MA52888A - Composés de benzènesulfonamide et leur utilisation en tant qu'agents thérapeutiques - Google Patents
Composés de benzènesulfonamide et leur utilisation en tant qu'agents thérapeutiquesInfo
- Publication number
- MA52888A MA52888A MA052888A MA52888A MA52888A MA 52888 A MA52888 A MA 52888A MA 052888 A MA052888 A MA 052888A MA 52888 A MA52888 A MA 52888A MA 52888 A MA52888 A MA 52888A
- Authority
- MA
- Morocco
- Prior art keywords
- therapeutic agents
- benzene sulfonamide
- sulfonamide compounds
- compounds
- benzene
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/08—Bridged systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/407—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with other heterocyclic ring systems, e.g. ketorolac, physostigmine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/38—Nitrogen atoms
- C07D277/50—Nitrogen atoms bound to hetero atoms
- C07D277/52—Nitrogen atoms bound to hetero atoms to sulfur atoms, e.g. sulfonamides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Biomedical Technology (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Pain & Pain Management (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201862684436P | 2018-06-13 | 2018-06-13 |
Publications (1)
Publication Number | Publication Date |
---|---|
MA52888A true MA52888A (fr) | 2021-04-21 |
Family
ID=67138087
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MA052888A MA52888A (fr) | 2018-06-13 | 2019-06-13 | Composés de benzènesulfonamide et leur utilisation en tant qu'agents thérapeutiques |
Country Status (23)
Country | Link |
---|---|
US (2) | US10745392B2 (fr) |
EP (1) | EP3807281A1 (fr) |
JP (2) | JP7371029B2 (fr) |
KR (1) | KR20210019507A (fr) |
CN (1) | CN112262142B (fr) |
AU (1) | AU2019285184B2 (fr) |
BR (1) | BR112020024729A2 (fr) |
CA (1) | CA3103600A1 (fr) |
CL (1) | CL2020003197A1 (fr) |
CR (1) | CR20200613A (fr) |
EA (1) | EA202092719A1 (fr) |
EC (1) | ECSP20079861A (fr) |
IL (1) | IL278949B2 (fr) |
JO (1) | JOP20200304A1 (fr) |
MA (1) | MA52888A (fr) |
MX (1) | MX2020013317A (fr) |
NI (1) | NI202000098A (fr) |
PE (1) | PE20211389A1 (fr) |
PH (1) | PH12020552111A1 (fr) |
SA (1) | SA520420768B1 (fr) |
SG (1) | SG11202011862PA (fr) |
UA (1) | UA127024C2 (fr) |
WO (1) | WO2019241533A1 (fr) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
TN2018000385A1 (en) * | 2016-05-20 | 2020-06-15 | Xenon Pharmaceuticals Inc | Benzenesulfonamide compounds and their use as therapeutic agents |
BR112019011121A2 (pt) | 2016-12-09 | 2019-10-01 | Xenon Pharmaceuticals Inc | compostos de benzenossulfonamida e seu uso como agentes terapêuticos |
UA127024C2 (uk) | 2018-06-13 | 2023-03-15 | Ксенон Фармасьютікалз Інк. | Бензолсульфонамідні сполуки та їх застосування як терапевтичних агентів |
CN112638879B (zh) | 2018-08-31 | 2024-06-18 | 泽农医药公司 | 杂芳基取代的磺酰胺化合物及其作为治疗剂的用途 |
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US5877193A (en) | 1996-07-19 | 1999-03-02 | Hoffmann-La Roche Inc. | Use of N-(4-aryl-thiazol-2-yl)-sulfonamides |
IL132702A0 (en) | 1997-05-07 | 2001-03-19 | Galen Chemicals Ltd | Intravaginal drug delivery devices for the administration of testosterone and testosterone precursors |
CA2349832A1 (fr) | 1999-01-13 | 2000-07-20 | Warner-Lambert Company | Derives de benzenesulfonamide et leur utilisation comme inhibiteurs de mek |
DE19907385A1 (de) | 1999-02-20 | 2000-08-24 | Boehringer Ingelheim Pharma | Neue substituierte 3-Phenoxy- und 3-Phenylalkyloxy-2-phenyl-propylamine |
AU5912500A (en) | 1999-07-16 | 2001-02-05 | Warner-Lambert Company | Method for treating chronic pain using mek inhibitors |
GB9928568D0 (en) | 1999-12-03 | 2000-02-02 | Zeneca Ltd | Chemical compounds |
FR2836917B1 (fr) | 2002-03-11 | 2006-02-24 | Lipha | Derives nitroso de la diphenylamine, compositions pharmaceutiques les contenant en tant que medicaments utilisables dans le traitement des pathologies caracterisees par une situation de stress oxydatif |
MXPA05000130A (es) | 2002-06-27 | 2005-02-17 | Novo Nordisk As | Derivados de aril-carbonilo como agentes terapeuticos. |
JP2005162726A (ja) | 2003-01-24 | 2005-06-23 | Tanabe Seiyaku Co Ltd | ピラゾロピリミジン化合物およびその製法 |
WO2004092123A2 (fr) | 2003-04-10 | 2004-10-28 | Microbia, Inc. | Inhibiteurs d'invasion fongique |
WO2005000309A2 (fr) | 2003-06-27 | 2005-01-06 | Ionix Pharmaceuticals Limited | Composes chimiques |
EP1646628A1 (fr) | 2003-07-08 | 2006-04-19 | Novartis AG | Composes benzenesulfonylamino, et compositions pharmaceutiques contenant ces composes |
EP2332912A1 (fr) | 2003-08-08 | 2011-06-15 | Vertex Pharmaceuticals Incorporated | Compositions utilisees comme inhibiteurs de canaux sodium voltage dependants |
HU227684B1 (en) | 2003-08-29 | 2011-11-28 | Sanofi Aventis | Adamantane and azabicyclo-octane and nonane derivatives and their use as dpp-iv inhibitors |
EP1888544A2 (fr) | 2004-12-17 | 2008-02-20 | Takeda San Diego, Inc. | Inhibiteurs des hydroxystéroides déshydrogénases |
GB0510139D0 (en) | 2005-05-18 | 2005-06-22 | Addex Pharmaceuticals Sa | Novel compounds B1 |
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EP2054385A2 (fr) | 2006-08-15 | 2009-05-06 | F. Hoffmann-Roche AG | Dérivés phényliques, de la pyridine et de la quinoléine |
MX2009004019A (es) | 2006-10-19 | 2009-06-19 | Signal Pharm Llc | Compuestos heteroarilo, composiciones de los mismos, y uso de los mismos como inhibidores de proteina cinasa. |
JP5463285B2 (ja) | 2007-07-13 | 2014-04-09 | アイカジェン, インコーポレイテッド | ナトリウムチャネル阻害物質 |
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WO2009013171A2 (fr) | 2007-07-24 | 2009-01-29 | F. Hoffmann-La Roche Ag | Composés antiviraux hétérocycliques |
WO2009099177A1 (fr) | 2008-02-06 | 2009-08-13 | Taisho Pharmaceutical Co., Ltd. | Dérivé d'amino-imidazole |
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WO2010029300A1 (fr) | 2008-09-12 | 2010-03-18 | Biolipox Ab | Composés bis-aromatiques pour utilisation dans le traitement de l’inflammation |
PE20142099A1 (es) | 2009-01-12 | 2014-12-13 | Icagen Inc | Derivados de sulfonamida |
ES2533065T3 (es) | 2010-07-09 | 2015-04-07 | Pfizer Limited | Bencenosulfonamidas útiles como inhibidores de los canales de sodio |
RU2563644C2 (ru) | 2010-08-20 | 2015-09-20 | Хатчисон Медифарма Лимитед | Пирролопиримидиновые соединения и их применения |
CA2844799A1 (fr) | 2011-08-17 | 2013-02-21 | Amgen Inc. | Inhibiteurs de canal sodium heteroaryle |
BR112014010197A2 (pt) | 2011-10-28 | 2017-04-18 | Merck Sharp & Dohme | composto, composição farmacêutica, método de tratamento de um distúrbio |
US9481677B2 (en) | 2011-10-31 | 2016-11-01 | Xenon Pharmaceuticals Inc. | Biaryl ether sulfonamides and their use as therapeutic agents |
CA2853439A1 (fr) * | 2011-10-31 | 2013-05-10 | Xenon Pharmaceuticals Inc. | Composes de benzenesulfonamide et leur utilisation en tant qu'agents therapeutiques |
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WO2013122897A1 (fr) | 2012-02-13 | 2013-08-22 | Amgen Inc. | Inhibiteurs des canaux sodiques de type dihydrobenzoxazine et tétrahydroquinoxaline |
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EP3444249B1 (fr) | 2012-10-15 | 2020-05-13 | Daewoong Pharmaceutical Co., Ltd. | Bloqueurs de canal sodique, leur procédé de préparation et leur utilisation |
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BR112015009216A2 (pt) | 2012-10-26 | 2017-07-04 | Merck Sharp & Dohme | composto ou um sal farmaceuticamente aceitável do mesmo, composição farmacêutica, e, uso de uma composição farmacêutica |
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WO2015077905A1 (fr) | 2013-11-29 | 2015-06-04 | Merck Sharp & Dohme Corp. | Composés de benzènesulfonamide à substitution bicycloamine ayant une activité sélective dans les canaux sodiques sensibles à la tension |
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EP3484464B1 (fr) | 2016-03-22 | 2020-10-28 | Merck Sharp & Dohme Corp. | Composés de n1-phénylpropane-1,2-diamine ayant une activité sélective des canaux sodiques sensibles à la tension |
TN2018000385A1 (en) * | 2016-05-20 | 2020-06-15 | Xenon Pharmaceuticals Inc | Benzenesulfonamide compounds and their use as therapeutic agents |
CN110088093B (zh) | 2016-10-27 | 2023-06-13 | 百时美施贵宝公司 | 酰基磺酰胺NaV1.7抑制剂 |
EP3541373B1 (fr) * | 2016-11-17 | 2023-11-01 | Merck Sharp & Dohme LLC | Composés d'arylsulfonamide à liaisons diamino-alkylamino présentant une activité sélective dans les canaux sodiques sensibles à la tension |
BR112019011121A2 (pt) | 2016-12-09 | 2019-10-01 | Xenon Pharmaceuticals Inc | compostos de benzenossulfonamida e seu uso como agentes terapêuticos |
UA127024C2 (uk) | 2018-06-13 | 2023-03-15 | Ксенон Фармасьютікалз Інк. | Бензолсульфонамідні сполуки та їх застосування як терапевтичних агентів |
CN112638879B (zh) | 2018-08-31 | 2024-06-18 | 泽农医药公司 | 杂芳基取代的磺酰胺化合物及其作为治疗剂的用途 |
CN112638898B (zh) | 2018-08-31 | 2024-04-09 | 泽农医药公司 | 杂芳基取代的磺酰胺化合物及其作为钠通道抑制剂的用途 |
-
2019
- 2019-06-13 UA UAA202008102A patent/UA127024C2/uk unknown
- 2019-06-13 SG SG11202011862PA patent/SG11202011862PA/en unknown
- 2019-06-13 EA EA202092719A patent/EA202092719A1/ru unknown
- 2019-06-13 KR KR1020217000602A patent/KR20210019507A/ko not_active Application Discontinuation
- 2019-06-13 CA CA3103600A patent/CA3103600A1/fr active Pending
- 2019-06-13 CN CN201980039029.1A patent/CN112262142B/zh active Active
- 2019-06-13 CR CR20200613A patent/CR20200613A/es unknown
- 2019-06-13 JP JP2020568796A patent/JP7371029B2/ja active Active
- 2019-06-13 MX MX2020013317A patent/MX2020013317A/es unknown
- 2019-06-13 PE PE2020001990A patent/PE20211389A1/es unknown
- 2019-06-13 BR BR112020024729-4A patent/BR112020024729A2/pt unknown
- 2019-06-13 US US16/440,459 patent/US10745392B2/en active Active
- 2019-06-13 EP EP19735024.2A patent/EP3807281A1/fr active Pending
- 2019-06-13 MA MA052888A patent/MA52888A/fr unknown
- 2019-06-13 AU AU2019285184A patent/AU2019285184B2/en active Active
- 2019-06-13 WO PCT/US2019/037011 patent/WO2019241533A1/fr unknown
- 2019-06-13 IL IL278949A patent/IL278949B2/en unknown
- 2019-12-13 JO JOP/2020/0304A patent/JOP20200304A1/ar unknown
-
2020
- 2020-07-13 US US16/927,178 patent/US11325902B2/en active Active
- 2020-12-09 CL CL2020003197A patent/CL2020003197A1/es unknown
- 2020-12-09 PH PH12020552111A patent/PH12020552111A1/en unknown
- 2020-12-10 NI NI202000098A patent/NI202000098A/es unknown
- 2020-12-10 SA SA520420768A patent/SA520420768B1/ar unknown
- 2020-12-10 EC ECSENADI202079861A patent/ECSP20079861A/es unknown
-
2023
- 2023-08-08 JP JP2023129150A patent/JP2023138672A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
KR20210019507A (ko) | 2021-02-22 |
US11325902B2 (en) | 2022-05-10 |
IL278949B1 (en) | 2024-04-01 |
IL278949A (en) | 2021-01-31 |
US20200361927A1 (en) | 2020-11-19 |
NI202000098A (es) | 2021-05-28 |
UA127024C2 (uk) | 2023-03-15 |
IL278949B2 (en) | 2024-08-01 |
CR20200613A (es) | 2021-06-10 |
ECSP20079861A (es) | 2021-03-31 |
CN112262142A (zh) | 2021-01-22 |
EP3807281A1 (fr) | 2021-04-21 |
EA202092719A1 (ru) | 2021-03-16 |
CL2020003197A1 (es) | 2021-04-30 |
PH12020552111A1 (en) | 2021-08-02 |
MX2020013317A (es) | 2021-04-13 |
AU2019285184B2 (en) | 2023-11-16 |
JP2021528387A (ja) | 2021-10-21 |
JP7371029B2 (ja) | 2023-10-30 |
PE20211389A1 (es) | 2021-07-27 |
CN112262142B (zh) | 2023-11-14 |
AU2019285184A1 (en) | 2021-01-28 |
JOP20200304A1 (ar) | 2020-11-25 |
SA520420768B1 (ar) | 2022-08-30 |
SG11202011862PA (en) | 2020-12-30 |
US20190382398A1 (en) | 2019-12-19 |
US10745392B2 (en) | 2020-08-18 |
JP2023138672A (ja) | 2023-10-02 |
CA3103600A1 (fr) | 2019-12-19 |
WO2019241533A1 (fr) | 2019-12-19 |
BR112020024729A2 (pt) | 2021-03-23 |
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