MX2009011139A - Ligandos de receptor vainilloide novedosos y el uso de los mismos para la produccion de farmacos. - Google Patents
Ligandos de receptor vainilloide novedosos y el uso de los mismos para la produccion de farmacos.Info
- Publication number
- MX2009011139A MX2009011139A MX2009011139A MX2009011139A MX2009011139A MX 2009011139 A MX2009011139 A MX 2009011139A MX 2009011139 A MX2009011139 A MX 2009011139A MX 2009011139 A MX2009011139 A MX 2009011139A MX 2009011139 A MX2009011139 A MX 2009011139A
- Authority
- MX
- Mexico
- Prior art keywords
- production
- pharmaceuticals
- receptor ligands
- vanilloid receptor
- novel vanilloid
- Prior art date
Links
- 239000003814 drug Substances 0.000 title abstract 5
- 102000011040 TRPV Cation Channels Human genes 0.000 title abstract 2
- 108010062740 TRPV Cation Channels Proteins 0.000 title abstract 2
- 239000003446 ligand Substances 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 2
- 229940079593 drug Drugs 0.000 abstract 2
- 208000019901 Anxiety disease Diseases 0.000 abstract 1
- 206010011224 Cough Diseases 0.000 abstract 1
- 206010012735 Diarrhoea Diseases 0.000 abstract 1
- 208000030814 Eating disease Diseases 0.000 abstract 1
- 208000019454 Feeding and Eating disease Diseases 0.000 abstract 1
- 206010061218 Inflammation Diseases 0.000 abstract 1
- 208000019695 Migraine disease Diseases 0.000 abstract 1
- 208000003251 Pruritus Diseases 0.000 abstract 1
- 206010046543 Urinary incontinence Diseases 0.000 abstract 1
- 210000000748 cardiovascular system Anatomy 0.000 abstract 1
- 208000010877 cognitive disease Diseases 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000035475 disorder Diseases 0.000 abstract 1
- 235000014632 disordered eating Nutrition 0.000 abstract 1
- 206010015037 epilepsy Diseases 0.000 abstract 1
- 230000004054 inflammatory process Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
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- C07D213/62—Oxygen or sulfur atoms
- C07D213/63—One oxygen atom
- C07D213/64—One oxygen atom attached in position 2 or 6
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- C07D213/62—Oxygen or sulfur atoms
- C07D213/70—Sulfur atoms
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Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE102007018151A DE102007018151A1 (de) | 2007-04-16 | 2007-04-16 | Neue Vanilloid-Rezeptor Liganden und ihre Verwendung zur Herstellung von Arzneimitteln |
| PCT/EP2008/002994 WO2008125337A2 (de) | 2007-04-16 | 2008-04-15 | Neue vanilloid-rezeptor liganden und ihre verwendung zur herstellung von arzneimitteln |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2009011139A true MX2009011139A (es) | 2009-10-30 |
Family
ID=39540731
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2009011139A MX2009011139A (es) | 2007-04-16 | 2008-04-15 | Ligandos de receptor vainilloide novedosos y el uso de los mismos para la produccion de farmacos. |
Country Status (16)
| Country | Link |
|---|---|
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| EP (1) | EP2146962A2 (enExample) |
| JP (1) | JP5557734B2 (enExample) |
| KR (1) | KR101497357B1 (enExample) |
| CN (1) | CN101687799B (enExample) |
| BR (1) | BRPI0810031A2 (enExample) |
| CA (1) | CA2683910A1 (enExample) |
| CO (1) | CO6220938A2 (enExample) |
| DE (1) | DE102007018151A1 (enExample) |
| EC (1) | ECSP099693A (enExample) |
| IL (1) | IL201506A0 (enExample) |
| MX (1) | MX2009011139A (enExample) |
| NZ (2) | NZ580381A (enExample) |
| RU (1) | RU2487120C2 (enExample) |
| WO (1) | WO2008125337A2 (enExample) |
| ZA (1) | ZA200907096B (enExample) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2010506914A (ja) * | 2006-10-18 | 2010-03-04 | メルク エンド カムパニー インコーポレーテッド | アンドロゲン受容体モジュレーターとしての2−ヒドロキシ−2−フェニル/チオフェニルプロピオンアミド |
| WO2008110351A2 (en) * | 2007-03-15 | 2008-09-18 | Dompe' Pha.R.Ma S.P.A. | Use of (r) and (s)-2-aryl-propionic acid derivatives as antiseptic agents |
| DE102007018151A1 (de) * | 2007-04-16 | 2008-10-23 | Günenthal GmbH | Neue Vanilloid-Rezeptor Liganden und ihre Verwendung zur Herstellung von Arzneimitteln |
| WO2012158844A1 (en) | 2011-05-17 | 2012-11-22 | Shionogi & Co., Ltd. | Heterocyclic compounds |
| JP2013014534A (ja) * | 2011-07-04 | 2013-01-24 | Daicel Corp | ベンゾイルギ酸化合物、及びその製造方法 |
| BR112014001714A2 (pt) | 2011-07-26 | 2017-02-14 | Gruenenthal Gmbh | derivados de carboxamida e ureia aromáticos bicíclicos substituídos como ligantes de receptor vaniloide |
| WO2013013817A1 (en) | 2011-07-26 | 2013-01-31 | Grünenthal GmbH | Substituted heterocyclic aza derivatives |
| AR088702A1 (es) * | 2011-11-09 | 2014-06-25 | Gruenenthal Gmbh | Derivados de carboxamida y urea, basados en pirazolilo sustituido, que presentan una porcion fenilo sustituida con un grupo que contiene o como ligando de receptor vainilloide |
| CA2854935A1 (en) * | 2011-11-09 | 2013-05-16 | Grunenthal Gmbh | Substituted pyrazolyl-based carboxamide and urea derivatives bearing a phenyl moiety substituted with an n-containing group as vanilloid receptor ligands |
| US20220363667A1 (en) | 2018-07-17 | 2022-11-17 | Nippon Chemiphar Co., Ltd. | T-type calcium channel blocker |
| AU2020250468A1 (en) | 2019-03-29 | 2021-11-04 | Kinki University | Use of T-type calcium channel blocker for treating pruritus |
| RU2755206C1 (ru) | 2020-05-20 | 2021-09-14 | Федеральное государственное бюджетное учреждение науки Тихоокеанский институт биоорганической химии им. Г.Б. Елякова Дальневосточного отделения Российской академии наук (ТИБОХ ДВО РАН) | Средство пролонгированного анальгетического действия и лекарственный препарат на его основе |
| CN115417809A (zh) * | 2022-09-05 | 2022-12-02 | 天津药明康德新药开发有限公司 | 一种4,4-二吡咯-2,2-联吡啶的制备方法 |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2001011965A1 (en) | 1999-08-18 | 2001-02-22 | Aventis Cropscience Gmbh | Fungicides |
| GB9919588D0 (en) * | 1999-08-18 | 1999-10-20 | Hoechst Schering Agrevo Gmbh | Fungicidal compounds |
| KR100453078B1 (ko) | 2000-08-21 | 2004-10-15 | 주식회사 태평양 | 신규 티오우레아 화합물 및 이를 함유하는 약제학적 조성물 |
| TWI239942B (en) * | 2001-06-11 | 2005-09-21 | Dainippon Pharmaceutical Co | N-arylphenylacetamide derivative and pharmaceutical composition containing the same |
| US20030083345A1 (en) * | 2001-07-10 | 2003-05-01 | Torsten Hoffmann | Method of treatment and/or prevention of brain, spinal or nerve injury |
| FR2836917B1 (fr) | 2002-03-11 | 2006-02-24 | Lipha | Derives nitroso de la diphenylamine, compositions pharmaceutiques les contenant en tant que medicaments utilisables dans le traitement des pathologies caracterisees par une situation de stress oxydatif |
| EP1487786A2 (de) | 2002-03-14 | 2004-12-22 | Basf Aktiengesellschaft | Z-substituierte acrylamide, verfahren zu deren herstellung, sowie sie enthaltende mittel |
| US7135493B2 (en) | 2003-01-13 | 2006-11-14 | Astellas Pharma Inc. | HDAC inhibitor |
| US6933311B2 (en) | 2003-02-11 | 2005-08-23 | Abbott Laboratories | Fused azabicyclic compounds that inhibit vanilloid receptor subtype 1 (VR1) receptor |
| SE0301446D0 (sv) * | 2003-05-16 | 2003-05-16 | Astrazeneca Ab | New Compounds |
| US20050004133A1 (en) | 2003-06-05 | 2005-01-06 | Makings Lewis R. | Modulators of VR1 receptor |
| KR100707123B1 (ko) | 2003-07-02 | 2007-04-16 | 그뤼넨탈 게엠베하 | 바닐로이드 수용체의 길항제로서 강력한 진통효과를나타내는 4-(메틸설포닐아미노)페닐 동족체 및 이를함유하는 약학적 조성물 |
| DK1708992T3 (da) | 2004-01-22 | 2007-11-05 | Pfizer | Sulfonamidderivater til behandling af sygdomme |
| WO2005073193A1 (en) * | 2004-01-23 | 2005-08-11 | Amgen Inc. | Vanilloid receptor ligands and their use in treatments |
| EP1764095A1 (en) * | 2005-09-20 | 2007-03-21 | Revotar Biopharmaceuticals AG | Novel nitrocatechol derivatives having selectin ligand activity |
| DK1940821T3 (da) | 2005-10-19 | 2013-06-10 | Gruenenthal Gmbh | Nye vanilloid-receptorligander og deres anvendelse til fremstilling af lægemidler. |
| DE102007018151A1 (de) | 2007-04-16 | 2008-10-23 | Günenthal GmbH | Neue Vanilloid-Rezeptor Liganden und ihre Verwendung zur Herstellung von Arzneimitteln |
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2007
- 2007-04-16 DE DE102007018151A patent/DE102007018151A1/de not_active Withdrawn
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2008
- 2008-04-15 MX MX2009011139A patent/MX2009011139A/es active IP Right Grant
- 2008-04-15 CN CN200880020516.5A patent/CN101687799B/zh not_active Expired - Fee Related
- 2008-04-15 RU RU2009142024/04A patent/RU2487120C2/ru not_active IP Right Cessation
- 2008-04-15 WO PCT/EP2008/002994 patent/WO2008125337A2/de not_active Ceased
- 2008-04-15 NZ NZ580381A patent/NZ580381A/en not_active IP Right Cessation
- 2008-04-15 CA CA002683910A patent/CA2683910A1/en not_active Abandoned
- 2008-04-15 KR KR1020097023888A patent/KR101497357B1/ko not_active Expired - Fee Related
- 2008-04-15 US US12/103,198 patent/US8642775B2/en not_active Expired - Fee Related
- 2008-04-15 EP EP08735252A patent/EP2146962A2/de not_active Withdrawn
- 2008-04-15 BR BRPI0810031-4A2A patent/BRPI0810031A2/pt not_active IP Right Cessation
- 2008-04-15 JP JP2010503393A patent/JP5557734B2/ja not_active Expired - Fee Related
- 2008-04-15 NZ NZ599254A patent/NZ599254A/xx not_active IP Right Cessation
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2009
- 2009-10-12 ZA ZA2009/07096A patent/ZA200907096B/en unknown
- 2009-10-14 IL IL201506A patent/IL201506A0/en unknown
- 2009-10-16 CO CO09115659A patent/CO6220938A2/es active IP Right Grant
- 2009-10-16 EC EC2009009693A patent/ECSP099693A/es unknown
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Also Published As
| Publication number | Publication date |
|---|---|
| ZA200907096B (en) | 2013-03-27 |
| BRPI0810031A2 (pt) | 2014-10-14 |
| KR101497357B1 (ko) | 2015-03-02 |
| CN101687799A (zh) | 2010-03-31 |
| NZ599254A (en) | 2013-07-26 |
| AU2008238245A1 (en) | 2008-10-23 |
| RU2487120C2 (ru) | 2013-07-10 |
| RU2009142024A (ru) | 2011-05-27 |
| US8791268B2 (en) | 2014-07-29 |
| CA2683910A1 (en) | 2008-04-16 |
| US20110184020A1 (en) | 2011-07-28 |
| EP2146962A2 (de) | 2010-01-27 |
| WO2008125337A3 (de) | 2009-02-26 |
| NZ580381A (en) | 2012-05-25 |
| US8642775B2 (en) | 2014-02-04 |
| ECSP099693A (es) | 2009-11-30 |
| CO6220938A2 (es) | 2010-11-19 |
| JP5557734B2 (ja) | 2014-07-23 |
| JP2010523726A (ja) | 2010-07-15 |
| WO2008125337A2 (de) | 2008-10-23 |
| US20080262039A1 (en) | 2008-10-23 |
| CN101687799B (zh) | 2014-07-23 |
| KR20100016594A (ko) | 2010-02-12 |
| DE102007018151A1 (de) | 2008-10-23 |
| IL201506A0 (en) | 2010-05-31 |
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