WO2011049309A3 - 속효성과 지속성을 동시에 갖는 약제학적 조성물 - Google Patents

속효성과 지속성을 동시에 갖는 약제학적 조성물 Download PDF

Info

Publication number
WO2011049309A3
WO2011049309A3 PCT/KR2010/006910 KR2010006910W WO2011049309A3 WO 2011049309 A3 WO2011049309 A3 WO 2011049309A3 KR 2010006910 W KR2010006910 W KR 2010006910W WO 2011049309 A3 WO2011049309 A3 WO 2011049309A3
Authority
WO
WIPO (PCT)
Prior art keywords
immediate
extended release
pharmaceutical composition
release portion
release characteristics
Prior art date
Application number
PCT/KR2010/006910
Other languages
English (en)
French (fr)
Other versions
WO2011049309A2 (ko
Inventor
오동준
김병기
문병관
유지석
신대희
류병환
Original Assignee
영진약품공업 주식회사
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 영진약품공업 주식회사 filed Critical 영진약품공업 주식회사
Priority to JP2012533089A priority Critical patent/JP5827952B2/ja
Priority to EP10825134.9A priority patent/EP2486918A4/en
Priority to CN201080045422.0A priority patent/CN102548544B/zh
Publication of WO2011049309A2 publication Critical patent/WO2011049309A2/ko
Priority to US13/108,050 priority patent/US9180101B2/en
Publication of WO2011049309A3 publication Critical patent/WO2011049309A3/ko

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5084—Mixtures of one or more drugs in different galenical forms, at least one of which being granules, microcapsules or (coated) microparticles according to A61K9/16 or A61K9/50, e.g. for obtaining a specific release pattern or for combining different drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Inorganic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

본 발명은 속효성과 지속성을 동시에 갖는 약제학적 조성물에 관한 것으로, 수불용성 폴리머로 표면 도포되어 있고, 약학적 활성 성분, 방출제어 기제와 약학적 허용 담체를 포함하는 서방부 및 약학적 활성 성분과 약학적 허용 담체를 포함하는 속방부를 포함하는 약제학적 조성물에 관한 것이다. 본 발명의 약제학적 조성물은 약학적 활성 성분, 방출 제어 기제와 약학적 허용 담체를 포함하는 서방부의 표면을 수불용성 폴리머로 도포함으로서 속방부와 분리하여 속방부와 서방부가 독립적인 방출특성을 나타내고, 사용 가능한 약학적 활성 성분의 함량과 종류에 제한이 없으면서 비교적 간단한 공정으로 제조될 수 있다.
PCT/KR2010/006910 2009-10-09 2010-10-08 속효성과 지속성을 동시에 갖는 약제학적 조성물 WO2011049309A2 (ko)

Priority Applications (4)

Application Number Priority Date Filing Date Title
JP2012533089A JP5827952B2 (ja) 2009-10-09 2010-10-08 速効性と持続性を同時に有する薬剤学的組成物
EP10825134.9A EP2486918A4 (en) 2009-10-09 2010-10-08 PHARMACEUTICAL COMPOSITION WITH BOTH IMMEDIATE AND DELAYED RELEASE
CN201080045422.0A CN102548544B (zh) 2009-10-09 2010-10-08 同时具有速效特性和长效特性的药物组合物
US13/108,050 US9180101B2 (en) 2009-10-09 2011-05-16 Pharmaceutical composition simultaneously having rapid-acting property and long-acting property

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
KR10-2009-0096315 2009-10-09
KR20090096315 2009-10-09
KR10-2009-0104248 2009-10-30
KR20090104248 2009-10-30

Related Child Applications (1)

Application Number Title Priority Date Filing Date
US13/108,050 Continuation US9180101B2 (en) 2009-10-09 2011-05-16 Pharmaceutical composition simultaneously having rapid-acting property and long-acting property

Publications (2)

Publication Number Publication Date
WO2011049309A2 WO2011049309A2 (ko) 2011-04-28
WO2011049309A3 true WO2011049309A3 (ko) 2011-10-13

Family

ID=43900777

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/KR2010/006910 WO2011049309A2 (ko) 2009-10-09 2010-10-08 속효성과 지속성을 동시에 갖는 약제학적 조성물

Country Status (6)

Country Link
US (1) US9180101B2 (ko)
EP (1) EP2486918A4 (ko)
JP (1) JP5827952B2 (ko)
KR (1) KR101573889B1 (ko)
CN (1) CN102548544B (ko)
WO (1) WO2011049309A2 (ko)

Families Citing this family (57)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2012154174A1 (en) * 2011-05-10 2012-11-15 Liu Chui Yu Methods for treating insomnia
US9585862B2 (en) * 2011-05-20 2017-03-07 Sk Chemicals Co., Ltd. Patch containing rivastigmine
KR101257919B1 (ko) 2011-07-14 2013-04-30 주식회사 바이오파마티스 콜린 알포세레이트 또는 이의 약학적으로 허용되는 염을 포함하는 경구용 고형 제제 및 이의 제조방법
KR101257918B1 (ko) * 2011-07-14 2013-04-30 주식회사 바이오파마티스 콜린 알포세레이트 또는 이의 약학적으로 허용되는 염을 포함하는 서방형 약학 조성물 및 이의 제조방법
ES2586057T3 (es) * 2011-07-26 2016-10-11 Yuhan Corporation Comprimido de liberación sostenida que comprende pregabalina a través de un sistema de control de la liberación de dos fases
CA2852417A1 (en) 2011-10-21 2013-04-25 Takeda Pharmaceutical Company Limited Sustained-release preparation
US9358204B2 (en) * 2012-02-08 2016-06-07 Supernus Pharmaceuticals, Inc. Formulations of viloxazine
WO2013142314A1 (en) * 2012-03-19 2013-09-26 Althera Life Sciences, Llc Oral tablet formulation consisting of immediate release rosuv astatin and extended release metformin
SG11201405198YA (en) 2012-03-30 2014-09-26 Dae Woong Pharma Pharmaceutical composition comprising olmesartan medoxomil and rosuvastatin or its salt
HUE036187T2 (hu) * 2012-04-30 2018-06-28 Tillotts Pharma Ag Késleltetett leadású gyógyszerkészítmény
KR101397343B1 (ko) 2012-06-12 2014-05-19 씨제이제일제당 (주) 메트포르민 및 ＨＭＧ―ＣｏＡ 환원효소 억제제를 포함하는 약제학적 복합제제
KR20140013436A (ko) * 2012-07-24 2014-02-05 한미약품 주식회사 메트포르민 및 로수바스타틴을 포함하는 경구용 복합 제제
KR101469326B1 (ko) * 2012-10-24 2014-12-05 씨제이헬스케어 주식회사 베포타스틴 또는 이의 약학적으로 허용가능한 염과 수불용성 염기성 물질을 포함하는 약제학적 제제
CN102885810B (zh) * 2012-10-30 2015-08-05 台州职业技术学院 一种坎地沙坦酯双释胶囊及其制备方法
CA2891122C (en) 2012-11-14 2021-07-20 The Johns Hopkins University Methods and compositions for treating schizophrenia
CN103027898B (zh) * 2012-12-28 2014-11-26 深圳翰宇药业股份有限公司 一种西他列汀缓释微丸及其制备方法
KR102008490B1 (ko) * 2013-01-14 2019-08-08 주식회사 바이오파마티스 콜린 알포세레이트 또는 이의 약학적으로 허용되는 염을 포함하는 방출 조절형 약학 조성물 및 이의 제조방법
KR102241487B1 (ko) 2013-02-20 2021-04-16 주식회사 종근당 제어방출 펠릿으로 된 약제학적 조성물
EP2968220B1 (en) 2013-03-15 2021-05-05 Agenebio, Inc. Methods and compositions for improving cognitive function
EP2974720B1 (en) * 2013-03-15 2024-02-21 Korea United Pharm. Inc. Mosapride sustained-release preparation for providing pharmacological clinical effects with once-a-day administration
WO2014144663A1 (en) 2013-03-15 2014-09-18 The Johns Hopkins University Methods and compositions for improving cognitive function
US20140275038A1 (en) * 2013-03-15 2014-09-18 Inspirion Delivery Technologies, Llc Abuse deterrent compositions and methods of use
KR101497354B1 (ko) * 2013-03-29 2015-03-02 초당약품공업 주식회사 활성 성분으로 에페리손을 함유하는 서방성 제제 조성물
KR20140118410A (ko) * 2013-03-29 2014-10-08 초당약품공업 주식회사 저장 및 pH 안정성이 개선된 에페리손 의약 조성물
WO2014171542A1 (ja) * 2013-04-19 2014-10-23 武田薬品工業株式会社 放出制御製剤
WO2015012365A1 (ja) * 2013-07-25 2015-01-29 株式会社 三和化学研究所 医薬製剤
KR101597004B1 (ko) * 2013-07-25 2016-02-23 씨제이헬스케어 주식회사 서방형 메트포르민과 속방형 HMG-CoA 환원효소 억제제를 포함하는 복합제제
UA117260C2 (uk) 2013-10-29 2018-07-10 Тиллоттс Фарма АГ Лікарський препарат з відстроченим вивільненням
CN103655570B (zh) * 2013-12-11 2016-07-06 深圳翰宇药业股份有限公司 西格列汀与二甲双胍复方缓释制剂及其制备方法
KR101556568B1 (ko) * 2013-12-17 2015-10-01 주식회사 대웅제약 콜린 알포세레이트를 함유하는 필름코팅정 및 이의 제조방법
KR101631846B1 (ko) * 2014-07-08 2016-06-20 한국유나이티드제약 주식회사 콜린알포세레이트를 포함하는 고형제제 및 이의 제조방법
CN104306347A (zh) * 2014-09-19 2015-01-28 万特制药(海南)有限公司 一种卡维地洛双层缓释片及其制备方法
KR101642193B1 (ko) * 2014-10-13 2016-07-25 씨제이헬스케어 주식회사 메트포르민 서방성 제제 및 그의 제조방법
KR101628937B1 (ko) 2014-11-06 2016-06-09 환인제약 주식회사 콜린알포세레이트를 함유하는 정제 및 그 제조방법
LT3265126T (lt) 2015-03-03 2021-09-10 Saniona A/S Tesofensino ir metoprololio derinio kompozicija
KR101990951B1 (ko) 2015-04-27 2019-06-20 주식회사 네비팜 리바스티그민 함유 서방출 의약조성물
CN107810002B (zh) 2015-05-22 2021-01-05 艾吉因生物股份有限公司 左乙拉西坦的延时释放药物组合物
CN105920000B (zh) * 2016-06-27 2018-10-09 国药集团广东环球制药有限公司 硝苯地平缓释制剂及其制备方法
EP3484456A4 (en) 2016-07-17 2020-03-18 Mapi Pharma Limited RETARD PHARMACEUTICAL FORMS OF PREGABALIN
CN107661506B (zh) * 2016-07-26 2022-04-29 江苏豪森药业集团有限公司 枸橼酸莫沙必利的药物制剂及其制备方法
KR101909273B1 (ko) * 2016-12-02 2018-10-17 주식회사유한양행 메트포르민 및 HMG-CoA 환원효소 억제제를 포함하는 정제
KR101923403B1 (ko) * 2017-01-12 2018-11-29 (주)넥스팜코리아 리마프로스트 또는 리마프로스트 알파엑스를 함유한 경구용 서방성 제제 조성물
TW201834643A (zh) * 2017-02-20 2018-10-01 韓商西梯茜生命工學股份有限公司 Kr 南韓 包含鹽酸依托必利之速釋和緩釋藥物製劑
EP3592337B1 (en) * 2017-03-08 2023-07-05 Cinrx Pharma, LLC Pharmaceutical formulations of phloroglucinol and trimethylphloroglucinol
KR102189191B1 (ko) * 2017-09-12 2020-12-09 한국유나이티드제약 주식회사 1일 1회 경구투여하는 이토프라이드 염산염 함유 서방제제
KR102210422B1 (ko) * 2017-09-13 2021-02-02 한국유나이티드제약 주식회사 신규한 용출 파라미터를 이용한 이토프라이드 함유 서방제제
KR102189200B1 (ko) * 2017-09-13 2020-12-09 한국유나이티드제약 주식회사 용출 특성을 조절한 이토프라이드 염산염 함유 경구 투여 서방제제
KR102046395B1 (ko) 2017-12-12 2019-11-19 동아에스티 주식회사 베포타스틴 또는 이의 약제학적으로 허용 가능한 염을 포함하는 서방성 제제
KR102083241B1 (ko) * 2018-02-14 2020-03-02 환인제약 주식회사 라코사미드를 함유하는 약제학적 서방성 조성물
KR102018495B1 (ko) * 2018-03-13 2019-09-05 충북대학교 산학협력단 과민성 방광의 치료를 위한 서방형의 이중층 정제 및 이의 제조방법
KR102145853B1 (ko) * 2018-06-19 2020-08-19 한국유나이티드제약 주식회사 실로스타졸과 스타틴계약물을 함유하는 약학 조성물
KR20200021774A (ko) * 2018-08-21 2020-03-02 대화제약 주식회사 시타글립틴 속방층을 포함하는 제제의 제조방법, 상기 제조방법으로 제조된 제제, 시타글립틴 속방층 코팅 방법, 및 시타글립틴 속방층 코팅용 조성물
KR102244108B1 (ko) * 2018-12-21 2021-04-23 (주)휴온스 티카그렐러 또는 이의 염을 함유하는 서방형 약제학적 조성물
CN113784705A (zh) * 2019-04-12 2021-12-10 财团法人医药工业技术发展中心 治疗精神疾病的控释药物组合物和方法
KR102236650B1 (ko) * 2019-04-16 2021-04-07 한국유나이티드제약 주식회사 아세클로페낙을 포함하는 약학조성물 및 이의 제조방법
US20230040902A1 (en) * 2019-12-19 2023-02-09 Celltrion Inc. Pharmaceutical Formulation Comprising Cibenzoline or Salt Thereof
AR126544A1 (es) 2021-07-23 2023-10-18 Lesvi Laboratorios Sl Composición farmacéutica multiparticulada

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20040079980A (ko) * 2002-02-01 2004-09-16 데포메드 인코퍼레이티드 속방성 및 서방성 약물 모두를 송달하는 경구 투약 형태의제조방법
KR20070078625A (ko) * 2006-01-27 2007-08-01 씨제이 주식회사 멀티플 유닛 타입 서방성 경구 제제 및 그 제조방법
KR20070085155A (ko) * 2006-02-22 2007-08-27 코와 가부시키가이샤 이부프로펜 함유 코팅 과립
KR20080032616A (ko) * 2006-10-10 2008-04-15 한올제약주식회사 시간차 투약 원리를 이용한 심혈관계 질환 치료용 복합제제

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3115441A (en) * 1962-06-06 1963-12-24 Victor M Hermelin Timed release pharmaceutical preparations and method of making the same
US4820522A (en) 1987-07-27 1989-04-11 Mcneilab, Inc. Oral sustained release acetaminophen formulation and process
EP1121103B1 (en) * 1998-05-18 2006-12-20 Takeda Pharmaceutical Company Limited Orally disintegrable tablets comprising a benzimidazole
US6126967A (en) * 1998-09-03 2000-10-03 Ascent Pediatrics Extended release acetaminophen particles
US6248363B1 (en) * 1999-11-23 2001-06-19 Lipocine, Inc. Solid carriers for improved delivery of active ingredients in pharmaceutical compositions
EP1064938A1 (en) 1999-06-28 2001-01-03 Sanofi-Synthelabo Pharmaceutical dosage forms for controlled release producing at least a timed pulse
US6627223B2 (en) * 2000-02-11 2003-09-30 Eurand Pharmaceuticals Ltd. Timed pulsatile drug delivery systems
WO2002087549A1 (fr) * 2001-04-25 2002-11-07 Taisho Pharmaceutical Co., Ltd. Comprimes a liberation prolongee du type a unites multiples
US6669955B2 (en) * 2001-08-28 2003-12-30 Longwood Pharmaceutical Research, Inc. Combination dosage form containing individual dosage units of a cholesterol-lowering agent, an inhibitor of the renin-angiotensin system, and aspirin
US7387793B2 (en) * 2003-11-14 2008-06-17 Eurand, Inc. Modified release dosage forms of skeletal muscle relaxants
CA2570796A1 (en) * 2004-06-15 2006-01-05 Teva Pharmaceutical Industries Ltd. Stable pharmaceutical formulations of benzimidazole compounds
WO2006036007A2 (en) 2004-09-30 2006-04-06 Takeda Pharmaceutical Company Limited Modified-release preparation
JP2006124385A (ja) * 2004-09-30 2006-05-18 Takeda Chem Ind Ltd 放出制御製剤
CN1785167A (zh) * 2005-10-08 2006-06-14 王鸣 一种非麻醉性镇痛剂的复方缓释制剂的制备方法
US20090022798A1 (en) * 2007-07-20 2009-01-22 Abbott Gmbh & Co. Kg Formulations of nonopioid and confined opioid analgesics
EP2079452A4 (en) * 2006-10-30 2010-01-06 Hanall Pharmaceutical Co Ltd CONTROLLED RELEASE PHARMACEUTICAL COMPOSITION CONTAINING THIAZIDS AND BLOCKERS OF ANGIOTENSIN II RECEPTORS
AU2007319141B2 (en) * 2006-11-17 2013-01-10 Supernus Pharmaceuticals Inc. Sustained-release formulations of topiramate
WO2008081891A1 (ja) * 2006-12-28 2008-07-10 Takeda Pharmaceutical Company Limited 口腔内崩壊性固形製剤
CN101015519B (zh) * 2007-02-27 2012-03-21 重庆医药工业研究院有限责任公司 一种氯雷他定口服复方药物组合物

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20040079980A (ko) * 2002-02-01 2004-09-16 데포메드 인코퍼레이티드 속방성 및 서방성 약물 모두를 송달하는 경구 투약 형태의제조방법
KR20070078625A (ko) * 2006-01-27 2007-08-01 씨제이 주식회사 멀티플 유닛 타입 서방성 경구 제제 및 그 제조방법
KR20070085155A (ko) * 2006-02-22 2007-08-27 코와 가부시키가이샤 이부프로펜 함유 코팅 과립
KR20080032616A (ko) * 2006-10-10 2008-04-15 한올제약주식회사 시간차 투약 원리를 이용한 심혈관계 질환 치료용 복합제제

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of EP2486918A4 *

Also Published As

Publication number Publication date
WO2011049309A2 (ko) 2011-04-28
US20110217374A1 (en) 2011-09-08
JP2013507356A (ja) 2013-03-04
CN102548544B (zh) 2015-01-21
EP2486918A4 (en) 2014-02-26
EP2486918A2 (en) 2012-08-15
KR101573889B1 (ko) 2015-12-04
US9180101B2 (en) 2015-11-10
KR20120083276A (ko) 2012-07-25
JP5827952B2 (ja) 2015-12-02
CN102548544A (zh) 2012-07-04

Similar Documents

Publication Publication Date Title
WO2011049309A3 (ko) 속효성과 지속성을 동시에 갖는 약제학적 조성물
WO2009113703A3 (en) Orally-disintegrating solid preparation
EP3607938A3 (en) Pharmaceutical composition
NZ600123A (en) Compressible-coated pharmaceutical compositions and tablets and methods of manufacture
WO2009009627A3 (en) Endoprosthesis coating
WO2009117130A3 (en) Extended release forumulation containing a wax
WO2010125323A8 (en) Biocidal composition
WO2012034079A3 (en) Macrolide dosage forms
WO2011039768A3 (en) Pharmaceutical compositions for reducing alcohol-induced dose dumping
MX2011009669A (es) Composición farmacéutica de liberación controlada con resistencia a la influencia de etanol mediante un revestimiento compuesto de una mezcla polimérica y excipientes.
WO2008132229A3 (en) Highly concentrated insulin solutions and compositions
WO2011051971A3 (en) Solid dispersion of rifaximin
WO2010024615A3 (ko) 용매교류증발법에 의한 서방출성 미립구의 제조방법
WO2012085043A3 (en) Rapidly disintegrating, solid coated dosage form
WO2010049454A3 (en) Antimicrobial composition from copepods
WO2011067667A3 (en) Fexofenadine microcapsules and compositions containing them
WO2012001705A3 (en) Pharmaceutical compositions of (r)-lansoprazole
WO2013012666A3 (en) Compounds, methods of making, and methods of use
WO2011077239A3 (en) Slow release pharmaceutical compositions of iloperidone
WO2011037976A3 (en) Pramipexole pharmaceutical formulations
WO2008129501A3 (en) Pharmaceutical compositions of duloxetine
WO2011107944A3 (en) Modified release dosage form
WO2012075015A3 (en) Oral metronidazole pharmaceutical compositions
EP2522348A4 (en) COATED PREPARATION CONTAINING ATROVASTATIN
WO2007113207A3 (en) Coated formulations

Legal Events

Date Code Title Description
WWE Wipo information: entry into national phase

Ref document number: 201080045422.0

Country of ref document: CN

121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 10825134

Country of ref document: EP

Kind code of ref document: A1

ENP Entry into the national phase

Ref document number: 20127003314

Country of ref document: KR

Kind code of ref document: A

WWE Wipo information: entry into national phase

Ref document number: 2010825134

Country of ref document: EP

WWE Wipo information: entry into national phase

Ref document number: 2012533089

Country of ref document: JP

NENP Non-entry into the national phase

Ref country code: DE