MX2010001170A - Derivados de imidazolona, metodo de preparacion de los mismos y uso biologico de los mismos. - Google Patents

Derivados de imidazolona, metodo de preparacion de los mismos y uso biologico de los mismos.

Info

Publication number
MX2010001170A
MX2010001170A MX2010001170A MX2010001170A MX2010001170A MX 2010001170 A MX2010001170 A MX 2010001170A MX 2010001170 A MX2010001170 A MX 2010001170A MX 2010001170 A MX2010001170 A MX 2010001170A MX 2010001170 A MX2010001170 A MX 2010001170A
Authority
MX
Mexico
Prior art keywords
preparation
aryl
same
alkyl
imidazolone derivatives
Prior art date
Application number
MX2010001170A
Other languages
English (en)
Spanish (es)
Inventor
Francois Carreaux
Jean-Pierre Bazureau
Steven Renault
Laurent Meijer
Olivier Lozach
Original Assignee
Univ Rennes
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Rennes filed Critical Univ Rennes
Publication of MX2010001170A publication Critical patent/MX2010001170A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/96—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
MX2010001170A 2007-08-01 2008-08-01 Derivados de imidazolona, metodo de preparacion de los mismos y uso biologico de los mismos. MX2010001170A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0705632A FR2919608B1 (fr) 2007-08-01 2007-08-01 Derives d'imidazolones,procede de preparation et applications biologiques
PCT/FR2008/001152 WO2009050352A2 (fr) 2007-08-01 2008-08-01 Derives d'imidazolones, procede de preparation et applications biologiques

Publications (1)

Publication Number Publication Date
MX2010001170A true MX2010001170A (es) 2010-06-25

Family

ID=39323606

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2010001170A MX2010001170A (es) 2007-08-01 2008-08-01 Derivados de imidazolona, metodo de preparacion de los mismos y uso biologico de los mismos.

Country Status (12)

Country Link
US (1) US8563588B2 (enExample)
EP (1) EP2185547B1 (enExample)
JP (1) JP5926885B2 (enExample)
KR (1) KR20100051698A (enExample)
CN (1) CN101784542B (enExample)
BR (1) BRPI0814457A2 (enExample)
CA (1) CA2694377A1 (enExample)
ES (1) ES2644087T3 (enExample)
FR (1) FR2919608B1 (enExample)
MX (1) MX2010001170A (enExample)
RU (1) RU2491283C2 (enExample)
WO (1) WO2009050352A2 (enExample)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
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US10316000B2 (en) 2009-02-18 2019-06-11 Cornell University Coupled recognition/detection system for in vivo and in vitro use
EP2281824A1 (en) 2009-08-07 2011-02-09 Noscira, S.A. Furan-imidazolone derivatives, for the treatment of cognitive, neurodegenerative or neuronal diseases or disorders
WO2013016694A2 (en) 2011-07-27 2013-01-31 Cornell University Methods for rna detection and quantification
JP5910976B2 (ja) * 2012-07-30 2016-04-27 国立大学法人京都大学 精神神経疾患又は悪性腫瘍に関する化合物及び医薬組成物
FR3002044A1 (fr) * 2013-02-08 2014-08-15 Centre Nat Rech Scient Marqueur dyrk1a pour la maladie d'alzheimer
CN106061258A (zh) * 2013-08-29 2016-10-26 弗吉尼亚联邦大学 制造2‑卤代烟腈的方法
US9664676B2 (en) 2013-09-06 2017-05-30 Cornell University RNA sequences that induce fluorescence of small molecule fluorophores
CN104370891B (zh) * 2014-10-17 2016-09-07 中国农业大学 一种5-(丁烯内酯-3-亚乙基)-2-氨基咪唑啉酮类化合物、制备方法及其应用
RU2730550C1 (ru) * 2019-05-15 2020-08-24 Федеральное государственное бюджетное образовательное учреждение высшего образования "Московский государственный университет имени М.В. Ломоносова" (МГУ) Производное 2-селеноксо-тетрагидро-4н-имидазол-4-она, способ его получения и применения
WO2021114314A1 (en) * 2019-12-14 2021-06-17 Tongji University Novel heterocyclic derivatives with cardiomyocyte proliferation activity for treatment of heart diseases
JP7559082B2 (ja) * 2019-12-14 2024-10-01 シャンハイ イースト ホスピタル（イースト ホスピタル，トンジ ユニバーシティ スクール オブ メディシン） 心臓病の治療のための心筋細胞増殖活性を有する複素環式誘導体の使用
KR102491260B1 (ko) * 2019-12-26 2023-01-27 연세대학교 산학협력단 피롤리딘 유도체 및 이를 포함하는 베타-아밀로이드 또는 타우 단백질 관련 질병의 예방 또는 치료용 약학 조성물
WO2021219828A1 (en) * 2020-04-30 2021-11-04 Perha Pharmaceuticals New imidazolone derivatives as inhibitors of protein kinases in particular dyrk1a, clk1 and/or clk4
EP3904354A1 (en) 2020-04-30 2021-11-03 Perha Pharmaceuticals New imidazolone derivatives as inhibitors of protein kinases in particular dyrk1a, clk1 and/or clk4
EP4173673A1 (en) 2021-10-26 2023-05-03 Perha Pharmaceuticals Imidazolone derivatives as inhibitors of protein kinases in particular dyrk1a, clk1 and/or clk4
EP4173675A1 (en) 2021-10-26 2023-05-03 Perha Pharmaceuticals Imidazolone derivatives as inhibitors of protein kinases in particular dyrk1a, clk1 and/or clk4
EP4173674A1 (en) 2021-10-26 2023-05-03 Perha Pharmaceuticals Imidazolone derivatives as inhibitors of protein kinases in particular dyrk1a, clk1 and/or clk4
WO2025069008A1 (en) 2023-09-28 2025-04-03 Graviton Bioscience Bv Therapy for treating type 1 diabetes using rock2 and dyrk1 inhibitors

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DE1038050B (de) * 1955-11-17 1958-09-04 Farmaceutici Italia S A Soc Verfahren zur Herstellung von 5-(3', 4'-Dioxybenzyliden)-Derivaten heterocyclischer Verbindungen
US4431656A (en) * 1981-02-05 1984-02-14 Kanegafuchi Chemical Industry Company Limited 3,5-di-Tert-butylstyrene derivatives, salts thereof, and pharmaceutical compositions containing the same as an active ingredient
GR79384B (enExample) * 1982-08-20 1984-10-22 Hoechst Uk Ltd
IE940525L (en) * 1988-05-25 1989-11-25 Warner Lambert Co Known and selected novel arylmethylenyl derivatives of¹thiazolidinones, imidazolidinones and oxazolidinones useful¹as antiallergy agents and antiinflammatory agents
EP0422900B1 (en) * 1989-10-09 1994-03-16 Kabushiki Kaisha Toshiba Organic nonlinear optical material and nonlinear optical element
US5143928A (en) * 1990-03-27 1992-09-01 Warner-Lambert Company 3,5-di-tertiarybutyl-4-hydroxyphenylmethylene derivatives of 2-substituted thiazolidinones, oxazolidinones, and imidazolidinones as antiinflammatory agents
PL166269B1 (pl) * 1990-04-27 1995-04-28 Orion Yh Tyma Oy Sposób wytwarzania nowych farmakologicznie aktywnych pochodnych katecholul PL PL PL PL PL
JP3015702B2 (ja) * 1995-02-21 2000-03-06 株式会社アラクス イミダゾール誘導体及びそれらの薬剤として許容される酸付加塩及びその製造法並びにそれらを有効成分とする抗潰瘍剤
US6218437B1 (en) * 1996-09-30 2001-04-17 The Regents Of The University Of California Treatment and prevention of hepatic disorders
PL187019B1 (pl) * 1997-02-19 2004-04-30 Univ Jagiellonski Collegium Me Nowe związki, pochodne 5-arylideno-4-okso-2-imidazolidynoglicyny
EG21566A (en) * 1999-09-21 2001-12-31 Hosny Hamed Hoharam Synthesis of 5-(4-dimethylaminobenzli-dene)-2-phenylhydrozino (1,3-h) imidazole-4-one (iii)
WO2004052373A1 (en) * 2002-12-06 2004-06-24 Warner-Lambert Company Llc Benzoxazin-3-ones and derivatives thereof as inhibitors of pi3k
FR2855755B1 (fr) * 2003-06-05 2007-09-07 Oreal Utilisation d'au moins un filtre de la lumiere bleue pour preserve le capital de carotenoides endogenes de la peau; nouveaux filtres de la lumiere bleue; compositions cosmetiques
ES2328146T3 (es) * 2003-07-28 2009-11-10 Merck Serono Sa 2-imino-4-(tio)oxo-5-policiclovinilazolinas para su uso como inhibidores de p13 quinasas.
RU2405781C2 (ru) * 2004-10-14 2010-12-10 Ф.Хоффманн-Ля Рош Аг 1, 5-нафтиридиназолидиноны, обладающие cdk1 антипролиферативной активностью
WO2006105237A2 (en) * 2005-03-29 2006-10-05 The University Of Maryland, Baltimore Inhibitors for extracellular signal-regulated kinase docking domains and uses therefor
US7304074B2 (en) * 2005-04-05 2007-12-04 Hoffmann-La Roche Inc. Substituted 1,5-naphthyridine azolinones
JP2007063444A (ja) * 2005-08-31 2007-03-15 Tdk Corp 錯化合物及びこれを用いた光記録媒体
US7371862B2 (en) * 2005-11-11 2008-05-13 Pfizer Italia S.R.L. Azaindolylidene derivatives as kinase inhibitors, process for their preparation and pharmaceutical compositions comprising them
US20080280920A1 (en) * 2005-12-07 2008-11-13 Trifonov Latchezar S Plasminogen Activator Inhibitor-1 Inhibitors

Also Published As

Publication number Publication date
EP2185547A2 (fr) 2010-05-19
JP5926885B2 (ja) 2016-05-25
ES2644087T3 (es) 2017-11-27
WO2009050352A3 (fr) 2009-07-23
RU2491283C2 (ru) 2013-08-27
WO2009050352A2 (fr) 2009-04-23
RU2010107262A (ru) 2011-09-10
FR2919608B1 (fr) 2012-10-05
BRPI0814457A2 (pt) 2015-01-06
CN101784542B (zh) 2014-04-02
JP2010535180A (ja) 2010-11-18
EP2185547B1 (fr) 2017-07-19
CA2694377A1 (fr) 2009-04-23
US20100216855A1 (en) 2010-08-26
KR20100051698A (ko) 2010-05-17
US8563588B2 (en) 2013-10-22
FR2919608A1 (fr) 2009-02-06
CN101784542A (zh) 2010-07-21

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