KR20140083039A - 글루카곤 결합형 핵산 - Google Patents
글루카곤 결합형 핵산 Download PDFInfo
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- KR20140083039A KR20140083039A KR1020147013385A KR20147013385A KR20140083039A KR 20140083039 A KR20140083039 A KR 20140083039A KR 1020147013385 A KR1020147013385 A KR 1020147013385A KR 20147013385 A KR20147013385 A KR 20147013385A KR 20140083039 A KR20140083039 A KR 20140083039A
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| PCT/EP2012/000089 WO2012095303A1 (en) | 2011-01-10 | 2012-01-10 | Nucleic acid molecule having binding affinity to a target molecule and a method for generating the same |
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| PT2802660T (pt) | 2012-01-10 | 2020-04-21 | Aptarion Biotech Ag | Novos ácidos nucleicos que se ligam a c5a |
| CN103343126B (zh) * | 2013-07-19 | 2015-12-02 | 暨南大学 | 莱克多巴胺适配体与检测莱克多巴胺的适配体电化学生物传感器 |
| WO2015113776A1 (en) * | 2014-02-03 | 2015-08-06 | Noxxon Pharma Ag | Methods for the preparation of a polyalkoxylated nucleic acid molecule |
| ES2607639B1 (es) * | 2015-09-30 | 2018-02-28 | Urquima, S.A | Sal de ácido maleico de un intermedio de silodosina |
| WO2017062693A1 (en) * | 2015-10-07 | 2017-04-13 | Remd Biotherapeutics, Inc. | Methods for treating rare genetic disorders using glucagon receptor antagonistic antibodies |
| BR112019009373A8 (pt) | 2016-11-30 | 2023-04-11 | Noxxon Pharma Ag | Método para polialcoxilação de ácidos nucleicos que permite recuperação e reutilização do excesso de reagente de polialcoxilação |
| JP7418788B2 (ja) * | 2019-10-16 | 2024-01-22 | 国立研究開発法人産業技術総合研究所 | グルカゴン認識ペプチド並びにグルカゴン検出法 |
| WO2025205956A1 (ja) * | 2024-03-26 | 2025-10-02 | 国立研究開発法人産業技術総合研究所 | グルカゴン認識ペプチド並びにグルカゴン検出法 |
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| US6395029B1 (en) | 1999-01-19 | 2002-05-28 | The Children's Hospital Of Philadelphia | Sustained delivery of polyionic bioactive agents |
| US6677136B2 (en) * | 2000-05-03 | 2004-01-13 | Amgen Inc. | Glucagon antagonists |
| US6652886B2 (en) | 2001-02-16 | 2003-11-25 | Expression Genetics | Biodegradable cationic copolymers of poly (alkylenimine) and poly (ethylene glycol) for the delivery of bioactive agents |
| EP1306382A1 (de) | 2001-10-26 | 2003-05-02 | Noxxon Pharma AG | Modifizierte L-Nukleinsäure |
| EP1438321B1 (de) | 2001-10-26 | 2010-05-26 | Noxxon Pharma AG | Modifizierte l-nukleinsäure |
| WO2003070823A2 (en) | 2002-02-20 | 2003-08-28 | The General Hospital Corporation | Conjugates comprising a biodegradable polymer and uses therefor |
| AU2004230927B9 (en) | 2003-04-13 | 2011-12-01 | Enzon Pharmaceuticals, Inc. | Polymeric oligonucleotide prodrugs |
| GB0314472D0 (en) | 2003-06-20 | 2003-07-23 | Warwick Effect Polymers Ltd | Polymer |
| KR101189555B1 (ko) | 2004-02-09 | 2012-10-16 | 주프라몰 파렌테랄 콜로이츠 게엠베하 | 폴리사카라이드 및 폴리뉴클레오티드로부터 접합체를제조하는 방법 |
| CA2786794C (en) | 2004-03-23 | 2017-09-12 | Complex Biosystems Gmbh | Aromatic polymeric cascade prodrug linker reagent |
| EP1807092B1 (en) | 2004-11-05 | 2016-09-07 | The Children's Hospital of Philadelphia | Biodegradable linkers for molecular therapies |
| MX2007013760A (es) * | 2005-05-04 | 2008-01-28 | Noxxon Pharma Ag | Uso novedoso de spiegelmers. |
| JP4706019B2 (ja) * | 2005-07-08 | 2011-06-22 | 国立大学法人東京農工大学 | アプタマーの同定方法 |
| WO2008034122A2 (en) | 2006-09-15 | 2008-03-20 | Enzon Pharmaceuticals, Inc. | Hindered ester-based biodegradable linkers for oligonucleotide delivery |
| WO2008052774A2 (en) | 2006-10-31 | 2008-05-08 | Noxxon Pharma Ag | Methods for detection of a single- or double-stranded nucleic acid molecule |
| WO2012095303A1 (en) * | 2011-01-10 | 2012-07-19 | Noxxon Pharma Ag | Nucleic acid molecule having binding affinity to a target molecule and a method for generating the same |
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| EP2768960A1 (en) | 2014-08-27 |
| MX2014004658A (es) | 2015-08-13 |
| US20150232852A1 (en) | 2015-08-20 |
| SG11201401362TA (en) | 2014-05-29 |
| BR112014009104A2 (pt) | 2017-04-18 |
| IL231980A0 (en) | 2014-05-28 |
| AU2012325233A2 (en) | 2014-04-24 |
| JP2014533098A (ja) | 2014-12-11 |
| CN103958682A (zh) | 2014-07-30 |
| CA2852802A1 (en) | 2013-04-25 |
| WO2013056852A1 (en) | 2013-04-25 |
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