AR106261A1 - Una composición para aclarar la piel - Google Patents

Una composición para aclarar la piel

Info

Publication number
AR106261A1
AR106261A1 ARP160103044A ARP160103044A AR106261A1 AR 106261 A1 AR106261 A1 AR 106261A1 AR P160103044 A ARP160103044 A AR P160103044A AR P160103044 A ARP160103044 A AR P160103044A AR 106261 A1 AR106261 A1 AR 106261A1
Authority
AR
Argentina
Prior art keywords
niacinamide
skin
picolinamide
composition
skin lightening
Prior art date
Application number
ARP160103044A
Other languages
English (en)
Inventor
Shariff Rezwan
Kunjupillai Balu
Kumar Joshi Manoj
Damodaran Anita
Original Assignee
Unilever Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Unilever Nv filed Critical Unilever Nv
Publication of AR106261A1 publication Critical patent/AR106261A1/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67Vitamins
    • A61K8/673Vitamin B group
    • A61K8/675Vitamin B3 or vitamin B3 active, e.g. nicotinamide, nicotinic acid, nicotinyl aldehyde
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4402Non condensed pyridines; Hydrogenated derivatives thereof only substituted in position 2, e.g. pheniramine, bisacodyl
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/455Nicotinic acids, e.g. niacin; Derivatives thereof, e.g. esters, amides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/4906Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom
    • A61K8/4926Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom having six membered rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/02Local antiseptics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q15/00Anti-perspirants or body deodorants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A61Q17/005Antimicrobial preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/02Preparations for care of the skin for chemically bleaching or whitening the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/10Washing or bathing preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/70Biological properties of the composition as a whole
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Dermatology (AREA)
  • Birds (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Cosmetics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Composiciones para el cuidado personal; en particular, a composiciones para aclarar la piel. Se cree que la niacinamida reduce la transferencia de los melanosomas desde los melanocitos hacia los queratinocitos, produciendo así el aclaramiento de la piel. Sin embargo, se sabe que la niacinamida tiene un efecto directo escaso o nulo sobre el contenido de melanina en los melanocitos. Obtener una composición que presente múltiples modos de acción, que combine la reducción de transferencia de los melanosomas con la reducción del contenido de melanina en los melanocitos. Una composición con cantidades sinergísticas de picolinamida y niacinamida, capaz de ofrecer una mejor inhibición de la transferencia de melanosoma. Se obtiene un efecto de aclaramiento sinergístico de la piel cuando la niacinamida se combina con su isómero, la picolinamida. Reivindicación 1: Una composición para aclarar la piel que comprende: a) 0,1 a 10% en peso de picolinamida y b) 0,1 a 10% en peso de niacinamida. Reivindicación 4: Una composición para aclarar la piel de acuerdo con la reivindicación 1 en la cual la relación molar de picolinamida a niacinamida varía de 20:1 a 1:20. Reivindicación 7: Una composición para aclarar la piel de acuerdo con una cualquiera de las reivindicaciones 1 a 6, que comprende; además, un agente de beneficio para la piel.
ARP160103044A 2015-10-05 2016-10-05 Una composición para aclarar la piel AR106261A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP15188360 2015-10-05

Publications (1)

Publication Number Publication Date
AR106261A1 true AR106261A1 (es) 2017-12-27

Family

ID=54256684

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP160103044A AR106261A1 (es) 2015-10-05 2016-10-05 Una composición para aclarar la piel

Country Status (13)

Country Link
US (3) US10952952B2 (es)
EP (2) EP3359261B1 (es)
JP (2) JP6907196B2 (es)
KR (1) KR102643373B1 (es)
CN (2) CN108136232B (es)
AR (1) AR106261A1 (es)
BR (1) BR112018005742B1 (es)
CA (2) CA3000296A1 (es)
EA (2) EA035440B1 (es)
MX (2) MX2018004143A (es)
PH (1) PH12018500619B1 (es)
WO (2) WO2017060211A1 (es)
ZA (2) ZA201802005B (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2018004143A (es) * 2015-10-05 2018-06-13 Unilever Nv Composicion que comprende niacinamida y picolinamida.
CN111491612B (zh) 2017-12-18 2023-10-20 联合利华知识产权控股有限公司 局部组合物
CN114096233A (zh) * 2019-07-12 2022-02-25 联合利华知识产权控股有限公司 生物能量的组合和使用其的方法
WO2021249760A1 (en) * 2020-06-10 2021-12-16 Unilever Ip Holdings B.V. A cosmetic composition comprising 6-methyl-picolinamide
US11696889B2 (en) 2020-08-07 2023-07-11 David Levy Botanical antimicrobial composition
WO2023175061A1 (en) * 2022-03-18 2023-09-21 Unilever Ip Holdings B.V. A skin brightening composition

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1370236A (en) * 1972-01-11 1974-10-16 Unilever Ltd Skin composition
GB1533119A (en) * 1975-04-10 1978-11-22 Unilever Ltd Skin lightening compositions
GB8910366D0 (en) * 1989-05-05 1989-06-21 Unilever Plc Skin composition
TW233264B (es) 1992-02-03 1994-11-01 Otsuka Pharma Co Ltd
US5411741A (en) * 1993-07-29 1995-05-02 Zaias; Nardo Method and composition for skin depigmentation
AU3082699A (en) 1998-03-16 1999-10-11 Procter & Gamble Company, The Method of treating skin irritation
JP2003529590A (ja) 2000-03-21 2003-10-07 アスション デヴェロップメント エーピーエス ピリジンカルボキシ誘導体およびh2ヒスタミン受容体アンタゴニストからなる化学的複合体
US20030105034A1 (en) 2001-07-05 2003-06-05 Astion Deveopment A/S Pyridine carboxy derivatives and an aminosugar
FR2827763B1 (fr) 2001-07-24 2005-09-23 Cs Substance alkyloside inhibant la fixation de microorganismes, utilisation topique et composition contenant au moins une telle substance
JP3908969B2 (ja) 2002-03-18 2007-04-25 ピアス株式会社 化粧料
DE60308891T2 (de) 2002-06-20 2007-05-24 Astion Dermatology A/S Neue komplexe von polyhydroxyalkanfettsäureestern und niacinamid
JP2004123554A (ja) 2002-09-30 2004-04-22 Pias Arise Kk 皮膚バリア機能改善物質、皮膚のしわ改善物質、および該物質を含む皮膚外用剤、化粧料および医薬部外品
US20090105188A1 (en) 2007-10-17 2009-04-23 Nationwide Children's Hospital, Inc. Compositions and Methods for Treating Necrotizing Enterocolitis
US20090317341A1 (en) 2008-06-18 2009-12-24 Conopco, Inc., D/B/A Unilever Compositions for Lightening Skin Color
WO2010002586A2 (en) 2008-06-30 2010-01-07 Elc Management Llc Topical compositions comprising isonicotinamide
AU2009314165B2 (en) * 2008-11-11 2014-05-15 Signum Biosciences, Inc. Isoprenyl compounds and methods thereof
WO2011133692A1 (en) 2010-04-20 2011-10-27 Cedars-Sinai Medical Center Boosting immune defense by upregulating ccaat/enhancer binding protein epsilon
EP2522331A1 (en) 2011-05-09 2012-11-14 DSM IP Assets B.V. Use of resveratrol and niacinamide
WO2013030794A2 (en) * 2011-08-31 2013-03-07 Behrooz Kasraee Use of substituted pyridines as skin depigmenting compounds
US20140161750A1 (en) * 2012-12-12 2014-06-12 Thomas Christopher Balshi Sunscreen composition with pigment correcting properties
EP3120850B1 (en) * 2012-12-14 2018-11-07 Unilever N.V. Niacinamide for inducing generation of antimicrobial peptides
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MX2018004143A (es) * 2015-10-05 2018-06-13 Unilever Nv Composicion que comprende niacinamida y picolinamida.

Also Published As

Publication number Publication date
EP3359261B1 (en) 2019-05-15
CN108135824A (zh) 2018-06-08
WO2017060213A1 (en) 2017-04-13
US20200230045A1 (en) 2020-07-23
MX2018004143A (es) 2018-06-13
US20180280278A1 (en) 2018-10-04
JP6880011B2 (ja) 2021-06-02
EA035440B1 (ru) 2020-06-15
ZA201802005B (en) 2019-07-31
CA3000880A1 (en) 2017-04-13
KR20180054647A (ko) 2018-05-24
EP3359124A1 (en) 2018-08-15
CN108135824B (zh) 2021-09-17
US10660840B2 (en) 2020-05-26
PH12018500619A1 (en) 2018-10-01
EA201890889A1 (ru) 2018-09-28
BR112018005742A2 (pt) 2018-10-09
ZA201802233B (en) 2019-07-31
EA201890886A1 (ru) 2018-09-28
PH12018500619B1 (en) 2018-10-01
CN108136232B (zh) 2021-08-13
US20180296457A1 (en) 2018-10-18
MX365369B (es) 2019-05-31
KR102643373B1 (ko) 2024-03-07
US11298312B2 (en) 2022-04-12
CA3000296A1 (en) 2017-04-13
JP2018529735A (ja) 2018-10-11
EP3359261A1 (en) 2018-08-15
EP3359124B1 (en) 2020-06-03
US10952952B2 (en) 2021-03-23
JP2018529741A (ja) 2018-10-11
CN108136232A (zh) 2018-06-08
JP6907196B2 (ja) 2021-07-21
MX2018004144A (es) 2018-06-13
BR112018005742B1 (pt) 2021-11-16
EA035789B1 (ru) 2020-08-11
WO2017060211A1 (en) 2017-04-13

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