MX2015013939A - Composicion farmaceutica, metodos para tratamiento y sus usos. - Google Patents
Composicion farmaceutica, metodos para tratamiento y sus usos.Info
- Publication number
- MX2015013939A MX2015013939A MX2015013939A MX2015013939A MX2015013939A MX 2015013939 A MX2015013939 A MX 2015013939A MX 2015013939 A MX2015013939 A MX 2015013939A MX 2015013939 A MX2015013939 A MX 2015013939A MX 2015013939 A MX2015013939 A MX 2015013939A
- Authority
- MX
- Mexico
- Prior art keywords
- empagliflozin
- therapeutic uses
- type
- diabetes
- ckd
- Prior art date
Links
- OBWASQILIWPZMG-QZMOQZSNSA-N empagliflozin Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1C1=CC=C(Cl)C(CC=2C=CC(O[C@@H]3COCC3)=CC=2)=C1 OBWASQILIWPZMG-QZMOQZSNSA-N 0.000 title 1
- 229960003345 empagliflozin Drugs 0.000 title 1
- 230000001225 therapeutic effect Effects 0.000 title 1
- 208000020832 chronic kidney disease Diseases 0.000 abstract 2
- 206010018429 Glucose tolerance impaired Diseases 0.000 abstract 1
- 208000001280 Prediabetic State Diseases 0.000 abstract 1
- 206010062237 Renal impairment Diseases 0.000 abstract 1
- 229940123518 Sodium/glucose cotransporter 2 inhibitor Drugs 0.000 abstract 1
- 206010067584 Type 1 diabetes mellitus Diseases 0.000 abstract 1
- 208000030159 metabolic disease Diseases 0.000 abstract 1
- 201000009104 prediabetes syndrome Diseases 0.000 abstract 1
- 208000001072 type 2 diabetes mellitus Diseases 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
- A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
- A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
Abstract
La presente invención se refiere a determinados inhibidores de SGLT-2 para tratar y/o prevenir trastornos metabólicos, tales como diabetes mellitus tipo 2 o tipo 1, o prediabetes, en pacientes con insuficiencia renal o enfermedad renal crónica (CKD).
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201361808804P | 2013-04-05 | 2013-04-05 | |
CA2812519A CA2812519A1 (en) | 2013-04-05 | 2013-04-10 | Pharmaceutical composition, methods for treating and uses thereof |
US201361908991P | 2013-11-26 | 2013-11-26 | |
PCT/EP2014/056657 WO2014161919A1 (en) | 2013-04-05 | 2014-04-03 | Therapeutic uses of empagliflozin |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2015013939A true MX2015013939A (es) | 2016-07-20 |
Family
ID=51787230
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2015013939A MX2015013939A (es) | 2013-04-05 | 2014-04-03 | Composicion farmaceutica, metodos para tratamiento y sus usos. |
MX2020010004A MX2020010004A (es) | 2013-04-05 | 2015-10-01 | Composicion farmaceutica que comprende empagliflozina, metodos para tratamiento y sus usos. |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2020010004A MX2020010004A (es) | 2013-04-05 | 2015-10-01 | Composicion farmaceutica que comprende empagliflozina, metodos para tratamiento y sus usos. |
Country Status (15)
Country | Link |
---|---|
US (1) | US20240066046A1 (es) |
EP (2) | EP3456332A1 (es) |
JP (1) | JP6177992B2 (es) |
KR (3) | KR102318213B1 (es) |
CN (2) | CN109893534A (es) |
AU (1) | AU2014247092B2 (es) |
CA (3) | CA2812519A1 (es) |
DK (1) | DK2981271T3 (es) |
EA (1) | EA033397B1 (es) |
LT (1) | LT2981271T (es) |
MX (2) | MX2015013939A (es) |
PL (1) | PL2981271T3 (es) |
RS (1) | RS58097B1 (es) |
SI (1) | SI2981271T1 (es) |
WO (1) | WO2014161919A1 (es) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20140303097A1 (en) | 2013-04-05 | 2014-10-09 | Boehringer Ingelheim International Gmbh | Pharmaceutical composition, methods for treating and uses thereof |
CA2812519A1 (en) | 2013-04-05 | 2014-10-05 | Boehringer Ingelheim International Gmbh | Pharmaceutical composition, methods for treating and uses thereof |
US11813275B2 (en) | 2013-04-05 | 2023-11-14 | Boehringer Ingelheim International Gmbh | Pharmaceutical composition, methods for treating and uses thereof |
HUE041709T2 (hu) | 2013-04-05 | 2019-05-28 | Boehringer Ingelheim Int | Az empagliflozin terápiás alkalmazásai |
CN113181161A (zh) | 2013-04-18 | 2021-07-30 | 勃林格殷格翰国际有限公司 | 药物组合物、治疗方法及其用途 |
CN105769782A (zh) * | 2014-12-23 | 2016-07-20 | 中美华世通生物医药科技(武汉)有限公司 | 恩格列净片及其制备方法和用途 |
CN106880595A (zh) * | 2015-12-10 | 2017-06-23 | 常州方楠医药技术有限公司 | 一种无定型依帕列净的固体分散体及其制备方法 |
CN109922813A (zh) * | 2016-11-10 | 2019-06-21 | 勃林格殷格翰国际有限公司 | 药物组合物、治疗方法及其用途 |
MX2020003243A (es) | 2017-10-02 | 2020-09-18 | Poxel | Métodos para tratar la insuficiencia cardíaca con fracción de eyección preservada. |
ES2929994T3 (es) | 2018-06-06 | 2022-12-05 | Poxel Sa | Métodos de tratamiento de sujetos que padecen diabetes con enfermedad renal crónica |
MX2020013567A (es) | 2018-06-14 | 2021-05-27 | Poxel | Tableta recubierta con pelicula que comprende un derivado de triazina para su uso en el tratamiento de la diabetes. |
CN110141555A (zh) * | 2019-06-21 | 2019-08-20 | 江苏豪森药业集团有限公司 | 一种恩格列净片及其制备方法 |
CN110721170A (zh) * | 2019-10-24 | 2020-01-24 | 安徽九华华源药业有限公司 | 一种恩格列净片剂及其制备方法 |
WO2022065895A1 (ko) * | 2020-09-24 | 2022-03-31 | 동아에스티 주식회사 | Sglt-2 억제제인 엠파글리플로진 유도체의 신규염 및 염의 수화물 |
Family Cites Families (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2000219632A (ja) * | 1999-01-28 | 2000-08-08 | Toyotama Koryo Kk | カロリー軽減剤 |
DE102004012676A1 (de) * | 2004-03-16 | 2005-10-06 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Glucopyranosyl-substituierte Phenyle, diese Verbindungen enthaltende Arzneimittel, deren Verwendung und Verfahren zu ihrer Herstellung |
JP2006176443A (ja) * | 2004-12-22 | 2006-07-06 | Shionogi & Co Ltd | メラニン凝集ホルモン受容体アンタゴニスト |
UA91546C2 (uk) | 2005-05-03 | 2010-08-10 | Бьорінгер Інгельхайм Інтернаціональ Гмбх | КРИСТАЛІЧНА ФОРМА 1-ХЛОР-4-(β-D-ГЛЮКОПІРАНОЗ-1-ИЛ)-2-[4-((S)-ТЕТРАГІДРОФУРАН-3-ІЛОКСИ)-БЕНЗИЛ]-БЕНЗОЛУ, СПОСІБ ЇЇ ОДЕРЖАННЯ ТА ЇЇ ЗАСТОСУВАННЯ ПРИ ПРИГОТУВАННІ ЛІКАРСЬКИХ ЗАСОБІВ |
EA018495B1 (ru) * | 2006-11-09 | 2013-08-30 | Бёрингер Ингельхайм Интернациональ Гмбх | Комбинированное лечение ингибиторами sglt-2 (натрийзависимый сопереносчик глюкозы 2) и содержащими их фармацевтическими композициями |
MX2009011357A (es) * | 2007-04-20 | 2009-11-05 | Schering Corp | Derivados de tetrahidropirido[4,3-d] pirimidinona y metodos de uso de los mismos. |
CL2008002427A1 (es) | 2007-08-16 | 2009-09-11 | Boehringer Ingelheim Int | Composicion farmaceutica que comprende 1-cloro-4-(b-d-glucopiranos-1-il)-2-[4-((s)-tetrahidrofurano-3-iloxi)bencil]-benceno combinado con 1-[(4-metilquinazolin-2-il)metil]-3-metil-7-(2-butin-1-il)-8-(3-(r)-aminopiperidin-1-il)xantina; y su uso para tratar diabetes mellitus tipo 2. |
EP2261213A1 (en) * | 2008-04-01 | 2010-12-15 | Takeda Pharmaceutical Company Limited | Heterocyclic compound |
BRPI1013640A2 (pt) * | 2009-02-13 | 2019-09-24 | Boehringer Ingelheim Int | composicao farmaceutica, metodos para o tratamento e usos dos mesmos |
PT2395968T (pt) * | 2009-02-13 | 2024-03-05 | Boehringer Ingelheim Int | Composição farmacêutica compreendendo derivados de glucopiranosil difenilmetano, sua forma de dosagem farmacêutica, processo para a sua preparação e suas utilizações para controlo glicémico melhorado num doente |
US10610489B2 (en) * | 2009-10-02 | 2020-04-07 | Boehringer Ingelheim International Gmbh | Pharmaceutical composition, pharmaceutical dosage form, process for their preparation, methods for treating and uses thereof |
US20130035298A1 (en) * | 2011-07-08 | 2013-02-07 | Boehringer Ingelheim International Gmbh | Pharmaceutical composition, methods for treating and uses thereof |
CA2812519A1 (en) | 2013-04-05 | 2014-10-05 | Boehringer Ingelheim International Gmbh | Pharmaceutical composition, methods for treating and uses thereof |
-
2013
- 2013-04-10 CA CA2812519A patent/CA2812519A1/en not_active Abandoned
-
2014
- 2014-04-03 WO PCT/EP2014/056657 patent/WO2014161919A1/en active Application Filing
- 2014-04-03 EP EP18197967.5A patent/EP3456332A1/en active Pending
- 2014-04-03 DK DK14715578.2T patent/DK2981271T3/en active
- 2014-04-03 RS RS20181558A patent/RS58097B1/sr unknown
- 2014-04-03 CN CN201910175299.7A patent/CN109893534A/zh active Pending
- 2014-04-03 LT LTEP14715578.2T patent/LT2981271T/lt unknown
- 2014-04-03 KR KR1020157031845A patent/KR102318213B1/ko active IP Right Review Request
- 2014-04-03 PL PL14715578T patent/PL2981271T3/pl unknown
- 2014-04-03 JP JP2016505816A patent/JP6177992B2/ja active Active
- 2014-04-03 CN CN201480031563.5A patent/CN105377267A/zh active Pending
- 2014-04-03 EP EP14715578.2A patent/EP2981271B1/en active Active
- 2014-04-03 MX MX2015013939A patent/MX2015013939A/es active IP Right Grant
- 2014-04-03 KR KR1020237028350A patent/KR20230125858A/ko not_active Application Discontinuation
- 2014-04-03 KR KR1020217034101A patent/KR20210130844A/ko active Application Filing
- 2014-04-03 CA CA2908635A patent/CA2908635C/en active Active
- 2014-04-03 EA EA201500997A patent/EA033397B1/ru not_active IP Right Cessation
- 2014-04-03 AU AU2014247092A patent/AU2014247092B2/en active Active
- 2014-04-03 SI SI201431030T patent/SI2981271T1/sl unknown
- 2014-04-03 CA CA3121761A patent/CA3121761A1/en active Pending
-
2015
- 2015-10-01 MX MX2020010004A patent/MX2020010004A/es unknown
-
2023
- 2023-10-24 US US18/492,972 patent/US20240066046A1/en active Pending
Also Published As
Publication number | Publication date |
---|---|
CN105377267A (zh) | 2016-03-02 |
EP2981271A1 (en) | 2016-02-10 |
MX2020010004A (es) | 2020-10-14 |
SI2981271T1 (sl) | 2019-02-28 |
JP2016515600A (ja) | 2016-05-30 |
KR102318213B1 (ko) | 2021-10-28 |
CA2908635A1 (en) | 2014-10-09 |
CN109893534A (zh) | 2019-06-18 |
LT2981271T (lt) | 2019-01-10 |
JP6177992B2 (ja) | 2017-08-09 |
DK2981271T3 (en) | 2019-02-04 |
EP3456332A1 (en) | 2019-03-20 |
RS58097B1 (sr) | 2019-02-28 |
CA2812519A1 (en) | 2014-10-05 |
EA201500997A1 (ru) | 2016-04-29 |
EA033397B1 (ru) | 2019-10-31 |
KR20230125858A (ko) | 2023-08-29 |
PL2981271T3 (pl) | 2019-05-31 |
CA3121761A1 (en) | 2014-10-09 |
KR20210130844A (ko) | 2021-11-01 |
EP2981271B1 (en) | 2018-11-14 |
KR20150138860A (ko) | 2015-12-10 |
AU2014247092B2 (en) | 2018-11-01 |
AU2014247092A1 (en) | 2015-09-17 |
US20240066046A1 (en) | 2024-02-29 |
CA2908635C (en) | 2021-07-13 |
WO2014161919A1 (en) | 2014-10-09 |
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Legal Events
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FG | Grant or registration |