MA38126B1 - 6-((s)-1-{1-[5-(2-hydroxy-éthoxy)-pyridin-2-yl]-1hpyrazol-3-yl}- éthyl)-3h1,3-benzothiazol-2-one comme antagoniste des récepteurs de l’ampa dépendants de tarp-gamma 8 - Google Patents
6-((s)-1-{1-[5-(2-hydroxy-éthoxy)-pyridin-2-yl]-1hpyrazol-3-yl}- éthyl)-3h1,3-benzothiazol-2-one comme antagoniste des récepteurs de l’ampa dépendants de tarp-gamma 8Info
- Publication number
- MA38126B1 MA38126B1 MA38126A MA38126A MA38126B1 MA 38126 B1 MA38126 B1 MA 38126B1 MA 38126 A MA38126 A MA 38126A MA 38126 A MA38126 A MA 38126A MA 38126 B1 MA38126 B1 MA 38126B1
- Authority
- MA
- Morocco
- Prior art keywords
- tarp
- dependent
- receptor antagonist
- amfa
- benzothiazol
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A61P29/02—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Pain & Pain Management (AREA)
- Epidemiology (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261730273P | 2012-11-27 | 2012-11-27 | |
| PCT/US2013/070885 WO2014085153A1 (en) | 2012-11-27 | 2013-11-20 | 6-((s)-1-{1-[5-(2-hydroxy-ethoxy)-pyridin-2-yl]-1h-pyrazol-3-yl}- ethyl)-3h-1,3-benzothiazol-2-one as a tarp-gamma 8 dependent ampa receptor antagonist |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MA38126A1 MA38126A1 (fr) | 2017-03-31 |
| MA38126B1 true MA38126B1 (fr) | 2017-11-30 |
Family
ID=49753484
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MA38126A MA38126B1 (fr) | 2012-11-27 | 2013-11-20 | 6-((s)-1-{1-[5-(2-hydroxy-éthoxy)-pyridin-2-yl]-1hpyrazol-3-yl}- éthyl)-3h1,3-benzothiazol-2-one comme antagoniste des récepteurs de l’ampa dépendants de tarp-gamma 8 |
Country Status (35)
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW201609719A (zh) * | 2014-05-28 | 2016-03-16 | 美國禮來大藥廠 | 作為ＴＡＲＰ－γ８依賴性ＡＭＰＡ受體拮抗劑之６－經取代－３Ｈ－１，３－苯并噻唑－２－酮化合物 |
| KR20170141769A (ko) | 2015-04-29 | 2017-12-26 | 얀센 파마슈티카 엔.브이. | 인돌론 화합물 및 ampa 수용체 조절제로서의 이의 용도 |
| JP6804469B2 (ja) * | 2015-04-29 | 2020-12-23 | ヤンセン ファーマシューティカ エヌ．ベー． | ベンゾイミダゾロン及びベンゾチアゾロン化合物並びにａｍｐａ受容体調節因子としてのそれらの使用 |
| ES2865330T3 (es) | 2015-04-29 | 2021-10-15 | Janssen Pharmaceutica Nv | Azabenzimidazoles y su uso como moduladores del receptor AMPA |
| MX373652B (es) | 2015-04-29 | 2020-04-02 | Janssen Pharmaceutica Nv | Imidazopirazinas y pirazolopirimidinas y su uso como moduladores del receptor de ampa. |
| JP6953527B2 (ja) * | 2016-10-26 | 2021-10-27 | ヤンセン ファーマシューティカ エヌ．ベー． | 縮合二環ピリジン化合物、及びａｍｐａ受容体調節因子としてのそれらの使用 |
| RU2650523C1 (ru) | 2017-07-24 | 2018-04-16 | федеральное государственное автономное образовательное учреждение высшего образования "Казанский (Приволжский) федеральный университет" (ФГАОУ ВО КФУ) | Производное пиридоксина для лечения эпилепсии |
| RU2703286C1 (ru) * | 2019-06-18 | 2019-10-16 | федеральное государственное автономное образовательное учреждение высшего образования "Казанский (Приволжский) федеральный университет" (ФГАОУ ВО КФУ) | Соли (5-гидрокси-3,4-бис(гидроксиметил)-6-метилпиридин-2-ил)метансульфокислоты и способ их получения |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MY132385A (en) * | 1995-08-31 | 2007-10-31 | Novartis Ag | 2,3-dioxo-1,2,3,4-tetrahydro-quinoxalinyl derivatives |
| JP2000281676A (ja) * | 1999-01-25 | 2000-10-10 | Yamanouchi Pharmaceut Co Ltd | Ａｍｐａ拮抗化合物の新規製造法 |
| ES2320973T3 (es) * | 2000-06-12 | 2009-06-01 | EISAI R&D MANAGEMENT CO., LTD. | Compuestos de 1,2-dihidropiridina, procedimiento para su preparacion y uso de los mismos. |
| US8995993B2 (en) * | 2000-10-11 | 2015-03-31 | Gogo Llc | System for managing mobile internet protocol addresses in an airborne wireless cellular network |
| DE602005009021D1 (de) * | 2004-12-17 | 2008-09-25 | Lilly Co Eli | Neue mch-rezeptorantagonisten |
| WO2007076161A2 (en) | 2005-12-27 | 2007-07-05 | Myriad Genetics, Inc | Compounds with therapeutic activity |
| TW200817385A (en) * | 2006-07-04 | 2008-04-16 | Organon Nv | Heterocyclic derivatives |
| JP2012505198A (ja) * | 2008-10-08 | 2012-03-01 | ファイザー・インク | Ｃｎｓ障害を治療する際にａｍｐａ調節剤として使用するためのテトラヒドロフラニルスルホンアミド |
| PE20120008A1 (es) * | 2009-01-12 | 2012-01-24 | Icagen Inc | Derivados de fenoxi bencenosulfonamida |
| EP2576544A4 (en) * | 2010-06-01 | 2013-09-11 | Angion Biomedica Corp | INHIBITORS OF CYTOCHROMES P450 AND USES THEREOF |
| EP2694472B1 (en) * | 2011-04-05 | 2020-03-11 | Takeda Pharmaceutical Company Limited | Sulfonamide derivative and use thereof |
| TW201609719A (zh) * | 2014-05-28 | 2016-03-16 | 美國禮來大藥廠 | 作為ＴＡＲＰ－γ８依賴性ＡＭＰＡ受體拮抗劑之６－經取代－３Ｈ－１，３－苯并噻唑－２－酮化合物 |
-
2013
- 2013-11-17 JO JOP/2013/0331A patent/JO3225B1/ar active
- 2013-11-18 TW TW102141949A patent/TWI618705B/zh not_active IP Right Cessation
- 2013-11-18 AR ARP130104242A patent/AR093527A1/es unknown
- 2013-11-18 TW TW106144388A patent/TW201825484A/zh unknown
- 2013-11-20 PL PL13802786T patent/PL2925754T3/pl unknown
- 2013-11-20 HR HRP20170274TT patent/HRP20170274T1/hr unknown
- 2013-11-20 HU HUE13802786A patent/HUE033447T2/en unknown
- 2013-11-20 ES ES13802786.7T patent/ES2618260T3/es active Active
- 2013-11-20 MA MA38126A patent/MA38126B1/fr unknown
- 2013-11-20 DK DK13802786.7T patent/DK2925754T3/en active
- 2013-11-20 PE PE2015000694A patent/PE20151728A1/es active IP Right Grant
- 2013-11-20 MY MYPI2015701544A patent/MY177721A/en unknown
- 2013-11-20 US US14/084,683 patent/US8765960B2/en active Active
- 2013-11-20 MX MX2015006697A patent/MX356478B/es active IP Right Grant
- 2013-11-20 WO PCT/US2013/070885 patent/WO2014085153A1/en not_active Ceased
- 2013-11-20 CA CA2889243A patent/CA2889243C/en active Active
- 2013-11-20 AP AP2015008489A patent/AP2015008489A0/xx unknown
- 2013-11-20 CN CN201380061495.2A patent/CN104797578B/zh active Active
- 2013-11-20 PT PT138027867T patent/PT2925754T/pt unknown
- 2013-11-20 EP EP13802786.7A patent/EP2925754B1/en active Active
- 2013-11-20 KR KR1020157013470A patent/KR101693133B1/ko active Active
- 2013-11-20 SI SI201330464A patent/SI2925754T1/sl unknown
- 2013-11-20 SG SG11201504164VA patent/SG11201504164VA/en unknown
- 2013-11-20 JP JP2015545099A patent/JP6246227B2/ja active Active
- 2013-11-20 BR BR112015011200A patent/BR112015011200A2/pt not_active IP Right Cessation
- 2013-11-20 AU AU2013352594A patent/AU2013352594B2/en active Active
- 2013-11-20 EA EA201590823A patent/EA026686B1/ru not_active IP Right Cessation
- 2013-11-20 UA UAA201504865A patent/UA114345C2/uk unknown
-
2015
- 2015-05-14 DO DO2015000113A patent/DOP2015000113A/es unknown
- 2015-05-14 IL IL238831A patent/IL238831B/en not_active IP Right Cessation
- 2015-05-20 CR CR20150267A patent/CR20150267A/es unknown
- 2015-05-22 TN TNP2015000200A patent/TN2015000200A1/fr unknown
- 2015-05-25 PH PH12015501154A patent/PH12015501154B1/en unknown
- 2015-05-26 CL CL2015001419A patent/CL2015001419A1/es unknown
- 2015-05-26 ZA ZA2015/03733A patent/ZA201503733B/en unknown
-
2017
- 2017-02-24 CY CY20171100252T patent/CY1118657T1/el unknown
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| MA38126B1 (fr) | 6-((s)-1-{1-[5-(2-hydroxy-éthoxy)-pyridin-2-yl]-1hpyrazol-3-yl}- éthyl)-3h1,3-benzothiazol-2-one comme antagoniste des récepteurs de l’ampa dépendants de tarp-gamma 8 | |
| MA32351B1 (fr) | Derives d'aminodihydrothiazine a titre d'inhibiteurs de bace pour le traitement de la maladie d'alzheimer | |
| MA37405A1 (fr) | Composés hétérocyclyle | |
| MA33492B1 (fr) | Inhibiteurs de bace | |
| EA201490912A1 (ru) | Производные [1,2,3]триазоло[4,5-d]пиримидина в качестве агонистов каннабиноидного рецептора 2 | |
| TN2009000085A1 (fr) | Derives de pyrido (2,3-d) pyrimidinone et leur utilisation comme inhibiteurs de pi3 | |
| GEP20146146B (en) | Pyrrolopyrimidine compounds as inhibitors of cdk4/6 | |
| MA35452B1 (fr) | 3-pyrimidin-4-yl-oxazolidin-2-ones comme inhibiteurs d'idh mutante | |
| MA34644B1 (fr) | Dérivés de pyrazole aminopyrimidine en tant que modulateurs du lrrk2 | |
| MA39152B1 (fr) | Cyclopentanes substitués en 1,2 utilisés comme antagonistes du récepteur d'orexine | |
| MX2012006909A (es) | LIGANDOS DEL RECEPTOR NICOTINICO NEURONAL A4ß2 DE ACETILCOLINA. | |
| MX2009000169A (es) | Derivados de purinona como agonistas de hm74a. | |
| UA83875C2 (ru) | Производные хинолина для применения в качестве микобактериальных ингибиторов | |
| MA35893B1 (fr) | Dérivés d'amide hétérocyclique comme antagonistes du récepteur p2x7 | |
| DE602007012313D1 (de) | Als a2b-adenosinrezeptorantagonisten geeignete 5-phenyl-6-pyridin-4-yl-1,3-dihydro-2h-imidazoä4,5-büpyridin-2-onderivate | |
| TN2014000519A1 (en) | Pyrimidinone derivatives as antimalarial agents | |
| MA35188B1 (fr) | Tétrahydroquinolines à fusion cycloalkyle en tant que modulateurs de l'activité du récepteur crth2 | |
| MY178583A (en) | Hydantoin derivative | |
| MA34663B1 (fr) | Composés 3-phénylsulfanylméthyl-bicyclo[3.1.0]hexane 4-substitués en tant qu'antagonistes de mglur 2/3 | |
| NO20076161L (no) | Fremgangsmater for fremstilling av 4-bifenylazetidin-2-oner | |
| CY1117011T1 (el) | Παραγωγα αζολιου | |
| EA201390327A1 (ru) | Гетероциклильные соединения в качестве лигандов гистаминовых hрецепторов | |
| MA33828B1 (fr) | Dérivés 8-hydroxyquinoline-7-carboxamide secondaires et leurs utilisations en tant qu'agents antifongiques | |
| GEP20156269B (en) | New secondary 8-hydroxyquinoline-7- carboxamide derivatives | |
| PH12013500588A1 (en) | Indole derivatives |