MD1743B2 - Derivaţi ai indolului, procedeu de obţinere a lor, compoziţie fungicidă şi procedeu de combatere a fungilor - Google Patents

Derivaţi ai indolului, procedeu de obţinere a lor, compoziţie fungicidă şi procedeu de combatere a fungilor

Info

Publication number
MD1743B2
MD1743B2 MD96-0305A MD960305A MD1743B2 MD 1743 B2 MD1743 B2 MD 1743B2 MD 960305 A MD960305 A MD 960305A MD 1743 B2 MD1743 B2 MD 1743B2
Authority
MD
Moldova
Prior art keywords
group
preparation
fungicidal composition
indole derivatives
alkyl
Prior art date
Application number
MD96-0305A
Other languages
English (en)
Russian (ru)
Inventor
Jurgen Curtze
Guido Albert
Original Assignee
Shell Internationale Research Maatschappij B.V.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shell Internationale Research Maatschappij B.V. filed Critical Shell Internationale Research Maatschappij B.V.
Publication of MD1743B2 publication Critical patent/MD1743B2/ro

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/34—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom
    • A01N43/36—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom five-membered rings
    • A01N43/38—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom five-membered rings condensed with carbocyclic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Dentistry (AREA)
  • Wood Science & Technology (AREA)
  • Plant Pathology (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Agronomy & Crop Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Pest Control & Pesticides (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Indole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Invenţia se referă la derivaţi ai indolului, procedeu de obţinere a lor, compoziţie fungicidă şi procedeu de combatere a fungilor în focar.Derivatul indolului este prezentat prin formula generală (I),( I )în care R reprezintă o grupă fenil substituită;R3 şi R4, independent, reprezintă atomul de hidrogen sau halogen sau o grupă: alchil, alcoxi, cicloalchil, fenil sau fenoxi, opţional substituită;R5 şi R6, independent, reprezintă atomul de hidrogen sau o grupă: alchil, alcoxi, cicloalchil, fenil sau fenoxi, opţional substituită, sau R5 şi R6 împreună cu atomul de azot intermediar reprezintă grupa eterociclil;R7 reprezintă atomul de hidrogen sau grupa alchil.
MD96-0305A 1992-06-05 1993-06-03 Derivaţi ai indolului, procedeu de obţinere a lor, compoziţie fungicidă şi procedeu de combatere a fungilor MD1743B2 (ro)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP92109525 1992-06-05
PCT/EP1993/001406 WO1993025524A1 (en) 1992-06-05 1993-06-03 Fungicidal indole derivatives

Publications (1)

Publication Number Publication Date
MD1743B2 true MD1743B2 (ro) 2001-09-30

Family

ID=8209683

Family Applications (1)

Application Number Title Priority Date Filing Date
MD96-0305A MD1743B2 (ro) 1992-06-05 1993-06-03 Derivaţi ai indolului, procedeu de obţinere a lor, compoziţie fungicidă şi procedeu de combatere a fungilor

Country Status (17)

Country Link
US (1) US5399559A (ro)
EP (1) EP0643695B1 (ro)
JP (1) JP3296490B2 (ro)
CN (1) CN1082318A (ro)
AT (1) ATE141260T1 (ro)
AU (1) AU666558B2 (ro)
DE (1) DE69304057T2 (ro)
DK (1) DK0643695T3 (ro)
ES (1) ES2091615T3 (ro)
GE (1) GEP19981431B (ro)
GR (1) GR3020807T3 (ro)
HU (1) HU216814B (ro)
IL (1) IL105909A (ro)
MD (1) MD1743B2 (ro)
TW (1) TW229140B (ro)
WO (1) WO1993025524A1 (ro)
ZA (1) ZA933846B (ro)

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KR100231956B1 (ko) * 1995-08-04 1999-12-01 오쯔까 유우지로 인돌-2-카복실산 에스테르 유도체 및 활성 성분으로서 이를 함유하는 농업용 및 원예용 살균제
US6353007B1 (en) * 2000-07-13 2002-03-05 Boehringer Ingelheim Pharmaceuticals, Inc. Substituted 1-(4-aminophenyl)indoles and their use as anti-inflammatory agents
EP1314733A1 (en) * 2001-11-22 2003-05-28 Aventis Pharma Deutschland GmbH Indole-2-carboxamides as factor Xa inhibitors
EP1479677A1 (en) 2003-05-19 2004-11-24 Aventis Pharma Deutschland GmbH New indole derivatives as factor xa inhibitors
SE0302035D0 (sv) * 2003-07-09 2003-07-09 Biolipox Ab New compound
CA2570365A1 (en) * 2004-06-18 2005-12-29 Biolipox Ab Indoles useful in the treatment of inflammation
DE602005009209D1 (de) 2004-06-18 2008-10-02 Biolipox Ab Zur behandlung von entzündungen geeignete indole
CA2570531A1 (en) * 2004-06-18 2005-12-29 Kristofer Olofsson Indoles useful in the treatment of inflammation
ATE501119T1 (de) * 2005-01-19 2011-03-15 Biolipox Ab Entzündungshemmende indol-derivate
EP1844051A1 (en) * 2005-01-19 2007-10-17 Biolipox AB Thienopyrroles useful in the treatment of inflammation
WO2006077364A1 (en) * 2005-01-19 2006-07-27 Biolipox Ab Indoles useful in the treatment of inflammation
US20100197687A1 (en) * 2005-01-19 2010-08-05 Benjamin Pelcman Indoles Useful in the Treatment of Inflammation
WO2006077401A1 (en) * 2005-01-19 2006-07-27 Biolipox Ab Pyrrolopyridines useful in the treatment of inflammation
US20090042949A1 (en) * 2005-01-19 2009-02-12 Benjamin Pelcman Indoles Useful in the Treatment of Inflammation
AR056690A1 (es) 2005-10-14 2007-10-17 Athersys Inc Derivados de indol como inhibidores de indol como inhibidores del receptor 3 de histamina para el tartamiento de trastornos del sueno y cognitivos obesidad y otros trastornos de snc
WO2007109178A2 (en) * 2006-03-16 2007-09-27 Pharmacyclics, Inc. Indole derivatives as inhibitors of histone deacetylase
EA020332B1 (ru) * 2007-08-10 2014-10-30 Х. Лундбекк А/С Аналоги гетероариламидов
ME01838B (me) 2009-06-29 2014-12-20 Lncyte Holdings Corp Pirimidinoni kao inhibitori pi3k
US8759359B2 (en) 2009-12-18 2014-06-24 Incyte Corporation Substituted heteroaryl fused derivatives as PI3K inhibitors
EP2558463A1 (en) 2010-04-14 2013-02-20 Incyte Corporation Fused derivatives as i3 inhibitors
US9062055B2 (en) 2010-06-21 2015-06-23 Incyte Corporation Fused pyrrole derivatives as PI3K inhibitors
EP2655374B1 (en) 2010-12-20 2019-10-23 Incyte Holdings Corporation N-(1-(substituted-phenyl)ethyl)-9h-purin-6-amines as pi3k inhibitors
US9108984B2 (en) 2011-03-14 2015-08-18 Incyte Corporation Substituted diamino-pyrimidine and diamino-pyridine derivatives as PI3K inhibitors
WO2012135009A1 (en) 2011-03-25 2012-10-04 Incyte Corporation Pyrimidine-4,6-diamine derivatives as pi3k inhibitors
KR102371532B1 (ko) 2011-09-02 2022-03-07 인사이트 홀딩스 코포레이션 Ｐｉ３ｋ 억제제로서 헤테로시클릴아민
AR090548A1 (es) 2012-04-02 2014-11-19 Incyte Corp Azaheterociclobencilaminas biciclicas como inhibidores de pi3k
US10077277B2 (en) 2014-06-11 2018-09-18 Incyte Corporation Bicyclic heteroarylaminoalkyl phenyl derivatives as PI3K inhibitors
NZ734993A (en) 2015-02-27 2024-03-22 Incyte Holdings Corp Salts of pi3k inhibitor and processes for their preparation
US9732097B2 (en) 2015-05-11 2017-08-15 Incyte Corporation Process for the synthesis of a phosphoinositide 3-kinase inhibitor
US9988401B2 (en) 2015-05-11 2018-06-05 Incyte Corporation Crystalline forms of a PI3K inhibitor
WO2024026290A1 (en) * 2022-07-25 2024-02-01 Cayman Chemical Company Incorporated NOVEL HETEROCYCLES AS sPLA2-X INHIBITORS

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DE2008692A1 (de) * 1969-02-26 1970-09-17 Agence Nationale de Valorisation de La Recherche (ANVAR), Puteaux, Hautsde-Seine (Prankreich) Verfahren zur Herstellung von Indol-3carbonsäurederivaten und nach dem Verfahren erhältliche, neue Verbindungen
DE1966206A1 (de) * 1968-04-26 1972-01-20 Sumitomo Chemical Co 1,4-Benzodiazepine und Arzneipraeparate
JPH0570357A (ja) * 1991-09-12 1993-03-23 Fuso Yakuhin Kogyo Kk 血液透析用顆粒剤
JPH0570358A (ja) * 1991-09-10 1993-03-23 Kao Corp 象牙質知覚過敏治療剤

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DE1935671C3 (de) * 1968-04-26 1975-01-09 Sumitomo Chemical Co 2-Aminomethylindole und ihre Salze
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EP0211698B1 (fr) * 1985-02-08 1991-01-30 Synthelabo Dérivés de (dihydro-4,5 1H-imidazolyl-2)-2 dihydro-2,3 indole, leur préparation et leur application en thérapeutique
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Patent Citations (4)

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Publication number Priority date Publication date Assignee Title
DE1966206A1 (de) * 1968-04-26 1972-01-20 Sumitomo Chemical Co 1,4-Benzodiazepine und Arzneipraeparate
DE2008692A1 (de) * 1969-02-26 1970-09-17 Agence Nationale de Valorisation de La Recherche (ANVAR), Puteaux, Hautsde-Seine (Prankreich) Verfahren zur Herstellung von Indol-3carbonsäurederivaten und nach dem Verfahren erhältliche, neue Verbindungen
JPH0570358A (ja) * 1991-09-10 1993-03-23 Kao Corp 象牙質知覚過敏治療剤
JPH0570357A (ja) * 1991-09-12 1993-03-23 Fuso Yakuhin Kogyo Kk 血液透析用顆粒剤

Also Published As

Publication number Publication date
JPH07507323A (ja) 1995-08-10
ES2091615T3 (es) 1996-11-01
HUT69737A (en) 1995-09-28
AU666558B2 (en) 1996-02-15
TW229140B (ro) 1994-09-01
DE69304057T2 (de) 1997-02-06
JP3296490B2 (ja) 2002-07-02
DK0643695T3 (da) 1996-09-02
HU9403475D0 (en) 1995-03-28
EP0643695B1 (en) 1996-08-14
CN1082318A (zh) 1994-02-23
EP0643695A1 (en) 1995-03-22
US5399559A (en) 1995-03-21
IL105909A (en) 1997-04-15
WO1993025524A1 (en) 1993-12-23
IL105909A0 (en) 1993-10-20
ATE141260T1 (de) 1996-08-15
DE69304057D1 (de) 1996-09-19
AU4322693A (en) 1994-01-04
GR3020807T3 (en) 1996-11-30
ZA933846B (en) 1993-12-28
HU216814B (hu) 1999-08-30
GEP19981431B (en) 1998-10-30

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Legal Events

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PD99 Pending application