MA56183A - Pyrazolo-pyridines hétéroaromatiques substituées et leur utilisation en tant que modulateurs du récepteur glun2b - Google Patents
Pyrazolo-pyridines hétéroaromatiques substituées et leur utilisation en tant que modulateurs du récepteur glun2bInfo
- Publication number
- MA56183A MA56183A MA056183A MA56183A MA56183A MA 56183 A MA56183 A MA 56183A MA 056183 A MA056183 A MA 056183A MA 56183 A MA56183 A MA 56183A MA 56183 A MA56183 A MA 56183A
- Authority
- MA
- Morocco
- Prior art keywords
- pyrazolo
- pyridines
- receptor modulators
- substituted heteroaromatic
- glun2b receptor
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/444—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/4965—Non-condensed pyrazines
- A61K31/497—Non-condensed pyrazines containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Epidemiology (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201962861665P | 2019-06-14 | 2019-06-14 | |
PK34920 | 2020-06-03 |
Publications (1)
Publication Number | Publication Date |
---|---|
MA56183A true MA56183A (fr) | 2022-04-20 |
Family
ID=73781827
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MA056183A MA56183A (fr) | 2019-06-14 | 2020-06-12 | Pyrazolo-pyridines hétéroaromatiques substituées et leur utilisation en tant que modulateurs du récepteur glun2b |
Country Status (21)
Country | Link |
---|---|
US (2) | US11530210B2 (fr) |
EP (1) | EP3982958A1 (fr) |
JP (1) | JP2022536424A (fr) |
KR (1) | KR20220024512A (fr) |
CN (1) | CN114007610A (fr) |
AU (1) | AU2020291188A1 (fr) |
BR (1) | BR112021025141A2 (fr) |
CA (1) | CA3143276A1 (fr) |
CL (1) | CL2021003257A1 (fr) |
CO (1) | CO2021016860A2 (fr) |
CR (1) | CR20210615A (fr) |
DO (1) | DOP2021000250A (fr) |
EC (1) | ECSP21090450A (fr) |
IL (1) | IL288858A (fr) |
JO (1) | JOP20210330A1 (fr) |
MA (1) | MA56183A (fr) |
MX (1) | MX2021015503A (fr) |
PE (1) | PE20220806A1 (fr) |
SG (1) | SG11202112405VA (fr) |
TW (1) | TW202115054A (fr) |
WO (1) | WO2020249785A1 (fr) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
TW201819376A (zh) | 2016-10-06 | 2018-06-01 | 比利時商健生藥品公司 | 經取代之1H-咪唑並[4,5-b]吡啶-2(3H)-酮及其作為GLUN2B受體調節劑之用途 |
WO2020249802A1 (fr) | 2019-06-14 | 2020-12-17 | Janssen Pharmaceutica Nv | Pyrazolo-pyrazines substituées et leur utilisation en tant que modulateurs du récepteur de glun2b |
AU2020290772A1 (en) | 2019-06-14 | 2022-01-06 | Janssen Pharmaceutica Nv | Pyrazine carbamates and their use as GluN2B receptor modulators |
JP2022538774A (ja) | 2019-06-14 | 2022-09-06 | ヤンセン ファーマシューティカ エヌ.ベー. | ピリジンカルバメート及びglun2b受容体調節因子としてのそれらの使用 |
CA3143102A1 (fr) | 2019-06-14 | 2020-12-17 | Janssen Pharmaceutica Nv | Pyrazolo[4,3-b]pyridines substituees et leur utilisation en tant que modulateurs du recepteur glun2b |
CA3142996A1 (fr) | 2019-06-14 | 2020-12-17 | Janssen Pharmaceutica Nv | Pyrazolo-pyridine amides substitues et leur utilisation en tant que modulateurs du recepteur glun2b |
MX2021015503A (es) | 2019-06-14 | 2022-04-20 | Janssen Pharmaceutica Nv | Pirazolo piridinas heteroaromáticas sustituidas y su uso como moduladores del receptor glun2b. |
CN114149425A (zh) * | 2021-11-16 | 2022-03-08 | 上海应用技术大学 | 5-氟甲基吡啶衍生物和18-f同位素标记的5-氟甲基吡啶衍生物及其制备与应用 |
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GB9407447D0 (en) | 1994-04-14 | 1994-06-08 | Glaxo Group Ltd | Chemical compounds |
CA2262502C (fr) | 1996-07-31 | 2002-11-26 | Nikken Chemicals Co., Ltd. | Derives de 6-phenyltetrahydro-1,3-oxazine-2-one et compositions medicinales a base de ces composes |
EP1296958A4 (fr) | 2000-06-26 | 2004-01-28 | Merck & Co Inc | Antagonistes des recepteurs nmda nr2b de l'iminopyrimidine |
US6610723B2 (en) | 2001-01-29 | 2003-08-26 | Hoffmann-La Roche Inc. | Imidazole derivatives |
IL159768A0 (en) | 2001-07-24 | 2004-06-20 | Genset Sa | Polynucleotides encoding glycine transporter polypeptides, their preparation and use |
CA2480317A1 (fr) | 2002-03-28 | 2003-10-09 | Eisai Co., Ltd. | 7-azaindoles en tant qu'inhibiteurs de kinases a terminaison c-jun n pour le traitement de troubles neurodegeneratifs |
US7005432B2 (en) | 2002-05-16 | 2006-02-28 | Hoffman-La Roche Inc. | Substituted imidazol-pyridazine derivatives |
WO2005080379A1 (fr) | 2004-02-18 | 2005-09-01 | Astrazeneca Ab | Composes de triazole et leur utilisation en tant qu'antagonistes du recepteur metabotrope du glutamate |
RU2007110731A (ru) | 2004-09-23 | 2008-10-27 | Редди Юс Терапевтикс | Новые соединения пиримидина, способ их получения и содержащие их композиции |
WO2007115231A2 (fr) | 2006-03-30 | 2007-10-11 | Chemocentryx, Inc. | Modulateurs de cxcr4 |
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WO2009004430A1 (fr) | 2007-06-29 | 2009-01-08 | Pfizer Inc. | N-benzyl oxazolidinones et composés hétérocycliques apparentés comme potentialisateurs de récepteurs du glutamate |
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CA2719749A1 (fr) | 2008-03-27 | 2009-10-01 | Evotec Neurosciences Gmbh | Procedes pour traiter des troubles utilisant un antagoniste selectif de sous-type nr2b de nmda |
WO2009157196A1 (fr) | 2008-06-25 | 2009-12-30 | 武田薬品工業株式会社 | Composé amide |
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DK2669270T3 (en) | 2011-01-28 | 2018-02-26 | Sato Pharma | Indole-related compounds such as URAT1 inhibitors |
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HUE026072T2 (en) | 2011-09-19 | 2016-05-30 | Sanofi Sa | N- [4- (1H-pyrazolo [3,4-B] pyrazin-6-yl) phenyl] sulfonamides and their use as medicaments |
WO2013060029A1 (fr) | 2011-10-28 | 2013-05-02 | Merck Sharp & Dohme Corp | Modulateurs allostériques des récepteurs métabotropiques du glutamate |
WO2013130855A1 (fr) | 2012-03-02 | 2013-09-06 | Takeda Pharmaceutical Company Limited | Dérivés d'indazole |
MA37975B2 (fr) | 2012-09-11 | 2021-03-31 | Genzyme Corp | Inhibiteurs de synthase de glucosylcéramide |
WO2014124651A1 (fr) | 2013-02-15 | 2014-08-21 | Københavns Universitet | Dérivés de pyrrolidine-2-acide carboxylique utilisés en tant qu'antagonistes de iglur |
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MA41803A (fr) | 2015-03-24 | 2018-01-30 | Almirall Sa | Dérivés amino-indazoles utilisés comme inhibiteurs des canaux sodiques |
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CN108026094B (zh) | 2015-07-09 | 2021-02-09 | 詹森药业有限公司 | 取代的4-氮杂吲哚以及它们作为glun2b受体调节剂的用途 |
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TW201819376A (zh) * | 2016-10-06 | 2018-06-01 | 比利時商健生藥品公司 | 經取代之1H-咪唑並[4,5-b]吡啶-2(3H)-酮及其作為GLUN2B受體調節劑之用途 |
CN110831593A (zh) | 2017-06-14 | 2020-02-21 | 特维娜有限公司 | 用于调节s1p1活性的化合物及其使用方法 |
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WO2019193516A2 (fr) | 2018-04-04 | 2019-10-10 | Janssen Pharmaceutica Nv | Pyridine et pyrimidines substituées et leur utilisation en tant que modulateurs du récepteur glun2b |
CN110294756A (zh) | 2019-06-04 | 2019-10-01 | 广州市原子高科同位素医药有限公司 | GluN2B亚基靶向型中枢神经系统正电子示踪剂及其制备 |
CA3143102A1 (fr) | 2019-06-14 | 2020-12-17 | Janssen Pharmaceutica Nv | Pyrazolo[4,3-b]pyridines substituees et leur utilisation en tant que modulateurs du recepteur glun2b |
CA3142996A1 (fr) | 2019-06-14 | 2020-12-17 | Janssen Pharmaceutica Nv | Pyrazolo-pyridine amides substitues et leur utilisation en tant que modulateurs du recepteur glun2b |
WO2020249802A1 (fr) | 2019-06-14 | 2020-12-17 | Janssen Pharmaceutica Nv | Pyrazolo-pyrazines substituées et leur utilisation en tant que modulateurs du récepteur de glun2b |
AU2020290772A1 (en) | 2019-06-14 | 2022-01-06 | Janssen Pharmaceutica Nv | Pyrazine carbamates and their use as GluN2B receptor modulators |
JP2022538774A (ja) | 2019-06-14 | 2022-09-06 | ヤンセン ファーマシューティカ エヌ.ベー. | ピリジンカルバメート及びglun2b受容体調節因子としてのそれらの使用 |
MX2021015503A (es) * | 2019-06-14 | 2022-04-20 | Janssen Pharmaceutica Nv | Pirazolo piridinas heteroaromáticas sustituidas y su uso como moduladores del receptor glun2b. |
-
2020
- 2020-06-12 MX MX2021015503A patent/MX2021015503A/es unknown
- 2020-06-12 SG SG11202112405VA patent/SG11202112405VA/en unknown
- 2020-06-12 CR CR20210615A patent/CR20210615A/es unknown
- 2020-06-12 KR KR1020227001097A patent/KR20220024512A/ko unknown
- 2020-06-12 BR BR112021025141A patent/BR112021025141A2/pt unknown
- 2020-06-12 US US16/899,829 patent/US11530210B2/en active Active
- 2020-06-12 AU AU2020291188A patent/AU2020291188A1/en active Pending
- 2020-06-12 PE PE2021002072A patent/PE20220806A1/es unknown
- 2020-06-12 JP JP2021573899A patent/JP2022536424A/ja active Pending
- 2020-06-12 EP EP20733713.0A patent/EP3982958A1/fr active Pending
- 2020-06-12 WO PCT/EP2020/066384 patent/WO2020249785A1/fr unknown
- 2020-06-12 TW TW109119836A patent/TW202115054A/zh unknown
- 2020-06-12 JO JOP/2021/0330A patent/JOP20210330A1/ar unknown
- 2020-06-12 CA CA3143276A patent/CA3143276A1/fr active Pending
- 2020-06-12 MA MA056183A patent/MA56183A/fr unknown
- 2020-06-12 CN CN202080043611.8A patent/CN114007610A/zh active Pending
-
2021
- 2021-12-02 DO DO2021000250A patent/DOP2021000250A/es unknown
- 2021-12-07 CL CL2021003257A patent/CL2021003257A1/es unknown
- 2021-12-09 IL IL288858A patent/IL288858A/en unknown
- 2021-12-13 CO CONC2021/0016860A patent/CO2021016860A2/es unknown
- 2021-12-14 EC ECSENADI202190450A patent/ECSP21090450A/es unknown
-
2022
- 2022-09-12 US US17/942,829 patent/US20230045960A1/en active Pending
Also Published As
Publication number | Publication date |
---|---|
AU2020291188A1 (en) | 2022-01-20 |
EP3982958A1 (fr) | 2022-04-20 |
US20230045960A1 (en) | 2023-02-16 |
JP2022536424A (ja) | 2022-08-16 |
CA3143276A1 (fr) | 2020-12-17 |
US11530210B2 (en) | 2022-12-20 |
BR112021025141A2 (pt) | 2022-01-25 |
CO2021016860A2 (es) | 2022-01-17 |
TW202115054A (zh) | 2021-04-16 |
SG11202112405VA (en) | 2021-12-30 |
ECSP21090450A (es) | 2022-01-31 |
PE20220806A1 (es) | 2022-05-20 |
DOP2021000250A (es) | 2022-03-31 |
WO2020249785A1 (fr) | 2020-12-17 |
CR20210615A (es) | 2022-01-31 |
IL288858A (en) | 2022-02-01 |
CN114007610A (zh) | 2022-02-01 |
JOP20210330A1 (ar) | 2023-01-30 |
MX2021015503A (es) | 2022-04-20 |
US20210017169A1 (en) | 2021-01-21 |
CL2021003257A1 (es) | 2022-08-19 |
KR20220024512A (ko) | 2022-03-03 |
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