MA47605A - Procédés de purification d'arn messager - Google Patents
Procédés de purification d'arn messagerInfo
- Publication number
- MA47605A MA47605A MA047605A MA47605A MA47605A MA 47605 A MA47605 A MA 47605A MA 047605 A MA047605 A MA 047605A MA 47605 A MA47605 A MA 47605A MA 47605 A MA47605 A MA 47605A
- Authority
- MA
- Morocco
- Prior art keywords
- messenger rna
- purification processes
- rna purification
- processes
- messenger
- Prior art date
Links
- 238000000746 purification Methods 0.000 title 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1003—Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor
- C12N15/1017—Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor by filtration, e.g. using filters, frits, membranes
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/502753—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by bulk separation arrangements on lab-on-a-chip devices, e.g. for filtration or centrifugation
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6806—Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/02—Adapting objects or devices to another
- B01L2200/028—Modular arrangements
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/16—Reagents, handling or storing thereof
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/06—Auxiliary integrated devices, integrated components
- B01L2300/0681—Filter
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/04—Moving fluids with specific forces or mechanical means
- B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
- B01L2400/0409—Moving fluids with specific forces or mechanical means specific forces centrifugal forces
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2523/00—Reactions characterised by treatment of reaction samples
- C12Q2523/10—Characterised by chemical treatment
- C12Q2523/113—Denaturating agents
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2523/00—Reactions characterised by treatment of reaction samples
- C12Q2523/30—Characterised by physical treatment
- C12Q2523/308—Adsorption or desorption
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y201/00—Transferases transferring one-carbon groups (2.1)
- C12Y201/03—Carboxy- and carbamoyltransferases (2.1.3)
- C12Y201/03003—Ornithine carbamoyltransferase (2.1.3.3)
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Analytical Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Crystallography & Structural Chemistry (AREA)
- Plant Pathology (AREA)
- Immunology (AREA)
- Dispersion Chemistry (AREA)
- Hematology (AREA)
- Clinical Laboratory Science (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762463998P | 2017-02-27 | 2017-02-27 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MA47605A true MA47605A (fr) | 2020-01-01 |
Family
ID=61628474
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MA047605A MA47605A (fr) | 2017-02-27 | 2018-02-27 | Procédés de purification d'arn messager |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US10808241B2 (fr) |
| EP (2) | EP3971291A1 (fr) |
| AU (1) | AU2018224843A1 (fr) |
| CA (1) | CA3054321A1 (fr) |
| CY (1) | CY1124735T1 (fr) |
| DK (1) | DK3585891T3 (fr) |
| ES (1) | ES2899323T3 (fr) |
| HU (1) | HUE059025T2 (fr) |
| IL (1) | IL268857B1 (fr) |
| MA (1) | MA47605A (fr) |
| WO (1) | WO2018157133A1 (fr) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2012267578B2 (en) | 2011-06-08 | 2017-04-20 | Translate Bio, Inc. | Cleavable lipids |
| EP2970955B1 (fr) | 2013-03-14 | 2018-11-14 | Translate Bio, Inc. | Procédés de purification d'arn messager |
| MA47605A (fr) * | 2017-02-27 | 2020-01-01 | Translate Bio Inc | Procédés de purification d'arn messager |
| EP3714048A1 (fr) | 2017-11-22 | 2020-09-30 | Modernatx, Inc. | Polynucléotides codant pour l'ornithine transcarbamylase pour le traitement de troubles du cycle de l'urée |
| CA3097912A1 (fr) * | 2018-05-15 | 2019-11-21 | Translate Bio, Inc. | Administration sous-cutanee d'arn messager |
| CN112930396B (zh) | 2018-08-24 | 2024-05-24 | 川斯勒佰尔公司 | 用于纯化信使rna的方法 |
| US20210388338A1 (en) * | 2018-11-08 | 2021-12-16 | Translate Bio, Inc. | Methods and Compositions for Messenger RNA Purification |
| CN113396219A (zh) | 2019-02-11 | 2021-09-14 | 埃泽瑞斯公司 | 通过切向流过滤纯化mRNA |
| CN114127283A (zh) * | 2019-05-15 | 2022-03-01 | 川斯勒佰尔公司 | 用于纯化信使rna的方法 |
| CN115515559A (zh) | 2019-12-20 | 2022-12-23 | 翻译生物公司 | 信使rna的直肠递送 |
| WO2021127641A1 (fr) | 2019-12-20 | 2021-06-24 | Translate Bio, Inc. | Procédé amélioré de préparation de nanoparticules lipidiques chargées d'arnm |
| WO2021163134A1 (fr) | 2020-02-10 | 2021-08-19 | Translate Bio, Inc. | Procédés et compositions pour purification d'arn messager |
| WO2021173840A1 (fr) | 2020-02-25 | 2021-09-02 | Translate Bio, Inc. | Procédés améliorés de préparation de nanoparticules lipidiques chargées d'arnm |
| CA3177940A1 (fr) | 2020-05-07 | 2021-11-11 | Anusha DIAS | Sequences nucleotidiques optimisees codant pour des antigenes du sras-cov-2 |
| US20230190954A1 (en) | 2020-05-07 | 2023-06-22 | Translate Bio, Inc. | Composition and methods for treatment of primary ciliary dyskinesia |
| JP2023526284A (ja) | 2020-05-15 | 2023-06-21 | トランスレイト バイオ， インコーポレイテッド | ｍＲＮＡ送達のための脂質ナノ粒子製剤 |
| CA3197638A1 (fr) * | 2020-10-01 | 2022-04-07 | Translate Bio, Inc. | Procedes de purification d'arn messager |
| CA3194863A1 (fr) | 2020-10-06 | 2022-04-14 | Shrirang KARVE | Procede ameliore et formulation de nanoparticules lipidiques |
| US20220133631A1 (en) | 2020-10-12 | 2022-05-05 | Translate Bio, Inc. | Process of preparing ice-based lipid nanoparticles |
| KR20230087536A (ko) | 2020-10-12 | 2023-06-16 | 트랜슬레이트 바이오 인코포레이티드 | Mrna-로딩된 지질 나노입자를 제조하는 개선된 프로세스 |
| WO2022204549A1 (fr) | 2021-03-25 | 2022-09-29 | Translate Bio, Inc. | Séquences nucléotidiques optimisées codant pour le domaine extracellulaire de la protéine ace2 humaine ou une portion de celle-ci |
| JP2024515668A (ja) | 2021-04-19 | 2024-04-10 | トランスレイト バイオ， インコーポレイテッド | Ｍｒｎａの送達のための改善された組成物 |
| WO2023278754A1 (fr) | 2021-07-01 | 2023-01-05 | Translate Bio, Inc. | Compositions de livraison d'arnm |
| WO2023086893A1 (fr) | 2021-11-10 | 2023-05-19 | Translate Bio, Inc. | Composition et méthodes de traitement de la dyskinésie ciliaire primitive |
| WO2024083345A1 (fr) | 2022-10-21 | 2024-04-25 | BioNTech SE | Procédés et utilisations associés à des compositions liquides |
| WO2024112652A1 (fr) | 2022-11-21 | 2024-05-30 | Translate Bio, Inc. | Compositions de formulations de poudre sèche d'arn messager et leurs procédés d'utilisation |
| WO2024126809A1 (fr) | 2022-12-15 | 2024-06-20 | Sanofi | Arnm codant pour une particule de type virus de la grippe |
| WO2024133515A1 (fr) | 2022-12-20 | 2024-06-27 | Sanofi | Vaccin contre l'arnm de rhinovirus |
| WO2024133884A2 (fr) | 2022-12-23 | 2024-06-27 | Sanofi | Queue optimisée d'arn messager |
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| US4458066A (en) | 1980-02-29 | 1984-07-03 | University Patents, Inc. | Process for preparing polynucleotides |
| US5132418A (en) | 1980-02-29 | 1992-07-21 | University Patents, Inc. | Process for preparing polynucleotides |
| US4500707A (en) | 1980-02-29 | 1985-02-19 | University Patents, Inc. | Nucleosides useful in the preparation of polynucleotides |
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| US4973679A (en) | 1981-03-27 | 1990-11-27 | University Patents, Inc. | Process for oligonucleo tide synthesis using phosphormidite intermediates |
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| DE10131107A1 (de) | 2001-06-27 | 2003-01-09 | Mann & Hummel Filter | Filtervorrichtung bzw. schwenkbares Filtermedium für diese Filtervorrichtung |
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| JP6087504B2 (ja) | 2008-11-07 | 2017-03-01 | マサチューセッツ インスティテュート オブ テクノロジー | アミノアルコールリピドイドおよびその使用 |
| US20130059008A1 (en) | 2009-01-23 | 2013-03-07 | Jeffrey L. Atkinson | Drying methods for tuning microparticle properties |
| WO2011031566A1 (fr) | 2009-08-27 | 2011-03-17 | Newlight Technologies, Llc | Procédé de fabrication de polyhydroxyalcanoates |
| US8326547B2 (en) | 2009-10-07 | 2012-12-04 | Nanjingjinsirui Science & Technology Biology Corp. | Method of sequence optimization for improved recombinant protein expression using a particle swarm optimization algorithm |
| NZ700688A (en) | 2009-12-01 | 2016-02-26 | Shire Human Genetic Therapies | Delivery of mrna for the augmentation of proteins and enzymes in human genetic diseases |
| US8853377B2 (en) | 2010-11-30 | 2014-10-07 | Shire Human Genetic Therapies, Inc. | mRNA for use in treatment of human genetic diseases |
| AU2012267578B2 (en) | 2011-06-08 | 2017-04-20 | Translate Bio, Inc. | Cleavable lipids |
| JP6184945B2 (ja) | 2011-06-08 | 2017-08-23 | シャイアー ヒューマン ジェネティック セラピーズ インコーポレイテッド | ｍＲＮＡ送達のための脂質ナノ粒子組成物および方法 |
| JP6072788B2 (ja) * | 2011-07-25 | 2017-02-01 | サンガモ バイオサイエンシーズ， インコーポレイテッド | 嚢胞性線維症膜コンダクタンス制御因子（ｃｆｔｒ）遺伝子を改変するための方法および組成物 |
| AU2012328570B2 (en) | 2011-10-27 | 2017-08-31 | Massachusetts Institute Of Technology | Amino acid derivatives functionalized on the n-terminus capable of forming drug encapsulating microspheres and uses thereof |
| BR112014024131A2 (pt) | 2012-03-29 | 2017-07-25 | Shire Human Genetic Therapies | lipídios catiônicos ionizáveis |
| US9877919B2 (en) | 2012-03-29 | 2018-01-30 | Translate Bio, Inc. | Lipid-derived neutral nanoparticles |
| EP3536787A1 (fr) | 2012-06-08 | 2019-09-11 | Translate Bio, Inc. | Polynucléotides résistant aux nucléases et leurs utilisations |
| EA201492055A1 (ru) | 2012-06-08 | 2015-11-30 | Шир Хьюман Дженетик Терапис, Инк. | ИНГАЛЯЦИОННАЯ ДОСТАВКА мРНК В НЕЛЕГОЧНЫЕ КЛЕТКИ-МИШЕНИ |
| EP2929035A1 (fr) | 2012-12-07 | 2015-10-14 | Shire Human Genetic Therapies, Inc. | Nanoparticules lipidiques pour administration de marn |
| EA037922B1 (ru) | 2013-03-14 | 2021-06-07 | Шир Хьюман Дженетик Терапис, Инк. | мРНК CFTR И КОМПОЗИЦИИ ДЛЯ ЛЕЧЕНИЯ МУКОВИСЦИДОЗА У МЛЕКОПИТАЮЩЕГО |
| EP2970955B1 (fr) | 2013-03-14 | 2018-11-14 | Translate Bio, Inc. | Procédés de purification d'arn messager |
| ES2647832T3 (es) | 2013-03-14 | 2017-12-26 | Translate Bio, Inc. | Ácidos ribonucleicos con nucleótidos modificados con 4-tio y procedimientos relacionados |
| HUE055044T2 (hu) | 2013-03-14 | 2021-10-28 | Translate Bio Inc | MRNS-kódolt ellenanyagok bejuttatására szolgáló eljárások és készítmények |
| CN105209633A (zh) | 2013-03-14 | 2015-12-30 | 夏尔人类遗传性治疗公司 | 信使rna加帽效率的定量评估 |
| ES2680595T3 (es) | 2013-03-14 | 2018-09-10 | Translate Bio, Inc. | Evaluación cuantitativa para eficacia de ARN mensajero para tapar |
| EP3431592A1 (fr) | 2013-03-14 | 2019-01-23 | Translate Bio, Inc. | Compositions thérapeutiques d'arnm et utilisation dans le traitement de maladies et de troubles |
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| ES2954366T3 (es) | 2013-10-22 | 2023-11-21 | Translate Bio Inc | Terapia de ácido ribonucleico mensajero para la deficiencia de argininosuccinato sintetasa |
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| TR201900649T4 (tr) | 2014-03-24 | 2019-02-21 | Translate Bio Inc | Oküler hastalıkların tedavisi için mrna tedavisi. |
| ES2750661T3 (es) * | 2014-04-25 | 2020-03-26 | Translate Bio Inc | Métodos para la purificación de ARN mensajero |
| JP6557722B2 (ja) | 2014-05-30 | 2019-08-07 | シャイアー ヒューマン ジェネティック セラピーズ インコーポレイテッド | 核酸の送達のための生分解性脂質 |
| ES2964588T3 (es) | 2014-06-24 | 2024-04-08 | Translate Bio Inc | Composiciones enriquecidas estereoquímicamente para la administración de ácidos nucleicos |
| CN114146063A (zh) | 2014-07-02 | 2022-03-08 | 川斯勒佰尔公司 | 信使rna的包封 |
| WO2016149508A1 (fr) | 2015-03-19 | 2016-09-22 | Shire Human Genetic Therapies, Inc. | Thérapie d'arnm pour maladie de pompe |
| KR101693166B1 (ko) | 2016-07-12 | 2017-01-06 | 정수영 | 분말 액체 혼합물용 누체 여과 건조 장치 |
| MA47605A (fr) * | 2017-02-27 | 2020-01-01 | Translate Bio Inc | Procédés de purification d'arn messager |
| AU2019258679A1 (en) | 2018-04-25 | 2020-10-15 | Ethris Gmbh | Cryoprotective agents for particulate formulations |
-
2018
- 2018-02-27 MA MA047605A patent/MA47605A/fr unknown
- 2018-02-27 IL IL268857A patent/IL268857B1/en unknown
- 2018-02-27 ES ES18711201T patent/ES2899323T3/es active Active
- 2018-02-27 EP EP21204742.7A patent/EP3971291A1/fr active Pending
- 2018-02-27 HU HUE18711201A patent/HUE059025T2/hu unknown
- 2018-02-27 AU AU2018224843A patent/AU2018224843A1/en active Pending
- 2018-02-27 DK DK18711201.6T patent/DK3585891T3/da active
- 2018-02-27 CA CA3054321A patent/CA3054321A1/fr active Pending
- 2018-02-27 US US15/906,864 patent/US10808241B2/en active Active
- 2018-02-27 WO PCT/US2018/019954 patent/WO2018157133A1/fr active Application Filing
- 2018-02-27 EP EP18711201.6A patent/EP3585891B1/fr active Active
-
2020
- 2020-10-14 US US17/070,877 patent/US11976272B2/en active Active
-
2021
- 2021-11-18 CY CY20211101004T patent/CY1124735T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| US20210123041A1 (en) | 2021-04-29 |
| CA3054321A1 (fr) | 2018-08-30 |
| ES2899323T3 (es) | 2022-03-10 |
| EP3585891A1 (fr) | 2020-01-01 |
| HUE059025T2 (hu) | 2022-10-28 |
| AU2018224843A1 (en) | 2019-09-19 |
| US10808241B2 (en) | 2020-10-20 |
| EP3971291A1 (fr) | 2022-03-23 |
| WO2018157133A1 (fr) | 2018-08-30 |
| US20180251755A1 (en) | 2018-09-06 |
| IL268857A (en) | 2019-10-31 |
| EP3585891B1 (fr) | 2021-10-27 |
| IL268857B1 (en) | 2024-05-01 |
| DK3585891T3 (da) | 2021-11-22 |
| US11976272B2 (en) | 2024-05-07 |
| CY1124735T1 (el) | 2022-07-22 |
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