MX2018004144A - Una composicion para aclarar la piel. - Google Patents

Una composicion para aclarar la piel.

Info

Publication number
MX2018004144A
MX2018004144A MX2018004144A MX2018004144A MX2018004144A MX 2018004144 A MX2018004144 A MX 2018004144A MX 2018004144 A MX2018004144 A MX 2018004144A MX 2018004144 A MX2018004144 A MX 2018004144A MX 2018004144 A MX2018004144 A MX 2018004144A
Authority
MX
Mexico
Prior art keywords
skin lightening
niacinamide
melanocytes
composition
melanosome transfer
Prior art date
Application number
MX2018004144A
Other languages
English (en)
Other versions
MX365369B (es
Inventor
Kunjupillai Balu
Damodaran Anita
Kumar Joshi Manoj
Shariff Rezwan
Original Assignee
Unilever Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Unilever Nv filed Critical Unilever Nv
Publication of MX2018004144A publication Critical patent/MX2018004144A/es
Publication of MX365369B publication Critical patent/MX365369B/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/4906Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom
    • A61K8/4926Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom having six membered rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67Vitamins
    • A61K8/673Vitamin B group
    • A61K8/675Vitamin B3 or vitamin B3 active, e.g. nicotinamide, nicotinic acid, nicotinyl aldehyde
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4402Non condensed pyridines; Hydrogenated derivatives thereof only substituted in position 2, e.g. pheniramine, bisacodyl
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/455Nicotinic acids, e.g. niacin; Derivatives thereof, e.g. esters, amides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/02Local antiseptics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q15/00Anti-perspirants or body deodorants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A61Q17/005Antimicrobial preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/02Preparations for care of the skin for chemically bleaching or whitening the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/10Washing or bathing preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/70Biological properties of the composition as a whole
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Dermatology (AREA)
  • Birds (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Communicable Diseases (AREA)
  • Cosmetics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

La presente invención se encuentra en el campo de las composiciones para el cuidado personal; en particular, de composiciones para aclarar la piel. Se cree que la niacinamida reduce la transferencia de los melanosomas desde los melanocitos hacia los queratinocitos, produciendo así el aclaramiento de la piel. Sin embargo, se sabe que la niacinamida tiene un efecto directo escaso o nulo sobre el contenido de melanina en los melanocitos. De este modo, sigue deseándose obtener una composición que presente múltiples modos de acción, que combine la reducción de transferencia de los melanosomas con la reducción del contenido de melanina en los melanocitos. Por consiguiente, constituye un objeto de la presente invención proporcionar una composición con cantidades sinérgicas de picolinamida y niacinamida, que proporcionen una mejor inhibición de la transferencia de melanosoma. Se ha hallado que se obtiene un efecto sinérgico de aclaramiento de la piel cuando la niacinamida se combina con su isómero, la picolinamida.
MX2018004144A 2015-10-05 2016-10-04 Una composición para aclarar la piel. MX365369B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP15188360 2015-10-05
PCT/EP2016/073617 WO2017060211A1 (en) 2015-10-05 2016-10-04 A skin lightening composition

Publications (2)

Publication Number Publication Date
MX2018004144A true MX2018004144A (es) 2018-06-13
MX365369B MX365369B (es) 2019-05-31

Family

ID=54256684

Family Applications (2)

Application Number Title Priority Date Filing Date
MX2018004144A MX365369B (es) 2015-10-05 2016-10-04 Una composición para aclarar la piel.
MX2018004143A MX2018004143A (es) 2015-10-05 2016-10-04 Composicion que comprende niacinamida y picolinamida.

Family Applications After (1)

Application Number Title Priority Date Filing Date
MX2018004143A MX2018004143A (es) 2015-10-05 2016-10-04 Composicion que comprende niacinamida y picolinamida.

Country Status (13)

Country Link
US (3) US10952952B2 (es)
EP (2) EP3359261B1 (es)
JP (2) JP6880011B2 (es)
KR (1) KR102643373B1 (es)
CN (2) CN108136232B (es)
AR (1) AR106261A1 (es)
BR (1) BR112018005742B1 (es)
CA (2) CA3000880A1 (es)
EA (2) EA035440B1 (es)
MX (2) MX365369B (es)
PH (1) PH12018500619B1 (es)
WO (2) WO2017060211A1 (es)
ZA (2) ZA201802005B (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6880011B2 (ja) 2015-10-05 2021-06-02 ユニリーバー・ナームローゼ・ベンノートシヤープ 皮膚美白組成物
WO2019121529A1 (en) 2017-12-18 2019-06-27 Unilever N.V. A topical composition
US20220362127A1 (en) * 2019-07-12 2022-11-17 Conopco, Inc., D/B/A Unilever Bioenergetic combinations and methods of using same
WO2021249760A1 (en) * 2020-06-10 2021-12-16 Unilever Ip Holdings B.V. A cosmetic composition comprising 6-methyl-picolinamide
US11696889B2 (en) 2020-08-07 2023-07-11 David Levy Botanical antimicrobial composition
WO2023175061A1 (en) * 2022-03-18 2023-09-21 Unilever Ip Holdings B.V. A skin brightening composition

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1370236A (en) * 1972-01-11 1974-10-16 Unilever Ltd Skin composition
GB1533119A (en) * 1975-04-10 1978-11-22 Unilever Ltd Skin lightening compositions
GB8910366D0 (en) * 1989-05-05 1989-06-21 Unilever Plc Skin composition
TW233264B (es) 1992-02-03 1994-11-01 Otsuka Pharma Co Ltd
US5411741A (en) * 1993-07-29 1995-05-02 Zaias; Nardo Method and composition for skin depigmentation
WO1999047141A1 (en) 1998-03-16 1999-09-23 The Procter & Gamble Company Method of treating skin irritation
JP2003529590A (ja) 2000-03-21 2003-10-07 アスション デヴェロップメント エーピーエス ピリジンカルボキシ誘導体およびh2ヒスタミン受容体アンタゴニストからなる化学的複合体
US20030105034A1 (en) 2001-07-05 2003-06-05 Astion Deveopment A/S Pyridine carboxy derivatives and an aminosugar
FR2827763B1 (fr) 2001-07-24 2005-09-23 Cs Substance alkyloside inhibant la fixation de microorganismes, utilisation topique et composition contenant au moins une telle substance
JP3908969B2 (ja) 2002-03-18 2007-04-25 ピアス株式会社 化粧料
JP4589721B2 (ja) 2002-06-20 2010-12-01 アスティオン デルマトロジー エイ/エス ポリヒドロキシアルカンの脂肪酸エステルおよびピリジンカルボキシ誘導体の新規複合体
JP2004123554A (ja) * 2002-09-30 2004-04-22 Pias Arise Kk 皮膚バリア機能改善物質、皮膚のしわ改善物質、および該物質を含む皮膚外用剤、化粧料および医薬部外品
US20090105188A1 (en) * 2007-10-17 2009-04-23 Nationwide Children's Hospital, Inc. Compositions and Methods for Treating Necrotizing Enterocolitis
US20090317341A1 (en) * 2008-06-18 2009-12-24 Conopco, Inc., D/B/A Unilever Compositions for Lightening Skin Color
JP2011526900A (ja) 2008-06-30 2011-10-20 イーエルシー マネージメント エルエルシー イソニコチンアミドを含む外用組成物
EP3330252B1 (en) * 2008-11-11 2020-02-12 Signum Biosciences, Inc. Isoprenyl compounds and methods thereof
US20130052162A1 (en) * 2010-04-20 2013-02-28 Cedars-Sinai Medical Center Boosting immune defense by upregulating ccaat/enhancer binding protein epsilon
EP2522331A1 (en) * 2011-05-09 2012-11-14 DSM IP Assets B.V. Use of resveratrol and niacinamide
WO2013030794A2 (en) * 2011-08-31 2013-03-07 Behrooz Kasraee Use of substituted pyridines as skin depigmenting compounds
US20140161750A1 (en) * 2012-12-12 2014-06-12 Thomas Christopher Balshi Sunscreen composition with pigment correcting properties
EP2742942B1 (en) * 2012-12-14 2019-05-22 Unilever N.V. Niacinamide for inducing generation of antimicrobial peptides
EP3060311B1 (en) * 2013-10-24 2019-05-22 The Procter and Gamble Company Skin lightening cosmetic compositions and methods
BR112016024400A2 (pt) 2014-05-12 2017-08-15 Unilever Nv uso de niacinamida, niacinamida e método para melhorar a proteção do couro cabeludo
JP6880011B2 (ja) * 2015-10-05 2021-06-02 ユニリーバー・ナームローゼ・ベンノートシヤープ 皮膚美白組成物

Also Published As

Publication number Publication date
CN108135824A (zh) 2018-06-08
WO2017060211A1 (en) 2017-04-13
US20200230045A1 (en) 2020-07-23
MX2018004143A (es) 2018-06-13
KR20180054647A (ko) 2018-05-24
AR106261A1 (es) 2017-12-27
CA3000880A1 (en) 2017-04-13
CN108135824B (zh) 2021-09-17
CA3000296A1 (en) 2017-04-13
PH12018500619A1 (en) 2018-10-01
EP3359124B1 (en) 2020-06-03
EP3359261A1 (en) 2018-08-15
EA201890886A1 (ru) 2018-09-28
EA035789B1 (ru) 2020-08-11
US20180296457A1 (en) 2018-10-18
KR102643373B1 (ko) 2024-03-07
US11298312B2 (en) 2022-04-12
MX365369B (es) 2019-05-31
EP3359261B1 (en) 2019-05-15
BR112018005742A2 (pt) 2018-10-09
JP2018529741A (ja) 2018-10-11
CN108136232A (zh) 2018-06-08
BR112018005742B1 (pt) 2021-11-16
JP2018529735A (ja) 2018-10-11
EA035440B1 (ru) 2020-06-15
ZA201802005B (en) 2019-07-31
ZA201802233B (en) 2019-07-31
JP6907196B2 (ja) 2021-07-21
CN108136232B (zh) 2021-08-13
WO2017060213A1 (en) 2017-04-13
US20180280278A1 (en) 2018-10-04
EA201890889A1 (ru) 2018-09-28
PH12018500619B1 (en) 2018-10-01
US10660840B2 (en) 2020-05-26
EP3359124A1 (en) 2018-08-15
US10952952B2 (en) 2021-03-23
JP6880011B2 (ja) 2021-06-02

Similar Documents

Publication Publication Date Title
PH12018500619B1 (en) A skin lightening composition
MX2022012374A (es) Composiciones multi-suplementos.
EA201591367A1 (ru) Соединения резорцина для дерматологического применения
ZA201805792B (en) Taurine and aloe synergistic anti-irritant compositions and methods
PH12019501193A1 (en) Use of chelating agents for improving color stability of resorcinol
MX2017013538A (es) Metodos y composiciones concentradas para la limpieza personal.
MX2019008999A (es) Composicion inyectable para prevenir la perdida del pelo o estimular el crecimiento del pelo.
MY196718A (en) Composition for skin whitening comprising b-mangostin as effective ingredient
PH12017501200A1 (en) A skin lightening composition comprising niacinamide and ilomastat
MX2015011991A (es) Combinaciones de alquilamidotiazoles y sustancias aromaticas.
PH12020500055A1 (en) A personal care composition
MX345695B (es) Heterociclocarbonilaminotiazoles, preparaciones cosmeticas o dermatologicas que contienen los mismos y su uso para el control y la profilaxis de pigmentacion indeseada de la piel.
PH12017500996A1 (en) A skin lightening composition
PH12016501811B1 (en) Cosmetic composition for skin moisturizing containing minerals and quinoa extract
TW201129394A (en) Composition for inhibiting melanogenesis and use thereof
GB2564990A8 (en) Topical compositions for neuropathic pain
NZ746011A (en) Glycoalkaloid combinations and various uses thereof
MX2018007468A (es) Composiciones de colageno 7 y metodos para usar las mismas.
BR112017018828A2 (pt) peptídeo possuindo atividade de clareamento da pele e uso do mesmo
MX2018000538A (es) Composicion antimicrobiana.
MX2020005682A (es) Extracto de helichrysum gymnocephalum para el tratamiento y/o la prevencion de dermatosis inflamatorias.
MX2019005977A (es) Composicion cosmetica antisenescencia celular, uso de derivados de casearia sylvestris y/o hymenaea courbaril, metodo de prevencion de senescencia celular y metodo para la modulacion de la expresion de b-galactosidasa, p16, p21 y/o interleucina 8 (il-8).
MX370875B (es) Composición cosmética reductiva de aplicación tópica que contiene queratina y azufre.
MX2017007729A (es) Composicion cosmetica anhidra para aplicacion topica.
PH12018501110B1 (en) A cosmetic mask

Legal Events

Date Code Title Description
FG Grant or registration