MX2012005023A - Metodos y composiciones para tratar cancer. - Google Patents

Metodos y composiciones para tratar cancer.

Info

Publication number
MX2012005023A
MX2012005023A MX2012005023A MX2012005023A MX2012005023A MX 2012005023 A MX2012005023 A MX 2012005023A MX 2012005023 A MX2012005023 A MX 2012005023A MX 2012005023 A MX2012005023 A MX 2012005023A MX 2012005023 A MX2012005023 A MX 2012005023A
Authority
MX
Mexico
Prior art keywords
compound
cancer
subject
bcr
cells
Prior art date
Application number
MX2012005023A
Other languages
English (en)
Spanish (es)
Inventor
William C Shakespeare
Weisheng Huang
Victor M Rivera
Timothy P Clackson
Rachel M Squillace
Joseph M Gozgit
Original Assignee
Ariad Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=43922622&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX2012005023(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Ariad Pharma Inc filed Critical Ariad Pharma Inc
Publication of MX2012005023A publication Critical patent/MX2012005023A/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/50Pyridazines; Hydrogenated pyridazines
    • A61K31/5025Pyridazines; Hydrogenated pyridazines ortho- or peri-condensed with heterocyclic ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
MX2012005023A 2009-10-30 2010-11-01 Metodos y composiciones para tratar cancer. MX2012005023A (es)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US25669009P 2009-10-30 2009-10-30
US25666909P 2009-10-30 2009-10-30
US26101409P 2009-11-13 2009-11-13
PCT/US2010/055016 WO2011053938A1 (en) 2009-10-30 2010-11-01 Methods and compositions for treating cancer

Publications (1)

Publication Number Publication Date
MX2012005023A true MX2012005023A (es) 2012-06-19

Family

ID=43922622

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2012005023A MX2012005023A (es) 2009-10-30 2010-11-01 Metodos y composiciones para tratar cancer.

Country Status (16)

Country Link
US (2) US20120316137A1 (https=)
EP (2) EP2493460A4 (https=)
JP (1) JP2013509444A (https=)
KR (1) KR20120115237A (https=)
CN (1) CN102770129A (https=)
AU (1) AU2010313152A1 (https=)
CA (1) CA2777128A1 (https=)
CL (1) CL2012001133A1 (https=)
CR (1) CR20120202A (https=)
EA (1) EA201290255A1 (https=)
IL (1) IL218987A0 (https=)
MX (1) MX2012005023A (https=)
NI (1) NI201200072A (https=)
PH (1) PH12012500809A1 (https=)
WO (1) WO2011053938A1 (https=)
ZA (1) ZA201202256B (https=)

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EA034598B1 (ru) 2005-12-23 2020-02-25 Ариад Фармасьютикалз, Инк. Применение бициклических гетероарильных соединений для лечения рака
JP6130391B2 (ja) 2011-11-23 2017-05-17 インテリカイン, エルエルシー Mtor阻害剤を使用する強化された治療レジメン
CN103570724B (zh) * 2012-07-27 2015-12-16 中国科学院广州生物医药与健康研究院 ponatinib 的合成方法
CN103845290A (zh) 2012-12-03 2014-06-11 曼丽国际有限公司 Umirolimus及其衍生物用于治疗癌症的用途
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AU2013204506B2 (en) * 2012-12-13 2016-05-05 Takeda Pharmaceuticals U.S.A., Inc. Crystalline forms of 3-(imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N-{4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl}benzamide mono hydrochloride
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US20140343282A1 (en) 2013-05-16 2014-11-20 Apicore, Llc Processes for making ponatinib and intermediates thereof
EP3016954B1 (en) * 2013-07-04 2018-10-31 Sandoz AG Crystalline forms of ponatinib hydrochloride
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WO2015085973A1 (en) * 2013-12-09 2015-06-18 Zentiva, K.S. Modifications of 3-(2-imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-n-[4-[(4-methyl-1-piperazinyl)methyl]-3-(trifluoromethyl)phenyl] benzamide hydrochloride salt
WO2015085972A1 (en) * 2013-12-09 2015-06-18 Zentiva, K.S. NOVEL SALTS OF 3-(2-IMIDAZO[1,2-b]PYRIDAZIN-3-YLETHYNYL)-4-METHYL-N-[4-[(4-METHYL- 1-PIPERAZINYL)METHYL]-3-(TRIFLUOROMETHYL)PHENYL] BENZAMIDE
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CN105267200A (zh) * 2014-07-01 2016-01-27 中国科学院上海有机化学研究所 一种黄酮类化合物的应用
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CN106236732A (zh) * 2016-08-31 2016-12-21 佛山市弘泰药物研发有限公司 一种依维莫司软胶囊的制备方法
EA201991197A1 (ru) * 2016-12-15 2020-01-13 Ариад Фармасьютикалз, Инк. БЕНЗИМИДАЗОЛЬНЫЕ СОЕДИНЕНИЯ В КАЧЕСТВЕ ИНГИБИТОРОВ c-Kit
CN108047230B (zh) * 2017-12-29 2020-04-17 深圳蓝新科技有限公司 帕纳替尼的制备方法
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CN109875999B (zh) * 2018-05-29 2022-07-12 上海交通大学医学院附属第九人民医院 泊那替尼在kit突变型恶性黑色素瘤中的应用
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WO2021225980A1 (en) * 2020-05-04 2021-11-11 Dna-Seq, Inc. Methods and systems for determination of an effective therapeutic regimen and drug discovery
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Also Published As

Publication number Publication date
JP2013509444A (ja) 2013-03-14
IL218987A0 (en) 2012-06-28
US20120316137A1 (en) 2012-12-13
WO2011053938A1 (en) 2011-05-05
CA2777128A1 (en) 2011-05-05
ZA201202256B (en) 2012-12-27
NI201200072A (es) 2012-08-20
CN102770129A (zh) 2012-11-07
US20130178622A1 (en) 2013-07-11
EP2493460A1 (en) 2012-09-05
PH12012500809A1 (en) 2012-11-26
CR20120202A (es) 2012-06-12
KR20120115237A (ko) 2012-10-17
CL2012001133A1 (es) 2013-08-02
EA201290255A1 (ru) 2013-04-30
AU2010313152A1 (en) 2012-04-19
EP2762142A1 (en) 2014-08-06
EP2493460A4 (en) 2013-04-24
WO2011053938A8 (en) 2011-08-11

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