MX2017007243A - Metodos para desarrollo y uso de unidades micro-agregadas de celulas funcionales polarizadas minimamente en aplicaciones en tejidos utilizando celulas troncales epiteliales que expresan lgr4, lgr5 y lgr6. - Google Patents
Metodos para desarrollo y uso de unidades micro-agregadas de celulas funcionales polarizadas minimamente en aplicaciones en tejidos utilizando celulas troncales epiteliales que expresan lgr4, lgr5 y lgr6.Info
- Publication number
- MX2017007243A MX2017007243A MX2017007243A MX2017007243A MX2017007243A MX 2017007243 A MX2017007243 A MX 2017007243A MX 2017007243 A MX2017007243 A MX 2017007243A MX 2017007243 A MX2017007243 A MX 2017007243A MX 2017007243 A MX2017007243 A MX 2017007243A
- Authority
- MX
- Mexico
- Prior art keywords
- applications
- micro
- troncal
- epitelial
- lgr6
- Prior art date
Links
- 101001063463 Homo sapiens Leucine-rich repeat-containing G-protein coupled receptor 4 Proteins 0.000 title 1
- 101001063456 Homo sapiens Leucine-rich repeat-containing G-protein coupled receptor 5 Proteins 0.000 title 1
- 101000981765 Homo sapiens Leucine-rich repeat-containing G-protein coupled receptor 6 Proteins 0.000 title 1
- 102100031035 Leucine-rich repeat-containing G-protein coupled receptor 4 Human genes 0.000 title 1
- 102100031036 Leucine-rich repeat-containing G-protein coupled receptor 5 Human genes 0.000 title 1
- 102100024140 Leucine-rich repeat-containing G-protein coupled receptor 6 Human genes 0.000 title 1
- 238000011161 development Methods 0.000 title 1
- 239000004744 fabric Substances 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 3
- 102000003688 G-Protein-Coupled Receptors Human genes 0.000 abstract 1
- 108090000045 G-Protein-Coupled Receptors Proteins 0.000 abstract 1
- 108010006444 Leucine-Rich Repeat Proteins Proteins 0.000 abstract 1
- 206010052428 Wound Diseases 0.000 abstract 1
- 208000027418 Wounds and injury Diseases 0.000 abstract 1
- 210000004027 cell Anatomy 0.000 abstract 1
- 238000002659 cell therapy Methods 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 230000035876 healing Effects 0.000 abstract 1
- 230000001900 immune effect Effects 0.000 abstract 1
- 210000004901 leucine-rich repeat Anatomy 0.000 abstract 1
- 230000001172 regenerating effect Effects 0.000 abstract 1
- 239000000758 substrate Substances 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
- 238000002054 transplantation Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0625—Epidermal cells, skin cells; Cells of the oral mucosa
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
- A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
- A61L27/3813—Epithelial cells, e.g. keratinocytes, urothelial cells
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N1/00—Preservation of bodies of humans or animals, or parts thereof
- A01N1/10—Preservation of living parts
- A01N1/12—Chemical aspects of preservation
- A01N1/122—Preservation or perfusion media
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N1/00—Preservation of bodies of humans or animals, or parts thereof
- A01N1/10—Preservation of living parts
- A01N1/12—Chemical aspects of preservation
- A01N1/122—Preservation or perfusion media
- A01N1/125—Freeze protecting agents, e.g. cryoprotectants or osmolarity regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/3604—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the human or animal origin of the biological material, e.g. hair, fascia, fish scales, silk, shellac, pericardium, pleura, renal tissue, amniotic membrane, parenchymal tissue, fetal tissue, muscle tissue, fat tissue, enamel
- A61L27/362—Skin, e.g. dermal papillae
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/54—Biologically active materials, e.g. therapeutic substances
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/412—Tissue-regenerating or healing or proliferative agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2430/00—Materials or treatment for tissue regeneration
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2513/00—3D culture
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Zoology (AREA)
- Medicinal Chemistry (AREA)
- Wood Science & Technology (AREA)
- Dermatology (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cell Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Transplantation (AREA)
- Epidemiology (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Environmental Sciences (AREA)
- Dentistry (AREA)
- Botany (AREA)
- Urology & Nephrology (AREA)
- Molecular Biology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Endocrinology (AREA)
- Diabetes (AREA)
- Materials For Medical Uses (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462086526P | 2014-12-02 | 2014-12-02 | |
| US14/954,335 US10926001B2 (en) | 2014-12-02 | 2015-11-30 | Methods related to minimally polarized functional units |
| PCT/US2015/063114 WO2016089825A1 (en) | 2014-12-02 | 2015-12-01 | Methods for development and use of minimally polarized function cell micro-aggregate units in tissue applications using lgr4, lgr5 and lgr6 expressing epithelial stem cells |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2017007243A true MX2017007243A (es) | 2018-01-25 |
Family
ID=56078499
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2017007243A MX2017007243A (es) | 2014-12-02 | 2015-12-01 | Metodos para desarrollo y uso de unidades micro-agregadas de celulas funcionales polarizadas minimamente en aplicaciones en tejidos utilizando celulas troncales epiteliales que expresan lgr4, lgr5 y lgr6. |
| MX2023001655A MX2023001655A (es) | 2014-12-02 | 2017-06-05 | Composiciones que comprenden celulas troncales que expresan lgr y usos de las mismas. |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2023001655A MX2023001655A (es) | 2014-12-02 | 2017-06-05 | Composiciones que comprenden celulas troncales que expresan lgr y usos de las mismas. |
Country Status (21)
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110913690A (zh) * | 2017-03-14 | 2020-03-24 | 朱诺治疗学股份有限公司 | 用于低温储存的方法 |
| CA3088129A1 (en) * | 2018-01-26 | 2019-08-01 | Polarityte, Inc. | Composite-interfacing biomaterial accelerant substrate |
| WO2019148143A1 (en) * | 2018-01-26 | 2019-08-01 | Polarityte, Inc. | Complex living interface-coordinated self-assembling materials (clicsam) |
| FR3082123B1 (fr) | 2018-06-07 | 2020-10-16 | Urgo Rech Innovation Et Developpement | Pansement cellularise et son procede de fabrication |
| JP2024006681A (ja) * | 2022-07-04 | 2024-01-17 | 学校法人近畿大学 | 生体材料 |
| WO2025166131A1 (en) * | 2024-02-01 | 2025-08-07 | Board Of Regents, The University Of Texas System | Compositions and methods for treating bone and muscle injuries |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20040126881A1 (en) * | 2002-09-06 | 2004-07-01 | Vincent Ronfard | Fibrin cell supports and methods of use thereof |
| WO2006008009A2 (en) | 2004-07-23 | 2006-01-26 | Bayer Healthcare Ag | Diagnostics and therapeutics for diseases associated with leucine-rich repeat-containing gpcr 6 (lgr6) |
| US20060154365A1 (en) | 2004-08-30 | 2006-07-13 | Anthony Ratcliffe | Cultured three dimensional tissues and uses thereof |
| US8053559B2 (en) | 2005-10-27 | 2011-11-08 | Coloplast A/S | Biodegradable scaffold with ECM material |
| US20100328320A1 (en) | 2006-07-13 | 2010-12-30 | Kerstna Juergen | Medical information management in a patient information hub system |
| US8366723B2 (en) | 2006-08-03 | 2013-02-05 | Rassman Licensing, Llc | Hair harvesting device and method with localized subsurface dermal fluid insertion |
| WO2008031767A1 (en) | 2006-09-12 | 2008-03-20 | Dkfz Deutsches Krebsforschungszentrum, Stiftung Des Öffentlichen Rechts | Cell culture of keratinocytes under non-differentiating conditions |
| EP2412800A1 (en) | 2010-07-29 | 2012-02-01 | Koninklijke Nederlandse Akademie van Wetenschappen | Liver organoid, uses thereof and culture method for obtaining them |
| GB201111244D0 (en) | 2011-06-30 | 2011-08-17 | Konink Nl Akademie Van Wetenschappen Knaw | Culture media for stem cells |
| US9752124B2 (en) | 2009-02-03 | 2017-09-05 | Koninklijke Nederlandse Akademie Van Wetenschappen | Culture medium for epithelial stem cells and organoids comprising the stem cells |
| FI20095355A0 (fi) | 2009-04-01 | 2009-04-01 | Helsingin Yliopisto | Regeneroituva aktiivinen matriisi ja sen käytöt |
| JP2012531185A (ja) | 2009-06-25 | 2012-12-10 | 株式会社 資生堂 | Ａｆｆ‐４を指標とした抗白髪剤のスクリーニング方法 |
| US20110130711A1 (en) | 2009-11-19 | 2011-06-02 | Follica, Inc. | Hair growth treatment |
| US20130101564A1 (en) | 2010-06-30 | 2013-04-25 | Jinxi Chen | Method for preparing dermis tissue cells aggregation and uses thereof |
| GB201106395D0 (en) | 2011-04-14 | 2011-06-01 | Hubrecht Inst | Compounds |
| JP6215216B2 (ja) | 2011-10-27 | 2017-10-18 | ウニヴェルジテート ライプチッヒ | 毛包外毛根鞘からメラノサイトを誘導する方法および移植のための調製 |
| JP6186997B2 (ja) | 2012-08-07 | 2017-08-30 | 日油株式会社 | 塗布型帯電防止剤 |
| US9655930B2 (en) | 2012-10-01 | 2017-05-23 | Aderans Research Institute, Inc. | Compositions and methods for producing reconstituted skin |
| US20140106447A1 (en) | 2012-10-12 | 2014-04-17 | Mimedx Group, Inc. | Compositions and methods for recruiting stem cells |
| BR112015023261A2 (pt) | 2013-03-14 | 2017-07-18 | Massachusetts Inst Technology | composições e métodos para expansão e cultura de células-tronco epiteliais |
| US9592257B2 (en) | 2013-10-11 | 2017-03-14 | MWV Cell, LLC | Complete human skin organ generated from culture-expanded cells |
| CN103550828B (zh) * | 2013-10-17 | 2016-01-27 | 中国科学院动物研究所 | 一种基于毛囊干细胞和硅凝胶敷料的皮肤重建方法 |
| TWI548413B (zh) | 2014-11-07 | 2016-09-11 | 國立臺灣大學 | 誘導毛囊新生的皮膚萃取物、組合物及其用途 |
-
2015
- 2015-11-30 US US14/954,335 patent/US10926001B2/en active Active
- 2015-12-01 NZ NZ733433A patent/NZ733433A/en unknown
- 2015-12-01 HK HK18104680.7A patent/HK1250515A1/zh unknown
- 2015-12-01 CN CN201580075326.3A patent/CN107250348B/zh active Active
- 2015-12-01 KR KR1020217010934A patent/KR20210043024A/ko not_active Ceased
- 2015-12-01 SG SG10201914058QA patent/SG10201914058QA/en unknown
- 2015-12-01 BR BR112017011808-4A patent/BR112017011808A2/en not_active Application Discontinuation
- 2015-12-01 WO PCT/US2015/063114 patent/WO2016089825A1/en not_active Ceased
- 2015-12-01 NZ NZ755260A patent/NZ755260A/en unknown
- 2015-12-01 EA EA201791125A patent/EA201791125A1/ru unknown
- 2015-12-01 KR KR1020187036619A patent/KR20180136588A/ko not_active Ceased
- 2015-12-01 KR KR1020187036618A patent/KR20180136587A/ko not_active Ceased
- 2015-12-01 KR KR1020177017887A patent/KR20170098844A/ko not_active Ceased
- 2015-12-01 SG SG11201704502RA patent/SG11201704502RA/en unknown
- 2015-12-01 MX MX2017007243A patent/MX2017007243A/es unknown
- 2015-12-01 EP EP15865131.5A patent/EP3227431B1/en active Active
- 2015-12-01 JP JP2017530217A patent/JP6791854B2/ja active Active
- 2015-12-01 CA CA2969707A patent/CA2969707C/en active Active
- 2015-12-01 KR KR1020197028100A patent/KR20190111167A/ko not_active Ceased
- 2015-12-01 MY MYPI2017701990A patent/MY184931A/en unknown
- 2015-12-01 CR CR20170296A patent/CR20170296A/es unknown
- 2015-12-01 EP EP24181160.3A patent/EP4438128A3/en active Pending
- 2015-12-01 AU AU2015355187A patent/AU2015355187C1/en active Active
- 2015-12-01 GB GB201902819A patent/GB2569056B/en active Active
- 2015-12-01 GB GB1710646.9A patent/GB2549872A/en not_active Withdrawn
-
2017
- 2017-05-31 PH PH12017501009A patent/PH12017501009B1/en unknown
- 2017-06-01 IL IL252613A patent/IL252613B/en unknown
- 2017-06-05 MX MX2023001655A patent/MX2023001655A/es unknown
- 2017-06-07 ZA ZA2017/03907A patent/ZA201703907B/en unknown
- 2017-06-30 CO CONC2017/0006640A patent/CO2017006640A2/es unknown
- 2017-07-14 US US15/650,659 patent/US11266765B2/en active Active
- 2017-07-14 US US15/650,656 patent/US20180154043A1/en not_active Abandoned
-
2018
- 2018-10-19 US US16/165,169 patent/US11000629B2/en active Active
-
2019
- 2019-01-16 JP JP2019004921A patent/JP2019088299A/ja active Pending
- 2019-10-02 AU AU2019240603A patent/AU2019240603B2/en active Active
-
2020
- 2020-07-30 JP JP2020129610A patent/JP2020182880A/ja active Pending
-
2021
- 2021-05-21 US US17/326,734 patent/US11338060B2/en active Active
- 2021-10-21 IL IL287488A patent/IL287488B2/en unknown
-
2022
- 2022-04-19 US US17/723,748 patent/US11596714B2/en active Active
-
2023
- 2023-02-03 US US18/164,308 patent/US12465669B2/en active Active
- 2023-05-08 AU AU2023202857A patent/AU2023202857A1/en not_active Abandoned
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CO2017006640A2 (es) | Metodos para el desarrollo y uso de unidades de micro-agregado de funcion celular polarizada en aplicaciones de tejido usando lgr4, lgr5 y lgr 6 que expresan celulas madre epiteliales | |
| CY1125326T1 (el) | Προαιρετικως συντηγμενα ετεροκυκλυλο- υποκατεστημενα παραγωγα πυριμιδινης χρησιμα για τη θεραπευτικη αγωγη φλεγμονωδων, μεταβολικων, ογκολογικων και αυτοανοσων ασθενειων. | |
| MX2015000990A (es) | Analogos del glucagon. | |
| MX2020005634A (es) | Composiciones y metodos para mejorar los linfocitos infiltrantes de tumor para terapia celular adoptiva. | |
| MX387259B (es) | Agonistas receptores de glp-1 y usos de los mismos | |
| MX2015017865A (es) | Compuestos de pirimidinodiona contra estados cardiacos. | |
| MX2017001008A (es) | Tratamiento de cancer utilizando un receptor quimerico de antigeno cd33. | |
| MX2015014408A (es) | Co-agonista de peptido similar a glucagon tipo 1 (glp-1) receptor de glucagon de larga duracion, estables para uso medico. | |
| AR104984A1 (es) | Compuestos selectivos para pyy y sus usos | |
| MX2021012539A (es) | Antagonistas de receptor del factor de liberacion de corticotropina (crf1) para el tratamiento de hiperplasia adrenal congenita. | |
| MX384175B (es) | Métodos para seleccionar una línea de células t y el donador de la misma para terapia celular adoptiva. | |
| MX2020004837A (es) | Inhibidores de la vía de adenosina para el tratamiento del cáncer. | |
| CO2020006443A2 (es) | Métodos y composiciones para la dosificación de células t con receptor de antígeno quimérico alogénicas | |
| PE20181346A1 (es) | Compuestos de imidazo[4,5-c]quinolin-2-ona y su uso en el tratamiento del cancer | |
| MX2016010998A (es) | Terapia celular adoptiva que usa un agonista de receptor huérfano gamma relacionado con receptor de ácido retinoico y métodos terapéuticos relacionados. | |
| CL2020000019A1 (es) | Agentes de iarn para la inhibición de la expresión de alfa-enac y métodos de uso. | |
| GT201700194A (es) | Formulación de combinación de tesofensina y betabloqueante | |
| CL2015001446A1 (es) | Procedimiento de preparación de albumina humana con nivel de oxigeno disuelto reducido. | |
| UY36150A (es) | Derivados de naftiridinadiona | |
| MX386476B (es) | Agente estimulador del receptor 1b de 5-hidroxitriptamina para mejorar el potencial de injerto in vivo. | |
| ECSP16086232A (es) | (r) -pirlindole y sus sales farmacéuticamente aceptables para uso en medicina | |
| EA201691596A1 (ru) | Составы гепарина для наружного применения | |
| CL2009001221A1 (es) | Uso de un androgeno y/o un modulador selectivo del receptor de androgeno para preparar un medicamento para el tratamiento de la insuficiencia cardiaca o para retardar o detener el avance de la insuficiencia cardiaca en un sujeto humano de sexo femenino. | |
| AR101582A1 (es) | Tratamiento de tejido mamario con óxido nítrico | |
| BR112017006918A2 (pt) | formulações nanoestruturadas para liberação de silibinina e outros ingredientes ativos para o tratamento de doenças oculares |