MD522F1 - Noi derivati de piperidinil tioindol, procedeu de preparare a lor, compozitii farmaceutice care le contin, utilizare a lor ca analgezice - Google Patents
Noi derivati de piperidinil tioindol, procedeu de preparare a lor, compozitii farmaceutice care le contin, utilizare a lor ca analgeziceInfo
- Publication number
- MD522F1 MD522F1 MD95-0083A MD950083A MD522F1 MD 522 F1 MD522 F1 MD 522F1 MD 950083 A MD950083 A MD 950083A MD 522 F1 MD522 F1 MD 522F1
- Authority
- MD
- Moldova
- Prior art keywords
- thyoindol
- analgetics
- derivatives
- preparation
- pharmaceutical compositions
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Pain & Pain Management (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9305966A FR2705346B1 (fr) | 1993-05-18 | 1993-05-18 | Nouveaux dérivés de pipéridinyl thio indole, leurs procédés de préparation, compositions pharmaceutiques les contenant, utiles notamment comme antalgiques . |
| PCT/FR1994/000410 WO1994026736A1 (fr) | 1993-05-18 | 1994-04-13 | Derives de piperidinyl thio indole comme antalgiques |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MD522F1 true MD522F1 (ro) | 1996-04-30 |
| MD522G2 MD522G2 (ro) | 1997-01-31 |
Family
ID=9447241
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MD95-0083A MD522G2 (ro) | 1993-05-18 | 1994-12-30 | Noi derivaţi de piperidinii tioindol, procedeu de preparare a lor, compoziţii farmaceutice care le conţin, utilizare a lor ca analgezice |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US5317025A (ro) |
| EP (1) | EP0699195A1 (ro) |
| JP (1) | JPH09500611A (ro) |
| CN (1) | CN1124026A (ro) |
| AU (1) | AU6571594A (ro) |
| CA (1) | CA2161021A1 (ro) |
| CZ (1) | CZ304195A3 (ro) |
| EE (1) | EE9400296A (ro) |
| FI (1) | FI954931A (ro) |
| FR (1) | FR2705346B1 (ro) |
| HU (1) | HUT74866A (ro) |
| MD (1) | MD522G2 (ro) |
| NZ (1) | NZ265304A (ro) |
| TW (1) | TW257756B (ro) |
| WO (1) | WO1994026736A1 (ro) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK139593D0 (da) * | 1993-12-16 | 1993-12-16 | Lundbeck & Co As H | Compounds |
| EP0775131A2 (de) * | 1994-08-03 | 1997-05-28 | ASTA Medica Aktiengesellschaft | Indol-, indazol-, pyridopyrrol- und pyridopyrazol-derivate mit antiasthmatischer, antiallergischer, entzündungshemmender und immunmodulierender wirkung |
| US5521196A (en) * | 1994-10-05 | 1996-05-28 | Eli Lilly And Company | 5-HT1F agonists for the treatment of migraine |
| AU702322B2 (en) * | 1995-03-20 | 1999-02-18 | Eli Lilly And Company | 5-substituted-3-(1,2,3,6-tetrahydropyridin-4-yl)- and 3-(piperidin-4-yl)-1h-indoles: new 5-ht1f agonists |
| TWI328009B (en) | 2003-05-21 | 2010-08-01 | Glaxo Group Ltd | Quinoline derivatives as phosphodiesterase inhibitors |
| CA2591922A1 (en) * | 2004-12-24 | 2006-06-29 | Prosidion Limited | G-protein coupled receptor (gpr116) agonists and use thereof for treating obesity and diabetes |
| CA2613235A1 (en) * | 2005-06-30 | 2007-01-11 | Prosidion Limited | Gpcr agonists |
| CL2008000017A1 (es) * | 2007-01-04 | 2008-08-01 | Prosidion Ltd | Compuestos derivados de heterociclos de nitrogeno y oxigeno, agonistas de gpcr; composicion farmaceutica que comprende a dicho compuesto; y uso del compuesto para el tratamiento de la obesidad, diabetes, sindrome metabolico, hiperlipidemia, toleranci |
| CL2008000018A1 (es) * | 2007-01-04 | 2008-08-01 | Prosidion Ltd | Compuestos derivados de heterociclos de nitrogeno y oxigeno, agonistas de gpcr; composicion farmaceutica que comprende a dicho compuesto; y uso del compuesto para el tratamiento de la obesidad, diabetes, sindrome metabolico, hiperlipidemia, toleranci |
| CA2797281A1 (en) * | 2010-05-06 | 2011-11-10 | Merck Sharp & Dohme Corp. | Aza-indole derivatives useful as modulators of faah |
| JP2018525350A (ja) | 2015-07-02 | 2018-09-06 | ホライズン オルファン エルエルシー | Ａｄｏ耐性システアミン類似体およびその使用 |
| CN104945305A (zh) * | 2015-07-03 | 2015-09-30 | 北京石油化工学院 | 一种实现吲哚类化合物选择性芳巯基化的方法 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB925429A (en) * | 1960-04-01 | 1963-05-08 | Irwin Neisler & Co | Indole derivatives |
| US3264311A (en) * | 1963-05-02 | 1966-08-02 | Upjohn Co | Esters of 3-(aminosulfinyl) indole-2-carboxylic acids |
-
1993
- 1993-05-18 FR FR9305966A patent/FR2705346B1/fr not_active Expired - Fee Related
- 1993-06-25 US US08/081,704 patent/US5317025A/en not_active Expired - Fee Related
-
1994
- 1994-04-13 CN CN94192149A patent/CN1124026A/zh active Pending
- 1994-04-13 NZ NZ265304A patent/NZ265304A/en unknown
- 1994-04-13 WO PCT/FR1994/000410 patent/WO1994026736A1/fr not_active Application Discontinuation
- 1994-04-13 CZ CZ953041A patent/CZ304195A3/cs unknown
- 1994-04-13 JP JP6525034A patent/JPH09500611A/ja active Pending
- 1994-04-13 AU AU65715/94A patent/AU6571594A/en not_active Abandoned
- 1994-04-13 HU HU9503281A patent/HUT74866A/hu unknown
- 1994-04-13 EP EP94913639A patent/EP0699195A1/fr not_active Withdrawn
- 1994-04-13 CA CA002161021A patent/CA2161021A1/en not_active Abandoned
- 1994-04-20 TW TW083103517A patent/TW257756B/zh active
- 1994-11-23 EE EE9400296A patent/EE9400296A/xx unknown
- 1994-12-30 MD MD95-0083A patent/MD522G2/ro active IP Right Grant
-
1995
- 1995-10-17 FI FI954931A patent/FI954931A/fi not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| NZ265304A (en) | 1997-02-24 |
| WO1994026736A1 (fr) | 1994-11-24 |
| MD522G2 (ro) | 1997-01-31 |
| JPH09500611A (ja) | 1997-01-21 |
| FI954931A0 (fi) | 1995-10-17 |
| FR2705346A1 (fr) | 1994-11-25 |
| CN1124026A (zh) | 1996-06-05 |
| FI954931A (fi) | 1995-11-20 |
| FR2705346B1 (fr) | 1995-08-11 |
| HU9503281D0 (en) | 1996-01-29 |
| EP0699195A1 (fr) | 1996-03-06 |
| AU6571594A (en) | 1994-12-12 |
| CZ304195A3 (en) | 1996-03-13 |
| TW257756B (ro) | 1995-09-21 |
| EE9400296A (et) | 1996-04-15 |
| US5317025A (en) | 1994-05-31 |
| CA2161021A1 (en) | 1994-11-24 |
| HUT74866A (en) | 1997-02-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG3A | Granted patent for invention | ||
| IF99 | Valid patent on 19990615 |
Free format text: EXPIRES: 20141230 |