BRPI0814457A2 - Derivados de imidazolona, composições farmacêuticas, utilização de derivados de imidazolona, e, processo de síntese de derivados de imidazolona - Google Patents
Derivados de imidazolona, composições farmacêuticas, utilização de derivados de imidazolona, e, processo de síntese de derivados de imidazolonaInfo
- Publication number
- BRPI0814457A2 BRPI0814457A2 BRPI0814457-5A2A BRPI0814457A BRPI0814457A2 BR PI0814457 A2 BRPI0814457 A2 BR PI0814457A2 BR PI0814457 A BRPI0814457 A BR PI0814457A BR PI0814457 A2 BRPI0814457 A2 BR PI0814457A2
- Authority
- BR
- Brazil
- Prior art keywords
- imidazolone derivatives
- immedazolone
- pharmaceutical compositions
- synthesis process
- derivative synthesis
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/96—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR0705632A FR2919608B1 (fr) | 2007-08-01 | 2007-08-01 | Derives d'imidazolones,procede de preparation et applications biologiques |
PCT/FR2008/001152 WO2009050352A2 (fr) | 2007-08-01 | 2008-08-01 | Derives d'imidazolones, procede de preparation et applications biologiques |
Publications (1)
Publication Number | Publication Date |
---|---|
BRPI0814457A2 true BRPI0814457A2 (pt) | 2015-01-06 |
Family
ID=39323606
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI0814457-5A2A BRPI0814457A2 (pt) | 2007-08-01 | 2008-08-01 | Derivados de imidazolona, composições farmacêuticas, utilização de derivados de imidazolona, e, processo de síntese de derivados de imidazolona |
Country Status (12)
Country | Link |
---|---|
US (1) | US8563588B2 (pt) |
EP (1) | EP2185547B1 (pt) |
JP (1) | JP5926885B2 (pt) |
KR (1) | KR20100051698A (pt) |
CN (1) | CN101784542B (pt) |
BR (1) | BRPI0814457A2 (pt) |
CA (1) | CA2694377A1 (pt) |
ES (1) | ES2644087T3 (pt) |
FR (1) | FR2919608B1 (pt) |
MX (1) | MX2010001170A (pt) |
RU (1) | RU2491283C2 (pt) |
WO (1) | WO2009050352A2 (pt) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102405212B (zh) | 2009-02-18 | 2016-01-27 | 康奈尔大学 | 在体内外使用的偶联识别/检测系统 |
EP2281824A1 (en) | 2009-08-07 | 2011-02-09 | Noscira, S.A. | Furan-imidazolone derivatives, for the treatment of cognitive, neurodegenerative or neuronal diseases or disorders |
WO2013016694A2 (en) | 2011-07-27 | 2013-01-31 | Cornell University | Methods for rna detection and quantification |
ES2820553T3 (es) * | 2012-07-30 | 2021-04-21 | Univ Kyoto | Compuesto y composición farmacéutica para trastorno neuropsicológico o tumor maligno |
FR3002044A1 (fr) * | 2013-02-08 | 2014-08-15 | Centre Nat Rech Scient | Marqueur dyrk1a pour la maladie d'alzheimer |
CN106061258A (zh) * | 2013-08-29 | 2016-10-26 | 弗吉尼亚联邦大学 | 制造2‑卤代烟腈的方法 |
US9664676B2 (en) | 2013-09-06 | 2017-05-30 | Cornell University | RNA sequences that induce fluorescence of small molecule fluorophores |
CN104370891B (zh) * | 2014-10-17 | 2016-09-07 | 中国农业大学 | 一种5-(丁烯内酯-3-亚乙基)-2-氨基咪唑啉酮类化合物、制备方法及其应用 |
RU2730550C1 (ru) * | 2019-05-15 | 2020-08-24 | Федеральное государственное бюджетное образовательное учреждение высшего образования "Московский государственный университет имени М.В. Ломоносова" (МГУ) | Производное 2-селеноксо-тетрагидро-4н-имидазол-4-она, способ его получения и применения |
WO2021114314A1 (en) * | 2019-12-14 | 2021-06-17 | Tongji University | Novel heterocyclic derivatives with cardiomyocyte proliferation activity for treatment of heart diseases |
WO2021114315A1 (en) * | 2019-12-14 | 2021-06-17 | Shanghai East Hospital | Use of heterocyclic derivatives with cardiomyocyte proliferation activity for treatment of heart diseases |
EP3904354A1 (en) | 2020-04-30 | 2021-11-03 | Perha Pharmaceuticals | New imidazolone derivatives as inhibitors of protein kinases in particular dyrk1a, clk1 and/or clk4 |
AU2021266141A1 (en) | 2020-04-30 | 2022-12-01 | Perha Pharmaceuticals | New imidazolone derivatives as inhibitors of protein kinases in particular DYRK1A, CLK1 and/or CLK4 |
EP4173674A1 (en) | 2021-10-26 | 2023-05-03 | Perha Pharmaceuticals | Imidazolone derivatives as inhibitors of protein kinases in particular dyrk1a, clk1 and/or clk4 |
EP4173675A1 (en) | 2021-10-26 | 2023-05-03 | Perha Pharmaceuticals | Imidazolone derivatives as inhibitors of protein kinases in particular dyrk1a, clk1 and/or clk4 |
EP4173673A1 (en) | 2021-10-26 | 2023-05-03 | Perha Pharmaceuticals | Imidazolone derivatives as inhibitors of protein kinases in particular dyrk1a, clk1 and/or clk4 |
Family Cites Families (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE1038050B (de) * | 1955-11-17 | 1958-09-04 | Farmaceutici Italia S A Soc | Verfahren zur Herstellung von 5-(3', 4'-Dioxybenzyliden)-Derivaten heterocyclischer Verbindungen |
DD95843A5 (pt) * | 1971-01-21 | 1973-02-20 | ||
US4431656A (en) * | 1981-02-05 | 1984-02-14 | Kanegafuchi Chemical Industry Company Limited | 3,5-di-Tert-butylstyrene derivatives, salts thereof, and pharmaceutical compositions containing the same as an active ingredient |
GR79384B (pt) * | 1982-08-20 | 1984-10-22 | Hoechst Uk Ltd | |
IE62214B1 (en) * | 1988-05-25 | 1995-01-11 | Warner Lambert Co | Arylmethylenyl derivatives of thiazolidinones, imidazolidinones and oxazolidinones useful as antiallergy agents and antiinflammatory agents |
EP0422900B1 (en) * | 1989-10-09 | 1994-03-16 | Kabushiki Kaisha Toshiba | Organic nonlinear optical material and nonlinear optical element |
US5143928A (en) * | 1990-03-27 | 1992-09-01 | Warner-Lambert Company | 3,5-di-tertiarybutyl-4-hydroxyphenylmethylene derivatives of 2-substituted thiazolidinones, oxazolidinones, and imidazolidinones as antiinflammatory agents |
PL166269B1 (pl) * | 1990-04-27 | 1995-04-28 | Orion Yh Tyma Oy | Sposób wytwarzania nowych farmakologicznie aktywnych pochodnych katecholul PL PL PL PL PL |
JP3015702B2 (ja) * | 1995-02-21 | 2000-03-06 | 株式会社アラクス | イミダゾール誘導体及びそれらの薬剤として許容される酸付加塩及びその製造法並びにそれらを有効成分とする抗潰瘍剤 |
US6218437B1 (en) * | 1996-09-30 | 2001-04-17 | The Regents Of The University Of California | Treatment and prevention of hepatic disorders |
PL187019B1 (pl) * | 1997-02-19 | 2004-04-30 | Univ Jagiellonski Collegium Me | Nowe związki, pochodne 5-arylideno-4-okso-2-imidazolidynoglicyny |
EG21566A (en) * | 1999-09-21 | 2001-12-31 | Hosny Hamed Hoharam | Synthesis of 5-(4-dimethylaminobenzli-dene)-2-phenylhydrozino (1,3-h) imidazole-4-one (iii) |
AU2003280188A1 (en) * | 2002-12-06 | 2004-06-30 | Warner-Lambert Company Llc | Benzoxazin-3-ones and derivatives thereof as inhibitors of pi3k |
FR2855755B1 (fr) * | 2003-06-05 | 2007-09-07 | Oreal | Utilisation d'au moins un filtre de la lumiere bleue pour preserve le capital de carotenoides endogenes de la peau; nouveaux filtres de la lumiere bleue; compositions cosmetiques |
JP4908210B2 (ja) * | 2003-07-28 | 2012-04-04 | メルク セローノ ソシエテ アノニム | Pi3キナーゼ阻害剤として使用するための2−イミノ−4−(チオ)オキソ−5−ポリシクロビニルアゾリン類 |
CN101039944B (zh) * | 2004-10-14 | 2010-05-05 | 霍夫曼-拉罗奇有限公司 | 具有cdk1抗增殖活性的1,5-二氮杂萘唑烷酮类 |
US20090299063A1 (en) * | 2005-03-29 | 2009-12-03 | Paul Shapiro | Inhibitors for Extracellular Signal-Regulated Kinase Docking Domains and Uses Therefor |
US7304074B2 (en) * | 2005-04-05 | 2007-12-04 | Hoffmann-La Roche Inc. | Substituted 1,5-naphthyridine azolinones |
JP2007063444A (ja) * | 2005-08-31 | 2007-03-15 | Tdk Corp | 錯化合物及びこれを用いた光記録媒体 |
US7371862B2 (en) * | 2005-11-11 | 2008-05-13 | Pfizer Italia S.R.L. | Azaindolylidene derivatives as kinase inhibitors, process for their preparation and pharmaceutical compositions comprising them |
EP1960395A4 (en) * | 2005-12-07 | 2009-12-02 | American Diagnostica Inc | INHIBITORS OF PLASMINOGENACTIVATORINHIBITOR-1 |
-
2007
- 2007-08-01 FR FR0705632A patent/FR2919608B1/fr active Active
-
2008
- 2008-08-01 BR BRPI0814457-5A2A patent/BRPI0814457A2/pt not_active IP Right Cessation
- 2008-08-01 KR KR1020107004568A patent/KR20100051698A/ko not_active Application Discontinuation
- 2008-08-01 US US12/452,940 patent/US8563588B2/en active Active
- 2008-08-01 CN CN200880103961.8A patent/CN101784542B/zh active Active
- 2008-08-01 JP JP2010518711A patent/JP5926885B2/ja active Active
- 2008-08-01 ES ES08838929.1T patent/ES2644087T3/es active Active
- 2008-08-01 CA CA2694377A patent/CA2694377A1/fr not_active Abandoned
- 2008-08-01 EP EP08838929.1A patent/EP2185547B1/fr active Active
- 2008-08-01 RU RU2010107262/04A patent/RU2491283C2/ru active
- 2008-08-01 WO PCT/FR2008/001152 patent/WO2009050352A2/fr active Application Filing
- 2008-08-01 MX MX2010001170A patent/MX2010001170A/es active IP Right Grant
Also Published As
Publication number | Publication date |
---|---|
CN101784542A (zh) | 2010-07-21 |
KR20100051698A (ko) | 2010-05-17 |
WO2009050352A2 (fr) | 2009-04-23 |
US8563588B2 (en) | 2013-10-22 |
MX2010001170A (es) | 2010-06-25 |
FR2919608A1 (fr) | 2009-02-06 |
JP5926885B2 (ja) | 2016-05-25 |
FR2919608B1 (fr) | 2012-10-05 |
ES2644087T3 (es) | 2017-11-27 |
US20100216855A1 (en) | 2010-08-26 |
RU2491283C2 (ru) | 2013-08-27 |
JP2010535180A (ja) | 2010-11-18 |
EP2185547B1 (fr) | 2017-07-19 |
RU2010107262A (ru) | 2011-09-10 |
EP2185547A2 (fr) | 2010-05-19 |
WO2009050352A3 (fr) | 2009-07-23 |
CN101784542B (zh) | 2014-04-02 |
CA2694377A1 (fr) | 2009-04-23 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B08F | Application fees: application dismissed [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 8A ANUIDADE. |
|
B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2385 DE 20-09-2016 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013. |