WO2008059339A3 - Isoquinoline derivatives as vanilloid receptor modulators - Google Patents
Isoquinoline derivatives as vanilloid receptor modulators Download PDFInfo
- Publication number
- WO2008059339A3 WO2008059339A3 PCT/IB2007/003457 IB2007003457W WO2008059339A3 WO 2008059339 A3 WO2008059339 A3 WO 2008059339A3 IB 2007003457 W IB2007003457 W IB 2007003457W WO 2008059339 A3 WO2008059339 A3 WO 2008059339A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- isoquinoline derivatives
- vanilloid receptor
- receptor modulators
- vanilloid
- derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
- C07D407/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
Abstract
The present invention relates to substituted isoquinoline derivatives of formula I, which can be used as vanilloid receptor ligands, methods of treating diseases, condition and/or disorders modulated by vanilloid receptors with them, and processes for preparing them.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IN1884MU2006 | 2006-11-13 | ||
IN1884/MUM/2006 | 2006-11-13 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2008059339A2 WO2008059339A2 (en) | 2008-05-22 |
WO2008059339A3 true WO2008059339A3 (en) | 2008-07-24 |
Family
ID=39310968
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/IB2007/003457 WO2008059339A2 (en) | 2006-11-13 | 2007-11-12 | Isoquinoline derivatives as vanilloid receptor modulators |
Country Status (1)
Country | Link |
---|---|
WO (1) | WO2008059339A2 (en) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2010023512A1 (en) * | 2008-08-28 | 2010-03-04 | Matrix Laboratories Ltd. | Novel vanilloid receptor modulators, process for their preparation and pharmaceutical compositions containing them |
WO2010026128A1 (en) * | 2008-09-02 | 2010-03-11 | Glaxo Group Limited | N-(3-methyl-5-isoquinolinyl)-n'-((3r)-1-[5-(trifluoromethyl)-2-pyridinyl]-3-pyrrolidinyl) urea for the treatment of rhinitis |
CN102186836A (en) * | 2008-10-17 | 2011-09-14 | 雅培制药有限公司 | Trpv1 antagonists |
WO2010045402A1 (en) * | 2008-10-17 | 2010-04-22 | Abbott Laboratories | Trpv1 antagonists |
CN103635458B (en) | 2011-03-25 | 2016-10-19 | 艾伯维公司 | TRPV1 antagonist |
US8859584B2 (en) | 2011-12-19 | 2014-10-14 | Abbvie, Inc. | TRPV1 antagonists |
US8969325B2 (en) | 2011-12-19 | 2015-03-03 | Abbvie Inc. | TRPV1 antagonists |
US8796328B2 (en) | 2012-06-20 | 2014-08-05 | Abbvie Inc. | TRPV1 antagonists |
TW201711999A (en) | 2015-09-03 | 2017-04-01 | 佛瑪治療公司 | [6,6] fused bicyclic HDAC8 inhibitors |
RU2755206C1 (en) | 2020-05-20 | 2021-09-14 | Федеральное государственное бюджетное учреждение науки Тихоокеанский институт биоорганической химии им. Г.Б. Елякова Дальневосточного отделения Российской академии наук (ТИБОХ ДВО РАН) | Agent with prolonged analgesic action and medicinal product based thereon |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2003080578A1 (en) * | 2002-03-22 | 2003-10-02 | Merck Sharp & Dohme Limited | Heteroaromatic urea derivatives as vr-1 receptor modulators for treating pain |
WO2006065484A2 (en) * | 2004-11-24 | 2006-06-22 | Abbott Laboratories | Chromanylurea compounds that inhibit vanilloid receptor subtype 1 (vr1) receptor and uses thereof |
-
2007
- 2007-11-12 WO PCT/IB2007/003457 patent/WO2008059339A2/en active Application Filing
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2003080578A1 (en) * | 2002-03-22 | 2003-10-02 | Merck Sharp & Dohme Limited | Heteroaromatic urea derivatives as vr-1 receptor modulators for treating pain |
WO2006065484A2 (en) * | 2004-11-24 | 2006-06-22 | Abbott Laboratories | Chromanylurea compounds that inhibit vanilloid receptor subtype 1 (vr1) receptor and uses thereof |
Also Published As
Publication number | Publication date |
---|---|
WO2008059339A2 (en) | 2008-05-22 |
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