CN1082318A - 杀真菌的吲哚衍生物 - Google Patents

杀真菌的吲哚衍生物 Download PDF

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Publication number
CN1082318A
CN1082318A CN93108296A CN93108296A CN1082318A CN 1082318 A CN1082318 A CN 1082318A CN 93108296 A CN93108296 A CN 93108296A CN 93108296 A CN93108296 A CN 93108296A CN 1082318 A CN1082318 A CN 1082318A
Authority
CN
China
Prior art keywords
phenyl
group
alkyl
hydrogen atom
methyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN93108296A
Other languages
English (en)
Chinese (zh)
Inventor
J·柯茨
G·阿尔博特
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Shell Internationale Research Maatschappij BV
Original Assignee
Shell Internationale Research Maatschappij BV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shell Internationale Research Maatschappij BV filed Critical Shell Internationale Research Maatschappij BV
Publication of CN1082318A publication Critical patent/CN1082318A/zh
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/34—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom
    • A01N43/36—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom five-membered rings
    • A01N43/38—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom five-membered rings condensed with carbocyclic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Agronomy & Crop Science (AREA)
  • Pest Control & Pesticides (AREA)
  • Plant Pathology (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Dentistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Indole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CN93108296A 1992-06-05 1993-06-04 杀真菌的吲哚衍生物 Pending CN1082318A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP92109525.3 1992-06-05
EP92109525 1992-06-05

Publications (1)

Publication Number Publication Date
CN1082318A true CN1082318A (zh) 1994-02-23

Family

ID=8209683

Family Applications (1)

Application Number Title Priority Date Filing Date
CN93108296A Pending CN1082318A (zh) 1992-06-05 1993-06-04 杀真菌的吲哚衍生物

Country Status (17)

Country Link
US (1) US5399559A (ro)
EP (1) EP0643695B1 (ro)
JP (1) JP3296490B2 (ro)
CN (1) CN1082318A (ro)
AT (1) ATE141260T1 (ro)
AU (1) AU666558B2 (ro)
DE (1) DE69304057T2 (ro)
DK (1) DK0643695T3 (ro)
ES (1) ES2091615T3 (ro)
GE (1) GEP19981431B (ro)
GR (1) GR3020807T3 (ro)
HU (1) HU216814B (ro)
IL (1) IL105909A (ro)
MD (1) MD1743B2 (ro)
TW (1) TW229140B (ro)
WO (1) WO1993025524A1 (ro)
ZA (1) ZA933846B (ro)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101778850A (zh) * 2007-08-10 2010-07-14 H.隆德贝克有限公司 杂芳基酰胺类似物
CN118546085A (zh) * 2024-07-25 2024-08-27 西北农林科技大学深圳研究院 植物病害防治组合物及其制备方法和应用

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US5866594A (en) * 1995-08-04 1999-02-02 Otsuka Kagaku Kabushiki Kaisha Indole-2-carboxylate derivatives and fungicidal compositions for agricultural or horticultural use containing the derivatives as active component
US6353007B1 (en) * 2000-07-13 2002-03-05 Boehringer Ingelheim Pharmaceuticals, Inc. Substituted 1-(4-aminophenyl)indoles and their use as anti-inflammatory agents
EP1314733A1 (en) * 2001-11-22 2003-05-28 Aventis Pharma Deutschland GmbH Indole-2-carboxamides as factor Xa inhibitors
EP1479677A1 (en) 2003-05-19 2004-11-24 Aventis Pharma Deutschland GmbH New indole derivatives as factor xa inhibitors
SE0302035D0 (sv) * 2003-07-09 2003-07-09 Biolipox Ab New compound
EP1778632B1 (en) 2004-06-18 2008-08-20 Biolipox AB Indoles useful in the treatment of inflammation
JP2008502672A (ja) * 2004-06-18 2008-01-31 バイオリポックス エービー 炎症の治療に有用なインドール類
KR20070029809A (ko) * 2004-06-18 2007-03-14 바이올리폭스 에이비 염증치료에 유용한 인돌
WO2006077412A1 (en) * 2005-01-19 2006-07-27 Biolipox Ab Thienopyrroles useful in the treatment of inflammation
EP1838669A1 (en) * 2005-01-19 2007-10-03 Biolipox AB Indoles useful in the treatment of inflammation
CA2594777A1 (en) * 2005-01-19 2006-07-27 Biolipox Ab Indoles useful in the treatment of inflamation
EP1844013A1 (en) * 2005-01-19 2007-10-17 Biolipox AB Indoles useful in the treatment of inflammation
JP2008527029A (ja) 2005-01-19 2008-07-24 バイオリポックス エービー 炎症の治療に有用なインドール類
WO2006077401A1 (en) * 2005-01-19 2006-07-27 Biolipox Ab Pyrrolopyridines useful in the treatment of inflammation
AR056690A1 (es) 2005-10-14 2007-10-17 Athersys Inc Derivados de indol como inhibidores de indol como inhibidores del receptor 3 de histamina para el tartamiento de trastornos del sueno y cognitivos obesidad y otros trastornos de snc
WO2007109178A2 (en) * 2006-03-16 2007-09-27 Pharmacyclics, Inc. Indole derivatives as inhibitors of histone deacetylase
EP2845856A1 (en) 2009-06-29 2015-03-11 Incyte Corporation Pyrimidinones as PI3K inhibitors
US8759359B2 (en) 2009-12-18 2014-06-24 Incyte Corporation Substituted heteroaryl fused derivatives as PI3K inhibitors
AR081823A1 (es) 2010-04-14 2012-10-24 Incyte Corp DERIVADOS FUSIONADOS COMO INHIBIDORES DE PI3Kd
US9062055B2 (en) 2010-06-21 2015-06-23 Incyte Corporation Fused pyrrole derivatives as PI3K inhibitors
EP3660016A1 (en) 2010-12-20 2020-06-03 Incyte Holdings Corporation N-(1-(substituted-phenyl)ethyl)-9h-purin-6-amines as pi3k inhibitors
WO2012125629A1 (en) 2011-03-14 2012-09-20 Incyte Corporation Substituted diamino-pyrimidine and diamino-pyridine derivatives as pi3k inhibitors
WO2012135009A1 (en) 2011-03-25 2012-10-04 Incyte Corporation Pyrimidine-4,6-diamine derivatives as pi3k inhibitors
SG11201400232WA (en) 2011-09-02 2014-03-28 Incyte Corp Heterocyclylamines as pi3k inhibitors
AR090548A1 (es) 2012-04-02 2014-11-19 Incyte Corp Azaheterociclobencilaminas biciclicas como inhibidores de pi3k
WO2015191677A1 (en) 2014-06-11 2015-12-17 Incyte Corporation Bicyclic heteroarylaminoalkyl phenyl derivatives as pi3k inhibitors
EP3262046B1 (en) 2015-02-27 2020-11-04 Incyte Corporation Salts of pi3k inhibitor and processes for their preparation
US9988401B2 (en) 2015-05-11 2018-06-05 Incyte Corporation Crystalline forms of a PI3K inhibitor
US9732097B2 (en) 2015-05-11 2017-08-15 Incyte Corporation Process for the synthesis of a phosphoinositide 3-kinase inhibitor
WO2024026290A1 (en) * 2022-07-25 2024-02-01 Cayman Chemical Company Incorporated NOVEL HETEROCYCLES AS sPLA2-X INHIBITORS

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DE1935671C3 (de) * 1968-04-26 1975-01-09 Sumitomo Chemical Co 2-Aminomethylindole und ihre Salze
US3634402A (en) * 1968-04-26 1972-01-11 Sumitomo Chemical Co Process for producing 1 4-benzodiazepine derivatives and their salts
DE1966206A1 (de) * 1968-04-26 1972-01-20 Sumitomo Chemical Co 1,4-Benzodiazepine und Arzneipraeparate
GB1305458A (ro) * 1969-02-26 1973-01-31
US3582285A (en) * 1970-03-19 1971-06-01 Xerox Corp Chemical package
US4431307A (en) * 1981-11-19 1984-02-14 Labsystems Oy Set of cuvettes
US4599315A (en) * 1983-09-13 1986-07-08 University Of California Regents Microdroplet test apparatus
DE3677277D1 (de) * 1985-02-08 1991-03-07 Synthelabo (dihydro-4,5-1h-imidazolyl-2)-2-dihydro-2,3-indolderivate, ihre herstellung und anwendung als heilmittel.
US4925629A (en) * 1988-07-28 1990-05-15 Bioquant, Inc. Diagnostic device
US5147529A (en) * 1988-08-10 1992-09-15 E. I. Du Pont De Nemours And Company Method for automatically processing magnetic solid phase reagents
US5041266A (en) * 1989-12-21 1991-08-20 Hoffmann-La Roche Inc. Tray for immunometric determinations
JP2964182B2 (ja) * 1991-09-10 1999-10-18 花王株式会社 象牙質知覚過敏治療剤
JP2986256B2 (ja) * 1991-09-12 1999-12-06 扶桑薬品工業株式会社 血液透析用顆粒剤

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101778850A (zh) * 2007-08-10 2010-07-14 H.隆德贝克有限公司 杂芳基酰胺类似物
CN118546085A (zh) * 2024-07-25 2024-08-27 西北农林科技大学深圳研究院 植物病害防治组合物及其制备方法和应用

Also Published As

Publication number Publication date
ATE141260T1 (de) 1996-08-15
JPH07507323A (ja) 1995-08-10
IL105909A (en) 1997-04-15
WO1993025524A1 (en) 1993-12-23
GR3020807T3 (en) 1996-11-30
HUT69737A (en) 1995-09-28
MD1743B2 (ro) 2001-09-30
TW229140B (ro) 1994-09-01
DE69304057T2 (de) 1997-02-06
ZA933846B (en) 1993-12-28
IL105909A0 (en) 1993-10-20
GEP19981431B (en) 1998-10-30
AU4322693A (en) 1994-01-04
JP3296490B2 (ja) 2002-07-02
DK0643695T3 (da) 1996-09-02
ES2091615T3 (es) 1996-11-01
DE69304057D1 (de) 1996-09-19
EP0643695A1 (en) 1995-03-22
US5399559A (en) 1995-03-21
HU9403475D0 (en) 1995-03-28
HU216814B (hu) 1999-08-30
EP0643695B1 (en) 1996-08-14
AU666558B2 (en) 1996-02-15

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C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C01 Deemed withdrawal of patent application (patent law 1993)
WD01 Invention patent application deemed withdrawn after publication