KR20140083039A - 글루카곤 결합형 핵산 - Google Patents
글루카곤 결합형 핵산 Download PDFInfo
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- KR20140083039A KR20140083039A KR1020147013385A KR20147013385A KR20140083039A KR 20140083039 A KR20140083039 A KR 20140083039A KR 1020147013385 A KR1020147013385 A KR 1020147013385A KR 20147013385 A KR20147013385 A KR 20147013385A KR 20140083039 A KR20140083039 A KR 20140083039A
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- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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- C12N2310/00—Structure or type of the nucleic acid
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| BR112014016877B1 (pt) | 2012-01-10 | 2022-03-15 | Aptarion Biotech Ag | Molécula de l-ácido nucleico capaz de se ligar a c5a humana, seus usos, bem como composição farmacêutica, complexo, método para a seleção de um antagonista de uma atividade mediada por c5a e kit para a detecção de c5a |
| CN103343126B (zh) * | 2013-07-19 | 2015-12-02 | 暨南大学 | 莱克多巴胺适配体与检测莱克多巴胺的适配体电化学生物传感器 |
| US10513536B2 (en) | 2014-02-03 | 2019-12-24 | Noxxon Pharma Ag | Methods for the preparation of a polyalkoxylated nucleic acid molecule |
| ES2607639B1 (es) * | 2015-09-30 | 2018-02-28 | Urquima, S.A | Sal de ácido maleico de un intermedio de silodosina |
| US20190062441A1 (en) * | 2015-10-07 | 2019-02-28 | Remd Biotherapeutics, Inc. | Methods For Treating Rare Genetic Disorders Using Glucagon Receptor Antagonistic Antibodies |
| DE17829597T1 (de) | 2016-11-30 | 2019-12-05 | Noxxon Pharma Ag | Verfahren zur polyalkoxylierung von nukleinsäuren zur rückgewinnung und wiederverwendung einer überschüssigen polyalkoxylierungsreagenz |
| JP7418788B2 (ja) * | 2019-10-16 | 2024-01-22 | 国立研究開発法人産業技術総合研究所 | グルカゴン認識ペプチド並びにグルカゴン検出法 |
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| US6395029B1 (en) | 1999-01-19 | 2002-05-28 | The Children's Hospital Of Philadelphia | Sustained delivery of polyionic bioactive agents |
| US6677136B2 (en) * | 2000-05-03 | 2004-01-13 | Amgen Inc. | Glucagon antagonists |
| US6652886B2 (en) | 2001-02-16 | 2003-11-25 | Expression Genetics | Biodegradable cationic copolymers of poly (alkylenimine) and poly (ethylene glycol) for the delivery of bioactive agents |
| ES2346640T4 (es) | 2001-10-26 | 2011-04-26 | Noxxon Pharma Ag | Ácido l-nucleico modificado. |
| EP1306382A1 (de) | 2001-10-26 | 2003-05-02 | Noxxon Pharma AG | Modifizierte L-Nukleinsäure |
| EP2138575B8 (en) | 2002-02-20 | 2013-07-24 | Mersana Therapeutics, Inc. | Conjugates comprising a biodegradable polymer and uses therefor |
| KR20060015505A (ko) | 2003-04-13 | 2006-02-17 | 엔존 파마슈티컬즈, 인코포레이티드 | 올리고뉴클레오타이드 전구약물 |
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| ES2741524T3 (es) | 2004-03-23 | 2020-02-11 | Ascendis Pharma Gmbh | Profármaco polimérico con un enlazador autoinmolador |
| WO2006052790A2 (en) | 2004-11-05 | 2006-05-18 | The Children's Hospital Of Philadelphia | Biodegradable linkers for molecular therapies |
| CA2607185A1 (en) * | 2005-05-04 | 2006-11-09 | Noxxon Pharma Ag | Intracellular active agents |
| JP4706019B2 (ja) * | 2005-07-08 | 2011-06-22 | 国立大学法人東京農工大学 | アプタマーの同定方法 |
| CN101534643A (zh) | 2006-09-15 | 2009-09-16 | 安佐制药股份有限公司 | 用于递送寡核苷酸的基于位阻酯的生物可降解连接体 |
| EP2407558A1 (en) | 2006-10-31 | 2012-01-18 | Noxxon Pharma AG | Methods for the detection of a single- or double-stranded nucleic acid molecule |
| KR20140026357A (ko) * | 2011-01-10 | 2014-03-05 | 녹손 파르마 아게 | 목표 분자에 결합력을 갖는 핵산 및 이를 제조하는 방법 |
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| MX2014004658A (es) | 2015-08-13 |
| CN103958682A (zh) | 2014-07-30 |
| IL231980A0 (en) | 2014-05-28 |
| AU2012325233A1 (en) | 2014-04-24 |
| SG11201401362TA (en) | 2014-05-29 |
| JP2014533098A (ja) | 2014-12-11 |
| US20150232852A1 (en) | 2015-08-20 |
| BR112014009104A2 (pt) | 2017-04-18 |
| WO2013056852A1 (en) | 2013-04-25 |
| EP2768960A1 (en) | 2014-08-27 |
| CA2852802A1 (en) | 2013-04-25 |
| AU2012325233A2 (en) | 2014-04-24 |
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