EA201270683A1 - Составы в виде лиофилизированного кека - Google Patents
Составы в виде лиофилизированного кекаInfo
- Publication number
- EA201270683A1 EA201270683A1 EA201270683A EA201270683A EA201270683A1 EA 201270683 A1 EA201270683 A1 EA 201270683A1 EA 201270683 A EA201270683 A EA 201270683A EA 201270683 A EA201270683 A EA 201270683A EA 201270683 A1 EA201270683 A1 EA 201270683A1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- keka
- lyophilized
- compositions
- reconstituted
- injection
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 2
- GIIZNNXWQWCKIB-UHFFFAOYSA-N Serevent Chemical compound C1=C(O)C(CO)=CC(C(O)CNCCCCCCOCCCCC=2C=CC=CC=2)=C1 GIIZNNXWQWCKIB-UHFFFAOYSA-N 0.000 abstract 1
- 239000002537 cosmetic Substances 0.000 abstract 1
- 239000003085 diluting agent Substances 0.000 abstract 1
- MGNNYOODZCAHBA-GQKYHHCASA-N fluticasone Chemical compound C1([C@@H](F)C2)=CC(=O)C=C[C@]1(C)[C@]1(F)[C@@H]2[C@@H]2C[C@@H](C)[C@@](C(=O)SCF)(O)[C@@]2(C)C[C@@H]1O MGNNYOODZCAHBA-GQKYHHCASA-N 0.000 abstract 1
- 229960002714 fluticasone Drugs 0.000 abstract 1
- 238000002347 injection Methods 0.000 abstract 1
- 239000007924 injection Substances 0.000 abstract 1
- 238000007911 parenteral administration Methods 0.000 abstract 1
- 229960004017 salmeterol Drugs 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
- 238000010254 subcutaneous injection Methods 0.000 abstract 1
- 239000007929 subcutaneous injection Substances 0.000 abstract 1
- 239000000725 suspension Substances 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
- A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Diabetes (AREA)
- Emergency Medicine (AREA)
- Dermatology (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Child & Adolescent Psychology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Endocrinology (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Cosmetics (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Изобретение включает лиофилизированные формы на основе флутиказона, салметерола или их фармацевтически приемлемой соли или комбинации в виде кека, которые обеспечивают устойчивость при комнатной температуре в течение продолжительного периода времени. При восстановлении с помощью приемлемого растворителя (например, носителя или разбавителя) восстановленный фармацевтический или косметический состав представляет стерильную несуспензионную форму, пригодную для парентерального введения в виде инъекции, включая подкожную инъекцию.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US29564610P | 2010-01-15 | 2010-01-15 | |
US61/295,646 | 2010-01-15 | ||
PCT/US2011/021424 WO2011088413A2 (en) | 2010-01-15 | 2011-01-14 | Lyophilized cake formulations |
Publications (2)
Publication Number | Publication Date |
---|---|
EA201270683A1 true EA201270683A1 (ru) | 2013-06-28 |
EA028679B1 EA028679B1 (ru) | 2017-12-29 |
Family
ID=43736446
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EA201270683A EA028679B1 (ru) | 2010-01-15 | 2011-01-14 | Составы в виде лиофилизированного кека |
Country Status (14)
Country | Link |
---|---|
US (1) | US20110224176A1 (ru) |
EP (1) | EP2523667A4 (ru) |
JP (2) | JP2013517294A (ru) |
KR (2) | KR101638301B1 (ru) |
CN (1) | CN102869363A (ru) |
AU (1) | AU2011205646B2 (ru) |
BR (1) | BR112012017556A2 (ru) |
CA (1) | CA2786618C (ru) |
EA (1) | EA028679B1 (ru) |
GB (2) | GB2487868B (ru) |
IL (1) | IL220818A0 (ru) |
MX (1) | MX2012008171A (ru) |
SG (2) | SG182485A1 (ru) |
WO (1) | WO2011088413A2 (ru) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ATE552032T1 (de) | 2005-07-14 | 2012-04-15 | Lithera Inc | Verbesserte lipolytikum-formulierung mit hinhaltender wirkstofffreigabe für die arealbehandlung von fettgewebe |
JP2010506941A (ja) * | 2006-10-17 | 2010-03-04 | リセラ,インク. | 甲状腺眼症の治療のための方法、組成物及び製剤 |
US9132084B2 (en) * | 2009-05-27 | 2015-09-15 | Neothetics, Inc. | Methods for administration and formulations for the treatment of regional adipose tissue |
WO2012071480A2 (en) * | 2010-11-24 | 2012-05-31 | Lithera, Inc. | Lipophilic glucocorticosteroid monotherapeutic formulations and methods for the cosmetic treatment of adiposity and contour bulging |
TW201231042A (en) * | 2010-11-24 | 2012-08-01 | Lithera Inc | Selective, lipophilic, and long-acting beta agonist monotherapeutic formulations and methods for the cosmetic treatment of adiposity and contour bulging |
US8765725B2 (en) | 2012-05-08 | 2014-07-01 | Aciex Therapeutics, Inc. | Preparations of hydrophobic therapeutic agents, methods of manufacture and use thereof |
EP2847207B1 (en) | 2012-05-08 | 2019-03-27 | Nicox Ophthalmics, Inc. | Fluticasone propionate nanocrystals |
US9815865B2 (en) | 2013-01-07 | 2017-11-14 | Nicox Ophthalmics, Inc. | Preparations of hydrophobic therapeutic agents, methods of manufacture and use thereof |
US9078853B2 (en) * | 2013-06-18 | 2015-07-14 | Cmpd Licensing, Llc | Dry pharmaceutical compositions for topical delivery of oral medications, nasal delivery and to treat ear disorders |
CN107233217A (zh) * | 2016-03-25 | 2017-10-10 | 李和伟 | 一种含有表面活性剂的冻干制剂及其洗护产品 |
US10966946B2 (en) | 2016-11-17 | 2021-04-06 | Cmpd Licensing, Llc | Compounded compositions and methods for treating pain |
US10525025B2 (en) | 2016-11-17 | 2020-01-07 | Cmpd Licensing, Llc | Compounded compositions and methods for treating pain |
US9999604B2 (en) | 2016-11-17 | 2018-06-19 | Cmpd Licensing, Llc | Compounded solutions of diclofenac and lidocaine and methods |
US11737975B2 (en) | 2016-11-17 | 2023-08-29 | Cmpd Licensing, Llc | Compounded compositions and methods for treating pain |
US11986448B2 (en) | 2016-11-17 | 2024-05-21 | Cmpd Licensing, Llc | Compounded compositions and methods for treating pain |
JP7245301B1 (ja) | 2021-09-24 | 2023-03-23 | 浩義 井上 | エアフィルタ用塵埃捕捉剤、ならびにそれを用いたエアフィルタ |
Family Cites Families (83)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4525359A (en) * | 1982-12-10 | 1985-06-25 | Greenway Frank L Iii | Treatment for selective weight control |
GB8426672D0 (en) * | 1984-10-22 | 1984-11-28 | Erba Farmitalia | Pharmaceutical compositions |
JPH0696521B2 (ja) * | 1986-01-31 | 1994-11-30 | 千寿製薬株式会社 | 眼局所投与用眼圧降下剤 |
FR2602423B1 (fr) * | 1986-08-08 | 1989-05-05 | Ethypharm Sa | Procede de preparation d'un medicament a base de fenofibrate, medicament obtenu par ce procede |
US5270305A (en) * | 1989-09-08 | 1993-12-14 | Glaxo Group Limited | Medicaments |
CA2030174C (en) * | 1990-01-10 | 1996-12-24 | Anthony H. Cincotta | Process for the long term reduction of body fat stores, insulin resistance, hyperinsulinemia and hypoglycemia in vertebrates |
US5126147A (en) * | 1990-02-08 | 1992-06-30 | Biosearch, Inc. | Sustained release dosage form |
US5919827A (en) * | 1990-07-11 | 1999-07-06 | Sepracor Inc. | Method for treating asthma using optically pure R(-) salmeterol |
SE9302777D0 (sv) * | 1993-08-27 | 1993-08-27 | Astra Ab | Process for conditioning substances |
HU227519B1 (en) * | 1991-12-18 | 2011-07-28 | Astra Ab | Synergic pharmaceutical composition containing combination of formoterol and budesonide |
US5314916A (en) * | 1993-04-19 | 1994-05-24 | Alcon Laboratories, Inc. | B2 adrenegic agonists and use thereof in the treatment of glaucoma |
US6316443B1 (en) * | 1994-08-04 | 2001-11-13 | Merck & Co., Inc. | Ophthalmic compositions comprising combinations of a carbonic anhydrase inhibitor and a β-adrenergic antagonist |
GB9512854D0 (en) * | 1995-06-23 | 1995-08-23 | Wellcome Found | Novel formulation |
WO1997035882A1 (en) * | 1996-03-27 | 1997-10-02 | Ortho Pharmaceutical Corporation | Lyophilized pulmonary surfactant peptide compositions |
US5855913A (en) * | 1997-01-16 | 1999-01-05 | Massachusetts Instite Of Technology | Particles incorporating surfactants for pulmonary drug delivery |
WO1998010758A1 (en) * | 1996-09-13 | 1998-03-19 | The Regents Of The University Of California | Methods for treatment of retinal diseases |
SE9700135D0 (sv) * | 1997-01-20 | 1997-01-20 | Astra Ab | New formulation |
US6656508B2 (en) * | 1997-04-17 | 2003-12-02 | Amgen Inc. | Sustained-release alginate gels |
CA2286913C (en) * | 1997-04-30 | 2008-12-09 | Bridge Pharma, Inc. | Composition and methods using an eutomer |
US20010044584A1 (en) * | 1997-08-28 | 2001-11-22 | Kensey Kenneth R. | In vivo delivery methods and compositions |
SE9703407D0 (sv) * | 1997-09-19 | 1997-09-19 | Astra Ab | New use |
US20030095925A1 (en) * | 1997-10-01 | 2003-05-22 | Dugger Harry A. | Buccal, polar and non-polar spray or capsule containing drugs for treating metabolic disorders |
US6384259B1 (en) * | 1998-11-16 | 2002-05-07 | Medimmune Oncology, Inc. | Stable amorphous amifostine compositions and dosage form |
US20040208910A1 (en) * | 2000-04-26 | 2004-10-21 | Control Delivery Systems, Inc. | Sustained release device and method for ocular delivery of adrenergic agents |
GB0012260D0 (en) * | 2000-05-19 | 2000-07-12 | Astrazeneca Ab | Novel composition |
AUPQ797700A0 (en) * | 2000-06-06 | 2000-06-29 | Austin Research Institute, The | Vaccine |
GB0015981D0 (en) * | 2000-06-29 | 2000-08-23 | Glaxo Group Ltd | Novel process for preparing crystalline particles |
US6936426B2 (en) * | 2000-10-06 | 2005-08-30 | Harbor-Ucla Research And Education Institute | Detection of antibody mediated inflammatory auto-immune disorders |
FI20002215A0 (fi) * | 2000-10-06 | 2000-10-06 | Orion Yhtymae Oyj | Yhdistelmäpartikkelit |
FI20002216A0 (fi) * | 2000-10-06 | 2000-10-06 | Orion Yhtymae Oyj | Yhdistelmäpartikkelit astman hoitoon |
AU2002231697B2 (en) * | 2000-12-07 | 2006-09-07 | Enceladus Pharmaceuticals B.V. | Composition for treatment of inflammatory disorders |
US20030022856A1 (en) * | 2001-01-30 | 2003-01-30 | The Regents Of The University Of Michigan | Method for sustained release local delivery of drugs for ablation of unwanted tissue |
UA77656C2 (en) * | 2001-04-07 | 2007-01-15 | Glaxo Group Ltd | S-fluoromethyl ester of 6-alpha, 9-alpha-difluoro-17-alpha-[(2-furanylcarbonyl)oxy]-11-beta-hydroxy-16- alpha-methyl-3-oxoandrosta-1,4-dien-17-beta-carbothioacid as anti-inflammatory agent |
US20030055026A1 (en) * | 2001-04-17 | 2003-03-20 | Dey L.P. | Formoterol/steroid bronchodilating compositions and methods of use thereof |
MY137522A (en) * | 2001-04-30 | 2009-02-27 | Glaxo Group Ltd | Novel anti-inflammatory androstane derivatives. |
EP1438019A1 (en) * | 2001-10-24 | 2004-07-21 | PARI GmbH Spezialisten für effektive Inhalation | Kit for the preparation of a pharmaceutical composition |
US6625078B2 (en) * | 2002-02-11 | 2003-09-23 | United Memories, Inc. | Look-ahead refresh for an integrated circuit memory |
US8541399B2 (en) * | 2002-02-19 | 2013-09-24 | Resolution Chemicals Limited | Solvent-based sterilisation of pharmaceuticals |
US20050009798A1 (en) * | 2002-02-20 | 2005-01-13 | Sepracor Inc. | Carbonate and carbamate modified forms of glucocorticoids in combination with B2 adrenergic agonists |
US6800181B1 (en) * | 2003-03-12 | 2004-10-05 | Carlo L. Accattato | Device for cleaning jewelry |
US6643212B1 (en) * | 2002-04-18 | 2003-11-04 | United Memories, Inc. | Simultaneous function dynamic random access memory device technique |
US20040028545A1 (en) * | 2002-08-06 | 2004-02-12 | Ta-Chin Wang | Cylinder assembly for a mini air compressor |
US20040208833A1 (en) * | 2003-02-04 | 2004-10-21 | Elan Pharma International Ltd. | Novel fluticasone formulations |
US20040209850A1 (en) * | 2003-04-15 | 2004-10-21 | Theraquest Biosciences, Llc | Methods of treating pain and compositions for use therefor |
US9808471B2 (en) * | 2003-04-16 | 2017-11-07 | Mylan Specialty Lp | Nasal pharmaceutical formulations and methods of using the same |
WO2004103057A2 (en) * | 2003-05-15 | 2004-12-02 | The University Of Georgia Research Foundation, Inc. | Compositions and methods for inducing adipose tissue cell death |
SE0302029D0 (sv) * | 2003-07-07 | 2003-07-07 | Astrazeneca Ab | Novel process |
TWI359675B (en) * | 2003-07-10 | 2012-03-11 | Dey L P | Bronchodilating β-agonist compositions |
GB0316290D0 (en) * | 2003-07-11 | 2003-08-13 | Glaxo Group Ltd | Novel compounds |
JP2007508240A (ja) * | 2003-07-22 | 2007-04-05 | バクスター・インターナショナル・インコーポレイテッド | 低分子量有機分子の小球状粒子ならびにその調製方法および使用方法 |
BRPI0414907A (pt) * | 2003-09-30 | 2006-11-07 | Acusphere Inc | formulações farmacêuticas com liberação sustentada injetáveis, orais ou tópicas |
DE10347994A1 (de) * | 2003-10-15 | 2005-06-16 | Pari GmbH Spezialisten für effektive Inhalation | Wässrige Aerosol-Zubereitung |
AU2004287875B2 (en) * | 2003-11-05 | 2011-06-02 | Bausch + Lomb Ireland Limited | Modulators of cellular adhesion |
CN100551378C (zh) * | 2003-11-14 | 2009-10-21 | 千寿制药株式会社 | 包含氨基糖苷类抗生素和溴芬酸的水溶液制剂 |
WO2005051092A2 (en) * | 2003-11-20 | 2005-06-09 | Alteragon Pty Ltd | Method of decreasing fat deposits and body weight in mammals and birds |
KR100573828B1 (ko) * | 2003-12-29 | 2006-04-26 | 주식회사 하이닉스반도체 | 셀데이터의 손실을 방지하기 위한 반도체 메모리 소자 |
US20070020298A1 (en) * | 2003-12-31 | 2007-01-25 | Pipkin James D | Inhalant formulation containing sulfoalkyl ether gamma-cyclodextrin and corticosteroid |
CN1640390A (zh) * | 2004-01-17 | 2005-07-20 | 北京博尔达生物技术开发有限公司 | 注射用新鱼腥草素钠冻干粉针剂及制备方法 |
US7468428B2 (en) * | 2004-03-17 | 2008-12-23 | App Pharmaceuticals, Llc | Lyophilized azithromycin formulation |
US20050212152A1 (en) * | 2004-03-23 | 2005-09-29 | Reens Daniel J | System and method for humidifying homes and commercial sites |
US7754230B2 (en) * | 2004-05-19 | 2010-07-13 | The Regents Of The University Of California | Methods and related compositions for reduction of fat |
JP2008507532A (ja) * | 2004-07-21 | 2008-03-13 | セラヴァンス, インコーポレーテッド | ジアリールエーテルβ2アドレナリン作用性レセプターアゴニスト |
US8313763B2 (en) * | 2004-10-04 | 2012-11-20 | Tolmar Therapeutics, Inc. | Sustained delivery formulations of rapamycin compounds |
WO2006108176A2 (en) * | 2005-04-08 | 2006-10-12 | The Regents Of The University Of California | Wound healing composition |
CN1706501A (zh) * | 2005-05-27 | 2005-12-14 | 沈阳药科大学 | 亲脂性药物环糊精包合物的制备方法 |
ATE552032T1 (de) * | 2005-07-14 | 2012-04-15 | Lithera Inc | Verbesserte lipolytikum-formulierung mit hinhaltender wirkstofffreigabe für die arealbehandlung von fettgewebe |
CN101252842A (zh) * | 2005-07-14 | 2008-08-27 | 利波西拉公司 | 用于局部脂肪组织治疗的持续释放的增强性脂肪分解性制剂 |
US8158152B2 (en) * | 2005-11-18 | 2012-04-17 | Scidose Llc | Lyophilization process and products obtained thereby |
FR2893845B1 (fr) * | 2005-11-30 | 2010-10-29 | Galderma Sa | Composition sous forme de spray comprenant un corticoide et une phase huileuse |
EP1973523A2 (en) * | 2005-12-15 | 2008-10-01 | Acusphere, Inc. | Processes for making particle-based pharmaceutical formulations for pulmonary or nasal administration |
US20070178051A1 (en) * | 2006-01-27 | 2007-08-02 | Elan Pharma International, Ltd. | Sterilized nanoparticulate glucocorticosteroid formulations |
MX2008012794A (es) * | 2006-04-03 | 2008-10-15 | Teva Pharma | Microparticulas de farmacos. |
JP2010506941A (ja) * | 2006-10-17 | 2010-03-04 | リセラ,インク. | 甲状腺眼症の治療のための方法、組成物及び製剤 |
JP2010523501A (ja) * | 2007-04-04 | 2010-07-15 | セラテクノロジーズ インコーポレイティド | Ghrh分子の医薬製剤 |
TWI405590B (zh) * | 2007-04-06 | 2013-08-21 | Activus Pharma Co Ltd | 微粉碎化有機化合物粒子之製法 |
US20090208492A1 (en) * | 2007-06-14 | 2009-08-20 | Elan Pharmaceuticals, Inc. | Lyophilized Immunoglobulin Formulations and Methods of Preparation |
BRPI0814716A2 (pt) * | 2007-06-22 | 2015-02-24 | Dompe Spa | Comprimidos efervescentes para uso em inalação |
US8865692B2 (en) * | 2007-11-13 | 2014-10-21 | Meritage Pharma, Inc | Compositions for the treatment of gastrointestinal inflammation |
US7723392B2 (en) * | 2007-12-03 | 2010-05-25 | Bridge Pharma, Inc. | Use of RR/SR-ractopamine |
KR101184869B1 (ko) * | 2008-04-24 | 2012-09-20 | 이매틱스 바이오테크놀로지스 게엠베하 | 백신을 위한 인간 조직 적합성 항원(hla) 종류 i 또는 ii 분자에 결합하는 종양 관련 펩티드의 신규한 제형 |
JP2010111592A (ja) * | 2008-11-04 | 2010-05-20 | Aska Pharmaceutical Co Ltd | プロピオン酸フルチカゾンを含む局所投与剤 |
US9132084B2 (en) * | 2009-05-27 | 2015-09-15 | Neothetics, Inc. | Methods for administration and formulations for the treatment of regional adipose tissue |
TW201231042A (en) * | 2010-11-24 | 2012-08-01 | Lithera Inc | Selective, lipophilic, and long-acting beta agonist monotherapeutic formulations and methods for the cosmetic treatment of adiposity and contour bulging |
-
2011
- 2011-01-14 JP JP2012549145A patent/JP2013517294A/ja active Pending
- 2011-01-14 BR BR112012017556A patent/BR112012017556A2/pt not_active IP Right Cessation
- 2011-01-14 AU AU2011205646A patent/AU2011205646B2/en not_active Ceased
- 2011-01-14 MX MX2012008171A patent/MX2012008171A/es unknown
- 2011-01-14 GB GB1207749.1A patent/GB2487868B/en not_active Expired - Fee Related
- 2011-01-14 GB GB1100628A patent/GB2477030A/en not_active Withdrawn
- 2011-01-14 SG SG2012051421A patent/SG182485A1/en unknown
- 2011-01-14 SG SG2014014351A patent/SG2014014351A/en unknown
- 2011-01-14 KR KR1020157018454A patent/KR101638301B1/ko active IP Right Grant
- 2011-01-14 US US13/007,518 patent/US20110224176A1/en not_active Abandoned
- 2011-01-14 EA EA201270683A patent/EA028679B1/ru not_active IP Right Cessation
- 2011-01-14 KR KR1020127021302A patent/KR20120113267A/ko active Application Filing
- 2011-01-14 EP EP11733493.8A patent/EP2523667A4/en not_active Withdrawn
- 2011-01-14 WO PCT/US2011/021424 patent/WO2011088413A2/en active Application Filing
- 2011-01-14 CN CN2011800135588A patent/CN102869363A/zh active Pending
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2012
- 2012-07-08 IL IL220818A patent/IL220818A0/en unknown
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2015
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Also Published As
Publication number | Publication date |
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KR20150085136A (ko) | 2015-07-22 |
GB201207749D0 (en) | 2012-06-13 |
WO2011088413A2 (en) | 2011-07-21 |
AU2011205646A1 (en) | 2012-08-09 |
SG182485A1 (en) | 2012-08-30 |
EP2523667A2 (en) | 2012-11-21 |
GB2487868A (en) | 2012-08-08 |
EP2523667A4 (en) | 2014-04-02 |
JP2013517294A (ja) | 2013-05-16 |
US20110224176A1 (en) | 2011-09-15 |
CA2786618A1 (en) | 2011-07-21 |
MX2012008171A (es) | 2012-12-17 |
CA2786618C (en) | 2016-04-12 |
GB2477030A (en) | 2011-07-20 |
WO2011088413A3 (en) | 2011-11-10 |
GB2487868B (en) | 2014-12-10 |
KR101638301B1 (ko) | 2016-07-08 |
AU2011205646B2 (en) | 2014-10-02 |
JP2016000741A (ja) | 2016-01-07 |
KR20120113267A (ko) | 2012-10-12 |
CN102869363A (zh) | 2013-01-09 |
BR112012017556A2 (pt) | 2016-08-16 |
SG2014014351A (en) | 2014-07-30 |
GB201100628D0 (en) | 2011-03-02 |
IL220818A0 (en) | 2012-09-24 |
EA028679B1 (ru) | 2017-12-29 |
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