MA46611A - Traitements combinés comprenant des imidazopyrazinones pour le traitement de troubles psychiatriques et/ou cognitifs - Google Patents
Traitements combinés comprenant des imidazopyrazinones pour le traitement de troubles psychiatriques et/ou cognitifsInfo
- Publication number
- MA46611A MA46611A MA046611A MA46611A MA46611A MA 46611 A MA46611 A MA 46611A MA 046611 A MA046611 A MA 046611A MA 46611 A MA46611 A MA 46611A MA 46611 A MA46611 A MA 46611A
- Authority
- MA
- Morocco
- Prior art keywords
- psychiatric
- treatment
- cognitive disorders
- combination treatments
- imidazopyrazinones
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/4985—Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
- A61K31/5513—1,4-Benzodiazepines, e.g. diazepam or clozapine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/553—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having at least one nitrogen and one oxygen as ring hetero atoms, e.g. loxapine, staurosporine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
La présente invention concerne des traitements combinés comprenant l'administration de composés qui sont des inhibiteurs d'enzyme pde1 et d'autres composés utiles dans le traitement de troubles psychiatriques et/ou cognitifs tels que, par exemple, le trouble du déficit de l'attention avec hyperactivité (tdah), la dépression, l'anxiété, la narcolepsie, la schizophrénie, la déficience cognitive ou la déficience cognitive associée à la schizophrénie (cias, pour "cognitive impairment associated with schizophrenia"). Des aspects séparés de l'invention concernent l'utilisation combinée desdits composés pour le traitement de troubles psychiatriques et/ou cognitifs. La présente invention concerne également des compositions pharmaceutiques comprenant lesdits inhibiteurs d'enzyme pde1 conjointement avec d'autres composés utiles dans le traitement de troubles psychiatriques et/ou cognitifs.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DKPA201600659 | 2016-10-28 | ||
PCT/EP2017/077497 WO2018078038A1 (fr) | 2016-10-28 | 2017-10-26 | Traitements combinés comprenant des imidazopyrazinones pour le traitement de troubles psychiatriques et/ou cognitifs |
Publications (2)
Publication Number | Publication Date |
---|---|
MA46611A true MA46611A (fr) | 2019-09-04 |
MA46611B1 MA46611B1 (fr) | 2020-08-31 |
Family
ID=60186299
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MA46611A MA46611B1 (fr) | 2016-10-28 | 2017-10-26 | Traitements combinés comprenant des imidazopyrazinones pour le traitement de troubles psychiatriques et/ou cognitifs |
Country Status (29)
Country | Link |
---|---|
US (1) | US10905688B2 (fr) |
EP (1) | EP3532064B1 (fr) |
JP (1) | JP2019536762A (fr) |
KR (1) | KR20190075068A (fr) |
CN (1) | CN109803658A (fr) |
AR (1) | AR109991A1 (fr) |
AU (1) | AU2017350473A1 (fr) |
BR (1) | BR112018013247A2 (fr) |
CA (1) | CA3041607A1 (fr) |
CL (1) | CL2019001091A1 (fr) |
CO (1) | CO2019002909A2 (fr) |
CY (1) | CY1123396T1 (fr) |
DK (1) | DK3532064T3 (fr) |
ES (1) | ES2816005T3 (fr) |
HR (1) | HRP20201326T1 (fr) |
HU (1) | HUE050403T2 (fr) |
IL (1) | IL265635A (fr) |
LT (1) | LT3532064T (fr) |
MA (1) | MA46611B1 (fr) |
ME (1) | ME03821B (fr) |
MX (1) | MX2019004763A (fr) |
PL (1) | PL3532064T3 (fr) |
PT (1) | PT3532064T (fr) |
RS (1) | RS60716B1 (fr) |
RU (1) | RU2019109039A (fr) |
SG (1) | SG11201903770UA (fr) |
SI (1) | SI3532064T1 (fr) |
WO (1) | WO2018078038A1 (fr) |
ZA (1) | ZA201902091B (fr) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
TW201629064A (zh) | 2014-10-10 | 2016-08-16 | H 朗德貝克公司 | 作爲pde1抑制劑之三唑並吡酮 |
JO3627B1 (ar) | 2015-04-30 | 2020-08-27 | H Lundbeck As | إيميدازو بيرازينونات على هيئة مثبطات pde1 |
TWI729109B (zh) | 2016-04-12 | 2021-06-01 | 丹麥商H 朗德貝克公司 | 作爲PDE1抑制劑的1,5-二氫-4H-吡唑并[3,4-d]嘧啶-4-酮和1,5-二氫-4H-吡唑并[4,3-c]吡啶-4-酮 |
ES2967489T3 (es) | 2016-10-18 | 2024-04-30 | H Lundbeck As | Imidazopirazinonas, pirazolopirimidinonas y pirazolopiridinonas como inhibidores de PDE1 |
JP2020500841A (ja) | 2016-10-28 | 2020-01-16 | ハー・ルンドベック・アクチエゼルスカベット | イミダゾピラジノンの投与を含む併用療法 |
CN109803658A (zh) | 2016-10-28 | 2019-05-24 | H.隆德贝克有限公司 | 包含用于治疗精神疾病和/或认知障碍的咪唑并吡嗪酮的组合治疗 |
MX2020008126A (es) | 2018-02-01 | 2020-09-18 | Japan Tobacco Inc | Compuesto de amida heterociclica nitrogenada y su uso para fines medicos. |
Family Cites Families (52)
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GB973361A (en) | 1960-05-11 | 1964-10-28 | Ciba Ltd | Pyrazolo-pyrimidines and process for their manufacture |
DE19709877A1 (de) | 1997-03-11 | 1998-09-17 | Bayer Ag | 1,5-Dihydro-pyrazolo[3,4-d]-pyrimidinon-derivate |
MY144532A (en) | 2001-08-20 | 2011-09-30 | Lundbeck & Co As H | Novel method for down-regulation of amyloid |
DE10238722A1 (de) | 2002-08-23 | 2004-03-11 | Bayer Ag | Selektive Phosphodiesterase 9A-Inhibitoren als Arzneimittel zur Verbesserung kognitiver Prozesse |
DE10238723A1 (de) | 2002-08-23 | 2004-03-11 | Bayer Ag | Phenyl-substituierte Pyrazolyprimidine |
DE10238724A1 (de) | 2002-08-23 | 2004-03-04 | Bayer Ag | Alkyl-substituierte Pyrazolpyrimidine |
WO2004099211A1 (fr) | 2003-05-09 | 2004-11-18 | Bayer Healthcare Ag | Pyrazolopyrimidines substituees par 6-cyclylmethyle et 6-alkylmethyle |
EP2805953B1 (fr) | 2004-12-21 | 2016-03-09 | Takeda Pharmaceutical Company Limited | Inhibiteurs de peptidase dipeptidyl |
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TWI404721B (zh) | 2009-01-26 | 2013-08-11 | Pfizer | 胺基-雜環化合物 |
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WO2011153136A1 (fr) | 2010-05-31 | 2011-12-08 | Intra-Cellular Therapies, Inc. | Composés organiques |
PL3339323T3 (pl) | 2010-08-12 | 2020-05-18 | Eli Lilly And Company | Przeciwciała przeciwko peptydowi N3pGlu amyloidu beta i ich zastosowania |
MX2013003093A (es) | 2010-09-20 | 2013-10-28 | Envivo Pharmaceuticals Inc | Compuestos de imidazotriazinona. |
US20130196986A1 (en) | 2010-09-21 | 2013-08-01 | Marc Labroli | Triazolopyrazinones as p2x7 receptor antagonists |
JO3089B1 (ar) | 2010-11-19 | 2017-03-15 | H Lundbeck As | مشتقات ايميدازول كمثبطات لانزيمات pde10a |
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WO2012136552A1 (fr) | 2011-04-08 | 2012-10-11 | H. Lundbeck A/S | Anticorps spécifiquement dirigés contre la protéine bêta-amyloïde pyroglutamatée |
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JP5783297B2 (ja) | 2013-08-06 | 2015-09-24 | 株式会社デンソー | 力学量センサ |
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JP5797815B1 (ja) | 2014-06-27 | 2015-10-21 | 細田建設株式会社 | 後施工アンカー及びその施工方法 |
US20160083391A1 (en) | 2014-09-18 | 2016-03-24 | Sunovion Pharmaceuticals Inc. | Tricyclic piperazine derivative |
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US20160083400A1 (en) | 2014-09-18 | 2016-03-24 | Sunovion Pharmaceuticals Inc. | Tricyclic guanidine derivative |
TW201629064A (zh) | 2014-10-10 | 2016-08-16 | H 朗德貝克公司 | 作爲pde1抑制劑之三唑並吡酮 |
JO3458B1 (ar) | 2014-11-10 | 2020-07-05 | H Lundbeck As | 2- أمينو-6- (دايفلوروميثيل) – 5، 5- ديفلورو-6-فينيل-3،4، 5، 6-تيتراهيدروبيريدين كمثبطات bace1 |
CR20170187A (es) | 2014-11-10 | 2018-02-01 | H Lundbeck As | 2-Amino-3,5-difluoro-6-metil-6-fenil-3,4,5,6-tetrahidropiridinas en calidad de inhibidores de BACE1 para el tratamiento de la enfermedad de Alzheimer |
MA40941A (fr) | 2014-11-10 | 2017-09-19 | H Lundbeck As | 2-amino-5,5-difluoro-6-(fluorométhyl)-6-phényl-3,4,5,6-tétrahydropyridines comme inhibiteurs de bace1 |
TW201639851A (zh) | 2015-03-16 | 2016-11-16 | 大日本住友製藥股份有限公司 | 雙環咪唑衍生物 |
US20160311831A1 (en) | 2015-04-22 | 2016-10-27 | H. Lundbeck A/S | Imidazotriazinones as PDE1 Inhibitors |
JO3627B1 (ar) | 2015-04-30 | 2020-08-27 | H Lundbeck As | إيميدازو بيرازينونات على هيئة مثبطات pde1 |
JO3711B1 (ar) | 2015-07-13 | 2021-01-31 | H Lundbeck As | أجسام مضادة محددة لبروتين تاو وطرق استعمالها |
US20180244645A1 (en) | 2015-08-12 | 2018-08-30 | H. Lundbeck A/S | 2-amino-3-fluoro-3-(fluoromethyl)-6-methyl-6-phenyl-3,4,5,6-tetrahydropyridines as bace1 inhibitors |
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AR107456A1 (es) | 2016-02-12 | 2018-05-02 | Lilly Co Eli | Inhibidor de pde1 |
TWI729109B (zh) | 2016-04-12 | 2021-06-01 | 丹麥商H 朗德貝克公司 | 作爲PDE1抑制劑的1,5-二氫-4H-吡唑并[3,4-d]嘧啶-4-酮和1,5-二氫-4H-吡唑并[4,3-c]吡啶-4-酮 |
JP2018076285A (ja) | 2016-09-14 | 2018-05-17 | 大日本住友製薬株式会社 | 二環性イミダゾロ誘導体を含む医薬 |
ES2967489T3 (es) | 2016-10-18 | 2024-04-30 | H Lundbeck As | Imidazopirazinonas, pirazolopirimidinonas y pirazolopiridinonas como inhibidores de PDE1 |
CN109803658A (zh) | 2016-10-28 | 2019-05-24 | H.隆德贝克有限公司 | 包含用于治疗精神疾病和/或认知障碍的咪唑并吡嗪酮的组合治疗 |
JP2020500841A (ja) | 2016-10-28 | 2020-01-16 | ハー・ルンドベック・アクチエゼルスカベット | イミダゾピラジノンの投与を含む併用療法 |
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2017
- 2017-10-26 CN CN201780063182.9A patent/CN109803658A/zh active Pending
- 2017-10-26 AU AU2017350473A patent/AU2017350473A1/en not_active Abandoned
- 2017-10-26 KR KR1020197011509A patent/KR20190075068A/ko not_active Application Discontinuation
- 2017-10-26 ME MEP-2020-170A patent/ME03821B/fr unknown
- 2017-10-26 JP JP2019522523A patent/JP2019536762A/ja active Pending
- 2017-10-26 LT LTEP17791080.9T patent/LT3532064T/lt unknown
- 2017-10-26 PT PT177910809T patent/PT3532064T/pt unknown
- 2017-10-26 ES ES17791080T patent/ES2816005T3/es active Active
- 2017-10-26 WO PCT/EP2017/077497 patent/WO2018078038A1/fr unknown
- 2017-10-26 MX MX2019004763A patent/MX2019004763A/es unknown
- 2017-10-26 RS RS20200975A patent/RS60716B1/sr unknown
- 2017-10-26 RU RU2019109039A patent/RU2019109039A/ru not_active Application Discontinuation
- 2017-10-26 SI SI201730388T patent/SI3532064T1/sl unknown
- 2017-10-26 PL PL17791080T patent/PL3532064T3/pl unknown
- 2017-10-26 HU HUE17791080A patent/HUE050403T2/hu unknown
- 2017-10-26 MA MA46611A patent/MA46611B1/fr unknown
- 2017-10-26 DK DK17791080.9T patent/DK3532064T3/da active
- 2017-10-26 BR BR112018013247A patent/BR112018013247A2/pt not_active Application Discontinuation
- 2017-10-26 CA CA3041607A patent/CA3041607A1/fr not_active Abandoned
- 2017-10-26 EP EP17791080.9A patent/EP3532064B1/fr active Active
- 2017-10-26 US US16/345,136 patent/US10905688B2/en active Active
- 2017-10-26 SG SG11201903770UA patent/SG11201903770UA/en unknown
- 2017-10-27 AR ARP170102997A patent/AR109991A1/es unknown
-
2019
- 2019-03-26 IL IL265635A patent/IL265635A/en unknown
- 2019-03-27 CO CONC2019/0002909A patent/CO2019002909A2/es unknown
- 2019-04-03 ZA ZA2019/02091A patent/ZA201902091B/en unknown
- 2019-04-22 CL CL2019001091A patent/CL2019001091A1/es unknown
-
2020
- 2020-08-24 CY CY20201100788T patent/CY1123396T1/el unknown
- 2020-08-25 HR HRP20201326TT patent/HRP20201326T1/hr unknown
Also Published As
Publication number | Publication date |
---|---|
SI3532064T1 (sl) | 2020-10-30 |
EP3532064B1 (fr) | 2020-07-29 |
ZA201902091B (en) | 2020-10-28 |
MX2019004763A (es) | 2019-07-01 |
LT3532064T (lt) | 2020-09-25 |
RS60716B1 (sr) | 2020-09-30 |
ES2816005T3 (es) | 2021-03-31 |
PL3532064T3 (pl) | 2020-11-16 |
ME03821B (fr) | 2021-04-20 |
EP3532064A1 (fr) | 2019-09-04 |
WO2018078038A1 (fr) | 2018-05-03 |
AR109991A1 (es) | 2019-02-13 |
BR112018013247A2 (pt) | 2018-12-04 |
KR20190075068A (ko) | 2019-06-28 |
CL2019001091A1 (es) | 2019-07-05 |
HUE050403T2 (hu) | 2020-12-28 |
CO2019002909A2 (es) | 2019-06-19 |
US10905688B2 (en) | 2021-02-02 |
MA46611B1 (fr) | 2020-08-31 |
IL265635A (en) | 2019-05-30 |
PT3532064T (pt) | 2020-09-03 |
SG11201903770UA (en) | 2019-05-30 |
JP2019536762A (ja) | 2019-12-19 |
RU2019109039A3 (fr) | 2021-01-29 |
RU2019109039A (ru) | 2020-11-30 |
CA3041607A1 (fr) | 2018-05-03 |
CY1123396T1 (el) | 2021-12-31 |
CN109803658A (zh) | 2019-05-24 |
HRP20201326T1 (hr) | 2020-11-27 |
DK3532064T3 (da) | 2020-08-24 |
AU2017350473A1 (en) | 2019-04-18 |
US20190282571A1 (en) | 2019-09-19 |
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