MX2015004511A - Tratamiento y/o profilaxis de enfermedades y/o trastornos provocados por tspo. - Google Patents
Tratamiento y/o profilaxis de enfermedades y/o trastornos provocados por tspo.Info
- Publication number
- MX2015004511A MX2015004511A MX2015004511A MX2015004511A MX2015004511A MX 2015004511 A MX2015004511 A MX 2015004511A MX 2015004511 A MX2015004511 A MX 2015004511A MX 2015004511 A MX2015004511 A MX 2015004511A MX 2015004511 A MX2015004511 A MX 2015004511A
- Authority
- MX
- Mexico
- Prior art keywords
- residue
- aliphatic
- unsubstituted
- substituted
- mono
- Prior art date
Links
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Classifications
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- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
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- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
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- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/81—Amides; Imides
- C07D213/82—Amides; Imides in position 3
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
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- Urology & Nephrology (AREA)
- Pain & Pain Management (AREA)
- Hospice & Palliative Care (AREA)
- Immunology (AREA)
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- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP12007118 | 2012-10-11 | ||
| PCT/EP2013/003064 WO2014056620A1 (en) | 2012-10-11 | 2013-10-11 | Treatment and/or prophylaxis of tspo mediated diseases and/or disorders |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2015004511A true MX2015004511A (es) | 2015-07-06 |
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| Application Number | Title | Priority Date | Filing Date |
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| MX2015004511A MX2015004511A (es) | 2012-10-11 | 2013-10-11 | Tratamiento y/o profilaxis de enfermedades y/o trastornos provocados por tspo. |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US9775843B2 (https=) |
| EP (1) | EP2906217A1 (https=) |
| JP (1) | JP2016502503A (https=) |
| CN (1) | CN104994857A (https=) |
| AU (1) | AU2013329832A1 (https=) |
| HK (1) | HK1213175A1 (https=) |
| MX (1) | MX2015004511A (https=) |
| WO (1) | WO2014056620A1 (https=) |
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| EP3319968A1 (en) | 2015-07-06 | 2018-05-16 | Rodin Therapeutics, Inc. | Heterobicyclic n-aminophenyl-amides as inhibitors of histone deacetylase |
| WO2017007756A1 (en) | 2015-07-06 | 2017-01-12 | Rodin Therapeutics, Inc | Hetero-halo inhibitors of histone deacetylase |
| HUE057849T2 (hu) | 2017-01-11 | 2022-06-28 | Alkermes Inc | Hiszton deacetiláz biciklusos gátlói |
| LT3664802T (lt) | 2017-08-07 | 2022-06-27 | Alkermes, Inc. | Bicikliniai histonų deacetilazės inhibitoriai |
| CN111840267A (zh) * | 2020-08-05 | 2020-10-30 | 牡丹江医学院 | 一种治疗小儿口腔黏膜疾病的药物及其制备方法 |
| AU2024282841A1 (en) * | 2023-06-02 | 2025-12-11 | The Johns Hopkins University | Uses of psma-targeting and tspo-targeting compounds for evaluation of injuries in the peripheral nervous system |
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| US6756382B2 (en) * | 1999-06-10 | 2004-06-29 | 3M Innovative Properties Company | Amide substituted imidazoquinolines |
| DE10239303B4 (de) | 2002-08-27 | 2006-08-03 | Siemens Ag | Energieautark modulierter Backscatter-Transponder |
| US20050197350A1 (en) * | 2003-03-31 | 2005-09-08 | Taisho Pharmaceutical Co., Ltd. | Novel quinoline, tetrahydroquinazoline, and pyrimidine derivatives and methods of treatment related to the use thereof |
| SE0302323D0 (sv) * | 2003-08-28 | 2003-08-28 | Astrazeneca Ab | Novel compounds |
| DE602004026095D1 (de) | 2003-11-24 | 2010-04-29 | Pfizer | Chinoloncarbonsäureverbindungen mit 5-ht4-rezeptoragonistischer wirkung |
| EP1912946B1 (en) * | 2005-07-20 | 2009-05-27 | Eli Lilly And Company | Pyridine derivatives as dipeptedyl peptidase inhibitors |
| DE102007044277A1 (de) * | 2007-09-17 | 2009-03-19 | Grünenthal GmbH | Substituierte Nicotinamid-Verbindungen und deren Verwendung in Arzneimitteln |
| CN101392001A (zh) * | 2007-09-21 | 2009-03-25 | 上海恒瑞医药有限公司 | 氨甲酰类衍生物、其制备方法及其在医药上的用途 |
| TWI461197B (zh) | 2009-03-12 | 2014-11-21 | 2-mercaptoquinoline-3-carboxamide as a KCNQ2 / 3 modifier | |
| TWI475020B (zh) | 2009-03-12 | 2015-03-01 | The substituted nicotine amide as a KCNQ2 / 3 modifier | |
| JP6023926B2 (ja) * | 2010-02-12 | 2016-11-09 | 株式会社ＡｓｋＡｔ | 認知症治療のための５−ｈｔ４受容体アゴニスト |
| CA2805932A1 (en) | 2010-08-27 | 2012-03-01 | Gruenenthal Gmbh | Substituted 2-amino-quinoline-3-carboxamides as kcnq2/3 modulators |
| CA2804824A1 (en) * | 2010-08-27 | 2012-03-01 | Gruenenthal Gmbh | Substituted quinoline-3-carboxamides as kcnq2/3 modulators |
| RU2595894C2 (ru) * | 2010-08-27 | 2016-08-27 | Грюненталь Гмбх | Замещенные 2-окси-хинолин-3-карбоксамиды в качестве модуляторов kcnq2/3 |
| MX342459B (es) * | 2010-08-27 | 2016-09-29 | Grünenthal Gmbh * | 2-oxo- y 2-tioxo-dihidroquinolin-3-carboxamidas sustituidas, como moduladores de kcnq2/3. |
| US9168259B2 (en) * | 2010-10-20 | 2015-10-27 | Grünenthal GmbH | Substituted 6-amino-nicotinamides as KCNQ2/3 modulators |
| JP5947307B2 (ja) * | 2010-10-20 | 2016-07-06 | グリュネンタール・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング | Ｋｃｎｑ２／３調節因子としての置換６−アミノ−ニコチンアミド |
-
2013
- 2013-10-11 CN CN201380064616.9A patent/CN104994857A/zh active Pending
- 2013-10-11 AU AU2013329832A patent/AU2013329832A1/en not_active Abandoned
- 2013-10-11 HK HK16101006.2A patent/HK1213175A1/zh unknown
- 2013-10-11 JP JP2015536018A patent/JP2016502503A/ja active Pending
- 2013-10-11 WO PCT/EP2013/003064 patent/WO2014056620A1/en not_active Ceased
- 2013-10-11 EP EP13776727.3A patent/EP2906217A1/en not_active Ceased
- 2013-10-11 US US14/434,943 patent/US9775843B2/en not_active Expired - Fee Related
- 2013-10-11 MX MX2015004511A patent/MX2015004511A/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| US20150290203A1 (en) | 2015-10-15 |
| CN104994857A (zh) | 2015-10-21 |
| JP2016502503A (ja) | 2016-01-28 |
| AU2013329832A1 (en) | 2015-05-28 |
| US9775843B2 (en) | 2017-10-03 |
| HK1213175A1 (zh) | 2016-06-30 |
| WO2014056620A1 (en) | 2014-04-17 |
| EP2906217A1 (en) | 2015-08-19 |
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