SMT201500293B - Antagonisti del recettore toll-like 3 - Google Patents

Antagonisti del recettore toll-like 3

Info

Publication number
SMT201500293B
SMT201500293B SM201500293T SM201500293T SMT201500293B SM T201500293 B SMT201500293 B SM T201500293B SM 201500293 T SM201500293 T SM 201500293T SM 201500293 T SM201500293 T SM 201500293T SM T201500293 B SMT201500293 B SM T201500293B
Authority
SM
San Marino
Prior art keywords
toll
antagonists
receptor
Prior art date
Application number
SM201500293T
Other languages
English (en)
Inventor
Mark Cunningham
Mateo Lani San
Robert T Sarisky
Raymond W Sweet
Robert Rauchenberger
Mark Rutz
Yiqing Feng
Katharine Heeringa
Jinquan Luo
Fang Teng
Alexey V Teplyakov
Sheng-Jiun Wu
Original Assignee
Janssen Biotech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US12/609,675 external-priority patent/US8409567B2/en
Application filed by Janssen Biotech Inc filed Critical Janssen Biotech Inc
Publication of SMT201500293B publication Critical patent/SMT201500293B/it

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2896—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against molecules with a "CD"-designation, not provided for elsewhere
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    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
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    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
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    • A—HUMAN NECESSITIES
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
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    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
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    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
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    • C—CHEMISTRY; METALLURGY
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    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
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    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/22—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • A—HUMAN NECESSITIES
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    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2299/00—Coordinates from 3D structures of peptides, e.g. proteins or enzymes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/52—Constant or Fc region; Isotype
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/55—Fab or Fab'
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/94—Stability, e.g. half-life, pH, temperature or enzyme-resistance
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    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
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  • Biochemistry (AREA)
  • Biophysics (AREA)
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  • Gastroenterology & Hepatology (AREA)
  • Biomedical Technology (AREA)
  • Oncology (AREA)
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  • Zoology (AREA)
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  • Diabetes (AREA)
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  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
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SM201500293T 2009-04-29 2015-11-27 Antagonisti del recettore toll-like 3 SMT201500293B (it)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US17368609P 2009-04-29 2009-04-29
US12/609,675 US8409567B2 (en) 2008-10-31 2009-10-30 Toll-like receptor 3 antagonists
PCT/US2010/032964 WO2010127113A2 (en) 2009-04-29 2010-04-29 Toll-like receptor 3 antagonists

Publications (1)

Publication Number Publication Date
SMT201500293B true SMT201500293B (it) 2016-01-08

Family

ID=43032773

Family Applications (1)

Application Number Title Priority Date Filing Date
SM201500293T SMT201500293B (it) 2009-04-29 2015-11-27 Antagonisti del recettore toll-like 3

Country Status (33)

Country Link
EP (2) EP3020822A1 (it)
JP (1) JP5727463B2 (it)
KR (2) KR101758713B1 (it)
CN (1) CN102482699A (it)
AU (1) AU2010241581A1 (it)
BR (1) BRPI1016191A2 (it)
CA (1) CA2760525A1 (it)
CL (1) CL2011002703A1 (it)
CO (1) CO6450607A2 (it)
CR (1) CR20110642A (it)
DK (1) DK2425008T3 (it)
EA (1) EA021512B1 (it)
EC (1) ECSP11011428A (it)
ES (1) ES2556239T3 (it)
HK (1) HK1170536A1 (it)
HR (1) HRP20151352T1 (it)
HU (1) HUE028021T2 (it)
IL (1) IL215906A0 (it)
ME (1) ME02280B (it)
MX (2) MX349056B (it)
MY (1) MY180699A (it)
NI (1) NI201100187A (it)
NZ (1) NZ596036A (it)
PE (1) PE20121493A1 (it)
PL (1) PL2425008T3 (it)
PT (1) PT2425008E (it)
RS (1) RS54451B1 (it)
SG (1) SG175396A1 (it)
SI (1) SI2425008T1 (it)
SM (1) SMT201500293B (it)
UA (1) UA112282C2 (it)
WO (1) WO2010127113A2 (it)
ZA (1) ZA201108724B (it)

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Publication number Priority date Publication date Assignee Title
AU2009308763B2 (en) 2008-10-31 2017-03-09 Janssen Biotech, Inc. Toll-like receptor 3 antagonists
US20130090457A1 (en) * 2008-10-31 2013-04-11 Janssen Biotech, Inc. Toll-Like Receptor 3 Antagonists for the Treatment of Metabolic and Cardiovascular Diseases
EP2451844B1 (en) * 2009-07-10 2015-04-22 Innate Pharma Tlr3 binding agents
CA2824313A1 (en) * 2011-01-12 2012-07-19 Innate Pharma Tlr3 binding agents
EP2665750A1 (en) * 2011-01-17 2013-11-27 Novo Nordisk A/S Il-21 ligands
BR112014005786A2 (pt) * 2011-09-12 2017-03-28 Janssen Biotech Inc antagonistas do receptor do tipo toll 3 para o tratamento de doenças metabólicas e cardiovasculares
US9944712B2 (en) 2012-05-31 2018-04-17 Innate Pharma TLR3 binding agents
KR101878023B1 (ko) 2015-12-07 2018-07-16 현대자동차주식회사 차량용 전원 관리 시스템
CN113484526A (zh) * 2021-08-11 2021-10-08 上海迈晋生物医药科技有限公司 一种抗FcRn抗体或其抗原结合片段生物学活性的检测方法

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US4683195A (en) 1986-01-30 1987-07-28 Cetus Corporation Process for amplifying, detecting, and/or-cloning nucleic acid sequences
US5225539A (en) 1986-03-27 1993-07-06 Medical Research Council Recombinant altered antibodies and methods of making altered antibodies
GB9015198D0 (en) 1990-07-10 1990-08-29 Brien Caroline J O Binding substance
US6407213B1 (en) 1991-06-14 2002-06-18 Genentech, Inc. Method for making humanized antibodies
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