CA3035378A1 (en) | 2018-03-08 |
EP3506942A1 (en) | 2019-07-10 |
US20190202916A1 (en) | 2019-07-04 |
WO2018045239A1 (en) | 2018-03-08 |
AU2017318668A1 (en) | 2019-03-21 |
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