WO2013093629A3 - Modular vaccines, methods and compositions related thereto - Google Patents

Modular vaccines, methods and compositions related thereto Download PDF

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Publication number
WO2013093629A3
WO2013093629A3 PCT/IB2012/003006 IB2012003006W WO2013093629A3 WO 2013093629 A3 WO2013093629 A3 WO 2013093629A3 IB 2012003006 W IB2012003006 W IB 2012003006W WO 2013093629 A3 WO2013093629 A3 WO 2013093629A3
Authority
WO
WIPO (PCT)
Prior art keywords
methods
vaccines
treatment
compositions related
modular
Prior art date
Application number
PCT/IB2012/003006
Other languages
French (fr)
Other versions
WO2013093629A2 (en
Inventor
Koen OOSTERHUIS
Jan Batist Anna Gerardus HAANEN
Antonius Nicolaas Maria Schumacher
Original Assignee
Netherlands Cancer Institute
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Netherlands Cancer Institute filed Critical Netherlands Cancer Institute
Publication of WO2013093629A2 publication Critical patent/WO2013093629A2/en
Publication of WO2013093629A3 publication Critical patent/WO2013093629A3/en

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/385—Haptens or antigens, bound to carriers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/53—DNA (RNA) vaccination
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/58—Medicinal preparations containing antigens or antibodies raising an immune response against a target which is not the antigen used for immunisation
    • A61K2039/585—Medicinal preparations containing antigens or antibodies raising an immune response against a target which is not the antigen used for immunisation wherein the target is cancer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6031—Proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/62—Medicinal preparations containing antigens or antibodies characterised by the link between antigen and carrier
    • A61K2039/627—Medicinal preparations containing antigens or antibodies characterised by the link between antigen and carrier characterised by the linker
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/20011—Papillomaviridae
    • C12N2710/20034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

Abstract

The invention relates to the field of methods and related compositions for the preparation and administration of vaccines, such as DNA vaccines, for the treatment of one or more diseases. In other embodiments, the invention relates to the field of methods for the prevention or treatment of disease comprising administration of one or more vaccines, such as DNA vaccines, for the treatment of a disease to a patient in need thereof. In a particular embodiment, the invention provides a DNA vaccine for the prevention and treatment of HPV and/or an HPV -induced cancer.
PCT/IB2012/003006 2011-12-20 2012-12-19 Modular vaccines, methods and compositions related thereto WO2013093629A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201161577811P 2011-12-20 2011-12-20
US61/577,811 2011-12-20

Publications (2)

Publication Number Publication Date
WO2013093629A2 WO2013093629A2 (en) 2013-06-27
WO2013093629A3 true WO2013093629A3 (en) 2014-01-16

Family

ID=48014103

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB2012/003006 WO2013093629A2 (en) 2011-12-20 2012-12-19 Modular vaccines, methods and compositions related thereto

Country Status (1)

Country Link
WO (1) WO2013093629A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2955250A1 (en) 2014-07-16 2016-01-21 Moderna Therapeutics, Inc. Chimeric polynucleotides

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