MD20120127A2 - Recombinant Koi herpesvirus (KHV), method for its production and vaccine for the prevention of a disease caused by KHV - Google Patents
Recombinant Koi herpesvirus (KHV), method for its production and vaccine for the prevention of a disease caused by KHVInfo
- Publication number
- MD20120127A2 MD20120127A2 MDA20120127A MD20120127A MD20120127A2 MD 20120127 A2 MD20120127 A2 MD 20120127A2 MD A20120127 A MDA20120127 A MD A20120127A MD 20120127 A MD20120127 A MD 20120127A MD 20120127 A2 MD20120127 A2 MD 20120127A2
- Authority
- MD
- Moldova
- Prior art keywords
- khv
- prevention
- production
- vaccine
- koi herpesvirus
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/245—Herpetoviridae, e.g. herpes simplex virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5254—Virus avirulent or attenuated
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5256—Virus expressing foreign proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
- A61K2039/552—Veterinary vaccine
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/16011—Herpesviridae
- C12N2710/16021—Viruses as such, e.g. new isolates, mutants or their genomic sequences
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/16011—Herpesviridae
- C12N2710/16022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/16011—Herpesviridae
- C12N2710/16034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/16011—Herpesviridae
- C12N2710/16041—Use of virus, viral particle or viral elements as a vector
- C12N2710/16043—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/16011—Herpesviridae
- C12N2710/16051—Methods of production or purification of viral material
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/16011—Herpesviridae
- C12N2710/16061—Methods of inactivation or attenuation
- C12N2710/16062—Methods of inactivation or attenuation by genetic engineering
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2800/00—Nucleic acids vectors
- C12N2800/20—Pseudochromosomes, minichrosomosomes
- C12N2800/204—Pseudochromosomes, minichrosomosomes of bacterial origin, e.g. BAC
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Virology (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Microbiology (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biomedical Technology (AREA)
- Communicable Diseases (AREA)
- Molecular Biology (AREA)
- Oncology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Farming Of Fish And Shellfish (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP11196171 | 2011-12-30 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| MD20120127A2 true MD20120127A2 (en) | 2013-07-31 |
| MD4481B1 MD4481B1 (ro) | 2017-05-31 |
| MD4481C1 MD4481C1 (ro) | 2017-12-31 |
Family
ID=47429841
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MDA20120127A MD4481C1 (ro) | 2011-12-30 | 2012-12-27 | Herpesvirus recombinant Koi (KHV) şi vaccin pentru profilaxia bolii cauzate de KHV |
Country Status (18)
| Country | Link |
|---|---|
| US (2) | US20140348875A1 (mo) |
| EP (1) | EP2797627B1 (mo) |
| JP (3) | JP5982009B2 (mo) |
| CN (1) | CN104159609B (mo) |
| BR (1) | BR112014016117A2 (mo) |
| HU (1) | HUE053075T2 (mo) |
| IL (1) | IL232902A0 (mo) |
| IN (1) | IN2014CN04655A (mo) |
| MD (1) | MD4481C1 (mo) |
| MX (1) | MX361408B (mo) |
| PH (1) | PH12014501388A1 (mo) |
| PL (1) | PL2797627T3 (mo) |
| RS (1) | RS61261B1 (mo) |
| RU (1) | RU2662768C2 (mo) |
| SG (1) | SG11201403066TA (mo) |
| TW (1) | TWI484034B (mo) |
| UA (2) | UA114719C2 (mo) |
| WO (1) | WO2013098214A1 (mo) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2662768C2 (ru) * | 2011-12-30 | 2018-07-31 | Гесвал с.а. | Рекомбинантный герпесвирус кои (khv) и вакцина для профилактики заболевания, вызываемого khv |
| WO2017177071A1 (en) * | 2016-04-08 | 2017-10-12 | William Marsh Rice University | Improved galactose utilization |
| RU2736472C2 (ru) * | 2016-11-18 | 2020-11-17 | Общество с ограниченной ответственностью "ЭКСИФАРМ" | Химерный белок, синтетическая днк, кодирующая указанный белок, экспрессионный вектор, штамм-продуцент синтетической днк и способ получения плазмидной днк |
| CN112279897B (zh) * | 2018-11-05 | 2021-12-28 | 深圳技术大学 | 一种预防或治疗鱼类感染CyHV-2的试剂及应用 |
| EP3662929A1 (en) * | 2018-12-07 | 2020-06-10 | IDT Biologika GmbH | A recombinant koi herpesvirus (khv) and a diva vaccine for preventing and/or treating a disease caused by khv |
| CN110101854B (zh) * | 2019-05-14 | 2022-08-02 | 四川农业大学 | 一种鲤疱疹病毒ⅲ型疫苗及其制备方法 |
| CN110468111B (zh) * | 2019-08-07 | 2022-06-17 | 西北农林科技大学 | 一种展示CyHV-2膜蛋白的重组杆状病毒及其制备方法和应用 |
| CN110452926B (zh) * | 2019-08-07 | 2022-06-17 | 西北农林科技大学 | 一种展示CyHV-2膜蛋白的重组杆状病毒及其制备方法和应用 |
| CN113679832A (zh) * | 2021-05-24 | 2021-11-23 | 苏州大学 | 一种利用冷冻干燥制备杆状病毒载鲤疱疹病毒ii型dna疫苗的方法 |
| CN115960903B (zh) * | 2022-12-23 | 2023-09-08 | 中国水产科学研究院淡水渔业研究中心 | 一种抑制CyHV-2病毒增殖的反义RNA组、重组载体和纳米粒递送系统及应用 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2068989T3 (es) | 1989-02-04 | 1995-05-01 | Akzo Nobel Nv | Tocoles como adyuvante en vacunas. |
| DE19733364A1 (de) | 1997-08-01 | 1999-02-04 | Koszinowski Ulrich H Prof | Verfahren zur Klonierung eines großen Virusgenoms |
| IL153775A0 (en) * | 2003-01-01 | 2003-07-31 | Yissum Res Dev Co | Immunizing fish against viral infection |
| JP2007223913A (ja) * | 2006-02-21 | 2007-09-06 | Kyoritsu Seiyaku Kk | コイヘルペスウイルス病ワクチン |
| JP5239023B2 (ja) * | 2006-04-13 | 2013-07-17 | 国立大学法人東京海洋大学 | コイヘルペスウイルス（ｋｈｖ）病用ｄｎａワクチン |
| MD20100029A2 (ro) * | 2007-08-28 | 2010-08-31 | Льежский Университет | Herpesvirus recombinant al crapului de koi (KHV) sau Cyprinid herpesvirus 3 (CyHV-3) şi vaccin pentru prevenirea bolii cauzate de KHV/CyHV-3 la Cyprinus carpio carpio sau Cyprinus carpio koi |
| DE102007041332A1 (de) * | 2007-08-31 | 2009-03-05 | Siemens Ag | Transferchuck zur Übertragung, insbesondere von Wafern |
| RU2662768C2 (ru) * | 2011-12-30 | 2018-07-31 | Гесвал с.а. | Рекомбинантный герпесвирус кои (khv) и вакцина для профилактики заболевания, вызываемого khv |
-
2012
- 2012-12-20 RU RU2014131474A patent/RU2662768C2/ru active
- 2012-12-20 MX MX2014008045A patent/MX361408B/es active IP Right Grant
- 2012-12-20 JP JP2014549442A patent/JP5982009B2/ja active Active
- 2012-12-20 US US14/368,093 patent/US20140348875A1/en not_active Abandoned
- 2012-12-20 HU HUE12806062A patent/HUE053075T2/hu unknown
- 2012-12-20 RS RS20201561A patent/RS61261B1/sr unknown
- 2012-12-20 WO PCT/EP2012/076496 patent/WO2013098214A1/en active Application Filing
- 2012-12-20 CN CN201280065496.XA patent/CN104159609B/zh active Active
- 2012-12-20 UA UAA201408626A patent/UA114719C2/uk unknown
- 2012-12-20 EP EP12806062.1A patent/EP2797627B1/en active Active
- 2012-12-20 PL PL12806062T patent/PL2797627T3/pl unknown
- 2012-12-20 BR BR112014016117-8A patent/BR112014016117A2/pt not_active Application Discontinuation
- 2012-12-20 SG SG11201403066TA patent/SG11201403066TA/en unknown
- 2012-12-20 UA UAA201702576A patent/UA119786C2/uk unknown
- 2012-12-27 MD MDA20120127A patent/MD4481C1/ro not_active IP Right Cessation
- 2012-12-28 TW TW101150791A patent/TWI484034B/zh not_active IP Right Cessation
-
2014
- 2014-06-01 IL IL232902A patent/IL232902A0/en unknown
- 2014-06-18 PH PH12014501388A patent/PH12014501388A1/en unknown
- 2014-06-19 IN IN4655CHN2014 patent/IN2014CN04655A/en unknown
-
2016
- 2016-04-14 JP JP2016081363A patent/JP2016195593A/ja active Pending
- 2016-05-25 US US15/164,010 patent/US9931396B2/en active Active
-
2018
- 2018-01-11 JP JP2018002936A patent/JP2018078903A/ja not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| RS61261B1 (sr) | 2021-01-29 |
| MD4481B1 (ro) | 2017-05-31 |
| MX361408B (es) | 2018-12-04 |
| JP5982009B2 (ja) | 2016-08-31 |
| CN104159609B (zh) | 2018-05-22 |
| TWI484034B (zh) | 2015-05-11 |
| RU2662768C2 (ru) | 2018-07-31 |
| EP2797627A1 (en) | 2014-11-05 |
| CN104159609A (zh) | 2014-11-19 |
| EP2797627B1 (en) | 2020-10-07 |
| PH12014501388A1 (en) | 2014-09-22 |
| JP2016195593A (ja) | 2016-11-24 |
| US20140348875A1 (en) | 2014-11-27 |
| JP2018078903A (ja) | 2018-05-24 |
| IN2014CN04655A (mo) | 2015-09-18 |
| IL232902A0 (en) | 2014-07-31 |
| TW201333201A (zh) | 2013-08-16 |
| JP2015503914A (ja) | 2015-02-05 |
| BR112014016117A2 (pt) | 2018-09-25 |
| US9931396B2 (en) | 2018-04-03 |
| HUE053075T2 (hu) | 2021-06-28 |
| UA114719C2 (uk) | 2017-07-25 |
| MD4481C1 (ro) | 2017-12-31 |
| PL2797627T3 (pl) | 2021-06-28 |
| UA119786C2 (uk) | 2019-08-12 |
| WO2013098214A1 (en) | 2013-07-04 |
| US20170028057A1 (en) | 2017-02-02 |
| RU2014131474A (ru) | 2016-02-20 |
| MX2014008045A (es) | 2014-10-24 |
| SG11201403066TA (en) | 2014-10-30 |
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| TH158445A (th) | รีคอมบิแนนท์คอยเฮอร์ปีส์ไวรัส (khv) และวัคซีนสำหรับการป้องกันของโรคที่ได้รับการทำให้เกิดขึ้นโดย khv |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| GB9A | Change of applicant (patent for invention) |
Owner name: GESVAL S.A., BE AVENUE PRE-AILY, 4, B-4031 ANGLEUR Free format text: PREVIOUS APPLICANT: UNIVERSITE DE LIEGE, BE AVENUE PRE-AILY, 4, B-4031 ANGLEUR, BELGIA |
|
| FG4A | Patent for invention issued | ||
| KA4A | Patent for invention lapsed due to non-payment of fees (with right of restoration) | ||
| MM4A | Patent for invention definitely lapsed due to non-payment of fees |