MX2010009995A - Heterociclos puenteados como inhibidores de la integrasa del virus de inmunodeficiencia humana. - Google Patents

Heterociclos puenteados como inhibidores de la integrasa del virus de inmunodeficiencia humana.

Info

Publication number
MX2010009995A
MX2010009995A MX2010009995A MX2010009995A MX2010009995A MX 2010009995 A MX2010009995 A MX 2010009995A MX 2010009995 A MX2010009995 A MX 2010009995A MX 2010009995 A MX2010009995 A MX 2010009995A MX 2010009995 A MX2010009995 A MX 2010009995A
Authority
MX
Mexico
Prior art keywords
hiv integrase
integrase inhibitors
hiv
bridged heterocycles
treating
Prior art date
Application number
MX2010009995A
Other languages
English (en)
Spanish (es)
Inventor
Yasutsugu Ueda
Francis Beaulieu
Chen Li
Michael A Walker
Timothy P Connolly
B Narasimhulu Naidu
Carl Ouellet
Margaret E Sorenson
Manoj Patel
Nicholas A Meanwell
Kevin M Peese
Jonathan R Weiss
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Publication of MX2010009995A publication Critical patent/MX2010009995A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D498/18—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/08—Bridged systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/18—Bridged systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/08—Bridged systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/12—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains three hetero rings
    • C07D493/18—Bridged systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • AIDS & HIV (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
MX2010009995A 2008-03-19 2009-03-19 Heterociclos puenteados como inhibidores de la integrasa del virus de inmunodeficiencia humana. MX2010009995A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US3772908P 2008-03-19 2008-03-19
US12/406,268 US8129398B2 (en) 2008-03-19 2009-03-18 HIV integrase inhibitors
PCT/US2009/037596 WO2009117540A1 (en) 2008-03-19 2009-03-19 Bridged heterocycles as hiv integrase inhibitors

Publications (1)

Publication Number Publication Date
MX2010009995A true MX2010009995A (es) 2010-09-30

Family

ID=40863725

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2010009995A MX2010009995A (es) 2008-03-19 2009-03-19 Heterociclos puenteados como inhibidores de la integrasa del virus de inmunodeficiencia humana.

Country Status (15)

Country Link
US (1) US8129398B2 (https=)
EP (1) EP2280981B8 (https=)
JP (1) JP2011515412A (https=)
KR (1) KR20100137522A (https=)
CN (1) CN102036996A (https=)
AU (1) AU2009225577A1 (https=)
BR (1) BRPI0910307A2 (https=)
CA (1) CA2718950A1 (https=)
CO (1) CO6331439A2 (https=)
EA (1) EA201001508A1 (https=)
IL (1) IL208068A0 (https=)
MX (1) MX2010009995A (https=)
NZ (1) NZ588031A (https=)
WO (1) WO2009117540A1 (https=)
ZA (1) ZA201006589B (https=)

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US8283366B2 (en) 2010-01-22 2012-10-09 Ambrilia Biopharma, Inc. Derivatives of pyridoxine for inhibiting HIV integrase
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US9012491B2 (en) 2011-08-31 2015-04-21 Rempex Pharmaceuticals, Inc. Heterocyclic boronic acid ester derivatives and therapeutic uses thereof
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ES2859102T3 (es) 2013-07-12 2021-10-01 Gilead Sciences Inc Compuestos de carbamoilpiridona policíclica y su uso para el tratamiento de infecciones por VIH
CN103601613B (zh) * 2013-11-19 2015-07-08 浙江林江化工股份有限公司 一种3,4,5-三氟溴苯的制备方法
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Also Published As

Publication number Publication date
US20090253677A1 (en) 2009-10-08
CO6331439A2 (es) 2011-10-20
EP2280981A1 (en) 2011-02-09
WO2009117540A1 (en) 2009-09-24
CA2718950A1 (en) 2009-09-24
CN102036996A (zh) 2011-04-27
ZA201006589B (en) 2012-02-29
AU2009225577A1 (en) 2009-09-24
EA201001508A1 (ru) 2011-04-29
JP2011515412A (ja) 2011-05-19
IL208068A0 (en) 2010-12-30
KR20100137522A (ko) 2010-12-30
NZ588031A (en) 2011-12-22
EP2280981B1 (en) 2014-04-23
US8129398B2 (en) 2012-03-06
EP2280981B8 (en) 2014-09-17
BRPI0910307A2 (pt) 2019-09-24

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