MX2009006113A - Proceso catalitico para hidrogenacion asimetrica. - Google Patents
Proceso catalitico para hidrogenacion asimetrica.Info
- Publication number
- MX2009006113A MX2009006113A MX2009006113A MX2009006113A MX2009006113A MX 2009006113 A MX2009006113 A MX 2009006113A MX 2009006113 A MX2009006113 A MX 2009006113A MX 2009006113 A MX2009006113 A MX 2009006113A MX 2009006113 A MX2009006113 A MX 2009006113A
- Authority
- MX
- Mexico
- Prior art keywords
- aryl
- halogen
- alkyl
- term
- alkyloxy
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 2
- 229910052736 halogen Inorganic materials 0.000 abstract 4
- 150000002367 halogens Chemical class 0.000 abstract 4
- 125000003545 alkoxy group Chemical group 0.000 abstract 3
- 125000000217 alkyl group Chemical group 0.000 abstract 3
- 125000003118 aryl group Chemical group 0.000 abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 2
- 125000004435 hydrogen atom Chemical class [H]* 0.000 abstract 2
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 2
- ZCYVEMRRCGMTRW-UHFFFAOYSA-N 7553-56-2 Chemical compound [I] ZCYVEMRRCGMTRW-UHFFFAOYSA-N 0.000 abstract 1
- WKBOTKDWSSQWDR-UHFFFAOYSA-N Bromine atom Chemical compound [Br] WKBOTKDWSSQWDR-UHFFFAOYSA-N 0.000 abstract 1
- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 abstract 1
- PXGOKWXKJXAPGV-UHFFFAOYSA-N Fluorine Chemical compound FF PXGOKWXKJXAPGV-UHFFFAOYSA-N 0.000 abstract 1
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical group [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 abstract 1
- 239000005864 Sulphur Chemical group 0.000 abstract 1
- 125000004453 alkoxycarbonyl group Chemical group 0.000 abstract 1
- 125000003282 alkyl amino group Chemical group 0.000 abstract 1
- 125000003806 alkyl carbonyl amino group Chemical group 0.000 abstract 1
- 238000009876 asymmetric hydrogenation reaction Methods 0.000 abstract 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical group [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
- GDTBXPJZTBHREO-UHFFFAOYSA-N bromine Substances BrBr GDTBXPJZTBHREO-UHFFFAOYSA-N 0.000 abstract 1
- 229910052794 bromium Inorganic materials 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 239000003054 catalyst Substances 0.000 abstract 1
- 229910052801 chlorine Inorganic materials 0.000 abstract 1
- 239000000460 chlorine Substances 0.000 abstract 1
- 125000004663 dialkyl amino group Chemical group 0.000 abstract 1
- 229910052731 fluorine Inorganic materials 0.000 abstract 1
- 239000011737 fluorine Substances 0.000 abstract 1
- 125000001183 hydrocarbyl group Chemical group 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- -1 hydroxycarbonyl groups Chemical group 0.000 abstract 1
- 229910052740 iodine Inorganic materials 0.000 abstract 1
- 239000011630 iodine Substances 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 125000000325 methylidene group Chemical group [H]C([H])=* 0.000 abstract 1
- 125000001624 naphthyl group Chemical group 0.000 abstract 1
- 239000001301 oxygen Chemical group 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Catalysts (AREA)
- Pyrane Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US86960506P | 2006-12-12 | 2006-12-12 | |
| PCT/GB2007/004756 WO2008071951A2 (en) | 2006-12-12 | 2007-12-12 | Catalytic process for asymmetric hydrogenation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2009006113A true MX2009006113A (es) | 2009-07-17 |
Family
ID=39247380
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2009006113A MX2009006113A (es) | 2006-12-12 | 2007-12-12 | Proceso catalitico para hidrogenacion asimetrica. |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US8546571B2 (enExample) |
| EP (1) | EP2102182B1 (enExample) |
| JP (1) | JP5372771B2 (enExample) |
| KR (1) | KR20090091326A (enExample) |
| CN (1) | CN101627023A (enExample) |
| AR (1) | AR064308A1 (enExample) |
| AU (1) | AU2007331340A1 (enExample) |
| BR (1) | BRPI0718351A2 (enExample) |
| CA (1) | CA2671830C (enExample) |
| ES (1) | ES2483718T3 (enExample) |
| MX (1) | MX2009006113A (enExample) |
| NO (1) | NO20092259L (enExample) |
| PT (1) | PT103901B (enExample) |
| RU (1) | RU2009126571A (enExample) |
| WO (1) | WO2008071951A2 (enExample) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2009126571A (ru) | 2006-12-12 | 2011-01-20 | Биал-Портела Энд Ка, С.А. (Pt) | Каталитический способ асимметричной гидрогенизации |
| GB0709695D0 (en) * | 2007-05-21 | 2007-06-27 | Portela & Ca Sa | Process |
| TW200927740A (en) * | 2007-11-13 | 2009-07-01 | Bial Portela & Ca Sa | Process |
| AR070841A1 (es) * | 2008-03-13 | 2010-05-05 | Bial Portela & Ca Sa | Proceso de hidrogenacion catalitica asimetrica |
| ES2429120T3 (es) * | 2008-03-19 | 2013-11-13 | Bial-Portela & Ca, S.A. | Hidrogenación catalítica asimétrica |
| AR071632A1 (es) * | 2008-05-06 | 2010-06-30 | Bial Portela & Ca Sa | Proceso catalitico para hidrogenacion asimetrica en la sintesis de inhibidores de la dopamina-beta-hidroxilasa" |
| CN111196759B (zh) * | 2018-11-16 | 2023-03-24 | 上海博志研新药物技术有限公司 | 盐酸西那卡塞及其中间体的制备方法 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5202474A (en) | 1989-06-22 | 1993-04-13 | Monsanto Company | Asymmetric catalytic hydrogenation of α-arylpropenoic acids |
| US5420151A (en) | 1989-12-22 | 1995-05-30 | Aktiebolaget Astra | Chroman derivatives |
| BR9507517A (pt) | 1994-04-26 | 1997-09-16 | Syntex Inc | Derivados de benzocicloalquilazotetiona |
| US5886182A (en) * | 1997-12-10 | 1999-03-23 | The Hong Kong Polytechnic University | Chiral pyridylphosphines and their application in asymmetric catalytic hydrogenation of 2-arylpropenoic acids |
| US7125904B2 (en) | 2002-10-11 | 2006-10-24 | Portela & C.A., S.A. | Peripherally-selective inhibitors of dopamine-β-hydroxylase and method of their preparation |
| GB0316439D0 (en) * | 2003-07-15 | 2003-08-20 | Johnson Matthey Plc | Catalysts |
| RU2009126571A (ru) | 2006-12-12 | 2011-01-20 | Биал-Портела Энд Ка, С.А. (Pt) | Каталитический способ асимметричной гидрогенизации |
-
2007
- 2007-12-12 RU RU2009126571/04A patent/RU2009126571A/ru not_active Application Discontinuation
- 2007-12-12 CN CN200780051168A patent/CN101627023A/zh active Pending
- 2007-12-12 EP EP07848500.0A patent/EP2102182B1/en not_active Not-in-force
- 2007-12-12 BR BRPI0718351A patent/BRPI0718351A2/pt not_active IP Right Cessation
- 2007-12-12 ES ES07848500.0T patent/ES2483718T3/es active Active
- 2007-12-12 KR KR1020097014315A patent/KR20090091326A/ko not_active Withdrawn
- 2007-12-12 PT PT103901A patent/PT103901B/pt active IP Right Grant
- 2007-12-12 AU AU2007331340A patent/AU2007331340A1/en not_active Abandoned
- 2007-12-12 MX MX2009006113A patent/MX2009006113A/es not_active Application Discontinuation
- 2007-12-12 US US12/518,416 patent/US8546571B2/en not_active Expired - Fee Related
- 2007-12-12 WO PCT/GB2007/004756 patent/WO2008071951A2/en not_active Ceased
- 2007-12-12 CA CA2671830A patent/CA2671830C/en active Active
- 2007-12-12 JP JP2009540851A patent/JP5372771B2/ja not_active Expired - Fee Related
- 2007-12-12 AR ARP070105572A patent/AR064308A1/es unknown
-
2009
- 2009-06-11 NO NO20092259A patent/NO20092259L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| AU2007331340A1 (en) | 2008-06-19 |
| KR20090091326A (ko) | 2009-08-27 |
| US8546571B2 (en) | 2013-10-01 |
| ES2483718T3 (es) | 2014-08-07 |
| BRPI0718351A2 (pt) | 2019-09-24 |
| JP5372771B2 (ja) | 2013-12-18 |
| WO2008071951A3 (en) | 2008-10-02 |
| EP2102182A2 (en) | 2009-09-23 |
| AR064308A1 (es) | 2009-03-25 |
| PT103901B (pt) | 2012-03-01 |
| RU2009126571A (ru) | 2011-01-20 |
| US20100036127A1 (en) | 2010-02-11 |
| EP2102182B1 (en) | 2014-04-23 |
| JP2010512379A (ja) | 2010-04-22 |
| CA2671830C (en) | 2019-03-19 |
| CN101627023A (zh) | 2010-01-13 |
| NO20092259L (no) | 2009-06-25 |
| WO2008071951A2 (en) | 2008-06-19 |
| PT103901A (pt) | 2008-06-12 |
| CA2671830A1 (en) | 2008-06-19 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| HH | Correction or change in general | ||
| FA | Abandonment or withdrawal |