MX2016010031A - Composiciones para producir jarabes de glucosa. - Google Patents
Composiciones para producir jarabes de glucosa.Info
- Publication number
- MX2016010031A MX2016010031A MX2016010031A MX2016010031A MX2016010031A MX 2016010031 A MX2016010031 A MX 2016010031A MX 2016010031 A MX2016010031 A MX 2016010031A MX 2016010031 A MX2016010031 A MX 2016010031A MX 2016010031 A MX2016010031 A MX 2016010031A
- Authority
- MX
- Mexico
- Prior art keywords
- glucose syrup
- compositions
- produce glucose
- pululanase
- gds
- Prior art date
Links
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 title abstract 2
- 239000008103 glucose Substances 0.000 title abstract 2
- 239000006188 syrup Substances 0.000 title abstract 2
- 235000020357 syrup Nutrition 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 title 1
- 229920002472 Starch Polymers 0.000 abstract 3
- 102000004139 alpha-Amylases Human genes 0.000 abstract 3
- 108090000637 alpha-Amylases Proteins 0.000 abstract 3
- 229940024171 alpha-amylase Drugs 0.000 abstract 3
- 239000008107 starch Substances 0.000 abstract 3
- 235000019698 starch Nutrition 0.000 abstract 3
- 108010073178 Glucan 1,4-alpha-Glucosidase Proteins 0.000 abstract 1
- 102100022624 Glucoamylase Human genes 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L29/00—Foods or foodstuffs containing additives; Preparation or treatment thereof
- A23L29/30—Foods or foodstuffs containing additives; Preparation or treatment thereof containing carbohydrate syrups; containing sugars; containing sugar alcohols, e.g. xylitol; containing starch hydrolysates, e.g. dextrin
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/14—Preparation of compounds containing saccharide radicals produced by the action of a carbohydrase (EC 3.2.x), e.g. by alpha-amylase, e.g. by cellulase, hemicellulase
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L29/00—Foods or foodstuffs containing additives; Preparation or treatment thereof
- A23L29/30—Foods or foodstuffs containing additives; Preparation or treatment thereof containing carbohydrate syrups; containing sugars; containing sugar alcohols, e.g. xylitol; containing starch hydrolysates, e.g. dextrin
- A23L29/35—Degradation products of starch, e.g. hydrolysates, dextrins; Enzymatically modified starches
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
- C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
- C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
- C12N9/2405—Glucanases
- C12N9/2408—Glucanases acting on alpha -1,4-glucosidic bonds
- C12N9/2411—Amylases
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
- C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
- C12N9/2405—Glucanases
- C12N9/2408—Glucanases acting on alpha -1,4-glucosidic bonds
- C12N9/2411—Amylases
- C12N9/2428—Glucan 1,4-alpha-glucosidase (3.2.1.3), i.e. glucoamylase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
- C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
- C12N9/2405—Glucanases
- C12N9/2451—Glucanases acting on alpha-1,6-glucosidic bonds
- C12N9/2457—Pullulanase (3.2.1.41)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/02—Monosaccharides
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
- C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
- C12Y302/01001—Alpha-amylase (3.2.1.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
- C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
- C12Y302/01003—Glucan 1,4-alpha-glucosidase (3.2.1.3), i.e. glucoamylase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
- C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
- C12Y302/01041—Pullulanase (3.2.1.41)
-
- C—CHEMISTRY; METALLURGY
- C13—SUGAR INDUSTRY
- C13K—SACCHARIDES OBTAINED FROM NATURAL SOURCES OR BY HYDROLYSIS OF NATURALLY OCCURRING DISACCHARIDES, OLIGOSACCHARIDES OR POLYSACCHARIDES
- C13K1/00—Glucose; Glucose-containing syrups
- C13K1/06—Glucose; Glucose-containing syrups obtained by saccharification of starch or raw materials containing starch
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
- Y02E50/00—Technologies for the production of fuel of non-fossil origin
- Y02E50/10—Biofuels, e.g. bio-diesel
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nutrition Science (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Emergency Medicine (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
- Jellies, Jams, And Syrups (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
La presente invención se refiere a un método para preparar jarabe de glucosa a partir de almidón licuado que comprende, (a) poner en contacto el almidón licuado con una glucoamilasa, una pululanasa, y, opcionalmente una alfa-amilasa en la que la relación de la dosis de pululanasa expresada como NPUN/gDS, a la dosis de alfa amilasa expresada como AFAU/gDS es al menos de 60, particularmente al menos 75, particularmente al menos 100, más particularmente al menos 150, más particularmente al menos 200, más particularmente al menos 250, más particularmente al menos 300, más particularmente al menos 400, más particularmente al menos 500, más particularmente al menos 600, más particularmente al menos 800 o si no está presente alfa-amilasa, la pululanasa está presente en una dosis de al menos 0.5, particularmente al menos 0.75, particularmente al menos 1.0, particularmente al menos 1.5 de NPUN/gDS, y (b) sacarificar el almidón licuado.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP14154239 | 2014-02-07 | ||
| EP14195687 | 2014-12-01 | ||
| PCT/EP2015/052545 WO2015118123A1 (en) | 2014-02-07 | 2015-02-06 | Compositions for producing glucose syrups |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MX2016010031A true MX2016010031A (es) | 2016-11-15 |
| MX385596B MX385596B (es) | 2025-03-18 |
Family
ID=52464388
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2016010031A MX385596B (es) | 2014-02-07 | 2015-02-06 | Composiciones para producir jarabes de glucosa. |
Country Status (10)
| Country | Link |
|---|---|
| US (3) | US10337041B2 (es) |
| EP (2) | EP3102051B1 (es) |
| JP (1) | JP6591993B2 (es) |
| CN (1) | CN105960176A (es) |
| BR (1) | BR112016018075B1 (es) |
| CA (1) | CA2937818C (es) |
| HU (1) | HUE064397T2 (es) |
| MX (1) | MX385596B (es) |
| RU (2) | RU2019134734A (es) |
| WO (1) | WO2015118123A1 (es) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR3091703B1 (fr) | 2019-01-11 | 2021-02-12 | Fermentalg | Procédé d’extraction de phycocyanines |
| FR3091640B1 (fr) | 2019-01-11 | 2021-06-11 | Fermentalg | Procédé de purification de phycocyanines |
| FR3092586A1 (fr) | 2019-02-08 | 2020-08-14 | Fermentalg | Procédé optimisé d’exploitation industrielle d’algues rouges unicellulaires |
| CA3257053A1 (en) | 2022-05-14 | 2023-11-23 | Novozymes A/S | COMPOSITIONS AND METHODS FOR THE PREVENTION, TREATMENT, SUPPRESSION AND/OR ELIMINATION OF PHYTOPATHOGENIC INFESTATIONS AND INFECTIONS |
Family Cites Families (46)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5534046A (en) | 1978-09-01 | 1980-03-10 | Cpc International Inc | Novel glucoamyrase having excellent heat resistance and production |
| US4335208A (en) | 1980-03-11 | 1982-06-15 | Novo Industri A/S | Saccharification of starch hydrolysates |
| NO840200L (no) | 1983-01-28 | 1984-07-30 | Cefus Corp | Glukoamylase cdna. |
| US4587215A (en) | 1984-06-25 | 1986-05-06 | Uop Inc. | Highly thermostable amyloglucosidase |
| JPS62126989A (ja) | 1985-11-26 | 1987-06-09 | Godo Shiyusei Kk | コルテイシウム属担子菌の生産する酵素を用いた澱粉質の無蒸煮糖化法 |
| WO1989001969A1 (en) | 1987-09-04 | 1989-03-09 | Novo-Nordisk A/S | Process for the production of protein products in aspergillus and promoters for use in aspergillus |
| US5162210A (en) | 1990-06-29 | 1992-11-10 | Iowa State University Research Foundation | Process for enzymatic hydrolysis of starch to glucose |
| DE69325981T2 (de) | 1992-12-28 | 2000-02-03 | Genencor International, Inc. | Pullulanase, Mikroorganismen die sie produzieren, Verfahren zur Herstellung und ihre Anwendung |
| DK2199378T3 (da) | 1995-02-03 | 2012-10-29 | Novozymes As | alfa-amylase mutanter |
| EP0904360B1 (en) | 1996-04-30 | 2013-07-31 | Novozymes A/S | alpha-AMYLASE MUTANTS |
| CN1238009A (zh) * | 1996-07-24 | 1999-12-08 | 衣阿华州立大学研究基金会股份有限公司 | 提高葡糖淀粉酶pH最适点、底物专一性和热稳定性的蛋白质工程方法 |
| EP1032654B1 (en) | 1997-11-26 | 2009-01-21 | Novozymes A/S | Thermostable glucoamylase |
| KR100764528B1 (ko) | 1998-07-15 | 2007-10-09 | 노보자임스 에이/에스 | 글루코아밀라제 변이체 |
| JP2003504046A (ja) | 1999-07-09 | 2003-02-04 | ノボザイムス アクティーゼルスカブ | グルコアミラーゼ変異体 |
| US7244597B2 (en) * | 2000-11-10 | 2007-07-17 | Novozymes A/S | Secondary liquefaction in ethanol production |
| WO2004055178A1 (en) | 2002-12-17 | 2004-07-01 | Novozymes A/S | Thermostable alpha-amylases |
| ES2517245T3 (es) | 2003-06-25 | 2014-11-03 | Novozymes A/S | Enzimas para el tratamiento de almidón |
| US7618795B2 (en) * | 2003-06-25 | 2009-11-17 | Novozymes A/S | Starch process |
| WO2005003311A2 (en) | 2003-06-25 | 2005-01-13 | Novozymes A/S | Enzymes for starch processing |
| JP2007527726A (ja) * | 2004-03-08 | 2007-10-04 | シンジェンタ パーティシペーションズ アクチェンゲゼルシャフト | 自己プロセシング植物および植物部分 |
| US20080032373A1 (en) * | 2004-05-13 | 2008-02-07 | Novozymes North America, Inc. | Process Of Producing A Fermentation Product |
| WO2006060062A2 (en) * | 2004-11-30 | 2006-06-08 | Genencor International, Inc. | Trichoderma reesei glucoamylase and homologs thereof |
| DK1831385T3 (en) | 2004-12-22 | 2015-07-13 | Novozymes North America Inc | Enzymes for starch processing |
| WO2007144393A1 (en) | 2006-06-15 | 2007-12-21 | Novozymes, Inc. | Mashing process |
| US9447397B2 (en) | 2006-10-10 | 2016-09-20 | Danisco Us Inc. | Glucoamylase variants with altered properties |
| CN101049133B (zh) * | 2007-04-26 | 2011-07-06 | 华南理工大学 | 小麦b淀粉多酶法制取发酵用含氮糖浆的方法 |
| ES2504983T3 (es) | 2007-10-09 | 2014-10-09 | Danisco Us Inc. | Variantes de glucoamilasa |
| PL2222830T3 (pl) | 2007-12-12 | 2015-12-31 | Novozymes As | Sposób zacierania |
| US11041139B2 (en) * | 2007-12-12 | 2021-06-22 | Novozymes A/S | Brewing process |
| WO2011022465A1 (en) | 2009-08-19 | 2011-02-24 | Danisco Us Inc. | Combinatorial variants of glucoamylase with improved specific activity and/or thermostability |
| CN107299123A (zh) | 2009-08-19 | 2017-10-27 | 杜邦营养生物科学有限公司 | 葡糖淀粉酶的变体 |
| ES2534098T3 (es) | 2009-11-30 | 2015-04-17 | Novozymes A/S | Polipéptidos que tienen actividad de glucoamilasa y polinucleótidos que codifican los mismos |
| CA2782036C (en) | 2009-12-01 | 2019-01-15 | Novozymes A/S | Polypeptides having glucoamylase activity and polynucleotides encoding same |
| CA2795806C (en) | 2010-04-14 | 2019-01-08 | Novozymes A/S | Polypeptides having glucoamylase activity and polynucleotides encoding same |
| CN103298932B (zh) | 2010-11-08 | 2016-08-10 | 诺维信公司 | 具有葡糖淀粉酶活性的多肽和编码该多肽的多核苷酸 |
| KR101188113B1 (ko) * | 2010-12-23 | 2012-10-05 | 대상 주식회사 | 유동성이 향상된 쌀엿 제조방법 |
| JP5928089B2 (ja) * | 2011-04-04 | 2016-06-01 | 国立大学法人弘前大学 | イソマルターゼ |
| CN103930543B (zh) | 2011-09-06 | 2020-11-27 | 诺维信公司 | 葡糖淀粉酶变体和编码它们的多核苷酸 |
| CA2861678C (en) | 2011-10-11 | 2021-02-16 | Novozymes North America, Inc. | Processes for producing fermentation products |
| FR2989892B1 (fr) * | 2012-04-26 | 2014-05-16 | Oreal | Composition cosmetique comprenant un oligosaccharide phosphoryle et un polysaccharide |
| MX2015002099A (es) * | 2012-08-22 | 2015-05-11 | Dupont Nutrition Biosci Aps | Variantes que tienen actividad glucoamilasa. |
| EP2992092B1 (en) * | 2013-04-30 | 2018-04-04 | Novozymes A/S | Glucoamylase variants and polynucleotides encoding same |
| US10450551B2 (en) * | 2013-08-30 | 2019-10-22 | Novozymes A/S | Enzyme composition and uses thereof |
| DK3415624T3 (da) * | 2014-01-22 | 2021-11-08 | Novozymes As | Pullulanasevarianter og polynukleotider, som koder for dem |
| CN106795505A (zh) * | 2014-10-23 | 2017-05-31 | 诺维信公司 | 葡糖淀粉酶变体和编码它们的多核苷酸 |
| CA2967710A1 (en) * | 2014-12-01 | 2016-06-09 | Novozymes A/S | Improved production of glucose syrups |
-
2015
- 2015-02-06 BR BR112016018075-5A patent/BR112016018075B1/pt active IP Right Grant
- 2015-02-06 RU RU2019134734A patent/RU2019134734A/ru unknown
- 2015-02-06 US US15/116,006 patent/US10337041B2/en active Active
- 2015-02-06 RU RU2016135029A patent/RU2706297C2/ru active
- 2015-02-06 MX MX2016010031A patent/MX385596B/es unknown
- 2015-02-06 EP EP15703567.6A patent/EP3102051B1/en active Active
- 2015-02-06 EP EP20163541.4A patent/EP3712240B1/en active Active
- 2015-02-06 HU HUE20163541A patent/HUE064397T2/hu unknown
- 2015-02-06 JP JP2016550206A patent/JP6591993B2/ja active Active
- 2015-02-06 CN CN201580007414.XA patent/CN105960176A/zh active Pending
- 2015-02-06 CA CA2937818A patent/CA2937818C/en active Active
- 2015-02-06 WO PCT/EP2015/052545 patent/WO2015118123A1/en not_active Ceased
-
2019
- 2019-05-06 US US16/403,919 patent/US11136607B2/en active Active
-
2021
- 2021-09-02 US US17/465,098 patent/US11667938B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| US20210395791A1 (en) | 2021-12-23 |
| RU2706297C2 (ru) | 2019-11-15 |
| HUE064397T2 (hu) | 2024-03-28 |
| US11667938B2 (en) | 2023-06-06 |
| CA2937818A1 (en) | 2015-08-13 |
| RU2016135029A3 (es) | 2018-10-16 |
| RU2019134734A (ru) | 2019-11-18 |
| CN105960176A (zh) | 2016-09-21 |
| RU2016135029A (ru) | 2018-03-13 |
| MX385596B (es) | 2025-03-18 |
| US10337041B2 (en) | 2019-07-02 |
| EP3712240B1 (en) | 2023-09-27 |
| EP3102051A1 (en) | 2016-12-14 |
| US20190256878A1 (en) | 2019-08-22 |
| JP6591993B2 (ja) | 2019-10-16 |
| EP3712240A1 (en) | 2020-09-23 |
| CA2937818C (en) | 2023-08-01 |
| BR112016018075A2 (pt) | 2018-02-20 |
| US20170159090A1 (en) | 2017-06-08 |
| BR112016018075B1 (pt) | 2022-01-18 |
| WO2015118123A1 (en) | 2015-08-13 |
| JP2017505129A (ja) | 2017-02-16 |
| EP3102051B1 (en) | 2020-04-08 |
| US11136607B2 (en) | 2021-10-05 |
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