MX2009010790A - Derivados de heteroarilo biciclico fusionados. - Google Patents

Derivados de heteroarilo biciclico fusionados.

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Publication number
MX2009010790A
MX2009010790A MX2009010790A MX2009010790A MX2009010790A MX 2009010790 A MX2009010790 A MX 2009010790A MX 2009010790 A MX2009010790 A MX 2009010790A MX 2009010790 A MX2009010790 A MX 2009010790A MX 2009010790 A MX2009010790 A MX 2009010790A
Authority
MX
Mexico
Prior art keywords
group
bicyclic heteroaryl
fused bicyclic
optionally substituted
independently selected
Prior art date
Application number
MX2009010790A
Other languages
English (en)
Inventor
Kousei Shimada
Yoshiyuki Onishi
Makoto Mori
Eri Tokumaru
Original Assignee
Daiichi Sankyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Daiichi Sankyo Co Ltd filed Critical Daiichi Sankyo Co Ltd
Publication of MX2009010790A publication Critical patent/MX2009010790A/es

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    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
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    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
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Abstract

Un derivado de heteroarilo bicíclico fusionado novedoso, el cual tiene un buen efecto hipoglucémico y trata enfermedades y trastornos metabólicos de azúcar y lípidos mediante receptor activado por proliferador de peroxisoma (PPAR) y y/o evita la generación de estas enfermedades, o una sal farmacológicamente aceptable del mismo. Un compuesto que tiene la siguiente fórmula general (I) o una sal farmacológicamente aceptable del mismo. [Química para fórmula 1] (I) en donde R1 representa un grupo C1-6 alquilo, un grupo C6-10 arilo opcionalmente substituido por uno a cinco grupos independientemente seleccionados del grupo substituyente a, etc. R2 representa un grupo C1-6 alquilo, R1 representa un grupo C6-10 arilo opcionalmente substituido por de 1 a 5 grupos independientemente seleccionado del grupo substituyente a, etc. Q representa un grupo representado por la fórmula -CH- o un átomo de nitrógeno, y el grupo substituyente a incluye un átomo de halógeno, un grupo C1-6 alquilo, un grupo C1-6 hidroxialquilo, etc.
MX2009010790A 2007-04-05 2008-04-02 Derivados de heteroarilo biciclico fusionados. MX2009010790A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2007099413 2007-04-05
PCT/JP2008/056541 WO2008126732A1 (ja) 2007-04-05 2008-04-02 縮合二環式ヘテロアリール誘導体

Publications (1)

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MX2009010790A true MX2009010790A (es) 2009-10-29

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MX2009010790A MX2009010790A (es) 2007-04-05 2008-04-02 Derivados de heteroarilo biciclico fusionados.

Country Status (18)

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US (2) US20100048564A1 (es)
EP (1) EP2138484B1 (es)
JP (1) JP5294419B2 (es)
KR (1) KR20090126286A (es)
CN (1) CN101679298B (es)
AU (1) AU2008239179B2 (es)
BR (1) BRPI0809643A2 (es)
CA (1) CA2683089A1 (es)
CO (1) CO6251366A2 (es)
ES (1) ES2550479T3 (es)
IL (1) IL201326A0 (es)
MX (1) MX2009010790A (es)
MY (1) MY148434A (es)
NZ (1) NZ580588A (es)
RU (1) RU2456276C2 (es)
TW (2) TW200906400A (es)
WO (1) WO2008126732A1 (es)
ZA (1) ZA200907510B (es)

Families Citing this family (17)

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Publication number Priority date Publication date Assignee Title
RU2480463C1 (ru) * 2009-03-05 2013-04-27 Дайити Санкио Компани, Лимитед Пиридилокси производные, полезные в качестве активатора/модулятора гамма-рецептора, активируемого пролифератором пероксисом (ppar) гамма
EP2505587A1 (en) * 2009-11-26 2012-10-03 Daiichi Sankyo Company, Limited Method for manufacturing a 6-substituted-1-methyl-1h-benzimidazole derivative, and manufacturing intermediate from said method
WO2011107494A1 (de) 2010-03-03 2011-09-09 Sanofi Neue aromatische glykosidderivate, diese verbindungen enthaltende arzneimittel und deren verwendung
US8933024B2 (en) 2010-06-18 2015-01-13 Sanofi Azolopyridin-3-one derivatives as inhibitors of lipases and phospholipases
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