MX2011011623A - Antagonistas del receptor tipo toll 3. - Google Patents

Antagonistas del receptor tipo toll 3.

Info

Publication number
MX2011011623A
MX2011011623A MX2011011623A MX2011011623A MX2011011623A MX 2011011623 A MX2011011623 A MX 2011011623A MX 2011011623 A MX2011011623 A MX 2011011623A MX 2011011623 A MX2011011623 A MX 2011011623A MX 2011011623 A MX2011011623 A MX 2011011623A
Authority
MX
Mexico
Prior art keywords
toll
receptor
antagonists
tlr3
antibody antagonists
Prior art date
Application number
MX2011011623A
Other languages
English (en)
Inventor
Mark Cunningham
Mateo Lani San
Raymond Sweet
Robert Rauchenberger
Yiqing Feng
Katharine Heeringa
Jinquan Luo
Fang Teng
Sheng-Jiun Wu
Robert T Sarisky
Mark Rutz
Alexey Teplyakov
Original Assignee
Janssen Biotech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US12/609,675 external-priority patent/US8409567B2/en
Application filed by Janssen Biotech Inc filed Critical Janssen Biotech Inc
Publication of MX2011011623A publication Critical patent/MX2011011623A/es

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2896—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against molecules with a "CD"-designation, not provided for elsewhere
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    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
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    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A—HUMAN NECESSITIES
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
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    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
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    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
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    • C07K14/475—Growth factors; Growth regulators
    • C—CHEMISTRY; METALLURGY
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    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/22—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • A—HUMAN NECESSITIES
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    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2299/00—Coordinates from 3D structures of peptides, e.g. proteins or enzymes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/52—Constant or Fc region; Isotype
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    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/55—Fab or Fab'
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    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C—CHEMISTRY; METALLURGY
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    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
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    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/94—Stability, e.g. half-life, pH, temperature or enzyme-resistance
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

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  • Health & Medical Sciences (AREA)
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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Virology (AREA)
  • Neurology (AREA)
  • Gastroenterology & Hepatology (AREA)
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  • Biomedical Technology (AREA)
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Abstract

Se describen los antagonistas de anticuerpos del receptor tipo toIl 3 (TLR3), los polinucleótidos que codifican los antagonistas de los anticuerpos del TLR3 o fragmentos de estos y los métodos de fabricación y uso de lo anteriormente descrito.
MX2011011623A 2009-04-29 2010-04-29 Antagonistas del receptor tipo toll 3. MX2011011623A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US17368609P 2009-04-29 2009-04-29
US12/609,675 US8409567B2 (en) 2008-10-31 2009-10-30 Toll-like receptor 3 antagonists
PCT/US2010/032964 WO2010127113A2 (en) 2009-04-29 2010-04-29 Toll-like receptor 3 antagonists

Publications (1)

Publication Number Publication Date
MX2011011623A true MX2011011623A (es) 2011-11-18

Family

ID=43032773

Family Applications (2)

Application Number Title Priority Date Filing Date
MX2011011623A MX2011011623A (es) 2009-04-29 2010-04-29 Antagonistas del receptor tipo toll 3.
MX2013005648A MX349056B (es) 2009-04-29 2010-04-29 Antagonistas del receptor tipo toll 3.

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Application Number Title Priority Date Filing Date
MX2013005648A MX349056B (es) 2009-04-29 2010-04-29 Antagonistas del receptor tipo toll 3.

Country Status (33)

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EP (2) EP3020822A1 (es)
JP (1) JP5727463B2 (es)
KR (2) KR20120040141A (es)
CN (1) CN102482699A (es)
AU (1) AU2010241581A1 (es)
BR (1) BRPI1016191A2 (es)
CA (1) CA2760525A1 (es)
CL (1) CL2011002703A1 (es)
CO (1) CO6450607A2 (es)
CR (1) CR20110642A (es)
DK (1) DK2425008T3 (es)
EA (1) EA021512B1 (es)
EC (1) ECSP11011428A (es)
ES (1) ES2556239T3 (es)
HK (1) HK1170536A1 (es)
HR (1) HRP20151352T1 (es)
HU (1) HUE028021T2 (es)
IL (1) IL215906A0 (es)
ME (1) ME02280B (es)
MX (2) MX2011011623A (es)
MY (1) MY180699A (es)
NI (1) NI201100187A (es)
NZ (1) NZ596036A (es)
PE (1) PE20121493A1 (es)
PL (1) PL2425008T3 (es)
PT (1) PT2425008E (es)
RS (1) RS54451B1 (es)
SG (1) SG175396A1 (es)
SI (1) SI2425008T1 (es)
SM (1) SMT201500293B (es)
UA (1) UA112282C2 (es)
WO (1) WO2010127113A2 (es)
ZA (1) ZA201108724B (es)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105601742A (zh) 2008-10-31 2016-05-25 詹森生物科技公司 Toll样受体3拮抗剂
US20130090457A1 (en) * 2008-10-31 2013-04-11 Janssen Biotech, Inc. Toll-Like Receptor 3 Antagonists for the Treatment of Metabolic and Cardiovascular Diseases
WO2011004028A2 (en) * 2009-07-10 2011-01-13 Innate Pharma Tlr3 binding agents
US20140065154A1 (en) * 2011-01-12 2014-03-06 Innate Pharma Tlr3 binding agents
CN103443124A (zh) * 2011-01-17 2013-12-11 诺沃—诺迪斯克有限公司 Il-21配体
NZ622260A (en) * 2011-09-12 2016-11-25 Janssen Biotech Inc Toll-like receptor 3 antagonists
AU2013269652B2 (en) * 2012-05-31 2017-07-06 Innate Pharma TLR3 binding agents
KR101878023B1 (ko) 2015-12-07 2018-07-16 현대자동차주식회사 차량용 전원 관리 시스템
CN113484526A (zh) * 2021-08-11 2021-10-08 上海迈晋生物医药科技有限公司 一种抗FcRn抗体或其抗原结合片段生物学活性的检测方法

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