MX2015017655A - Modulador de receptores de estrogeno y uso del mismo. - Google Patents
Modulador de receptores de estrogeno y uso del mismo.Info
- Publication number
- MX2015017655A MX2015017655A MX2015017655A MX2015017655A MX2015017655A MX 2015017655 A MX2015017655 A MX 2015017655A MX 2015017655 A MX2015017655 A MX 2015017655A MX 2015017655 A MX2015017655 A MX 2015017655A MX 2015017655 A MX2015017655 A MX 2015017655A
- Authority
- MX
- Mexico
- Prior art keywords
- estrogen receptor
- receptor modulator
- compounds
- receptor modulators
- estrogen
- Prior art date
Links
- 239000002834 estrogen receptor modulator Substances 0.000 title abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 3
- 230000001419 dependent effect Effects 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 102000015694 estrogen receptors Human genes 0.000 abstract 1
- 108010038795 estrogen receptors Proteins 0.000 abstract 1
- 230000001404 mediated effect Effects 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/397—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having four-membered rings, e.g. azetidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/38—Cellulose; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4866—Organic macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/32—Antioestrogens
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Dermatology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Inorganic Chemistry (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Diabetes (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicinal Preparation (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361836901P | 2013-06-19 | 2013-06-19 | |
| US201461952430P | 2014-03-13 | 2014-03-13 | |
| PCT/US2014/043040 WO2014205138A1 (en) | 2013-06-19 | 2014-06-18 | Estrogen receptor modulator and uses thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2015017655A true MX2015017655A (es) | 2016-04-15 |
Family
ID=52105249
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2015017655A MX2015017655A (es) | 2013-06-19 | 2014-06-18 | Modulador de receptores de estrogeno y uso del mismo. |
Country Status (19)
| Country | Link |
|---|---|
| US (2) | US9873684B2 (https=) |
| EP (1) | EP3010501B1 (https=) |
| JP (2) | JP6576916B2 (https=) |
| KR (1) | KR20160021277A (https=) |
| CN (1) | CN105324115B (https=) |
| AU (1) | AU2014281511A1 (https=) |
| BR (1) | BR112015031903A8 (https=) |
| CA (1) | CA2912853A1 (https=) |
| CL (1) | CL2015003456A1 (https=) |
| CR (1) | CR20150664A (https=) |
| EA (1) | EA031077B1 (https=) |
| IL (1) | IL242611B (https=) |
| MX (1) | MX2015017655A (https=) |
| PE (1) | PE20160157A1 (https=) |
| PH (1) | PH12015502621A1 (https=) |
| SG (1) | SG11201509508YA (https=) |
| TW (1) | TW201501710A (https=) |
| UA (1) | UA117249C2 (https=) |
| WO (1) | WO2014205138A1 (https=) |
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|---|---|---|---|---|
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| CA2915534A1 (en) | 2013-06-19 | 2014-12-24 | Seragon Pharmaceuticals, Inc. | Azetidine estrogen receptor modulators and uses thereof |
| EA031077B1 (ru) * | 2013-06-19 | 2018-11-30 | Серагон Фармасьютикалз, Инк. | Модулятор рецептора эстрогена и его применения |
| EP2862880A1 (en) | 2013-10-16 | 2015-04-22 | Solvay Acetow GmbH | Acylation process |
| WO2015136016A2 (en) * | 2014-03-13 | 2015-09-17 | F. Hoffmann-La Roche Ag | Therapeutic combinations with estrogen receptor modulators |
| SG11201607339VA (en) | 2014-03-13 | 2016-10-28 | Hoffmann La Roche | Methods and compositions for modulating estrogen receptor mutants |
| ES2748029T3 (es) | 2014-03-13 | 2020-03-12 | Univ Indiana Res & Tech Corp | Moduladores alostéricos de proteína núcleo de hepatitis B |
| TWI874834B (zh) | 2014-12-18 | 2025-03-01 | 瑞士商赫孚孟拉羅股份公司 | 四氫-吡啶并[3,4-b]吲哚雌激素受體調節劑及其用途 |
| WO2016097071A1 (en) | 2014-12-18 | 2016-06-23 | F. Hoffmann-La Roche Ag | Estrogen receptor modulators and uses thereof |
| US20160175284A1 (en) * | 2014-12-18 | 2016-06-23 | Genentech, Inc. | Estrogen receptor modulators and uses thereof |
| MD3302471T2 (ro) | 2015-05-29 | 2021-12-31 | Eisai R&D Man Co Ltd | Compuși de alchenă tetrasubstituiți și utilizarea acestora |
| WO2017024318A1 (en) | 2015-08-06 | 2017-02-09 | Dana-Farber Cancer Institute, Inc. | Targeted protein degradation to attenuate adoptive t-cell therapy associated adverse inflammatory responses |
| TWI721016B (zh) | 2015-09-15 | 2021-03-11 | 美商艾森伯利生物科學公司 | B型肝炎核心蛋白質調節劑 |
| KR20240142622A (ko) * | 2015-10-01 | 2024-09-30 | 올레마 파마슈티컬스 인코포레이티드 | 테트라히드로-1H-피리도[3,4-b]인돌 항에스트로겐 약물 |
| WO2017072792A1 (en) | 2015-10-27 | 2017-05-04 | Sun Pharma Advanced Research Company Limited | Novel heterocyclic antiestrogens |
| LT3386500T (lt) | 2015-12-09 | 2022-12-27 | The Board Of Trustees Of The University Of Illinois | Selektyvūs estrogenų receptorių slopintojai benzotiofeno pagrindu |
| WO2017182493A1 (en) | 2016-04-20 | 2017-10-26 | Astrazeneca Ab | Indazole derivatives for use in down-regulation of the estrogen receptor for the treatment of cancer |
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| EP3454856B1 (en) | 2016-05-10 | 2024-09-11 | C4 Therapeutics, Inc. | Heterocyclic degronimers for target protein degradation |
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| TWI808055B (zh) | 2016-05-11 | 2023-07-11 | 美商滬亞生物國際有限公司 | Hdac 抑制劑與 pd-1 抑制劑之組合治療 |
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-
2014
- 2014-06-18 EA EA201592214A patent/EA031077B1/ru not_active IP Right Cessation
- 2014-06-18 KR KR1020167001338A patent/KR20160021277A/ko not_active Withdrawn
- 2014-06-18 CA CA2912853A patent/CA2912853A1/en not_active Abandoned
- 2014-06-18 SG SG11201509508YA patent/SG11201509508YA/en unknown
- 2014-06-18 MX MX2015017655A patent/MX2015017655A/es unknown
- 2014-06-18 BR BR112015031903A patent/BR112015031903A8/pt not_active Application Discontinuation
- 2014-06-18 JP JP2016521557A patent/JP6576916B2/ja active Active
- 2014-06-18 WO PCT/US2014/043040 patent/WO2014205138A1/en not_active Ceased
- 2014-06-18 EP EP14812952.1A patent/EP3010501B1/en active Active
- 2014-06-18 AU AU2014281511A patent/AU2014281511A1/en not_active Abandoned
- 2014-06-18 PE PE2015002634A patent/PE20160157A1/es unknown
- 2014-06-18 CN CN201480035316.2A patent/CN105324115B/zh active Active
- 2014-06-18 UA UAA201600246A patent/UA117249C2/uk unknown
- 2014-06-19 TW TW103121277A patent/TW201501710A/zh unknown
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2015
- 2015-11-16 IL IL242611A patent/IL242611B/en not_active IP Right Cessation
- 2015-11-24 PH PH12015502621A patent/PH12015502621A1/en unknown
- 2015-11-24 CL CL2015003456A patent/CL2015003456A1/es unknown
- 2015-12-09 US US14/963,658 patent/US9873684B2/en active Active
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2017
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2019
- 2019-03-13 JP JP2019045520A patent/JP2019142871A/ja active Pending
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| Publication number | Publication date |
|---|---|
| AU2014281511A1 (en) | 2015-12-03 |
| US10227334B2 (en) | 2019-03-12 |
| BR112015031903A2 (pt) | 2017-07-25 |
| KR20160021277A (ko) | 2016-02-24 |
| JP2016523253A (ja) | 2016-08-08 |
| EA201592214A1 (ru) | 2016-06-30 |
| HK1214532A1 (zh) | 2016-07-29 |
| CA2912853A1 (en) | 2014-12-24 |
| CR20150664A (es) | 2016-01-29 |
| US9873684B2 (en) | 2018-01-23 |
| IL242611B (en) | 2018-10-31 |
| CN105324115A (zh) | 2016-02-10 |
| PH12015502621A1 (en) | 2016-03-07 |
| EP3010501B1 (en) | 2021-11-03 |
| PE20160157A1 (es) | 2016-03-18 |
| BR112015031903A8 (pt) | 2019-12-31 |
| EA031077B1 (ru) | 2018-11-30 |
| CL2015003456A1 (es) | 2016-07-29 |
| CN105324115B (zh) | 2019-01-04 |
| JP6576916B2 (ja) | 2019-09-18 |
| EP3010501A1 (en) | 2016-04-27 |
| TW201501710A (zh) | 2015-01-16 |
| JP2019142871A (ja) | 2019-08-29 |
| EP3010501A4 (en) | 2017-02-01 |
| WO2014205138A1 (en) | 2014-12-24 |
| US20160090378A1 (en) | 2016-03-31 |
| SG11201509508YA (en) | 2015-12-30 |
| UA117249C2 (uk) | 2018-07-10 |
| US20170275273A1 (en) | 2017-09-28 |
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