MX12317A - Derivados de ester nitrico y procedimiento para suobtencion. - Google Patents
Derivados de ester nitrico y procedimiento para suobtencion.Info
- Publication number
- MX12317A MX12317A MX1231788A MX1231788A MX12317A MX 12317 A MX12317 A MX 12317A MX 1231788 A MX1231788 A MX 1231788A MX 1231788 A MX1231788 A MX 1231788A MX 12317 A MX12317 A MX 12317A
- Authority
- MX
- Mexico
- Prior art keywords
- alkyl
- alkylene
- suitable substituent
- subset
- derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D277/26—Radicals substituted by sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/30—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D263/34—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D277/30—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Plural Heterocyclic Compounds (AREA)
- Saccharide Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB878717068A GB8717068D0 (en) | 1987-07-20 | 1987-07-20 | Nitric ester derivative |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX12317A true MX12317A (es) | 1993-09-01 |
Family
ID=10620954
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX1231788A MX12317A (es) | 1987-07-20 | 1988-07-18 | Derivados de ester nitrico y procedimiento para suobtencion. |
Country Status (19)
| Country | Link |
|---|---|
| US (2) | US4923886A (enExample) |
| EP (1) | EP0300400B1 (enExample) |
| JP (1) | JPH0228167A (enExample) |
| KR (1) | KR890002067A (enExample) |
| CN (1) | CN1021046C (enExample) |
| AT (1) | ATE102928T1 (enExample) |
| AU (1) | AU623858B2 (enExample) |
| DE (1) | DE3888415T2 (enExample) |
| DK (1) | DK375988A (enExample) |
| FI (1) | FI883402L (enExample) |
| GB (1) | GB8717068D0 (enExample) |
| HU (1) | HU203227B (enExample) |
| IL (1) | IL86959A (enExample) |
| MX (1) | MX12317A (enExample) |
| NO (1) | NO172049C (enExample) |
| PH (1) | PH24481A (enExample) |
| PT (1) | PT88019B (enExample) |
| SU (2) | SU1706388A3 (enExample) |
| ZA (1) | ZA884987B (enExample) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3941438A1 (de) * | 1989-12-15 | 1991-06-20 | Hoechst Ag | Neue 2-substituierte 4-(3-alkyl-5-tert.-butyl-4-hydroxy-phenyl)-thiazole, verfahren zu ihrer herstellung, die sie enthaltenden arzneimittel und ihre verwendung |
| IT1243367B (it) * | 1990-07-26 | 1994-06-10 | Italfarmaco Spa | Derivati acidi benzoici sostituiti ad attivita' cardiovascolare |
| US5298516A (en) * | 1991-03-27 | 1994-03-29 | Sankyo Company, Limited | Thiazolidone compounds and method of using the same as a vasodilator |
| JP3454531B2 (ja) * | 1991-11-07 | 2003-10-06 | 三共株式会社 | ニトロキシアルキルアミド誘導体 |
| IT1256450B (it) * | 1992-11-26 | 1995-12-05 | Soldato Piero Del | Esteri nitrici con attivita' farmacologica e procedimento per la loro preparazione |
| ES2161916T3 (es) * | 1994-12-15 | 2001-12-16 | Sankyo Co | Derivados de la tiazolidinona o de la oxazolidinona para el tratamiento de la angina de pecho y composiciones que las contienen como ingrediente activo. |
| US5925658A (en) * | 1995-03-02 | 1999-07-20 | Sankyo Company, Limited | Optically active thiazolidinone derivative |
| WO1996026931A1 (en) * | 1995-03-02 | 1996-09-06 | Sankyo Company, Limited | Optically active thiazolidinone derivatives |
| IL120531A (en) | 1997-03-26 | 2006-12-31 | Yissum Res Dev Co | Nitric oxide donors and pharmaceutical compositions containing them |
| EP2308833A3 (en) | 1999-04-15 | 2011-09-28 | Bristol-Myers Squibb Company | Cyclic protein tyrosine kinase inhibitors |
| JP4216193B2 (ja) * | 2001-11-27 | 2009-01-28 | エフ．ホフマン−ラ ロシュ アーゲー | ベンゾチアゾール誘導体 |
| US6624163B2 (en) * | 2001-11-29 | 2003-09-23 | Hoffman-La Roche Inc. | Benzothiazole derivatives |
| US6933308B2 (en) * | 2002-12-20 | 2005-08-23 | Bristol-Myers Squibb Company | Aminoalkyl thiazole derivatives as KCNQ modulators |
| US7273866B2 (en) * | 2002-12-20 | 2007-09-25 | Bristol-Myers Squibb Company | 2-aryl thiazole derivatives as KCNQ modulators |
| US7968575B2 (en) * | 2004-05-05 | 2011-06-28 | Renopharm Ltd. | Nitric oxide donors and uses thereof |
| WO2005105765A1 (en) * | 2004-05-05 | 2005-11-10 | Renopharm Ltd. | Nitric oxide donors and uses thereof |
| US8134010B2 (en) * | 2004-05-05 | 2012-03-13 | Renopharm Ltd. | Thiazole-based nitric oxide donors having aryl substituent(s) and uses thereof |
| DE102009037555A1 (de) * | 2009-08-13 | 2011-03-03 | Synovo Gmbh | Ein neuartiges, schonendes Verfahren zur direkten Nitrierung von Hydroxyl-, Thiol- und Aminogruppen in organischen Molekülen mittels in situ generiertem Kohlensäuredinitrat |
| KR101045041B1 (ko) * | 2009-10-27 | 2011-06-28 | (주)에스엠이엔지 | 봉합침 제조방법 |
| CA2839390C (en) * | 2011-10-24 | 2015-09-15 | Nicox S.A. | Quinone based nitric oxide donating compounds |
| AU2013304942A1 (en) * | 2012-08-23 | 2015-03-05 | Cardiolynx Ag | Extended release compositions of an aminoalkyl nitrate |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4200640A (en) * | 1976-04-02 | 1980-04-29 | Chugai Seiyaku Kabushiki Kaisha | Nitric ester of N-(2-hydroxyethyl)nicotinamide and pharmaceutical use |
| DE3244178A1 (de) * | 1982-11-30 | 1984-05-30 | Bayer Ag, 5090 Leverkusen | 1,4-dihydropyridinderivate, verfahren zu ihrer herstellung sowie ihre verwendung in arzneimitteln |
| DE3433383A1 (de) * | 1984-09-12 | 1986-03-20 | Boehringer Mannheim Gmbh, 6800 Mannheim | Neue phenyl-acetonitril-derivate |
-
1987
- 1987-07-20 GB GB878717068A patent/GB8717068D0/en active Pending
-
1988
- 1988-06-30 US US07/213,623 patent/US4923886A/en not_active Expired - Fee Related
- 1988-07-01 PH PH37159A patent/PH24481A/en unknown
- 1988-07-03 IL IL86959A patent/IL86959A/xx unknown
- 1988-07-06 DK DK375988A patent/DK375988A/da not_active Application Discontinuation
- 1988-07-11 ZA ZA884987A patent/ZA884987B/xx unknown
- 1988-07-15 JP JP63177362A patent/JPH0228167A/ja active Granted
- 1988-07-15 PT PT88019A patent/PT88019B/pt not_active IP Right Cessation
- 1988-07-16 EP EP88111490A patent/EP0300400B1/en not_active Expired - Lifetime
- 1988-07-16 DE DE3888415T patent/DE3888415T2/de not_active Expired - Fee Related
- 1988-07-16 AT AT88111490T patent/ATE102928T1/de not_active IP Right Cessation
- 1988-07-18 MX MX1231788A patent/MX12317A/es unknown
- 1988-07-18 FI FI883402A patent/FI883402L/fi not_active Application Discontinuation
- 1988-07-19 CN CN88104473A patent/CN1021046C/zh not_active Expired - Fee Related
- 1988-07-19 NO NO883208A patent/NO172049C/no unknown
- 1988-07-19 KR KR1019880008995A patent/KR890002067A/ko not_active Withdrawn
- 1988-07-19 SU SU884356158A patent/SU1706388A3/ru active
- 1988-07-19 HU HU883775A patent/HU203227B/hu not_active IP Right Cessation
- 1988-07-20 AU AU19199/88A patent/AU623858B2/en not_active Ceased
-
1989
- 1989-06-19 SU SU894614353A patent/SU1760984A3/ru active
-
1990
- 1990-03-16 US US07/494,545 patent/US5010093A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| NO883208D0 (no) | 1988-07-19 |
| DE3888415D1 (de) | 1994-04-21 |
| PT88019B (pt) | 1995-03-01 |
| US5010093A (en) | 1991-04-23 |
| PT88019A (pt) | 1989-06-30 |
| JPH0228167A (ja) | 1990-01-30 |
| EP0300400B1 (en) | 1994-03-16 |
| FI883402A0 (fi) | 1988-07-18 |
| NO172049B (no) | 1993-02-22 |
| KR890002067A (ko) | 1989-04-07 |
| NO883208L (no) | 1989-01-23 |
| IL86959A0 (en) | 1988-12-30 |
| HU203227B (en) | 1991-06-28 |
| NO172049C (no) | 1993-06-02 |
| ZA884987B (en) | 1989-05-30 |
| GB8717068D0 (en) | 1987-08-26 |
| AU623858B2 (en) | 1992-05-28 |
| AU1919988A (en) | 1989-01-27 |
| US4923886A (en) | 1990-05-08 |
| DK375988A (da) | 1989-01-21 |
| DK375988D0 (da) | 1988-07-06 |
| PH24481A (en) | 1990-07-18 |
| CN1031226A (zh) | 1989-02-22 |
| SU1760984A3 (ru) | 1992-09-07 |
| HUT47551A (en) | 1989-03-28 |
| IL86959A (en) | 1992-12-01 |
| JPH0331709B2 (enExample) | 1991-05-08 |
| SU1706388A3 (ru) | 1992-01-15 |
| FI883402A7 (fi) | 1989-01-21 |
| ATE102928T1 (de) | 1994-04-15 |
| FI883402L (fi) | 1989-01-21 |
| CN1021046C (zh) | 1993-06-02 |
| DE3888415T2 (de) | 1994-07-14 |
| EP0300400A1 (en) | 1989-01-25 |
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