MX2013003892A - Composicion farmaceutica liquida para el suministro de ingredientes activos. - Google Patents
Composicion farmaceutica liquida para el suministro de ingredientes activos.Info
- Publication number
- MX2013003892A MX2013003892A MX2013003892A MX2013003892A MX2013003892A MX 2013003892 A MX2013003892 A MX 2013003892A MX 2013003892 A MX2013003892 A MX 2013003892A MX 2013003892 A MX2013003892 A MX 2013003892A MX 2013003892 A MX2013003892 A MX 2013003892A
- Authority
- MX
- Mexico
- Prior art keywords
- active ingredients
- compositions
- delivery
- pharmaceutical composition
- liquid pharmaceutical
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/24—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0043—Nose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0046—Ear
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Ophthalmology & Optometry (AREA)
- Otolaryngology (AREA)
- Dermatology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dispersion Chemistry (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
La invención proporciona composiciones farmacéuticas novedosas basadas en alcanos semifluorados que son útiles como portadores para un intervalo amplio de ingredientes activos. Los ingredientes activos preferidos incluyen sustancias de fármaco pobremente solubles en agua y/o hidrolíticamente sensibles. Las composiciones se asignan como suspensiones y tienen propiedades físicas superiores que las hacen altamente útiles como sistemas de suministro farmacéutico. Las composiciones pueden administrarse tópicamente en el ojo, o inyectarse por medio de vía subcutánea o intramuscular. La invención además proporciona kits que comprenden tales composiciones.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP10188242A EP2444063A1 (en) | 2010-10-20 | 2010-10-20 | Liquid pharmaceutical compositions for the delivery of active ingredients |
PCT/EP2011/068141 WO2012052418A1 (en) | 2010-10-20 | 2011-10-18 | Liquid pharmaceutical composition for the delivery of active ingredients |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2013003892A true MX2013003892A (es) | 2013-07-05 |
Family
ID=43608363
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2013003892A MX2013003892A (es) | 2010-10-20 | 2011-10-18 | Composicion farmaceutica liquida para el suministro de ingredientes activos. |
Country Status (16)
Country | Link |
---|---|
US (3) | US9757459B2 (es) |
EP (2) | EP2444063A1 (es) |
JP (1) | JP5770297B2 (es) |
KR (1) | KR101773225B1 (es) |
CN (1) | CN103153281B (es) |
AU (1) | AU2011317673B2 (es) |
BR (1) | BR112013007473B1 (es) |
CA (1) | CA2813016C (es) |
DK (1) | DK2629754T3 (es) |
ES (1) | ES2528105T3 (es) |
HK (1) | HK1182010A1 (es) |
IN (1) | IN2013DN02524A (es) |
MX (1) | MX2013003892A (es) |
PL (1) | PL2629754T3 (es) |
PT (1) | PT2629754E (es) |
WO (1) | WO2012052418A1 (es) |
Families Citing this family (31)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2547323B1 (en) | 2010-03-17 | 2016-01-27 | Novaliq GmbH | Pharmaceutical composition for treatment of increased intraocular pressure |
EP2444063A1 (en) | 2010-10-20 | 2012-04-25 | Novaliq GmbH | Liquid pharmaceutical compositions for the delivery of active ingredients |
EP2462921A1 (en) | 2010-11-11 | 2012-06-13 | Novaliq GmbH | Liquid pharmaceutical compositions for the treatment of a posterior eye disease |
CA2834855C (en) | 2011-05-25 | 2020-12-29 | Novaliq Gmbh | Topical pharmaceutical composition based on semifluorinated alkanes |
EP2714008B1 (en) | 2011-05-25 | 2016-12-14 | Novaliq GmbH | Pharmaceutical composition for administration to nails |
DK2806886T3 (en) | 2012-01-23 | 2017-06-06 | Novaliq Gmbh | STABILIZED PROTEIN COMPOSITIONS BASED ON SEMIFLUORED ALKANES |
MX363182B (es) | 2012-09-12 | 2019-03-13 | Novaliq Gmbh | Composiciones que comprenden mezclas de alcanos semifluorados. |
AU2013314303B2 (en) | 2012-09-12 | 2018-01-18 | Novaliq Gmbh | Semifluorinated alkane compositions |
EP2948134B1 (en) | 2013-01-24 | 2020-03-04 | Palvella Therapeutics, Inc. | Compositions for transdermal delivery of mtor inhibitors |
JP6503349B2 (ja) | 2013-07-23 | 2019-04-17 | ノバリック ゲーエムベーハー | 安定化された抗体組成物 |
JP6657193B2 (ja) * | 2014-09-17 | 2020-03-04 | パンオプティカ,インコーポレイテッド | 薬物送達および前眼部保護のための眼用製剤 |
EP3495023B1 (en) | 2015-09-30 | 2020-04-22 | Novaliq GmbH | Semifluorinated compounds and their compositions |
US11154513B2 (en) * | 2015-09-30 | 2021-10-26 | Novaliq Gmbh | Semifluorinated compounds |
WO2017220625A1 (en) | 2016-06-23 | 2017-12-28 | Novaliq Gmbh | Topical administration method |
EP3515420B1 (en) | 2016-09-22 | 2023-11-08 | Novaliq GmbH | Pharmaceutical compositions for use in the therapy of blepharitis |
KR20190057338A (ko) | 2016-09-23 | 2019-05-28 | 노바리크 게엠베하 | 시클로스포린을 포함하는 안과 조성물 |
AU2017333420A1 (en) * | 2016-09-28 | 2019-04-04 | Novaliq Gmbh | Compositions comprising a cannabinoid receptor binding ligand |
US10751295B2 (en) * | 2016-11-09 | 2020-08-25 | Specialty Drug and Device, LLC | Compositions and methods for the removal of ear wax |
AU2017380769B2 (en) * | 2016-12-22 | 2023-12-21 | Novaliq Gmbh | Compositions comprising tacrolimus for the treatment of intraocular inflammatory eye diseases |
IL267869B2 (en) | 2017-01-06 | 2023-10-01 | Palvella Therapeutics Inc | Non-aqueous preparations of mTOR inhibitors and methods of use |
AU2018253944B2 (en) * | 2017-04-21 | 2022-09-15 | Dermaliq Therapeutics, Inc. | Iodine compositions |
EP3619186B1 (en) | 2017-05-05 | 2021-02-17 | Novaliq GmbH | Process for the production of semifluorinated alkanes |
EP3621601A1 (en) | 2017-05-12 | 2020-03-18 | Novaliq GmbH | Pharmaceutical compositions comprosing semifluorinated alkanes for the treatment of contact lense-related conditions |
US11723861B2 (en) | 2017-09-27 | 2023-08-15 | Novaliq Gmbh | Ophthalmic compositions comprising latanoprost for use in the treatment of ocular diseases |
US11896559B2 (en) | 2017-10-04 | 2024-02-13 | Novaliq Gmbh | Opthalmic compositions comprising F6H8 |
WO2019166631A1 (en) | 2018-03-02 | 2019-09-06 | Novaliq Gmbh | Pharmaceutical compositions comprising nebivolol |
SG11202007860XA (en) * | 2018-03-28 | 2020-09-29 | Novaliq Gmbh | Pharmaceutical composition comprising timolol |
WO2020010073A1 (en) | 2018-07-02 | 2020-01-09 | Palvella Therapeutics, Inc. | ANHYDROUS COMPOSITIONS OF mTOR INHIBITORS AND METHODS OF USE |
CA3111870C (en) | 2018-09-27 | 2022-04-12 | Novaliq Gmbh | Topical sunscreen formulation |
ES2974839T3 (es) | 2018-10-12 | 2024-07-01 | Novaliq Gmbh | Composición oftálmica para el tratamiento de la enfermedad de ojos secos |
WO2024108095A1 (en) * | 2022-11-17 | 2024-05-23 | Martin Coffey | Semifluorinated alkane antibiotic combination compositions for treatment of ocular disorders |
Family Cites Families (103)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US10022A (en) | 1853-09-13 | Lard-lamp | ||
US2616927A (en) | 1950-05-12 | 1952-11-04 | Minnesota Mining & Mfg | Fluorocarbon tertiary amines |
US4452818A (en) | 1982-03-19 | 1984-06-05 | Haidt Sterling J | Extraocular method of treating the eye with liquid perfluorocarbons |
US5077036A (en) | 1986-01-14 | 1991-12-31 | Alliance Pharmaceutical Corp. | Biocompatible stable fluorocarbon emulsions for contrast enhancement and oxygen transport comprising 40-125% wt./volume fluorocarbon combined with a phospholipid |
JPS6452722A (en) | 1987-05-01 | 1989-02-28 | Anjierini Pharmaceut Inc | Ophthalmic composition |
US5518731A (en) | 1990-09-27 | 1996-05-21 | Allergan, Inc. | Nonaqueous fluorinated drug delivery vehicle suspensions |
US6458376B1 (en) | 1990-09-27 | 2002-10-01 | Allergan, Inc. | Nonaqueous fluorinated drug delivery suspensions |
US5326566A (en) | 1991-05-17 | 1994-07-05 | Bristol-Myers Squibb Company | Use of dibutyl adipate and isopropyl myristate in topical and transdermal products |
GB9114374D0 (en) | 1991-07-03 | 1991-08-21 | Smithkline Beecham Plc | Novel process |
FR2679150A1 (fr) | 1991-07-17 | 1993-01-22 | Atta | Preparations comprenant un fluorocarbure ou compose hautement fluore et un compose organique lipophile-fluorophile, et leurs utilisations. |
US5336175A (en) | 1992-10-29 | 1994-08-09 | Mames Robert N | Method for the treatment of retinal detachments |
DE4405627A1 (de) | 1994-02-22 | 1995-08-24 | Hoechst Ag | Fluorkohlenwasserstoffe enthaltende Ölemulsionen |
FR2720943B1 (fr) | 1994-06-09 | 1996-08-23 | Applic Transferts Technolo | Emulsions inverses stables à forte concentration en composé(s) fluoré(s) et leur utilisation pour l'administration pulmonaire de médicaments et pour la fabrication d'émulsions multiples. |
US6294563B1 (en) | 1994-10-27 | 2001-09-25 | Allergan Sales, Inc. | Combinations of prostaglandins and brimonidine or derivatives thereof |
US5696164A (en) | 1994-12-22 | 1997-12-09 | Johnson & Johnson Consumer Products, Inc. | Antifungal treatment of nails |
US5874481A (en) | 1995-06-07 | 1999-02-23 | Alliance Pharmaceutical Corp. | Fluorochemical solutions for the delivery of lipophilic pharmaceutical agents |
US5667809A (en) * | 1995-06-07 | 1997-09-16 | Alliance Pharmaceutical Corp. | Continuous fluorochemical microdispersions for the delivery of lipophilic pharmaceutical agents |
DE19536504C2 (de) | 1995-09-29 | 1999-09-23 | H Meinert | Verwendung fluorierter Alkane |
US5874469A (en) | 1996-01-05 | 1999-02-23 | Alcon Laboratories, Inc. | Fluoroalkyl hydrocarbons for administering water insoluble or unstable drugs |
US5863560A (en) | 1996-09-11 | 1999-01-26 | Virotex Corporation | Compositions and methods for topical application of therapeutic agents |
IN184589B (es) | 1996-10-16 | 2000-09-09 | Alza Corp | |
DE19709704C2 (de) | 1997-03-10 | 1999-11-04 | Michael Georgieff | Verwendung einer flüssigen Präparation von Xenon zur intravenösen Verabreichung bei Einleitung und/oder Aufrechterhaltung der Anaesthesie |
US5980936A (en) | 1997-08-07 | 1999-11-09 | Alliance Pharmaceutical Corp. | Multiple emulsions comprising a hydrophobic continuous phase |
US5981607A (en) | 1998-01-20 | 1999-11-09 | Allergan | Emulsion eye drop for alleviation of dry eye related symptoms in dry eye patients and/or contact lens wearers |
PT983037E (pt) | 1998-02-09 | 2003-09-30 | Macrochem Corp | Verniz para unhas antifungico |
DE19861012A1 (de) | 1998-03-18 | 1999-09-30 | Pharm Pur Gmbh | Behandlungsmittel für die Ophthalmologie |
DE69912441T2 (de) | 1998-08-19 | 2004-08-19 | Skyepharma Canada Inc., Verdun | Injizierbare wässerige propofoldispersionen |
US6140374A (en) | 1998-10-23 | 2000-10-31 | Abbott Laboratories | Propofol composition |
US6159977A (en) | 1998-11-16 | 2000-12-12 | Astan, Inc. | Therapeutic anti-fungal nail preparation |
US7258869B1 (en) | 1999-02-08 | 2007-08-21 | Alza Corporation | Stable non-aqueous single phase viscous vehicles and formulations utilizing such vehicle |
NZ513441A (en) | 1999-02-08 | 2004-01-30 | Alza Corp | Stable non-aqueous single phase viscous drug delivery vehicles comprising a polymer a solvent and a surfactant |
WO2000054588A1 (en) | 1999-03-15 | 2000-09-21 | John Claude Krusz | Treatment of acute headaches and chronic pain using rapidly-cleared anesthetic drug at sub-anesthetic dosages |
US6177477B1 (en) | 1999-03-24 | 2001-01-23 | American Home Products Corporation | Propofol formulation containing TRIS |
US6239113B1 (en) * | 1999-03-31 | 2001-05-29 | Insite Vision, Incorporated | Topical treatment or prevention of ocular infections |
DE19926890C1 (de) | 1999-06-12 | 2000-07-27 | Pharm Pur Gmbh | Verwendung eines hochfluorierten oligomeren Alkans in der Ophthalmologie |
DE19938668B4 (de) | 1999-08-14 | 2006-01-26 | Bausch & Lomb Inc. | Tränenersatzmittel |
JP2001158734A (ja) | 1999-12-02 | 2001-06-12 | Lion Corp | 眼科用組成物及びソフトコンタクトレンズに対する吸着抑制方法 |
US20030018044A1 (en) | 2000-02-18 | 2003-01-23 | Peyman Gholam A. | Treatment of ocular disease |
DE10024413A1 (de) | 2000-05-19 | 2001-12-06 | Mika Pharma Gmbh | Pharmazeutische und/oder kosmetische Zubereitung |
US6399087B1 (en) | 2000-12-20 | 2002-06-04 | Amphastar Pharmaceuticals, Inc. | Propofol formulation with enhanced microbial inhibition |
CA2446060A1 (en) | 2001-05-07 | 2002-11-14 | Corium International | Compositions and delivery systems for administration of a local anesthetic agent |
US20040033228A1 (en) | 2002-08-16 | 2004-02-19 | Hans-Juergen Krause | Formulation of human antibodies for treating TNF-alpha associated disorders |
EP1645268A1 (en) | 2003-06-27 | 2006-04-12 | Wakunaga Pharmaceutical Co., Ltd. | Hard capsule |
US20050079210A1 (en) | 2003-10-09 | 2005-04-14 | Gupta Shyam K. | Liposomal delivery system for topical pharmaceutical, cosmeceutical, and cosmetic ingredients |
JP2007511616A (ja) | 2003-11-19 | 2007-05-10 | バーンズ−ジューイッシュ ホスピタル | 増強された薬物送達 |
GB0408164D0 (en) | 2004-04-13 | 2004-05-19 | Immune Targeting Systems Ltd | Antigen delivery vectors and constructs |
CA2563544A1 (en) * | 2004-04-19 | 2005-10-27 | Centre National De La Recherche Scientifique (C.N.R.S.) | Lung surfactant supplements |
MXPA06014425A (es) | 2004-06-08 | 2007-05-23 | Ocularis Pharma Inc | Composiciones oftalmicas hidrofobas y metodo de uso. |
US7063241B2 (en) | 2004-06-10 | 2006-06-20 | Allergan, Inc. | Dispensing tip |
KR20070040381A (ko) | 2004-07-01 | 2007-04-16 | 셰펜스 아이 리써치 | 눈의 장애 및 상태를 치료하는 조성물 및 방법 |
US20060078580A1 (en) | 2004-10-08 | 2006-04-13 | Mediquest Therapeutics, Inc. | Organo-gel formulations for therapeutic applications |
US7740875B2 (en) | 2004-10-08 | 2010-06-22 | Mediquest Therapeutics, Inc. | Organo-gel formulations for therapeutic applications |
EP1688161A1 (en) | 2004-11-02 | 2006-08-09 | Switch Biotech Aktiengesellschaft | Use of pirlindole for the treatment of diseases which are characterized by proliferation of t-lymphocytes and/or hyperproliferation of keratinocytes in particular atopic dermatitis and psoriasis |
GB0511499D0 (en) | 2005-06-06 | 2005-07-13 | Medpharm Ltd | Topical ungual formulations |
DE602006004887D1 (de) | 2005-08-05 | 2009-03-05 | Bharat Serums & Vaccines Ltd | Intravenöse propofol-emulsionszusammensetzungen mit konservierendem effekt |
FR2892023B1 (fr) | 2005-10-14 | 2009-09-25 | Galderma Sa | Composition pharmaceutique a base d'amorolfine et d'agent filmogene hydrosoluble pour application ungueale et peri-ungueale |
DE102005055811A1 (de) | 2005-11-23 | 2007-05-31 | Novaliq Gmbh | Verwendung einer Zusammensetzung zur Konservierung von Organen und Gliedmaßen |
TWI376239B (en) | 2006-02-01 | 2012-11-11 | Andrew Xian Chen | Vitamin e succinate stabilized pharmaceutical compositions, methods for the preparation and the use thereof |
JP5694664B2 (ja) | 2006-09-29 | 2015-04-01 | サーモディクス,インコーポレイティド | 生分解性眼用インプラント及び眼の病気を治療する方法 |
US9000048B2 (en) | 2006-11-28 | 2015-04-07 | Wisconsin Alumni Research Foundation | Fluoropolymer-based emulsions for the intravenous delivery of fluorinated volatile anesthetics |
WO2008068775A2 (en) | 2006-12-07 | 2008-06-12 | Sun Pharmaceutical Industries Limited | Metered drop bottle for dispensing microliter amounts of a liquid in the form of a drop |
ITMI20070890A1 (it) | 2007-05-04 | 2008-11-05 | Sifi Spa | Composizioni oftalmiche per il trattamento della ipertensione oculare e del glaucoma |
FR2918891B1 (fr) | 2007-07-20 | 2009-09-25 | Thea Sa Lab | Solution ophtalmique a base de prostaglandines sans conservateur |
US8222292B2 (en) | 2007-08-06 | 2012-07-17 | Insys Therapeutics, Inc. | Liquid cannabinoid formulations |
DE102007055046A1 (de) * | 2007-11-19 | 2009-05-28 | Fluoron Gmbh | Infusionslösung |
ES2377152T3 (es) | 2008-04-18 | 2012-03-22 | Novaliq Gmbh | Uso inhalativo e instilativo de alcanos semifluorados como vehículos de principios activos en la región intrapulmonar |
US20100006600A1 (en) | 2008-07-14 | 2010-01-14 | Dascanio Gustavo A | Fluid dispenser including hydrophobic ring |
EP2367527A2 (en) | 2008-11-26 | 2011-09-28 | SurModics, Inc. | Implantable ocular drug delivery device and methods |
US8501800B2 (en) * | 2009-03-05 | 2013-08-06 | Insite Vision Incorporated | Controlled-release ophthalmic vehicles |
IT1393419B1 (it) | 2009-03-19 | 2012-04-20 | Medivis S R L | Composizioni oftalmiche a base di acidi grassi polinsaturi omega-3 e omega-6. |
WO2010146536A1 (en) | 2009-06-18 | 2010-12-23 | Koninklijke Philips Electronics N.V. | Suspension of particles with drug |
JP5736635B2 (ja) | 2009-06-25 | 2015-06-17 | ライオン株式会社 | ドライアイ治療剤 |
US9012503B2 (en) | 2009-06-25 | 2015-04-21 | Lion Corporation | Ophthalmic composition |
CA2752849C (en) | 2009-07-24 | 2014-07-08 | Bernd G. Seigfried | Liquid compositions capable of foaming and including active agents, and methods for making or developing same |
JP2011024841A (ja) | 2009-07-28 | 2011-02-10 | 健太 ▲浜崎▼ | 点眼補助具 |
EP2332525A1 (en) | 2009-11-23 | 2011-06-15 | Novaliq GmbH | Pharmaceutical composition comprising propofol |
EP2335735A1 (en) | 2009-12-14 | 2011-06-22 | Novaliq GmbH | Pharmaceutical composition for treatment of dry eye syndrome |
US20110223208A1 (en) | 2010-03-09 | 2011-09-15 | Beth Hill | Non-Aqueous High Concentration Reduced Viscosity Suspension Formulations |
EP2547323B1 (en) | 2010-03-17 | 2016-01-27 | Novaliq GmbH | Pharmaceutical composition for treatment of increased intraocular pressure |
DE102010022567A1 (de) | 2010-06-02 | 2011-12-08 | Fluoron Gmbh | Zubereitung |
EP2444063A1 (en) | 2010-10-20 | 2012-04-25 | Novaliq GmbH | Liquid pharmaceutical compositions for the delivery of active ingredients |
EP2462921A1 (en) | 2010-11-11 | 2012-06-13 | Novaliq GmbH | Liquid pharmaceutical compositions for the treatment of a posterior eye disease |
TR201808752T4 (tr) | 2011-01-04 | 2018-07-23 | Novaliq Gmbh | Semiflorlanmış alkanları içeren o/w emülsiyonları. |
EP2714008B1 (en) | 2011-05-25 | 2016-12-14 | Novaliq GmbH | Pharmaceutical composition for administration to nails |
CA2834855C (en) | 2011-05-25 | 2020-12-29 | Novaliq Gmbh | Topical pharmaceutical composition based on semifluorinated alkanes |
DK2806886T3 (en) | 2012-01-23 | 2017-06-06 | Novaliq Gmbh | STABILIZED PROTEIN COMPOSITIONS BASED ON SEMIFLUORED ALKANES |
WO2013126602A1 (en) | 2012-02-21 | 2013-08-29 | Massachusetts Eye & Ear Infirmary | Inflammatory eye disorders |
US9878000B2 (en) | 2012-06-20 | 2018-01-30 | University Of Waterloo | Mucoadhesive nanoparticle composition comprising immunosuppresant and methods of use thereof |
AU2013314303B2 (en) | 2012-09-12 | 2018-01-18 | Novaliq Gmbh | Semifluorinated alkane compositions |
MX363182B (es) | 2012-09-12 | 2019-03-13 | Novaliq Gmbh | Composiciones que comprenden mezclas de alcanos semifluorados. |
KR20150095684A (ko) | 2012-12-18 | 2015-08-21 | 노파르티스 아게 | 히알루로난에 결합하는 펩티드 태그를 이용하는 조성물 및 방법 |
EP2783703A1 (en) | 2013-03-25 | 2014-10-01 | B. Braun Melsungen AG | Semifluorocarbon compound containing contrast agent |
JP6503349B2 (ja) | 2013-07-23 | 2019-04-17 | ノバリック ゲーエムベーハー | 安定化された抗体組成物 |
WO2015153469A1 (en) | 2014-03-31 | 2015-10-08 | Amcor Limited | Controlled release container |
EP2944324A1 (de) | 2014-05-13 | 2015-11-18 | LTS LOHMANN Therapie-Systeme AG | Verwendung von semifluorierten Alkanen in transdermalen therapeutischen Systemen |
GB2544213B (en) | 2014-08-13 | 2017-09-27 | Univ Florida | Preservative removal from eye drops |
EP3495023B1 (en) | 2015-09-30 | 2020-04-22 | Novaliq GmbH | Semifluorinated compounds and their compositions |
US11154513B2 (en) | 2015-09-30 | 2021-10-26 | Novaliq Gmbh | Semifluorinated compounds |
KR20190003997A (ko) | 2016-06-01 | 2019-01-10 | 해롤드 리차드 헬스트롬 | 부교감 신경제와 항교감 신경제를 이용한 안구 건조증의 치료 |
WO2017220625A1 (en) | 2016-06-23 | 2017-12-28 | Novaliq Gmbh | Topical administration method |
AU2017333420A1 (en) | 2016-09-28 | 2019-04-04 | Novaliq Gmbh | Compositions comprising a cannabinoid receptor binding ligand |
AU2017380769B2 (en) | 2016-12-22 | 2023-12-21 | Novaliq Gmbh | Compositions comprising tacrolimus for the treatment of intraocular inflammatory eye diseases |
BR112019012791A2 (pt) | 2016-12-23 | 2019-12-03 | Novaliq Gmbh | composição oftálmica para o tratamento da doença do olho seco |
-
2010
- 2010-10-20 EP EP10188242A patent/EP2444063A1/en not_active Withdrawn
-
2011
- 2011-10-18 JP JP2013534288A patent/JP5770297B2/ja active Active
- 2011-10-18 DK DK11770454.4T patent/DK2629754T3/en active
- 2011-10-18 KR KR1020137009743A patent/KR101773225B1/ko active IP Right Grant
- 2011-10-18 CA CA2813016A patent/CA2813016C/en active Active
- 2011-10-18 PL PL11770454T patent/PL2629754T3/pl unknown
- 2011-10-18 US US13/824,048 patent/US9757459B2/en active Active
- 2011-10-18 AU AU2011317673A patent/AU2011317673B2/en active Active
- 2011-10-18 CN CN201180049413.3A patent/CN103153281B/zh active Active
- 2011-10-18 ES ES11770454.4T patent/ES2528105T3/es active Active
- 2011-10-18 PT PT117704544T patent/PT2629754E/pt unknown
- 2011-10-18 WO PCT/EP2011/068141 patent/WO2012052418A1/en active Application Filing
- 2011-10-18 IN IN2524DEN2013 patent/IN2013DN02524A/en unknown
- 2011-10-18 MX MX2013003892A patent/MX2013003892A/es active IP Right Grant
- 2011-10-18 BR BR112013007473-6A patent/BR112013007473B1/pt active IP Right Grant
- 2011-10-18 EP EP11770454.4A patent/EP2629754B1/en active Active
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2013
- 2013-08-09 HK HK13109363.5A patent/HK1182010A1/xx unknown
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2017
- 2017-07-24 US US15/658,187 patent/US9968678B2/en active Active
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2018
- 2018-04-04 US US15/945,587 patent/US11160865B2/en active Active
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AU2011317673B2 (en) | 2014-07-17 |
PL2629754T3 (pl) | 2015-04-30 |
PT2629754E (pt) | 2015-02-04 |
ES2528105T3 (es) | 2015-02-04 |
US9757459B2 (en) | 2017-09-12 |
DK2629754T3 (en) | 2015-01-26 |
BR112013007473B1 (pt) | 2021-11-03 |
AU2011317673A1 (en) | 2013-04-11 |
CN103153281B (zh) | 2015-09-30 |
CA2813016A1 (en) | 2012-04-26 |
KR101773225B1 (ko) | 2017-09-12 |
EP2629754A1 (en) | 2013-08-28 |
US20130266652A1 (en) | 2013-10-10 |
HK1182010A1 (en) | 2013-11-22 |
JP2013540140A (ja) | 2013-10-31 |
EP2629754B1 (en) | 2014-11-05 |
US11160865B2 (en) | 2021-11-02 |
BR112013007473A2 (pt) | 2016-07-19 |
JP5770297B2 (ja) | 2015-08-26 |
EP2444063A1 (en) | 2012-04-25 |
CN103153281A (zh) | 2013-06-12 |
CA2813016C (en) | 2017-10-03 |
US20180008710A1 (en) | 2018-01-11 |
KR20130139925A (ko) | 2013-12-23 |
US9968678B2 (en) | 2018-05-15 |
IN2013DN02524A (es) | 2015-08-07 |
WO2012052418A1 (en) | 2012-04-26 |
US20180221485A1 (en) | 2018-08-09 |
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