MX2010009824A - Preparacion solida de desintegracion oral. - Google Patents
Preparacion solida de desintegracion oral.Info
- Publication number
- MX2010009824A MX2010009824A MX2010009824A MX2010009824A MX2010009824A MX 2010009824 A MX2010009824 A MX 2010009824A MX 2010009824 A MX2010009824 A MX 2010009824A MX 2010009824 A MX2010009824 A MX 2010009824A MX 2010009824 A MX2010009824 A MX 2010009824A
- Authority
- MX
- Mexico
- Prior art keywords
- orally
- solid preparation
- disintegrating solid
- fine granules
- active ingredient
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2886—Dragees; Coated pills or tablets, e.g. with film or compression coating having two or more different drug-free coatings; Tablets of the type inert core-drug layer-inactive layer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
- A61K9/2081—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets with microcapsules or coated microparticles according to A61K9/50
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
- A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Zoology (AREA)
- Physiology (AREA)
- Nutrition Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
La presente invención provee una preparación sólida de desintegración oral tal como un comprimido producido formando comprimidos los gránulos finos que muestran una liberación controlada de un ingrediente farmacéuticamente activo y un aditivo, y similares, y la preparación sólida de desintegración oral que contiene gránulos finos recubiertos con una capa de recubrimiento que contiene un polímero que produce una película de recubrimiento que tiene una elongación en la ruptura de alrededor de 100 a alrededor de 700. Con la preparación, la ruptura de los gránulos finos durante la formación del comprimido puede suprimirse en la producción de una preparación sólida de desintegración oral que contiene los gránulos finos que muestran una liberación controlada de un ingrediente activo desde el punto de vista farmacéutico.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2008061673 | 2008-03-11 | ||
JP2008334920 | 2008-12-26 | ||
PCT/JP2009/054983 WO2009113703A2 (en) | 2008-03-11 | 2009-03-10 | Orally-disintegrating solid preparation |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2010009824A true MX2010009824A (es) | 2010-09-28 |
Family
ID=40791576
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2010009824A MX2010009824A (es) | 2008-03-11 | 2009-03-10 | Preparacion solida de desintegracion oral. |
Country Status (26)
Country | Link |
---|---|
US (2) | US9241910B2 (es) |
EP (1) | EP2254556A2 (es) |
JP (1) | JP5604304B2 (es) |
KR (1) | KR20100129761A (es) |
CN (2) | CN102026627B (es) |
AR (1) | AR070863A1 (es) |
AU (1) | AU2009224254A1 (es) |
BR (1) | BRPI0909439A2 (es) |
CA (1) | CA2717947C (es) |
CL (1) | CL2009000557A1 (es) |
CO (1) | CO6321224A2 (es) |
CR (1) | CR11709A (es) |
DO (1) | DOP2010000273A (es) |
EA (1) | EA021792B1 (es) |
EC (1) | ECSP10010538A (es) |
GE (1) | GEP20135845B (es) |
IL (1) | IL207989A0 (es) |
MA (1) | MA32174B1 (es) |
MX (1) | MX2010009824A (es) |
MY (1) | MY173730A (es) |
NZ (1) | NZ588407A (es) |
PE (2) | PE20091620A1 (es) |
TW (1) | TWI441658B (es) |
UY (1) | UY31698A (es) |
WO (1) | WO2009113703A2 (es) |
ZA (1) | ZA201006679B (es) |
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NZ588407A (en) | 2008-03-11 | 2012-07-27 | Takeda Pharmaceutical | Orally-disintegrating solid preparation |
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EP3031451B1 (en) * | 2009-01-26 | 2018-03-07 | Shin-Etsu Chemical Co., Ltd | Wet granulation tableting method using aqueous dispersion of low-substituted hydroxypropyl cellulose |
EP2319504A1 (en) * | 2009-11-07 | 2011-05-11 | Laboratorios Del. Dr. Esteve, S.A. | Pharmaceutical solid dosage form |
US20130216617A1 (en) * | 2010-06-29 | 2013-08-22 | Cadila Healthcare Limited | Pharmaceutical compositions of (r)-lansoprazole |
UY33841A (es) * | 2010-12-27 | 2012-07-31 | Takeda Pharmaceutical | Comprimido de desintegracion oral |
CN102716097A (zh) * | 2012-05-29 | 2012-10-10 | 浙江华海药业股份有限公司 | 控制口腔崩解片药物释放速率的方法 |
FI126168B (en) | 2012-09-18 | 2016-07-29 | Novaldmedical Ltd Oy | A method for coating pharmaceutical substrates |
US10195153B2 (en) | 2013-08-12 | 2019-02-05 | Pharmaceutical Manufacturing Research Services, Inc. | Extruded immediate release abuse deterrent pill |
US9492444B2 (en) | 2013-12-17 | 2016-11-15 | Pharmaceutical Manufacturing Research Services, Inc. | Extruded extended release abuse deterrent pill |
US10172797B2 (en) | 2013-12-17 | 2019-01-08 | Pharmaceutical Manufacturing Research Services, Inc. | Extruded extended release abuse deterrent pill |
ES2809458T3 (es) | 2014-07-17 | 2021-03-04 | Pharmaceutical Manufacturing Res Services Inc | Forma de dosificación llena de líquido, disuasoria del abuso y de liberación inmediata |
AU2015336065A1 (en) | 2014-10-20 | 2017-05-04 | Pharmaceutical Manufacturing Research Services, Inc. | Extended release abuse deterrent liquid fill dosage form |
JP6371866B2 (ja) * | 2015-02-10 | 2018-08-08 | 富士フイルム株式会社 | 口腔内崩壊錠及びその製造方法 |
WO2016174664A1 (en) | 2015-04-29 | 2016-11-03 | Dexcel Pharma Technologies Ltd. | Orally disintegrating compositions |
WO2017146052A1 (ja) * | 2016-02-23 | 2017-08-31 | ニプロ株式会社 | 医薬組成物粒子とそれを含む口腔内崩壊製剤、医薬組成物粒子の製造方法 |
GB201607548D0 (en) * | 2016-04-29 | 2016-06-15 | Univ Central Lancashire | Solid dosage form |
US10076494B2 (en) | 2016-06-16 | 2018-09-18 | Dexcel Pharma Technologies Ltd. | Stable orally disintegrating pharmaceutical compositions |
JOP20190008A1 (ar) | 2016-07-26 | 2019-01-24 | Purdue Pharma Lp | علاج ومنع اضطرابات النوم |
US20190336476A1 (en) * | 2016-12-28 | 2019-11-07 | Fujifilm Toyama Chemical Co., Ltd. | Pharmaceutical composition |
KR102555664B1 (ko) * | 2017-02-21 | 2023-07-18 | 이에이 파마 가부시키가이샤 | 과립 제제 |
JP7235193B2 (ja) * | 2017-04-26 | 2023-03-08 | 大正製薬株式会社 | 固形組成物 |
JP7009288B2 (ja) * | 2017-05-18 | 2022-01-25 | エルメッド株式会社 | 湿製錠剤の製造方法及び湿製錠剤の品質向上方法 |
JP7336187B2 (ja) * | 2017-11-30 | 2023-08-31 | 日本ケミファ株式会社 | 多層構造を有する粒子状医薬組成物 |
CN111712235A (zh) | 2018-01-16 | 2020-09-25 | 应用材料公司 | 金属氧化物包封的药物组合物及其制备方法 |
WO2019145850A1 (en) | 2018-01-24 | 2019-08-01 | Purdue Pharma L. P. | Sleep disorder treatment and prevention |
CN111836618A (zh) * | 2018-02-08 | 2020-10-27 | 景凱生物科技股份有限公司 | 类阿片受体拮抗剂的固体剂型用的医药剂型 |
AU2020213989B2 (en) | 2019-01-31 | 2023-06-15 | Purdue Pharma L.P. | Polymorphic forms of a substituted-quinoxaline-type bridged-piperidine compound |
GB202001237D0 (en) * | 2020-01-29 | 2020-03-11 | Sisteks D O O | Granular pharmaceutical product for oral administration from a pre-filled straw and method of manufacturing such pharmaceutical product |
IL295007A (en) | 2020-01-31 | 2022-09-01 | Nanocopoeia Llc | Amorphous nilotinib microparticles and uses thereof |
WO2021222739A1 (en) | 2020-04-30 | 2021-11-04 | Nanocopoeia, Llc | Orally disintegrating tablet comprising amorphous solid dispersion of nilotinib |
TW202216124A (zh) | 2020-10-02 | 2022-05-01 | 美商應用材料股份有限公司 | 製備氧化矽塗佈藥品的低溫處理 |
CN112121067A (zh) * | 2020-11-16 | 2020-12-25 | 深圳科兴药业有限公司 | 一种婴儿型双歧杆菌微胶囊及其制备方法 |
CN117500923A (zh) | 2021-04-07 | 2024-02-02 | 巴特尔纪念研究院 | 用于鉴定和使用非病毒载体的快速设计、构建、测试和学习技术 |
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NZ588407A (en) | 2008-03-11 | 2012-07-27 | Takeda Pharmaceutical | Orally-disintegrating solid preparation |
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UY33841A (es) | 2010-12-27 | 2012-07-31 | Takeda Pharmaceutical | Comprimido de desintegracion oral |
-
2009
- 2009-03-10 NZ NZ588407A patent/NZ588407A/en not_active IP Right Cessation
- 2009-03-10 AU AU2009224254A patent/AU2009224254A1/en not_active Abandoned
- 2009-03-10 PE PE2009000349A patent/PE20091620A1/es not_active Application Discontinuation
- 2009-03-10 CA CA2717947A patent/CA2717947C/en active Active
- 2009-03-10 KR KR1020107022551A patent/KR20100129761A/ko not_active Application Discontinuation
- 2009-03-10 MX MX2010009824A patent/MX2010009824A/es not_active Application Discontinuation
- 2009-03-10 PE PE2014000364A patent/PE20141034A1/es not_active Application Discontinuation
- 2009-03-10 EA EA201071054A patent/EA021792B1/ru not_active IP Right Cessation
- 2009-03-10 MY MYPI2010004253A patent/MY173730A/en unknown
- 2009-03-10 AR ARP090100842A patent/AR070863A1/es unknown
- 2009-03-10 US US12/921,731 patent/US9241910B2/en active Active
- 2009-03-10 CL CL2009000557A patent/CL2009000557A1/es unknown
- 2009-03-10 GE GEAP2009011969 patent/GEP20135845B/en unknown
- 2009-03-10 CN CN200980116971.XA patent/CN102026627B/zh not_active Expired - Fee Related
- 2009-03-10 UY UY0001031698A patent/UY31698A/es not_active Application Discontinuation
- 2009-03-10 WO PCT/JP2009/054983 patent/WO2009113703A2/en active Application Filing
- 2009-03-10 EP EP09720410A patent/EP2254556A2/en not_active Withdrawn
- 2009-03-10 BR BRPI0909439A patent/BRPI0909439A2/pt not_active Application Discontinuation
- 2009-03-10 CN CN201410370293.2A patent/CN104127368A/zh active Pending
- 2009-03-10 TW TW098107630A patent/TWI441658B/zh not_active IP Right Cessation
- 2009-03-10 JP JP2010536259A patent/JP5604304B2/ja not_active Expired - Fee Related
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2010
- 2010-09-05 IL IL207989A patent/IL207989A0/en unknown
- 2010-09-10 DO DO2010000273A patent/DOP2010000273A/es unknown
- 2010-09-17 ZA ZA2010/06679A patent/ZA201006679B/en unknown
- 2010-09-29 MA MA33210A patent/MA32174B1/fr unknown
- 2010-09-30 CR CR11709A patent/CR11709A/es unknown
- 2010-10-11 CO CO10125889A patent/CO6321224A2/es not_active Application Discontinuation
- 2010-10-11 EC EC2010010538A patent/ECSP10010538A/es unknown
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2014
- 2014-10-21 US US14/519,979 patent/US20150037423A1/en not_active Abandoned
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