MA47606A - Procédés de purification d'arn messager - Google Patents

Procédés de purification d'arn messager

Info

Publication number
MA47606A
MA47606A MA047606A MA47606A MA47606A MA 47606 A MA47606 A MA 47606A MA 047606 A MA047606 A MA 047606A MA 47606 A MA47606 A MA 47606A MA 47606 A MA47606 A MA 47606A
Authority
MA
Morocco
Prior art keywords
messenger rna
purification processes
rna purification
processes
messenger
Prior art date
Application number
MA047606A
Other languages
English (en)
Inventor
Jonathan Abysalh
Daniel Crawford
Frank Derosa
Anusha Dias
Michael Heartlein
Shrirang Karve
Original Assignee
Translate Bio Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Translate Bio Inc filed Critical Translate Bio Inc
Publication of MA47606A publication Critical patent/MA47606A/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1003—Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1003—Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor
    • C12N15/1006—Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor by means of a solid support carrier, e.g. particles, polymers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C07H21/04—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with deoxyribosyl as saccharide radical
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1003—Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor
    • C12N15/1017—Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor by filtration, e.g. using filters, frits, membranes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034—Isolating an individual clone by screening libraries
    • C12N15/1065—Preparation or screening of tagged libraries, e.g. tagged microorganisms by STM-mutagenesis, tagged polynucleotides, gene tags
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/10—Type of nucleic acid
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y201/00—Transferases transferring one-carbon groups (2.1)
    • C12Y201/03—Carboxy- and carbamoyltransferases (2.1.3)
    • C12Y201/03003—Ornithine carbamoyltransferase (2.1.3.3)
MA047606A 2017-02-27 2018-02-27 Procédés de purification d'arn messager MA47606A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201762463981P 2017-02-27 2017-02-27

Publications (1)

Publication Number Publication Date
MA47606A true MA47606A (fr) 2021-04-07

Family

ID=61683899

Family Applications (1)

Application Number Title Priority Date Filing Date
MA047606A MA47606A (fr) 2017-02-27 2018-02-27 Procédés de purification d'arn messager

Country Status (10)

Country Link
US (2) US10975369B2 (fr)
EP (2) EP3585892B8 (fr)
AU (1) AU2018224318A1 (fr)
CA (1) CA3054323A1 (fr)
DK (1) DK3585892T3 (fr)
ES (1) ES2925083T3 (fr)
HU (1) HUE059594T2 (fr)
IL (1) IL268856A (fr)
MA (1) MA47606A (fr)
WO (1) WO2018157141A1 (fr)

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CN115443338A (zh) 2020-02-10 2022-12-06 翻译生物公司 用于信使rna纯化的方法和组合物
JP2023514450A (ja) 2020-02-25 2023-04-05 トランスレイト バイオ， インコーポレイテッド Ｍｒｎａ担持脂質ナノ粒子を調製する改善された方法
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WO2022081548A1 (fr) 2020-10-12 2022-04-21 Translate Bio, Inc. Procédé amélioré de préparation de nanoparticules lipidiques à base de glace
JP2023545128A (ja) 2020-10-12 2023-10-26 トランスレイト バイオ， インコーポレイテッド ｍＲＮＡ搭載脂質ナノ粒子を製造する改善された方法
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EP4313115A1 (fr) 2021-03-25 2024-02-07 Translate Bio, Inc. Séquences nucléotidiques optimisées codant pour le domaine extracellulaire de la protéine ace2 humaine ou une portion de celle-ci
EP4326338A1 (fr) 2021-04-19 2024-02-28 Translate Bio, Inc. Compositions améliorées pour l'administration d'arnm
KR20240021170A (ko) 2021-05-12 2024-02-16 더 브로드 인스티튜트, 인코퍼레이티드 변형된 mRNA, 변형된 비-코딩 RNA, 및 그의 용도
WO2023278754A1 (fr) 2021-07-01 2023-01-05 Translate Bio, Inc. Compositions de livraison d'arnm
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BE1030203B1 (fr) * 2022-01-20 2023-08-21 Quantoom Biosciences S A Méthodes et systèmes de coiffage de molécules d’acide nucléique
WO2023118572A1 (fr) * 2021-12-23 2023-06-29 Quantoom Biosciences S.A. Procédés et systèmes de coiffage de molécules d'acides nucléiques
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US10975369B2 (en) 2021-04-13
EP3585892A1 (fr) 2020-01-01
US20210180041A1 (en) 2021-06-17
WO2018157141A1 (fr) 2018-08-30
AU2018224318A1 (en) 2019-09-19
EP4008783A1 (fr) 2022-06-08
ES2925083T3 (es) 2022-10-13
HUE059594T2 (hu) 2022-11-28
US20180251754A1 (en) 2018-09-06
IL268856A (en) 2019-10-31
CA3054323A1 (fr) 2018-08-30
EP3585892B8 (fr) 2022-07-13
EP3585892B1 (fr) 2022-06-01
DK3585892T3 (da) 2022-08-22

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