MX2007004373A - Metodo para prevenir y tratar el remoldeo de las vias respiratorias e inflamacion pulmonar utilizando antagonistas de receptor adenosina a2b. - Google Patents

Info

Publication number

MX2007004373A

MX2007004373A MX2007004373A MX2007004373A MX2007004373A MX 2007004373 A MX2007004373 A MX 2007004373A MX 2007004373 A MX2007004373 A MX 2007004373A MX 2007004373 A MX2007004373 A MX 2007004373A MX 2007004373 A MX2007004373 A MX 2007004373A

Authority

MX

Mexico

Prior art keywords

optionally substituted

propyl

methyl

dione

formula

Prior art date

2004-10-15

Links

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• 238000000034 method Methods 0.000 title claims abstract description 129
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• 239000000296 purinergic P1 receptor antagonist Substances 0.000 title abstract description 3
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• 208000006545 Chronic Obstructive Pulmonary Disease Diseases 0.000 claims abstract 2
• 150000001875 compounds Chemical class 0.000 claims description 232
• -1 5- (2-methoxyphenyl) - (1, 2,4-oxadiazol-3-yl) Chemical group 0.000 claims description 183
• 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims description 69
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• 125000001072 heteroaryl group Chemical group 0.000 claims description 47
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• 125000000959 isobutyl group Chemical group [H]C([H])([H])C([H])(C([H])([H])[H])C([H])([H])* 0.000 claims description 26
• 125000002947 alkylene group Chemical group 0.000 claims description 25
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• SIOXPEMLGUPBBT-UHFFFAOYSA-N Picolinic acid Natural products OC(=O)C1=CC=CC=N1 SIOXPEMLGUPBBT-UHFFFAOYSA-N 0.000 claims 1
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• 125000000842 isoxazolyl group Chemical group 0.000 claims 1
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