BR112013007473A2 - composição farmacêutica líquida para a administração de ingredientes ativos - Google Patents

composição farmacêutica líquida para a administração de ingredientes ativos

Info

Publication number
BR112013007473A2
BR112013007473A2 BR112013007473A BR112013007473A BR112013007473A2 BR 112013007473 A2 BR112013007473 A2 BR 112013007473A2 BR 112013007473 A BR112013007473 A BR 112013007473A BR 112013007473 A BR112013007473 A BR 112013007473A BR 112013007473 A2 BR112013007473 A2 BR 112013007473A2
Authority
BR
Brazil
Prior art keywords
active ingredients
compositions
administration
pharmaceutical composition
liquid pharmaceutical
Prior art date
Application number
BR112013007473A
Other languages
English (en)
Other versions
BR112013007473B1 (pt
Inventor
Bastian Theisinger
Bernhard Gunther
Sonja Theisinger
Original Assignee
Novaliq Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novaliq Gmbh filed Critical Novaliq Gmbh
Publication of BR112013007473A2 publication Critical patent/BR112013007473A2/pt
Publication of BR112013007473B1 publication Critical patent/BR112013007473B1/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/24—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0043—Nose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0046—Ear
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Otolaryngology (AREA)
  • Dermatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dispersion Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

composição farmacêutica líquida para a administração de ingredientes ativos. a presente invenção propõe novas composições farmacêuticas à base de alcanos semifluorados que podem ser usados como veículo para uma ampla gama de ingredientes ativos. ingredientes ativos preferidos incluem substâncias farmacêuticas pouco solúveis em água e/ou hidroliticamente sensíveis. as composições são concebidas como suspensões e possuem propriedades físicas superiores que as tornam altamente úteis como sistemas de administração farmacêuticos. as composições podem ser administradas topicamente ao olho ou injetadas por via subcutânea ou intramuscular. a presente invenção propõe ainda kits que compreendem as referidas composições.
BR112013007473-6A 2010-10-20 2011-10-18 Composição farmacêutica líquida para a administração de ingredientes ativos BR112013007473B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP10188242A EP2444063A1 (en) 2010-10-20 2010-10-20 Liquid pharmaceutical compositions for the delivery of active ingredients
EP10188242.1 2010-10-20
PCT/EP2011/068141 WO2012052418A1 (en) 2010-10-20 2011-10-18 Liquid pharmaceutical composition for the delivery of active ingredients

Publications (2)

Publication Number Publication Date
BR112013007473A2 true BR112013007473A2 (pt) 2016-07-19
BR112013007473B1 BR112013007473B1 (pt) 2021-11-03

Family

ID=43608363

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112013007473-6A BR112013007473B1 (pt) 2010-10-20 2011-10-18 Composição farmacêutica líquida para a administração de ingredientes ativos

Country Status (16)

Country Link
US (3) US9757459B2 (pt)
EP (2) EP2444063A1 (pt)
JP (1) JP5770297B2 (pt)
KR (1) KR101773225B1 (pt)
CN (1) CN103153281B (pt)
AU (1) AU2011317673B2 (pt)
BR (1) BR112013007473B1 (pt)
CA (1) CA2813016C (pt)
DK (1) DK2629754T3 (pt)
ES (1) ES2528105T3 (pt)
HK (1) HK1182010A1 (pt)
IN (1) IN2013DN02524A (pt)
MX (1) MX2013003892A (pt)
PL (1) PL2629754T3 (pt)
PT (1) PT2629754E (pt)
WO (1) WO2012052418A1 (pt)

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US9757459B2 (en) 2017-09-12
DK2629754T3 (en) 2015-01-26
BR112013007473B1 (pt) 2021-11-03
AU2011317673A1 (en) 2013-04-11
CN103153281B (zh) 2015-09-30
CA2813016A1 (en) 2012-04-26
MX2013003892A (es) 2013-07-05
KR101773225B1 (ko) 2017-09-12
EP2629754A1 (en) 2013-08-28
US20130266652A1 (en) 2013-10-10
HK1182010A1 (en) 2013-11-22
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EP2629754B1 (en) 2014-11-05
US11160865B2 (en) 2021-11-02
JP5770297B2 (ja) 2015-08-26
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CN103153281A (zh) 2013-06-12
CA2813016C (en) 2017-10-03
US20180008710A1 (en) 2018-01-11
KR20130139925A (ko) 2013-12-23
US9968678B2 (en) 2018-05-15
IN2013DN02524A (pt) 2015-08-07
WO2012052418A1 (en) 2012-04-26
US20180221485A1 (en) 2018-08-09

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