MX2014004658A - Ácidos nucleícos que unen glucagón. - Google Patents
Ácidos nucleícos que unen glucagón.Info
- Publication number
- MX2014004658A MX2014004658A MX2014004658A MX2014004658A MX2014004658A MX 2014004658 A MX2014004658 A MX 2014004658A MX 2014004658 A MX2014004658 A MX 2014004658A MX 2014004658 A MX2014004658 A MX 2014004658A MX 2014004658 A MX2014004658 A MX 2014004658A
- Authority
- MX
- Mexico
- Prior art keywords
- nucleic acid
- seq
- absent
- acid molecule
- nucleotides
- Prior art date
Links
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Classifications
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/115—Aptamers, i.e. nucleic acids binding a target molecule specifically and with high affinity without hybridising therewith ; Nucleic acids binding to non-nucleic acids, e.g. aptamers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7088—Compounds having three or more nucleosides or nucleotides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/16—Aptamers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/30—Chemical structure
- C12N2310/35—Nature of the modification
- C12N2310/351—Conjugate
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2320/00—Applications; Uses
- C12N2320/30—Special therapeutic applications
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
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- Molecular Biology (AREA)
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- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
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- Biotechnology (AREA)
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- Pharmacology & Pharmacy (AREA)
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- Public Health (AREA)
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- Diabetes (AREA)
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- Chemical Kinetics & Catalysis (AREA)
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- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Endocrinology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Peptides Or Proteins (AREA)
- Medicinal Preparation (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP11008467 | 2011-10-21 | ||
| EP11008473 | 2011-10-21 | ||
| EP12000107 | 2012-01-10 | ||
| PCT/EP2012/000089 WO2012095303A1 (en) | 2011-01-10 | 2012-01-10 | Nucleic acid molecule having binding affinity to a target molecule and a method for generating the same |
| PCT/EP2012/004421 WO2013056852A1 (en) | 2011-10-21 | 2012-10-22 | Glucagon binding nucleic acids |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2014004658A true MX2014004658A (es) | 2015-08-13 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2014004658A MX2014004658A (es) | 2011-10-21 | 2012-10-22 | Ácidos nucleícos que unen glucagón. |
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| Country | Link |
|---|---|
| US (1) | US20150232852A1 (enExample) |
| EP (1) | EP2768960A1 (enExample) |
| JP (1) | JP2014533098A (enExample) |
| KR (1) | KR20140083039A (enExample) |
| CN (1) | CN103958682A (enExample) |
| AU (1) | AU2012325233A1 (enExample) |
| BR (1) | BR112014009104A2 (enExample) |
| CA (1) | CA2852802A1 (enExample) |
| IL (1) | IL231980A0 (enExample) |
| MX (1) | MX2014004658A (enExample) |
| SG (1) | SG11201401362TA (enExample) |
| WO (1) | WO2013056852A1 (enExample) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR112014016877B1 (pt) | 2012-01-10 | 2022-03-15 | Aptarion Biotech Ag | Molécula de l-ácido nucleico capaz de se ligar a c5a humana, seus usos, bem como composição farmacêutica, complexo, método para a seleção de um antagonista de uma atividade mediada por c5a e kit para a detecção de c5a |
| CN103343126B (zh) * | 2013-07-19 | 2015-12-02 | 暨南大学 | 莱克多巴胺适配体与检测莱克多巴胺的适配体电化学生物传感器 |
| US10513536B2 (en) | 2014-02-03 | 2019-12-24 | Noxxon Pharma Ag | Methods for the preparation of a polyalkoxylated nucleic acid molecule |
| ES2607639B1 (es) * | 2015-09-30 | 2018-02-28 | Urquima, S.A | Sal de ácido maleico de un intermedio de silodosina |
| US20190062441A1 (en) * | 2015-10-07 | 2019-02-28 | Remd Biotherapeutics, Inc. | Methods For Treating Rare Genetic Disorders Using Glucagon Receptor Antagonistic Antibodies |
| DE17829597T1 (de) | 2016-11-30 | 2019-12-05 | Noxxon Pharma Ag | Verfahren zur polyalkoxylierung von nukleinsäuren zur rückgewinnung und wiederverwendung einer überschüssigen polyalkoxylierungsreagenz |
| JP7418788B2 (ja) * | 2019-10-16 | 2024-01-22 | 国立研究開発法人産業技術総合研究所 | グルカゴン認識ペプチド並びにグルカゴン検出法 |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| US6011020A (en) | 1990-06-11 | 2000-01-04 | Nexstar Pharmaceuticals, Inc. | Nucleic acid ligand complexes |
| US6395029B1 (en) | 1999-01-19 | 2002-05-28 | The Children's Hospital Of Philadelphia | Sustained delivery of polyionic bioactive agents |
| US6677136B2 (en) * | 2000-05-03 | 2004-01-13 | Amgen Inc. | Glucagon antagonists |
| US6652886B2 (en) | 2001-02-16 | 2003-11-25 | Expression Genetics | Biodegradable cationic copolymers of poly (alkylenimine) and poly (ethylene glycol) for the delivery of bioactive agents |
| ES2346640T4 (es) | 2001-10-26 | 2011-04-26 | Noxxon Pharma Ag | Ácido l-nucleico modificado. |
| EP1306382A1 (de) | 2001-10-26 | 2003-05-02 | Noxxon Pharma AG | Modifizierte L-Nukleinsäure |
| EP2138575B8 (en) | 2002-02-20 | 2013-07-24 | Mersana Therapeutics, Inc. | Conjugates comprising a biodegradable polymer and uses therefor |
| KR20060015505A (ko) | 2003-04-13 | 2006-02-17 | 엔존 파마슈티컬즈, 인코포레이티드 | 올리고뉴클레오타이드 전구약물 |
| GB0314472D0 (en) | 2003-06-20 | 2003-07-23 | Warwick Effect Polymers Ltd | Polymer |
| US20090281296A1 (en) | 2004-02-09 | 2009-11-12 | Supramol Parenteral Colloid Gmbh | Process for the production of conjugates from polysaccharides and polynucelotides |
| ES2741524T3 (es) | 2004-03-23 | 2020-02-11 | Ascendis Pharma Gmbh | Profármaco polimérico con un enlazador autoinmolador |
| WO2006052790A2 (en) | 2004-11-05 | 2006-05-18 | The Children's Hospital Of Philadelphia | Biodegradable linkers for molecular therapies |
| CA2607185A1 (en) * | 2005-05-04 | 2006-11-09 | Noxxon Pharma Ag | Intracellular active agents |
| JP4706019B2 (ja) * | 2005-07-08 | 2011-06-22 | 国立大学法人東京農工大学 | アプタマーの同定方法 |
| CN101534643A (zh) | 2006-09-15 | 2009-09-16 | 安佐制药股份有限公司 | 用于递送寡核苷酸的基于位阻酯的生物可降解连接体 |
| EP2407558A1 (en) | 2006-10-31 | 2012-01-18 | Noxxon Pharma AG | Methods for the detection of a single- or double-stranded nucleic acid molecule |
| KR20140026357A (ko) * | 2011-01-10 | 2014-03-05 | 녹손 파르마 아게 | 목표 분자에 결합력을 갖는 핵산 및 이를 제조하는 방법 |
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2012
- 2012-10-22 JP JP2014536148A patent/JP2014533098A/ja active Pending
- 2012-10-22 EP EP12775626.0A patent/EP2768960A1/en not_active Withdrawn
- 2012-10-22 SG SG11201401362TA patent/SG11201401362TA/en unknown
- 2012-10-22 BR BR112014009104A patent/BR112014009104A2/pt not_active IP Right Cessation
- 2012-10-22 US US14/351,574 patent/US20150232852A1/en not_active Abandoned
- 2012-10-22 KR KR1020147013385A patent/KR20140083039A/ko not_active Withdrawn
- 2012-10-22 AU AU2012325233A patent/AU2012325233A1/en not_active Abandoned
- 2012-10-22 CN CN201280058153.0A patent/CN103958682A/zh active Pending
- 2012-10-22 WO PCT/EP2012/004421 patent/WO2013056852A1/en not_active Ceased
- 2012-10-22 MX MX2014004658A patent/MX2014004658A/es unknown
- 2012-10-22 CA CA2852802A patent/CA2852802A1/en not_active Abandoned
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2014
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Also Published As
| Publication number | Publication date |
|---|---|
| CN103958682A (zh) | 2014-07-30 |
| IL231980A0 (en) | 2014-05-28 |
| AU2012325233A1 (en) | 2014-04-24 |
| SG11201401362TA (en) | 2014-05-29 |
| JP2014533098A (ja) | 2014-12-11 |
| US20150232852A1 (en) | 2015-08-20 |
| KR20140083039A (ko) | 2014-07-03 |
| BR112014009104A2 (pt) | 2017-04-18 |
| WO2013056852A1 (en) | 2013-04-25 |
| EP2768960A1 (en) | 2014-08-27 |
| CA2852802A1 (en) | 2013-04-25 |
| AU2012325233A2 (en) | 2014-04-24 |
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