MX2014011165A - Cabazal integrado de lectura optoelectrónica y cartucho fluído útil para secuenciación de ácidos nucleicos. - Google Patents

Cabazal integrado de lectura optoelectrónica y cartucho fluído útil para secuenciación de ácidos nucleicos.

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Publication number
MX2014011165A
MX2014011165A MX2014011165A MX2014011165A MX2014011165A MX 2014011165 A MX2014011165 A MX 2014011165A MX 2014011165 A MX2014011165 A MX 2014011165A MX 2014011165 A MX2014011165 A MX 2014011165A MX 2014011165 A MX2014011165 A MX 2014011165A
Authority
MX
Mexico
Prior art keywords
flow cell
read head
nucleic acid
cartridge
acid sequencing
Prior art date
Application number
MX2014011165A
Other languages
English (en)
Other versions
MX337140B (es
Inventor
Dale Buermann
John A Moon
Bryan Crane
Mark Wang
Stanley S Hong
Jason Harris
Matthew Hage
Mark J Nibbe
Original Assignee
Illumina Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Illumina Inc filed Critical Illumina Inc
Publication of MX2014011165A publication Critical patent/MX2014011165A/es
Publication of MX337140B publication Critical patent/MX337140B/es

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    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/52—Containers specially adapted for storing or dispensing a reagent
    • B01L3/527—Containers specially adapted for storing or dispensing a reagent for a plurality of reagents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869—Methods for sequencing
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869—Methods for sequencing
    • C12Q1/6874—Methods for sequencing involving nucleic acid arrays, e.g. sequencing by hybridisation
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    • G01N21/64—Fluorescence; Phosphorescence
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    • G01—MEASURING; TESTING
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    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
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    • B01L2400/0475—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
    • B01L2400/0487—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure fluid pressure, pneumatics
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    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
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    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502715—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by interfacing components, e.g. fluidic, electrical, optical or mechanical interfaces
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/01—Arrangements or apparatus for facilitating the optical investigation
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    • G01N2021/0307—Insert part in cell
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    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
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    • G—PHYSICS
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    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
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    • G01N21/01—Arrangements or apparatus for facilitating the optical investigation
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    • G—PHYSICS
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    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N2021/6417—Spectrofluorimetric devices
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    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • G01N2021/6439—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes" with indicators, stains, dyes, tags, labels, marks
    • G01N2021/6441—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes" with indicators, stains, dyes, tags, labels, marks with two or more labels
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    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
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    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
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    • G01N21/645—Specially adapted constructive features of fluorimeters
    • G01N2021/6482—Sample cells, cuvettes
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    • G01N2201/00—Features of devices classified in G01N21/00
    • G01N2201/06—Illumination; Optics
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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
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  • Engineering & Computer Science (AREA)
  • General Physics & Mathematics (AREA)
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  • Wood Science & Technology (AREA)
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  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Clinical Laboratory Science (AREA)
  • Biomedical Technology (AREA)
  • Optics & Photonics (AREA)
  • Medicinal Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Hematology (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Optical Measuring Cells (AREA)
  • Saccharide Compounds (AREA)
  • Catalysts (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)

Abstract

Un aparato de detección que comprende un cabezal de lectura que incluye una pluralidad de microfluorómetros colocados para adquirir de manera simultánea una pluralidad de imágenes de campo amplio en un plano común; y (b) una plataforma de traslado configurada para mover el cabezal de lectura a lo largo de un sustrato que está en el plano común. El sustrato puede ser una celda de flujo que está incluida en un cartucho, el cartucho también puede incluir un alojamiento para (i) un depósito de muestras; (ii) una línea fluídica entre el depósito de muestras y la celda de flujo; (iii) varios depósitos de reactivos en comunicación de fluidos con la celda de flujo, (iv) al menos una válvula configurada para mediar la comunicación de fluidos entre los depósitos y la celda de flujo; (v) al menos una fuente de presión configurada para mover los líquidos de los depósitos a la celda de flujo. El aparato de detección y el cartucho se pueden utilizar juntos o independientes uno del otro.
MX2014011165A 2012-04-03 2013-02-13 Cabazal integrado de lectura optoelectrónica y cartucho fluído útil para secuenciación de ácidos nucleicos. MX337140B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261619784P 2012-04-03 2012-04-03
PCT/US2013/025963 WO2013151622A1 (en) 2012-04-03 2013-02-13 Integrated optoelectronic read head and fluidic cartridge useful for nucleic acid sequencing

Publications (2)

Publication Number Publication Date
MX2014011165A true MX2014011165A (es) 2015-03-19
MX337140B MX337140B (es) 2016-02-12

Family

ID=47891920

Family Applications (1)

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MX2014011165A MX337140B (es) 2012-04-03 2013-02-13 Cabazal integrado de lectura optoelectrónica y cartucho fluído útil para secuenciación de ácidos nucleicos.

Country Status (14)

Country Link
US (5) US9193996B2 (es)
EP (2) EP2834622B1 (es)
JP (1) JP6159391B2 (es)
KR (3) KR102118211B1 (es)
CN (1) CN204832037U (es)
AU (4) AU2013243998B2 (es)
BR (2) BR122021002358B8 (es)
CA (2) CA3138752C (es)
ES (1) ES2949570T3 (es)
HK (1) HK1201582A1 (es)
IL (3) IL234864B (es)
IN (1) IN2014DN07992A (es)
MX (1) MX337140B (es)
WO (1) WO2013151622A1 (es)

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