MX2017004542A - Inmunomoduladores. - Google Patents
Inmunomoduladores.Info
- Publication number
- MX2017004542A MX2017004542A MX2017004542A MX2017004542A MX2017004542A MX 2017004542 A MX2017004542 A MX 2017004542A MX 2017004542 A MX2017004542 A MX 2017004542A MX 2017004542 A MX2017004542 A MX 2017004542A MX 2017004542 A MX2017004542 A MX 2017004542A
- Authority
- MX
- Mexico
- Prior art keywords
- protein
- immunomodulators
- inhibit
- improvement
- useful
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/50—Cyclic peptides containing at least one abnormal peptide link
- C07K7/54—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
- C07K7/56—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation not occurring through 2,4-diamino-butanoic acid
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/64—Cyclic peptides containing only normal peptide links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/10—Peptides having 12 to 20 amino acids
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
- G01N2333/70503—Immunoglobulin superfamily, e.g. VCAMs, PECAM, LFA-3
- G01N2333/70532—B7 molecules, e.g. CD80, CD86
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
- G01N2500/02—Screening involving studying the effect of compounds C on the interaction between interacting molecules A and B (e.g. A = enzyme and B = substrate for A, or A = receptor and B = ligand for the receptor)
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/26—Infectious diseases, e.g. generalised sepsis
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Gastroenterology & Hepatology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462062240P | 2014-10-10 | 2014-10-10 | |
| PCT/US2015/054407 WO2016057624A1 (en) | 2014-10-10 | 2015-10-07 | Immunomodulators |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2017004542A true MX2017004542A (es) | 2017-06-23 |
Family
ID=54330101
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2017004542A MX2017004542A (es) | 2014-10-10 | 2015-10-07 | Inmunomoduladores. |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US9732119B2 (enExample) |
| EP (1) | EP3204403B1 (enExample) |
| JP (1) | JP6718439B2 (enExample) |
| KR (1) | KR102538436B1 (enExample) |
| CN (1) | CN107001424B (enExample) |
| AR (1) | AR102350A1 (enExample) |
| AU (1) | AU2015328136A1 (enExample) |
| BR (1) | BR112017006980A2 (enExample) |
| CA (1) | CA2963930A1 (enExample) |
| CL (1) | CL2017000855A1 (enExample) |
| CO (1) | CO2017004535A2 (enExample) |
| EA (1) | EA201790695A1 (enExample) |
| ES (1) | ES2793018T3 (enExample) |
| IL (1) | IL251589A0 (enExample) |
| MX (1) | MX2017004542A (enExample) |
| PE (1) | PE20170701A1 (enExample) |
| SG (1) | SG11201702792SA (enExample) |
| TW (1) | TW201629088A (enExample) |
| WO (1) | WO2016057624A1 (enExample) |
| ZA (1) | ZA201702484B (enExample) |
Families Citing this family (86)
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| EP2928474B1 (en) | 2012-12-07 | 2018-11-14 | ChemoCentryx, Inc. | Diazole lactams |
| MA40132B1 (fr) | 2014-09-11 | 2019-04-30 | Bristol Myers Squibb Co | Inhibiteurs macrocycliques des interactions protéine/protéine pd-1/pd-l1 et cd80(b7-1)/pd-li |
| US9856292B2 (en) | 2014-11-14 | 2018-01-02 | Bristol-Myers Squibb Company | Immunomodulators |
| US9861680B2 (en) | 2014-12-18 | 2018-01-09 | Bristol-Myers Squibb Company | Immunomodulators |
| US9944678B2 (en) | 2014-12-19 | 2018-04-17 | Bristol-Myers Squibb Company | Immunomodulators |
| AU2016205215B2 (en) | 2015-01-09 | 2021-03-11 | Etubics Corporation | Methods and compositions for combination immunotherapy |
| US20160222060A1 (en) | 2015-02-04 | 2016-08-04 | Bristol-Myers Squibb Company | Immunomodulators |
| US9809625B2 (en) | 2015-03-18 | 2017-11-07 | Bristol-Myers Squibb Company | Immunomodulators |
| US11149087B2 (en) * | 2015-04-20 | 2021-10-19 | Etubics Corporation | Methods and compositions for combination immunotherapy |
| RU2726206C2 (ru) | 2015-05-21 | 2020-07-09 | Кемосентрикс, Инк. | Модуляторы ccr2 |
| US10143746B2 (en) | 2016-03-04 | 2018-12-04 | Bristol-Myers Squibb Company | Immunomodulators |
| US10358463B2 (en) * | 2016-04-05 | 2019-07-23 | Bristol-Myers Squibb Company | Immunomodulators |
| IL261998B2 (en) | 2016-04-07 | 2023-03-01 | Chemocentryx Inc | Reducing your burden by giving ccr1 antagonists in combination with pd-1 inhibitors or pd-l1 inhibitors |
| TWI808055B (zh) | 2016-05-11 | 2023-07-11 | 美商滬亞生物國際有限公司 | Hdac 抑制劑與 pd-1 抑制劑之組合治療 |
| TWI794171B (zh) | 2016-05-11 | 2023-03-01 | 美商滬亞生物國際有限公司 | Ｈｄａｃ抑制劑與ｐｄ-ｌ１抑制劑之組合治療 |
| WO2017201111A1 (en) | 2016-05-19 | 2017-11-23 | Bristol-Myers Squibb Company | Pet-imaging immunomodulators |
| KR20230010826A (ko) | 2016-10-14 | 2023-01-19 | 프리시젼 바이오사이언시스 인코포레이티드 | B형 간염 바이러스 게놈 내의 인식 서열에 대해 특이적인 조작된 메가뉴클레아제 |
| KR102526034B1 (ko) * | 2016-11-07 | 2023-04-25 | 브리스톨-마이어스 스큅 컴퍼니 | 면역조정제 |
| CN106963948A (zh) * | 2017-05-12 | 2017-07-21 | 顾艳宏 | 阿帕替尼与Anti‑PD‑1抗体联用在制备结肠癌药物中的应用 |
| CN110997698B (zh) * | 2017-06-23 | 2023-12-26 | 百时美施贵宝公司 | 充当pd-1拮抗剂的免疫调节剂 |
| EP3687525B1 (en) | 2017-09-25 | 2025-10-29 | ChemoCentryx, Inc. | Combination therapy using a chemokine receptor 2 (ccr2) antagonist and a pd-1/pd-l1 inhibitor |
| EP3692053A1 (en) | 2017-10-03 | 2020-08-12 | Bristol-Myers Squibb Company | Immunomodulators |
| US11203610B2 (en) | 2017-12-20 | 2021-12-21 | Institute Of Organic Chemistry And Biochemistry Ascr, V.V.I. | 2′3′ cyclic dinucleotides with phosphonate bond activating the sting adaptor protein |
| JP7037667B2 (ja) | 2017-12-20 | 2022-03-16 | インスティチュート オブ オーガニック ケミストリー アンド バイオケミストリー エーエスシーアール，ヴイ．ヴイ．アイ． | Ｓｔｉｎｇアダプタータンパク質を活性化するホスホン酸結合を有する３’３’環状ジヌクレオチド |
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| CN112105353B (zh) | 2018-01-08 | 2024-04-19 | 凯莫森特里克斯股份有限公司 | Ccr2拮抗剂治疗实体瘤的方法 |
| JP7050165B2 (ja) | 2018-02-26 | 2022-04-07 | ギリアード サイエンシーズ， インコーポレイテッド | Ｈｂｖ複製阻害剤としての置換ピロリジン化合物 |
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-
2015
- 2015-10-05 US US14/874,886 patent/US9732119B2/en active Active
- 2015-10-07 AU AU2015328136A patent/AU2015328136A1/en not_active Abandoned
- 2015-10-07 JP JP2017519313A patent/JP6718439B2/ja not_active Expired - Fee Related
- 2015-10-07 MX MX2017004542A patent/MX2017004542A/es unknown
- 2015-10-07 SG SG11201702792SA patent/SG11201702792SA/en unknown
- 2015-10-07 CN CN201580066937.1A patent/CN107001424B/zh active Active
- 2015-10-07 PE PE2017000575A patent/PE20170701A1/es unknown
- 2015-10-07 EA EA201790695A patent/EA201790695A1/ru unknown
- 2015-10-07 CA CA2963930A patent/CA2963930A1/en not_active Abandoned
- 2015-10-07 EP EP15781564.8A patent/EP3204403B1/en active Active
- 2015-10-07 ES ES15781564T patent/ES2793018T3/es active Active
- 2015-10-07 KR KR1020177012216A patent/KR102538436B1/ko active Active
- 2015-10-07 WO PCT/US2015/054407 patent/WO2016057624A1/en not_active Ceased
- 2015-10-07 BR BR112017006980A patent/BR112017006980A2/pt not_active Application Discontinuation
- 2015-10-08 TW TW104133278A patent/TW201629088A/zh unknown
- 2015-10-09 AR ARP150103279A patent/AR102350A1/es unknown
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2017
- 2017-04-05 IL IL251589A patent/IL251589A0/en unknown
- 2017-04-07 CL CL2017000855A patent/CL2017000855A1/es unknown
- 2017-04-07 ZA ZA2017/02484A patent/ZA201702484B/en unknown
- 2017-05-05 CO CONC2017/0004535A patent/CO2017004535A2/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| KR102538436B1 (ko) | 2023-05-30 |
| WO2016057624A1 (en) | 2016-04-14 |
| SG11201702792SA (en) | 2017-05-30 |
| CA2963930A1 (en) | 2016-04-14 |
| KR20170064548A (ko) | 2017-06-09 |
| ES2793018T3 (es) | 2020-11-12 |
| EP3204403B1 (en) | 2020-04-08 |
| TW201629088A (zh) | 2016-08-16 |
| CN107001424B (zh) | 2021-03-05 |
| JP2017536344A (ja) | 2017-12-07 |
| AR102350A1 (es) | 2017-02-22 |
| EA201790695A1 (ru) | 2017-08-31 |
| CL2017000855A1 (es) | 2017-12-11 |
| CN107001424A (zh) | 2017-08-01 |
| EP3204403A1 (en) | 2017-08-16 |
| CO2017004535A2 (es) | 2017-08-31 |
| BR112017006980A2 (pt) | 2017-12-12 |
| US20160102122A1 (en) | 2016-04-14 |
| AU2015328136A1 (en) | 2017-05-25 |
| JP6718439B2 (ja) | 2020-07-08 |
| IL251589A0 (en) | 2017-06-29 |
| US9732119B2 (en) | 2017-08-15 |
| PE20170701A1 (es) | 2017-06-05 |
| ZA201702484B (en) | 2019-06-26 |
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