MEP2008A - Postupak za pripremanje escitaloprama - Google Patents

Postupak za pripremanje escitaloprama

Info

Publication number
MEP2008A
MEP2008A MEP-20/08A MEP2008A MEP2008A ME P2008 A MEP2008 A ME P2008A ME P2008 A MEP2008 A ME P2008A ME P2008 A MEP2008 A ME P2008A
Authority
ME
Montenegro
Prior art keywords
escitalopram
preparation
citalopram
novel
chiral
Prior art date
Application number
MEP-20/08A
Other languages
Bosnian (bs)
English (en)
Inventor
Somer Michael Bech
Ole Nielsen
Hans Petersen
Helen Ahmadian
Henrik Pedersen
Peter Broesen
Fiona A Geiser
James Lee
Geoffey Cox
Oliver Dapremont
Christina Suteu
Sebastian P Assenza
Shankar Hariharan
Usha Nair
Original Assignee
Lundbeck & Co As H
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27222518&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MEP2008(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Lundbeck & Co As H filed Critical Lundbeck & Co As H
Publication of MEP2008A publication Critical patent/MEP2008A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C215/00Compounds containing amino and hydroxy groups bound to the same carbon skeleton
    • C07C215/02Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C215/22Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated
    • C07C215/28Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated and containing six-membered aromatic rings
    • C07C215/30Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated and containing six-membered aromatic rings containing hydroxy groups and carbon atoms of six-membered aromatic rings bound to the same carbon atom of the carbon skeleton
    • C07C215/32Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated and containing six-membered aromatic rings containing hydroxy groups and carbon atoms of six-membered aromatic rings bound to the same carbon atom of the carbon skeleton containing hydroxy groups and carbon atoms of two six-membered aromatic rings bound to the same carbon atom of the carbon skeleton
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/87Benzo [c] furans; Hydrogenated benzo [c] furans

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychiatry (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
MEP-20/08A 2001-07-13 2002-07-12 Postupak za pripremanje escitaloprama MEP2008A (xx)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DKPA200101101 2001-07-13
DKPA200101851 2001-12-11
DKPA200101852 2001-12-11
PCT/DK2002/000491 WO2003006449A1 (fr) 2001-07-13 2002-07-12 Procede de preparation d'escitalopram

Publications (1)

Publication Number Publication Date
MEP2008A true MEP2008A (xx) 2010-02-10

Family

ID=27222518

Family Applications (1)

Application Number Title Priority Date Filing Date
MEP-20/08A MEP2008A (xx) 2001-07-13 2002-07-12 Postupak za pripremanje escitaloprama

Country Status (29)

Country Link
US (2) US20050065207A1 (fr)
EP (1) EP1409472A1 (fr)
JP (1) JP2004538276A (fr)
KR (4) KR20080108628A (fr)
CN (2) CN101265199A (fr)
AR (1) AR034759A1 (fr)
AU (1) AU2009200448A1 (fr)
BG (1) BG108572A (fr)
BR (1) BR0210817A (fr)
CA (1) CA2451124C (fr)
CO (1) CO5550496A2 (fr)
EA (1) EA014823B1 (fr)
HK (1) HK1069386A1 (fr)
HR (1) HRPK20031074B3 (fr)
HU (1) HUP0401451A3 (fr)
IL (1) IL159183A0 (fr)
IS (1) IS7064A (fr)
ME (1) MEP2008A (fr)
MX (1) MXPA04000205A (fr)
MY (1) MY144333A (fr)
NO (1) NO328561B1 (fr)
PE (1) PE20030253A1 (fr)
PL (1) PL366383A1 (fr)
RS (1) RS1804A (fr)
TW (1) TWI268926B (fr)
UA (1) UA84258C2 (fr)
UY (1) UY27379A1 (fr)
WO (1) WO2003006449A1 (fr)
ZA (1) ZA200309471B (fr)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PE20040991A1 (es) 2002-08-12 2004-12-27 Lundbeck & Co As H Separacion de intermediarios para la preparacion de escitalopram
EP1581483B1 (fr) 2002-12-23 2012-06-06 H. Lundbeck A/S Procede de preparation de citalopram diol racemique et/ou s- ou r-citalopram diols ainsi qu'utilisation de tels diols pour la preparation de citalopram racemique, r-citalopram et/ou s-citalopram
FR2853650B1 (fr) * 2003-04-10 2006-07-07 Merck Sante Sas Procede de dedoublement d'amines utiles pour le traitement de desordres associes au syndrome d'insulino-resistance
ES2228274B1 (es) * 2003-09-24 2006-06-01 Astur Pharma, S.A. Sintesis quimioenzimatica de (+)-citalopram y (-)-citalopram.
TWI339651B (en) * 2004-02-12 2011-04-01 Lundbeck & Co As H Method for the separation of intermediates which may be used for the preparation of escitalopram
US20050196453A1 (en) 2004-03-05 2005-09-08 H. Lundbeck A/S Crystalline composition containing escitalopram
ITMI20040717A1 (it) 2004-04-09 2004-07-09 Adorkem Technology Spa Procedimento chemo-enzimatico per la preparazione dell'escitalopram
JP2006008603A (ja) * 2004-06-25 2006-01-12 Sumitomo Chemical Co Ltd 光学活性シタロプラムの製造方法、その中間体およびその製造方法
KR101166280B1 (ko) 2004-08-23 2013-11-27 썬 파마 글로벌 에프제트이 시탈로프램 및 에난티오머의 제조 방법
US7989645B2 (en) * 2004-08-23 2011-08-02 Sun Pharma Global Fze Process for preparation of citalopram and enantiomers
ITMI20041872A1 (it) * 2004-10-01 2005-01-01 Adorkem Technology Spa Processo per la preparazione di citalopram e di scitalopram
EP1877394A1 (fr) * 2005-04-04 2008-01-16 Jubilant Organosys Limited Processus de preparation d'escitalopram ou de ses sels d'addition acides
US7834201B2 (en) 2005-06-22 2010-11-16 H. Lundbeck A/S Crystalline base of escitalopram and orodispersible tablets comprising escitalopram base
TWI347942B (en) 2005-06-22 2011-09-01 Lundbeck & Co As H Crystalline base of escitalopram and orodispersible tablets comprising escitalopram base
CA2625835A1 (fr) 2005-10-14 2007-05-10 Forest Laboratories, Inc. Procedes de traitement de troubles du systeme nerveux central avec une combinaison de faible dose d'escitaloprame et de bupropion
CN101309924A (zh) * 2005-11-14 2008-11-19 H.隆德贝克有限公司 依地普仑的制备方法
GB0601286D0 (en) 2006-01-23 2006-03-01 Sandoz Ag Asymmetric synthesis
EP1988086B2 (fr) 2007-04-23 2014-11-26 Synthon B.V. Processus pour résoudre un citalopram
EP2017271A1 (fr) 2007-07-06 2009-01-21 Aurobindo Pharma Limited Procédé de préparation d'escitalopram
US8022232B2 (en) 2007-09-11 2011-09-20 H. Lundbeck A/S Method for manufacture of escitalopram
FI121570B (fi) 2007-09-11 2011-01-14 Lundbeck & Co As H Menetelmä essitalopraamin valmistamiseksi
CN106568863A (zh) * 2016-11-04 2017-04-19 北京万全德众医药生物技术有限公司 一种用高效液相色谱法分离测定草酸艾司西肽普兰中间体光学异构体的方法
CN107941962A (zh) * 2017-12-28 2018-04-20 北京和合医学诊断技术股份有限公司 检测血液中艾司西酞普兰药物含量的液相色谱分析方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1526331A (en) * 1976-01-14 1978-09-27 Kefalas As Phthalanes
GB8419963D0 (en) * 1984-08-06 1984-09-12 Lundbeck & Co As H Intermediate compound and method
GB8814057D0 (en) * 1988-06-14 1988-07-20 Lundbeck & Co As H New enantiomers & their isolation
JP3010816B2 (ja) 1991-08-22 2000-02-21 ダイセル化学工業株式会社 光学分割における光学異性体と溶媒との回収方法、溶媒の循環使用方法、および光学異性体の再利用方法
US5514818A (en) * 1993-09-17 1996-05-07 Daicel Chemical Industries, Ltd. Resolution of stereoisomers of aliphatic epoxides
US5889180A (en) * 1997-11-10 1999-03-30 Uop Llc Use of small pore silicas as a support for a chiral stationary phase
NL1017415C1 (nl) * 2000-02-24 2001-05-18 Lundbeck & Co As H Werkwijze voor de bereiding van Citalopram.
US6967259B2 (en) * 2001-09-24 2005-11-22 Pharmachem Technologies Limited Process for the preparation of Citalopram intermediate
US6764200B1 (en) * 2003-01-15 2004-07-20 Hsiang Lan Wu Liu Decorative lantern

Also Published As

Publication number Publication date
KR20100036387A (ko) 2010-04-07
NO328561B1 (no) 2010-03-22
KR20080108629A (ko) 2008-12-15
EA200400177A1 (ru) 2004-06-24
US20110065938A1 (en) 2011-03-17
HUP0401451A3 (en) 2007-05-29
AR034759A1 (es) 2004-03-17
KR100956260B1 (ko) 2010-05-07
BG108572A (bg) 2005-03-31
RS1804A (en) 2006-12-15
CA2451124C (fr) 2009-11-24
UA84258C2 (en) 2008-10-10
PL366383A1 (en) 2005-01-24
NO20040027L (no) 2004-01-05
US20050065207A1 (en) 2005-03-24
CN101265199A (zh) 2008-09-17
WO2003006449A1 (fr) 2003-01-23
EP1409472A1 (fr) 2004-04-21
HRPK20031074B3 (en) 2009-10-31
JP2004538276A (ja) 2004-12-24
MY144333A (en) 2011-08-29
BR0210817A (pt) 2004-06-22
MXPA04000205A (es) 2004-03-18
HRP20031074A2 (en) 2004-04-30
PE20030253A1 (es) 2003-03-19
CO5550496A2 (es) 2005-08-31
EA014823B1 (ru) 2011-02-28
UY27379A1 (es) 2003-02-28
IS7064A (is) 2003-12-04
HK1069386A1 (en) 2005-05-20
CA2451124A1 (fr) 2003-01-23
TWI268926B (en) 2006-12-21
AU2009200448A1 (en) 2009-03-05
CN1527825A (zh) 2004-09-08
ZA200309471B (en) 2004-12-06
KR20080108628A (ko) 2008-12-15
IL159183A0 (en) 2004-06-01
HUP0401451A2 (hu) 2004-11-29
CN100457746C (zh) 2009-02-04
KR20040030046A (ko) 2004-04-08

Similar Documents

Publication Publication Date Title
HK1069386A1 (en) Method for the preparation of escitalopram
MY118906A (en) Novel process and intermediates
DK0443449T3 (da) Fremgangsmåde til fremstilling af oxetanoner
IL172692A0 (en) Method for dehydrating substituted 4-dimethylamino-2-aryl-butan-2-ol compounds and method for producing substituted dimethyl-(3-aryl-butyl)-amine compounds by means of heterogeneous catalysis
HK1068627A1 (en) Process for the preparation of racemic citalopram and/or s-or r-citalopram by separation of a mixture of r- and s-citalopram
IS5884A (is) Aðferð til framleiðslu á hreinu sítalóprami
WO2003043575A3 (fr) Procede de synthese de (r)-1-(3,5-bis(trifluoromethyl)-phenyl)ethan-1-ol et de certains de ses esters par resolution cinetique dynamique
BG105348A (en) PROCESS FOR OBTAINING HMG-CoA REDUCTASE INHIBITORS OF HIGH PURITY
IS2167B (is) Aðferð til framleiðslu á sítalóprami
DK1206452T3 (da) Fremgangsmåde til fremstilling af benzoperhydro-isoindolforbindelser
DK1280752T3 (da) Fremgangsmåde til fremstilling af 2-alkyl-3-chlorphenoler
DK0934256T3 (da) Fremgangsmåde til fremstilling af cyanocinnamamider
IL149089A0 (en) Method for production of benzofuranone oximes
NO20030640D0 (no) Fremgangsmåte for fremstilling av bicykliske forbindelser og mellomprodukter derfor
AU4264799A (en) Method for stereoselective production of substituted cyclohexylcyanhydrins
DK1444244T3 (da) Fremgangsmåde til fremstilling af desclarithromycin, samt mellemprodukter
AU2003288004A1 (en) Process for the preparation of an enantiomerically enriched schiff base