ME01555B - FARMACEUTSKI PREPARAT KOJI SADRŽI {lS)-1,5-ANHIDR0-1-[5-{4-ETOKSIBENZIL)-2-METOKSI-4-METILFENIL]-1- TIO-D-GLUCITOL l METFORMIN l NJEGOVE UPOTREBE U LIJEČENJU DIJABETESA - Google Patents
FARMACEUTSKI PREPARAT KOJI SADRŽI {lS)-1,5-ANHIDR0-1-[5-{4-ETOKSIBENZIL)-2-METOKSI-4-METILFENIL]-1- TIO-D-GLUCITOL l METFORMIN l NJEGOVE UPOTREBE U LIJEČENJU DIJABETESAInfo
- Publication number
- ME01555B ME01555B MEP-2013-137A MEP13713A ME01555B ME 01555 B ME01555 B ME 01555B ME P13713 A MEP13713 A ME P13713A ME 01555 B ME01555 B ME 01555B
- Authority
- ME
- Montenegro
- Prior art keywords
- ethoxybenzyl
- glucitol
- metformin
- thio
- methylphenyl
- Prior art date
Links
- 206010012601 diabetes mellitus Diseases 0.000 title abstract 3
- XZWYZXLIPXDOLR-UHFFFAOYSA-N metformin Chemical compound CN(C)C(=N)NC(N)=N XZWYZXLIPXDOLR-UHFFFAOYSA-N 0.000 title abstract 2
- 229960003105 metformin Drugs 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 208000002249 Diabetes Complications Diseases 0.000 abstract 1
- WHSOLWOTCHFFBK-ZQGJOIPISA-N Luseogliflozin Chemical compound C1=CC(OCC)=CC=C1CC1=CC([C@H]2[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)S2)O)=C(OC)C=C1C WHSOLWOTCHFFBK-ZQGJOIPISA-N 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
- A61K31/382—Heterocyclic compounds having sulfur as a ring hetero atom having six-membered rings, e.g. thioxanthenes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/133—Amines having hydroxy groups, e.g. sphingosine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/64—Sulfonylureas, e.g. glibenclamide, tolbutamide, chlorpropamide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7008—Compounds having an amino group directly attached to a carbon atom of the saccharide radical, e.g. D-galactosamine, ranimustine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
- A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
- A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D335/00—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom
- C07D335/02—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Diabetes (AREA)
- Molecular Biology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Urology & Nephrology (AREA)
- Endocrinology (AREA)
- Obesity (AREA)
- Vascular Medicine (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Ophthalmology & Optometry (AREA)
- Emergency Medicine (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Predmetni pronalazak se odnosi na farmaceutske preparate koji su korisni u lečenju dijabetes melitusa, bolesti koje se dovode u vezu sa dijabetesom melitusom ili komplikacija dijabetesa melitusa, i to na farmaceutske preparate koji sadrže kombinaciju (A) (1S)-1,5-anhidro-1-[5-(4-etoksibenzil)-2-metoksi-4-metilfenil]-1-tio-D-glucitola ili njegove farmaceutski prihvatljive soli ili hidrata takvog jedinjenja ili soli; i (B) metformina.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2009100210 | 2009-04-16 | ||
PCT/JP2010/057196 WO2010119990A1 (en) | 2009-04-16 | 2010-04-16 | Pharmaceutical compositions |
EP10764570.7A EP2419097B1 (en) | 2009-04-16 | 2010-04-16 | Pharmaceutical composition comprising (1s)-1,5-anhydro-1-[5-(4-ethoxybenzyl)-2-methoxy-4-methylphenyl]-1-thio-d-glucitol and metformin and uses thereof in the treatment of diabetes |
Publications (1)
Publication Number | Publication Date |
---|---|
ME01555B true ME01555B (me) | 2014-04-20 |
Family
ID=42982643
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MEP-2013-137A ME01555B (me) | 2009-04-16 | 2010-04-16 | FARMACEUTSKI PREPARAT KOJI SADRŽI {lS)-1,5-ANHIDR0-1-[5-{4-ETOKSIBENZIL)-2-METOKSI-4-METILFENIL]-1- TIO-D-GLUCITOL l METFORMIN l NJEGOVE UPOTREBE U LIJEČENJU DIJABETESA |
MEP-2015-6A ME02015B (me) | 2009-04-16 | 2010-04-16 | Farmaceutski preparati sa (1S)-1,5-anhidro-1-[5-(4-etoksibenzil)-2-metoksi- 4-metilfenil]-1-tio-D-glucitolom i sekretagogom insulina |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MEP-2015-6A ME02015B (me) | 2009-04-16 | 2010-04-16 | Farmaceutski preparati sa (1S)-1,5-anhidro-1-[5-(4-etoksibenzil)-2-metoksi- 4-metilfenil]-1-tio-D-glucitolom i sekretagogom insulina |
Country Status (30)
Country | Link |
---|---|
US (1) | US20120040898A1 (me) |
EP (3) | EP2829271A3 (me) |
JP (4) | JP5077786B2 (me) |
KR (2) | KR20120016051A (me) |
CN (7) | CN105343880A (me) |
AR (1) | AR076317A1 (me) |
AU (1) | AU2010237748B2 (me) |
BR (1) | BRPI1012539A2 (me) |
CA (1) | CA2755392A1 (me) |
CY (2) | CY1114703T1 (me) |
DK (2) | DK2601949T3 (me) |
ES (2) | ES2431300T3 (me) |
HK (6) | HK1217301A1 (me) |
HR (2) | HRP20131120T1 (me) |
ME (2) | ME01555B (me) |
MX (1) | MX2011010901A (me) |
MY (3) | MY182720A (me) |
NZ (4) | NZ623838A (me) |
PH (3) | PH12015500235A1 (me) |
PL (2) | PL2601949T3 (me) |
PT (2) | PT2601949E (me) |
RS (2) | RS53056B (me) |
RU (2) | RU2532330C2 (me) |
SG (6) | SG2014012405A (me) |
SI (2) | SI2419097T1 (me) |
SM (1) | SMT201500015B (me) |
TW (3) | TW201500043A (me) |
UA (2) | UA105216C2 (me) |
WO (1) | WO2010119990A1 (me) |
ZA (1) | ZA201106727B (me) |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7772191B2 (en) | 2005-05-10 | 2010-08-10 | Boehringer Ingelheim International Gmbh | Processes for preparing of glucopyranosyl-substituted benzyl-benzene derivatives and intermediates therein |
WO2011039108A2 (en) | 2009-09-30 | 2011-04-07 | Boehringer Ingelheim International Gmbh | Processes for preparing of glucopyranosyl-substituted benzyl-benzene derivatives |
US10610489B2 (en) | 2009-10-02 | 2020-04-07 | Boehringer Ingelheim International Gmbh | Pharmaceutical composition, pharmaceutical dosage form, process for their preparation, methods for treating and uses thereof |
US20120283169A1 (en) * | 2010-11-08 | 2012-11-08 | Boehringer Ingelheim International Gmbh | Pharmaceutical composition, methods for treating and uses thereof |
TR201101809A1 (tr) * | 2010-12-21 | 2012-07-23 | Sanovel İlaç Sanayi̇ Ve Ti̇caret Anoni̇m Şi̇rketi̇ | Vildagliptin ve glimepirid kombinasyonları. |
US9192617B2 (en) | 2012-03-20 | 2015-11-24 | Boehringer Ingelheim International Gmbh | Pharmaceutical composition, methods for treating and uses thereof |
JP6234443B2 (ja) | 2012-05-17 | 2017-11-22 | ブイティーブイ・セラピューティクス・エルエルシー | 糖尿病治療のためのグルコキナーゼ活性化因子組成物 |
EP2891499A4 (en) * | 2012-08-30 | 2016-02-24 | Taisho Pharmaceutical Co Ltd | ASSOCIATION OF A SGLT2 INHIBITOR AND AN ANTIHYPERTENSEUR |
US11813275B2 (en) | 2013-04-05 | 2023-11-14 | Boehringer Ingelheim International Gmbh | Pharmaceutical composition, methods for treating and uses thereof |
US20140303097A1 (en) | 2013-04-05 | 2014-10-09 | Boehringer Ingelheim International Gmbh | Pharmaceutical composition, methods for treating and uses thereof |
US20140303098A1 (en) | 2013-04-05 | 2014-10-09 | Boehringer Ingelheim International Gmbh | Pharmaceutical composition, methods for treating and uses thereof |
AU2014255727B2 (en) | 2013-04-18 | 2019-07-25 | Boehringer Ingelheim International Gmbh | Pharmaceutical composition, methods for treating and uses thereof |
TW201513857A (zh) * | 2013-07-05 | 2015-04-16 | Cadila Healthcare Ltd | 協同性組成物 |
ES2869463T3 (es) * | 2015-02-27 | 2021-10-25 | Asan Found | Composición para la prevención o tratamiento de la calcificación de válvulas que contiene un inhibidor de DPP-4 |
CN105963280B (zh) * | 2016-06-30 | 2018-11-06 | 合肥华方医药科技有限公司 | 一种伏格列波糖口腔速溶膜及其制备方法 |
KR20190070956A (ko) | 2016-10-19 | 2019-06-21 | 베링거 인겔하임 인터내셔날 게엠베하 | Ssao/vap-1 억제제 및 sglt2 억제제를 포함하는 복합제제 및 이의 용도 |
EP3540072A4 (en) * | 2016-11-14 | 2020-05-20 | Kaohsiung Medical University | METHOD FOR DETERMINING IF GLUCOSE METABOLISM IS ABNORMAL, AND PREVENTION AND TREATMENT THEREOF |
WO2019201752A1 (en) | 2018-04-17 | 2019-10-24 | Boehringer Ingelheim International Gmbh | Pharmaceutical composition, methods for treating and uses thereof |
KR20190137343A (ko) | 2018-06-01 | 2019-12-11 | 김유찬 | 계량 인덕션 |
MX2020008905A (es) | 2018-06-12 | 2020-12-03 | Vtv Therapeutics Llc | Usos terapeuticos de activadores de glucoquinasa en combinacion con insulina o analogos de insulinas. |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE4432757A1 (de) | 1994-09-14 | 1996-03-21 | Boehringer Mannheim Gmbh | Pharmazeutische Zubereitung enthaltend Metformin und Verfahren zu deren Herstellung |
JP2003520759A (ja) | 1999-08-31 | 2003-07-08 | アンドルックス ファーマスーティカルズ インコーポレーテッド | 単位核を有する徐放性錠剤 |
CN100577175C (zh) * | 2001-04-04 | 2010-01-06 | 奥索-麦克尼尔药品公司 | 包括葡萄糖重吸收抑制剂和ppar调节剂的联合疗法 |
ES2258141T3 (es) * | 2001-04-11 | 2006-08-16 | Bristol-Myers Squibb Company | Complejos de aminoacidos de glucosidos c-arilo para el tratamiento de la diabetes y procedimiento. |
TW200637839A (en) * | 2005-01-07 | 2006-11-01 | Taisho Pharmaceutical Co Ltd | 1-thio-d-glucitol derivatives |
CN101479254B (zh) * | 2006-06-29 | 2012-05-30 | 大正制药株式会社 | C-苯基1-硫代山梨醇化合物 |
JP5194588B2 (ja) * | 2006-07-06 | 2013-05-08 | 大正製薬株式会社 | 1−チオ−d−グルシトール誘導体を有効成分として含有する糖尿病の予防又は治療剤 |
US8039441B2 (en) * | 2006-08-15 | 2011-10-18 | Boehringer Ingelheim International Gmbh | Glucopyranosyl-substituted cyclopropylbenzene derivatives, pharmaceutical compositions containing such compounds, their use as SGLT inhibitors and process for their manufacture |
US20100298243A1 (en) * | 2006-11-09 | 2010-11-25 | Boehringer Ingelheim International Gmbh | Combination therapy with sglt-2 inhibitors and their pharmaceutical compositions |
WO2008072726A1 (ja) * | 2006-12-14 | 2008-06-19 | Taisho Pharmaceutical Co., Ltd. | 1-フェニル 1-チオ-d-グルシト-ル誘導体 |
PE20090603A1 (es) | 2007-08-16 | 2009-06-11 | Boehringer Ingelheim Int | Composicion farmaceutica que comprende un inhibidor de sglt2 y un inhibidor de dpp iv |
PE20090938A1 (es) | 2007-08-16 | 2009-08-08 | Boehringer Ingelheim Int | Composicion farmaceutica que comprende un derivado de benceno sustituido con glucopiranosilo |
-
2010
- 2010-04-16 MY MYPI2015001283A patent/MY182720A/en unknown
- 2010-04-16 CA CA2755392A patent/CA2755392A1/en not_active Abandoned
- 2010-04-16 UA UAA201113444A patent/UA105216C2/ru unknown
- 2010-04-16 ES ES10764570T patent/ES2431300T3/es active Active
- 2010-04-16 SG SG2014012405A patent/SG2014012405A/en unknown
- 2010-04-16 US US13/264,687 patent/US20120040898A1/en not_active Abandoned
- 2010-04-16 SG SG2014014807A patent/SG2014014807A/en unknown
- 2010-04-16 CN CN201510876739.3A patent/CN105343880A/zh active Pending
- 2010-04-16 CN CN201510876678.0A patent/CN105477639A/zh active Pending
- 2010-04-16 PL PL13157571T patent/PL2601949T3/pl unknown
- 2010-04-16 AU AU2010237748A patent/AU2010237748B2/en not_active Ceased
- 2010-04-16 RS RS20130508A patent/RS53056B/en unknown
- 2010-04-16 CN CN201510876753.3A patent/CN105434430A/zh active Pending
- 2010-04-16 WO PCT/JP2010/057196 patent/WO2010119990A1/en active Application Filing
- 2010-04-16 NZ NZ623838A patent/NZ623838A/en not_active IP Right Cessation
- 2010-04-16 ES ES13157571.4T patent/ES2523408T3/es active Active
- 2010-04-16 JP JP2011540651A patent/JP5077786B2/ja active Active
- 2010-04-16 CN CN2010800169522A patent/CN102395364A/zh active Pending
- 2010-04-16 PT PT131575714T patent/PT2601949E/pt unknown
- 2010-04-16 BR BRPI1012539A patent/BRPI1012539A2/pt not_active IP Right Cessation
- 2010-04-16 DK DK13157571.4T patent/DK2601949T3/da active
- 2010-04-16 NZ NZ606888A patent/NZ606888A/en not_active IP Right Cessation
- 2010-04-16 DK DK10764570.7T patent/DK2419097T3/da active
- 2010-04-16 ME MEP-2013-137A patent/ME01555B/me unknown
- 2010-04-16 MX MX2011010901A patent/MX2011010901A/es active IP Right Grant
- 2010-04-16 UA UAA201314870A patent/UA111742C2/uk unknown
- 2010-04-16 AR ARP100101273A patent/AR076317A1/es unknown
- 2010-04-16 PL PL10764570T patent/PL2419097T3/pl unknown
- 2010-04-16 ME MEP-2015-6A patent/ME02015B/me unknown
- 2010-04-16 TW TW103133246A patent/TW201500043A/zh unknown
- 2010-04-16 CN CN201510876708.8A patent/CN105343060A/zh active Pending
- 2010-04-16 EP EP14183168.5A patent/EP2829271A3/en not_active Withdrawn
- 2010-04-16 CN CN201510876712.4A patent/CN105343871A/zh active Pending
- 2010-04-16 NZ NZ595314A patent/NZ595314A/xx unknown
- 2010-04-16 EP EP10764570.7A patent/EP2419097B1/en active Active
- 2010-04-16 SG SG2014012553A patent/SG2014012553A/en unknown
- 2010-04-16 CN CN201510876636.7A patent/CN105343059A/zh active Pending
- 2010-04-16 MY MYPI2015001281A patent/MY183793A/en unknown
- 2010-04-16 TW TW105105937A patent/TW201622720A/zh unknown
- 2010-04-16 SI SI201030365T patent/SI2419097T1/sl unknown
- 2010-04-16 SI SI201030784T patent/SI2601949T1/sl unknown
- 2010-04-16 SG SG2011073848A patent/SG175154A1/en unknown
- 2010-04-16 SG SG2014015093A patent/SG2014015093A/en unknown
- 2010-04-16 MY MYPI2011004937A patent/MY156679A/en unknown
- 2010-04-16 KR KR1020117023612A patent/KR20120016051A/ko not_active Application Discontinuation
- 2010-04-16 TW TW099111992A patent/TW201103534A/zh unknown
- 2010-04-16 RU RU2011146335/15A patent/RU2532330C2/ru not_active IP Right Cessation
- 2010-04-16 EP EP13157571.4A patent/EP2601949B1/en active Active
- 2010-04-16 RS RS20150042A patent/RS53761B1/en unknown
- 2010-04-16 PT PT107645707T patent/PT2419097E/pt unknown
- 2010-04-16 NZ NZ710575A patent/NZ710575A/en not_active IP Right Cessation
- 2010-04-16 KR KR1020157009538A patent/KR20150046382A/ko not_active Application Discontinuation
- 2010-04-16 SG SG2014012462A patent/SG2014012462A/en unknown
-
2011
- 2011-09-14 ZA ZA2011/06727A patent/ZA201106727B/en unknown
-
2012
- 2012-08-31 JP JP2012191753A patent/JP5660094B2/ja not_active Expired - Fee Related
-
2013
- 2013-11-25 HR HRP20131120AT patent/HRP20131120T1/hr unknown
- 2013-12-05 CY CY20131101103T patent/CY1114703T1/el unknown
-
2014
- 2014-05-26 RU RU2014121260/15A patent/RU2014121260A/ru not_active Application Discontinuation
- 2014-11-05 HR HRP20141080AT patent/HRP20141080T1/hr unknown
- 2014-12-03 JP JP2014245257A patent/JP5910711B2/ja active Active
-
2015
- 2015-01-16 CY CY20151100045T patent/CY1115907T1/el unknown
- 2015-01-19 SM SM201500015T patent/SMT201500015B/xx unknown
- 2015-02-03 PH PH12015500235A patent/PH12015500235A1/en unknown
- 2015-12-25 JP JP2015253932A patent/JP6066144B2/ja active Active
-
2016
- 2016-05-11 HK HK16105348.0A patent/HK1217301A1/zh unknown
- 2016-05-11 HK HK16105353.2A patent/HK1217302A1/zh unknown
- 2016-05-12 HK HK16105415.8A patent/HK1217434A1/zh unknown
- 2016-05-12 HK HK16105417.6A patent/HK1217435A1/zh unknown
- 2016-06-16 HK HK16106920.4A patent/HK1218871A1/zh unknown
- 2016-06-17 HK HK16106970.3A patent/HK1218881A1/zh unknown
-
2019
- 2019-04-30 PH PH12019500961A patent/PH12019500961B1/en unknown
- 2019-04-30 PH PH12019500959A patent/PH12019500959B1/en unknown
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ME01555B (me) | FARMACEUTSKI PREPARAT KOJI SADRŽI {lS)-1,5-ANHIDR0-1-[5-{4-ETOKSIBENZIL)-2-METOKSI-4-METILFENIL]-1- TIO-D-GLUCITOL l METFORMIN l NJEGOVE UPOTREBE U LIJEČENJU DIJABETESA | |
AR112074A2 (es) | Derivados de 2-carboxamida-cicloamino-urea como inhibidores de pi-3 | |
WO2007122580A3 (en) | Compositions of phenylephrine useful for treatment of respiratory illness | |
BRPI0517701A8 (pt) | métodos de tratamento de diabetes mellitus | |
CL2007002610A1 (es) | Compuestos derivados de bipiridina sustituida; procedimiento de preparacion; composicion farmaceutica; y uso en el tratamiento y/o la profilaxis de enfermedades tales como hipertonia, diabetes, infarto de miocardio, entre otras. | |
CL2008000592A1 (es) | Compuestos derivados de pirrol sustituido, supresores de la secrecion de acidos; composicion farmaceutica; y uso en el tratamiento o profilaxis en enfermedades tales como ulcera peptica, gastritis, esofagitis, entre otras. | |
EA201200968A1 (ru) | Применение транс-кломифена для предотвращения или лечения диабета 2 типа у мужчин | |
WO2007107470A3 (en) | Pyrazoles as 11-beta-hsd-1 | |
UY30819A1 (es) | Derivados de pirazol, composiciones farmacéuticas conteniéndolos, procesos de preparacion y aplicaciones | |
CL2007003686A1 (es) | Compuestos derivados de indol con anillo unido en las posiciones 4,5; composicion farmaceutica que comprende a dicho compuesto; y uso del compuesto para tratar una infeccion viral. | |
NO20084924L (no) | N-(2-thiazolyl)-amid derivater som GSK-3 inhibitorer | |
NO20074824L (no) | Forlengelse av tid til sykdomsprogresjon eller overlevelse hos kreftpasienter | |
CL2013001104A1 (es) | Composicion farmaceutica que comprende un inhibidor de sglt2 y una insulina; y uso para tratar una enfermedad o afeccion tal como diabetes mellitus, diabetes mellitus tipo 1 y 2, entre otras. | |
GT201200164A (es) | "nuevos compuestos de espiropiperidina" | |
TW200633992A (en) | Biaryloxymethylarenecarboxylic acids | |
WO2006072458A3 (de) | Substituierte oxindol-derivate, diese enthaltende arzneimittel und deren verwendung | |
EA201201623A1 (ru) | Лечение диабета 2 типа | |
CO6270306A2 (es) | Compuesto inhibidor de glicogeno fosforilasa y composicion farmaceutica del mismo | |
WO2007130825A3 (en) | Fused heterocyclic compounds and their use as mglur5 modulators | |
EA201190320A1 (ru) | Гетероциклические сульфонамиды, их применения и фармацевтические композиции | |
DE602007014206D1 (de) | Neuartige serotonin-wiederaufnahmehemmer als arzneimittel mit peripheriesystem-beschränkter aktivität | |
CL2007001752A1 (es) | Compuesto 4-[5(2-amino-etansulfonil)-isoquinolin-7-il]-fenolo una sal farmaceuticamente aceptable o un hidrato o la sal del mismo;composicion farmaceutica que comprende a dicho compuesto,composicion farmaceutica liofilizada;y uso del compuesto como antineiplasico y/o antiviral. | |
WO2008098985A3 (en) | Pharmaceutical composition for the treatment of il-8 mediated diseases | |
NO20074536L (no) | Anvendelse av jern (III)-komplekssammensetninger | |
EA201000392A1 (ru) | Соединение, представляющее собой ингибитор гликогенфосфорилазы, и его фармацевтическая композиция |