MA51417A - Constructions d'anticorps bispécifiques dirigés contre muc17 et cd3 - Google Patents
Constructions d'anticorps bispécifiques dirigés contre muc17 et cd3Info
- Publication number
- MA51417A MA51417A MA051417A MA51417A MA51417A MA 51417 A MA51417 A MA 51417A MA 051417 A MA051417 A MA 051417A MA 51417 A MA51417 A MA 51417A MA 51417 A MA51417 A MA 51417A
- Authority
- MA
- Morocco
- Prior art keywords
- constructions
- directed against
- bispecific antibodies
- antibodies directed
- muc17
- Prior art date
Links
- 101000623904 Homo sapiens Mucin-17 Proteins 0.000 title 1
- 102100023125 Mucin-17 Human genes 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
- C07K16/2809—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against the T-cell receptor (TcR)-CD3 complex
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
- C07K16/3076—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells against structure-related tumour-associated moieties
- C07K16/3092—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells against structure-related tumour-associated moieties against tumour-associated mucins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
- A61K2039/572—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2 cytotoxic response
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/31—Immunoglobulins specific features characterized by aspects of specificity or valency multispecific
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/33—Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/52—Constant or Fc region; Isotype
- C07K2317/524—CH2 domain
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/52—Constant or Fc region; Isotype
- C07K2317/526—CH3 domain
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/52—Constant or Fc region; Isotype
- C07K2317/53—Hinge
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
- C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
- C07K2317/622—Single chain antibody (scFv)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Cell Biology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201762612242P | 2017-12-29 | 2017-12-29 | |
US201862687063P | 2018-06-19 | 2018-06-19 |
Publications (1)
Publication Number | Publication Date |
---|---|
MA51417A true MA51417A (fr) | 2020-11-04 |
Family
ID=65139282
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MA051417A MA51417A (fr) | 2017-12-29 | 2018-12-31 | Constructions d'anticorps bispécifiques dirigés contre muc17 et cd3 |
Country Status (21)
Country | Link |
---|---|
US (1) | US20210130465A1 (fr) |
EP (1) | EP3732200A1 (fr) |
JP (2) | JP2021508465A (fr) |
KR (1) | KR20200105493A (fr) |
CN (2) | CN111630067B (fr) |
AU (1) | AU2018394255A1 (fr) |
CA (1) | CA3087151A1 (fr) |
CL (1) | CL2020001732A1 (fr) |
CO (1) | CO2020009034A2 (fr) |
CR (1) | CR20200325A (fr) |
IL (1) | IL275492A (fr) |
JO (1) | JOP20200158A1 (fr) |
MA (1) | MA51417A (fr) |
MX (1) | MX2020006871A (fr) |
PE (1) | PE20201340A1 (fr) |
PH (1) | PH12020550841A1 (fr) |
SG (1) | SG11202005274VA (fr) |
TW (1) | TW201940518A (fr) |
UA (1) | UA128330C2 (fr) |
UY (1) | UY38041A (fr) |
WO (1) | WO2019133961A1 (fr) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN116096751A (zh) * | 2020-02-25 | 2023-05-09 | 璟尚生物制药公司 | 三特异性t细胞接合器 |
CN115551895A (zh) * | 2020-03-05 | 2022-12-30 | 纪念斯隆凯特琳癌症中心 | 抗ccr8剂 |
CA3175275A1 (fr) | 2020-03-19 | 2021-09-23 | Amgen Inc. | Anticorps contre la mucine 17 et leurs utilisations |
MX2023003041A (es) | 2020-09-16 | 2023-05-09 | Amgen Inc | Métodos para administrar dosis terapéuticas de moléculas de acoplamiento a células t biespecíficas para el tratamiento de cáncer. |
JP2024525482A (ja) * | 2021-06-30 | 2024-07-12 | アムジェン インコーポレイテッド | 凍結乾燥処方物を再構成する方法 |
WO2023088287A1 (fr) * | 2021-11-17 | 2023-05-25 | Acroimmune Guangzhou Biotech Ltd | Protéines de fusion comprenant un peptide noyau ai-073 et leur utilisation |
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2018
- 2018-12-28 TW TW107147698A patent/TW201940518A/zh unknown
- 2018-12-28 UY UY0001038041A patent/UY38041A/es unknown
- 2018-12-31 EP EP18837141.3A patent/EP3732200A1/fr active Pending
- 2018-12-31 AU AU2018394255A patent/AU2018394255A1/en active Pending
- 2018-12-31 PE PE2020000859A patent/PE20201340A1/es unknown
- 2018-12-31 JP JP2020535956A patent/JP2021508465A/ja active Pending
- 2018-12-31 SG SG11202005274VA patent/SG11202005274VA/en unknown
- 2018-12-31 JO JOP/2020/0158A patent/JOP20200158A1/ar unknown
- 2018-12-31 CR CR20200325A patent/CR20200325A/es unknown
- 2018-12-31 WO PCT/US2018/068118 patent/WO2019133961A1/fr active Application Filing
- 2018-12-31 CN CN201880076187.XA patent/CN111630067B/zh active Active
- 2018-12-31 US US16/956,797 patent/US20210130465A1/en active Pending
- 2018-12-31 CN CN202311579367.9A patent/CN117510645A/zh active Pending
- 2018-12-31 KR KR1020207021768A patent/KR20200105493A/ko not_active Application Discontinuation
- 2018-12-31 MA MA051417A patent/MA51417A/fr unknown
- 2018-12-31 CA CA3087151A patent/CA3087151A1/fr active Pending
- 2018-12-31 MX MX2020006871A patent/MX2020006871A/es unknown
- 2018-12-31 UA UAA202004810A patent/UA128330C2/uk unknown
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2020
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IL275492A (en) | 2020-08-31 |
PE20201340A1 (es) | 2020-11-25 |
PH12020550841A1 (en) | 2021-05-17 |
UY38041A (es) | 2019-06-28 |
SG11202005274VA (en) | 2020-07-29 |
CO2020009034A2 (es) | 2020-07-31 |
CN117510645A (zh) | 2024-02-06 |
MX2020006871A (es) | 2020-08-24 |
EP3732200A1 (fr) | 2020-11-04 |
US20210130465A1 (en) | 2021-05-06 |
CN111630067B (zh) | 2023-12-05 |
CA3087151A1 (fr) | 2019-07-04 |
CR20200325A (es) | 2020-11-09 |
AU2018394255A1 (en) | 2020-06-11 |
WO2019133961A1 (fr) | 2019-07-04 |
JP2023134497A (ja) | 2023-09-27 |
TW201940518A (zh) | 2019-10-16 |
UA128330C2 (uk) | 2024-06-12 |
JOP20200158A1 (ar) | 2022-10-30 |
KR20200105493A (ko) | 2020-09-07 |
CL2020001732A1 (es) | 2021-02-12 |
CN111630067A (zh) | 2020-09-04 |
BR112020013018A2 (pt) | 2021-02-17 |
JP2021508465A (ja) | 2021-03-11 |
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