MD522G2 - Noi derivaţi de piperidinii tioindol, procedeu de preparare a lor, compoziţii farmaceutice care le conţin, utilizare a lor ca analgezice - Google Patents
Noi derivaţi de piperidinii tioindol, procedeu de preparare a lor, compoziţii farmaceutice care le conţin, utilizare a lor ca analgeziceInfo
- Publication number
- MD522G2 MD522G2 MD95-0083A MD950083A MD522G2 MD 522 G2 MD522 G2 MD 522G2 MD 950083 A MD950083 A MD 950083A MD 522 G2 MD522 G2 MD 522G2
- Authority
- MD
- Moldova
- Prior art keywords
- thioindol
- preparation
- new
- pharmaceutical compositions
- analgetics
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Abstract
Prezenta invenţie se referă la derivaţii cu formula:precum şi la sărurile sale aditive şi utilizarea lor în terapeutică ca medicamente cu proprietăţi analgezice.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9305966A FR2705346B1 (fr) | 1993-05-18 | 1993-05-18 | Nouveaux dérivés de pipéridinyl thio indole, leurs procédés de préparation, compositions pharmaceutiques les contenant, utiles notamment comme antalgiques . |
PCT/FR1994/000410 WO1994026736A1 (fr) | 1993-05-18 | 1994-04-13 | Derives de piperidinyl thio indole comme antalgiques |
Publications (2)
Publication Number | Publication Date |
---|---|
MD522F1 MD522F1 (ro) | 1996-04-30 |
MD522G2 true MD522G2 (ro) | 1997-01-31 |
Family
ID=9447241
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MD95-0083A MD522G2 (ro) | 1993-05-18 | 1994-12-30 | Noi derivaţi de piperidinii tioindol, procedeu de preparare a lor, compoziţii farmaceutice care le conţin, utilizare a lor ca analgezice |
Country Status (15)
Country | Link |
---|---|
US (1) | US5317025A (ro) |
EP (1) | EP0699195A1 (ro) |
JP (1) | JPH09500611A (ro) |
CN (1) | CN1124026A (ro) |
AU (1) | AU6571594A (ro) |
CA (1) | CA2161021A1 (ro) |
CZ (1) | CZ304195A3 (ro) |
EE (1) | EE9400296A (ro) |
FI (1) | FI954931A (ro) |
FR (1) | FR2705346B1 (ro) |
HU (1) | HUT74866A (ro) |
MD (1) | MD522G2 (ro) |
NZ (1) | NZ265304A (ro) |
TW (1) | TW257756B (ro) |
WO (1) | WO1994026736A1 (ro) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DK139593D0 (da) * | 1993-12-16 | 1993-12-16 | Lundbeck & Co As H | Compounds |
JPH10503501A (ja) * | 1994-08-03 | 1998-03-31 | アスタ メディカ アクチエンゲゼルシャフト | 抗喘息、抗アレルギー、抗炎症及び免疫修飾作用を有するインドール、インダゾール、ピリドピロール及びピリドピラゾール誘導体 |
US5521196A (en) * | 1994-10-05 | 1996-05-28 | Eli Lilly And Company | 5-HT1F agonists for the treatment of migraine |
KR19980703048A (ko) * | 1995-03-20 | 1998-09-05 | 피터쥐.스트링거 | 5-치환-3-(1,2,3,6-테트라히드로피리딘-4-일)- 및 3-(피페리딘-4-일)-1h-인돌: 신규한 5-ht1f 아고니스트 |
TWI328009B (en) | 2003-05-21 | 2010-08-01 | Glaxo Group Ltd | Quinoline derivatives as phosphodiesterase inhibitors |
CA2591922A1 (en) * | 2004-12-24 | 2006-06-29 | Prosidion Limited | G-protein coupled receptor (gpr116) agonists and use thereof for treating obesity and diabetes |
BRPI0613505A2 (pt) * | 2005-06-30 | 2011-01-11 | Prosidion Ltd | agonistas de gpcr |
PE20081659A1 (es) * | 2007-01-04 | 2008-10-24 | Prosidion Ltd | Agonistas de gpcr |
AR064736A1 (es) * | 2007-01-04 | 2009-04-22 | Prosidion Ltd | Agonistas de gpcr |
JP2013525490A (ja) * | 2010-05-06 | 2013-06-20 | メルク・シャープ・エンド・ドーム・コーポレイション | Faahのモジュレータとして有用なアザインドール誘導体 |
RU2766579C2 (ru) | 2015-07-02 | 2022-03-15 | ХОРАЙЗОН ОРФАН ЭлЭлСи | Цистеаминдиоксигеназа-резистентные аналоги цистеамина и их применение |
CN104945305A (zh) * | 2015-07-03 | 2015-09-30 | 北京石油化工学院 | 一种实现吲哚类化合物选择性芳巯基化的方法 |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB925429A (en) * | 1960-04-01 | 1963-05-08 | Irwin Neisler & Co | Indole derivatives |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3264311A (en) * | 1963-05-02 | 1966-08-02 | Upjohn Co | Esters of 3-(aminosulfinyl) indole-2-carboxylic acids |
-
1993
- 1993-05-18 FR FR9305966A patent/FR2705346B1/fr not_active Expired - Fee Related
- 1993-06-25 US US08/081,704 patent/US5317025A/en not_active Expired - Fee Related
-
1994
- 1994-04-13 CA CA002161021A patent/CA2161021A1/en not_active Abandoned
- 1994-04-13 HU HU9503281A patent/HUT74866A/hu unknown
- 1994-04-13 JP JP6525034A patent/JPH09500611A/ja active Pending
- 1994-04-13 CZ CZ953041A patent/CZ304195A3/cs unknown
- 1994-04-13 EP EP94913639A patent/EP0699195A1/fr not_active Withdrawn
- 1994-04-13 AU AU65715/94A patent/AU6571594A/en not_active Abandoned
- 1994-04-13 NZ NZ265304A patent/NZ265304A/en unknown
- 1994-04-13 WO PCT/FR1994/000410 patent/WO1994026736A1/fr not_active Application Discontinuation
- 1994-04-13 CN CN94192149A patent/CN1124026A/zh active Pending
- 1994-04-20 TW TW083103517A patent/TW257756B/zh active
- 1994-11-23 EE EE9400296A patent/EE9400296A/xx unknown
- 1994-12-30 MD MD95-0083A patent/MD522G2/ro active IP Right Grant
-
1995
- 1995-10-17 FI FI954931A patent/FI954931A/fi not_active Application Discontinuation
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB925429A (en) * | 1960-04-01 | 1963-05-08 | Irwin Neisler & Co | Indole derivatives |
Also Published As
Publication number | Publication date |
---|---|
EP0699195A1 (fr) | 1996-03-06 |
FR2705346B1 (fr) | 1995-08-11 |
FR2705346A1 (fr) | 1994-11-25 |
MD522F1 (ro) | 1996-04-30 |
CA2161021A1 (en) | 1994-11-24 |
CN1124026A (zh) | 1996-06-05 |
WO1994026736A1 (fr) | 1994-11-24 |
US5317025A (en) | 1994-05-31 |
HU9503281D0 (en) | 1996-01-29 |
TW257756B (ro) | 1995-09-21 |
FI954931A0 (fi) | 1995-10-17 |
AU6571594A (en) | 1994-12-12 |
NZ265304A (en) | 1997-02-24 |
CZ304195A3 (en) | 1996-03-13 |
FI954931A (fi) | 1995-11-20 |
JPH09500611A (ja) | 1997-01-21 |
HUT74866A (en) | 1997-02-28 |
EE9400296A (et) | 1996-04-15 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG3A | Granted patent for invention | ||
IF99 | Valid patent on 19990615 |
Free format text: EXPIRES: 20141230 |