MA56526B1 - Dérivés de pyrido [2,3-d] pyrimidine en tant qu'inhibiteurs de la réplication du virus de l'immunodéficience humaine - Google Patents
Dérivés de pyrido [2,3-d] pyrimidine en tant qu'inhibiteurs de la réplication du virus de l'immunodéficience humaineInfo
- Publication number
- MA56526B1 MA56526B1 MA56526A MA56526A MA56526B1 MA 56526 B1 MA56526 B1 MA 56526B1 MA 56526 A MA56526 A MA 56526A MA 56526 A MA56526 A MA 56526A MA 56526 B1 MA56526 B1 MA 56526B1
- Authority
- MA
- Morocco
- Prior art keywords
- immunodeficiency virus
- human immunodeficiency
- pyrido
- inhibitors
- virus replication
- Prior art date
Links
- 241000725303 Human immunodeficiency virus Species 0.000 title abstract 2
- 239000003112 inhibitor Substances 0.000 title 1
- 159000000018 pyrido[2,3-d]pyrimidines Chemical class 0.000 title 1
- 230000029812 viral genome replication Effects 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 208000015181 infectious disease Diseases 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/07—Optical isomers
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Virology (AREA)
- Oncology (AREA)
- General Chemical & Material Sciences (AREA)
- Tropical Medicine & Parasitology (AREA)
- Molecular Biology (AREA)
- AIDS & HIV (AREA)
- Communicable Diseases (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Dermatology (AREA)
- Physiology (AREA)
- Nutrition Science (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
L'invention concerne un composé et ses sels pharmaceutiquement acceptables, ainsi que des compositions et des méthodes de traitement d'une infection par le virus de l'immunodéficience humaine (vih).
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201962863406P | 2019-06-19 | 2019-06-19 | |
PCT/IB2020/055653 WO2020254985A1 (fr) | 2019-06-19 | 2020-06-17 | Dérivés de pyrido [2,3-d] pyrimidine en tant qu'inhibiteurs de la réplication du virus de l'immunodéficience humaine |
Publications (2)
Publication Number | Publication Date |
---|---|
MA56526A MA56526A (fr) | 2022-04-27 |
MA56526B1 true MA56526B1 (fr) | 2024-05-31 |
Family
ID=71738195
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MA56526A MA56526B1 (fr) | 2019-06-19 | 2020-06-17 | Dérivés de pyrido [2,3-d] pyrimidine en tant qu'inhibiteurs de la réplication du virus de l'immunodéficience humaine |
Country Status (29)
Country | Link |
---|---|
US (1) | US20210323967A1 (fr) |
EP (1) | EP3986561B1 (fr) |
JP (1) | JP2022537047A (fr) |
KR (1) | KR20220024608A (fr) |
CN (1) | CN114245795B (fr) |
AR (1) | AR119174A1 (fr) |
AU (1) | AU2020295793B2 (fr) |
BR (1) | BR112021025655A2 (fr) |
CA (1) | CA3143136A1 (fr) |
CL (1) | CL2021003388A1 (fr) |
CO (1) | CO2021017479A2 (fr) |
CR (1) | CR20210664A (fr) |
DK (1) | DK3986561T3 (fr) |
ES (1) | ES2974541T3 (fr) |
FI (1) | FI3986561T3 (fr) |
HR (1) | HRP20240501T1 (fr) |
HU (1) | HUE065762T2 (fr) |
IL (1) | IL288750A (fr) |
LT (1) | LT3986561T (fr) |
MA (1) | MA56526B1 (fr) |
MD (1) | MD3986561T2 (fr) |
MX (1) | MX2021016149A (fr) |
PE (1) | PE20220510A1 (fr) |
PL (1) | PL3986561T3 (fr) |
PT (1) | PT3986561T (fr) |
RS (1) | RS65304B1 (fr) |
SI (1) | SI3986561T1 (fr) |
UY (1) | UY38755A (fr) |
WO (1) | WO2020254985A1 (fr) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EA202190854A1 (ru) | 2018-10-24 | 2021-08-17 | ВАЙВ ХЕЛТКЕР ЮКей (№5) ЛИМИТЕД | Ингибиторы репликации вируса иммунодефицита человека |
WO2021116872A1 (fr) * | 2019-12-09 | 2021-06-17 | Viiv Healthcare Company | Compositions pharmaceutiques contenant du cabotégravir |
AU2021231447A1 (en) * | 2020-03-06 | 2022-09-22 | VIIV Healthcare UK (No.5) Limited | Inhibitors of human immunodeficiency virus replication |
AU2022362855A1 (en) | 2021-10-13 | 2024-05-02 | VIIV Healthcare UK (No.5) Limited | Inhibitors of human immunodeficiency virus replication |
Family Cites Families (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
MX2011000149A (es) * | 2008-07-02 | 2011-02-24 | Avexa Ltd | Compuestos que tienen propiedades antivirales. |
CN102464654B (zh) | 2010-11-12 | 2016-01-13 | 上海泓博智源医药技术有限公司 | 抗病毒化合物 |
WO2013006738A1 (fr) | 2011-07-06 | 2013-01-10 | Gilead Sciences, Inc. | Composés pour traiter le vih |
CN102863512B (zh) | 2011-07-07 | 2016-04-20 | 上海泓博智源医药技术有限公司 | 抗病毒化合物 |
PT2943487T (pt) | 2013-01-09 | 2016-12-15 | Gilead Sciences Inc | Heteroarilos de 5 membros e sua utilização como agentes antivirais |
TW201443037A (zh) | 2013-01-09 | 2014-11-16 | Gilead Sciences Inc | 治療用化合物 |
EP2943493B1 (fr) | 2013-01-09 | 2017-08-02 | Gilead Sciences, Inc. | Composés thérapeutiques pour le traitement d'infections virales |
TWI694071B (zh) | 2013-03-01 | 2020-05-21 | 美商基利科學股份有限公司 | 治療反轉錄病毒科(Retroviridae)病毒感染之治療性化合物 |
WO2015130966A1 (fr) | 2014-02-28 | 2015-09-03 | Gilead Sciences, Inc. | Agents antiviraux |
US10202353B2 (en) | 2014-02-28 | 2019-02-12 | Gilead Sciences, Inc. | Therapeutic compounds |
NZ729150A (en) | 2014-08-29 | 2018-02-23 | Gilead Sciences Inc | Antiretroviral agents |
PL3597646T3 (pl) * | 2016-08-19 | 2023-12-11 | Gilead Sciences, Inc. | Związki terapeutyczne użyteczne do profilaktycznego lub terapeutycznego leczenia zakażenia wirusem HIV |
ES2826748T3 (es) * | 2016-09-02 | 2021-05-19 | Gilead Sciences Inc | Derivados de 4,6-diamino-pirido[3,2-d]pirimidina como moduladores de receptores de tipo Toll |
TW201906834A (zh) * | 2017-05-02 | 2019-02-16 | 英商Viiv醫療保健英國(No.5)有限公司 | 人類免疫不全病毒複製之抑制劑 |
UY38559A (es) * | 2019-02-01 | 2020-07-31 | Viiv Healthcare Uk No 5 Ltd | Inhibidores de la replicación del virus de la inmunodeficiencia humana |
-
2020
- 2020-06-17 DK DK20743783.1T patent/DK3986561T3/da active
- 2020-06-17 UY UY0001038755A patent/UY38755A/es unknown
- 2020-06-17 CN CN202080052305.0A patent/CN114245795B/zh active Active
- 2020-06-17 PE PE2021002114A patent/PE20220510A1/es unknown
- 2020-06-17 CR CR20210664A patent/CR20210664A/es unknown
- 2020-06-17 HR HRP20240501TT patent/HRP20240501T1/hr unknown
- 2020-06-17 JP JP2021575482A patent/JP2022537047A/ja active Pending
- 2020-06-17 SI SI202030385T patent/SI3986561T1/sl unknown
- 2020-06-17 BR BR112021025655A patent/BR112021025655A2/pt unknown
- 2020-06-17 AU AU2020295793A patent/AU2020295793B2/en active Active
- 2020-06-17 MX MX2021016149A patent/MX2021016149A/es unknown
- 2020-06-17 MA MA56526A patent/MA56526B1/fr unknown
- 2020-06-17 KR KR1020227001501A patent/KR20220024608A/ko unknown
- 2020-06-17 CA CA3143136A patent/CA3143136A1/fr active Pending
- 2020-06-17 ES ES20743783T patent/ES2974541T3/es active Active
- 2020-06-17 PT PT207437831T patent/PT3986561T/pt unknown
- 2020-06-17 FI FIEP20743783.1T patent/FI3986561T3/fi active
- 2020-06-17 HU HUE20743783A patent/HUE065762T2/hu unknown
- 2020-06-17 WO PCT/IB2020/055653 patent/WO2020254985A1/fr active Application Filing
- 2020-06-17 AR ARP200101700A patent/AR119174A1/es unknown
- 2020-06-17 PL PL20743783.1T patent/PL3986561T3/pl unknown
- 2020-06-17 EP EP20743783.1A patent/EP3986561B1/fr active Active
- 2020-06-17 LT LTEPPCT/IB2020/055653T patent/LT3986561T/lt unknown
- 2020-06-17 US US17/268,107 patent/US20210323967A1/en active Pending
- 2020-06-17 RS RS20240309A patent/RS65304B1/sr unknown
- 2020-06-17 MD MDE20220479T patent/MD3986561T2/ro unknown
-
2021
- 2021-12-07 IL IL288750A patent/IL288750A/en unknown
- 2021-12-17 CL CL2021003388A patent/CL2021003388A1/es unknown
- 2021-12-20 CO CONC2021/0017479A patent/CO2021017479A2/es unknown
Also Published As
Publication number | Publication date |
---|---|
CL2021003388A1 (es) | 2022-09-30 |
CN114245795A (zh) | 2022-03-25 |
LT3986561T (lt) | 2024-04-25 |
EP3986561B1 (fr) | 2024-02-14 |
BR112021025655A2 (pt) | 2022-02-01 |
CN114245795B (zh) | 2024-08-06 |
CR20210664A (es) | 2022-01-21 |
JP2022537047A (ja) | 2022-08-23 |
IL288750A (en) | 2022-02-01 |
HRP20240501T1 (hr) | 2024-07-05 |
AU2020295793A1 (en) | 2022-01-20 |
DK3986561T3 (da) | 2024-03-04 |
RS65304B1 (sr) | 2024-04-30 |
CA3143136A1 (fr) | 2020-12-24 |
UY38755A (es) | 2020-11-30 |
MA56526A (fr) | 2022-04-27 |
PL3986561T3 (pl) | 2024-06-10 |
MD3986561T2 (ro) | 2024-06-30 |
US20210323967A1 (en) | 2021-10-21 |
MX2021016149A (es) | 2022-05-18 |
CO2021017479A2 (es) | 2022-04-19 |
AR119174A1 (es) | 2021-12-01 |
TW202115055A (zh) | 2021-04-16 |
PT3986561T (pt) | 2024-03-15 |
FI3986561T3 (fi) | 2024-05-02 |
WO2020254985A1 (fr) | 2020-12-24 |
EP3986561A1 (fr) | 2022-04-27 |
SI3986561T1 (sl) | 2024-04-30 |
HUE065762T2 (hu) | 2024-06-28 |
KR20220024608A (ko) | 2022-03-03 |
PE20220510A1 (es) | 2022-04-07 |
ES2974541T3 (es) | 2024-06-27 |
AU2020295793B2 (en) | 2023-07-06 |
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