MA33828B1 - Dérivés 8-hydroxyquinoline-7-carboxamide secondaires et leurs utilisations en tant qu'agents antifongiques - Google Patents

Dérivés 8-hydroxyquinoline-7-carboxamide secondaires et leurs utilisations en tant qu'agents antifongiques

Info

Publication number
MA33828B1
MA33828B1 MA34971A MA34971A MA33828B1 MA 33828 B1 MA33828 B1 MA 33828B1 MA 34971 A MA34971 A MA 34971A MA 34971 A MA34971 A MA 34971A MA 33828 B1 MA33828 B1 MA 33828B1
Authority
MA
Morocco
Prior art keywords
hydroxyquinoline
antifungal agents
carboxamide derivatives
compounds
carboxamide
Prior art date
Application number
MA34971A
Other languages
Arabic (ar)
English (en)
Inventor
Stefania Gagliardi
Sordo Simone Del
Federico Mailland
Michela Legora
Original Assignee
Polichem Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=42027760&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MA33828(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Polichem Sa filed Critical Polichem Sa
Publication of MA33828B1 publication Critical patent/MA33828B1/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Quinoline Compounds (AREA)

Abstract

Cette invention concerne des dérivés de 8-hydroxyquinoline-7-carboxamide secondaires de formule générale (I) et leurs sels pharmaceutiquement acceptables. Ces composés sont utiles en tant qu'agents antifongiques. Plus spécifiquement, ces composés ont été testés contre
MA34971A 2009-12-29 2012-06-15 Dérivés 8-hydroxyquinoline-7-carboxamide secondaires et leurs utilisations en tant qu'agents antifongiques MA33828B1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP09180899A EP2345642A1 (fr) 2009-12-29 2009-12-29 Dérivés de 8-hydroxyquinoline-7-carboxamide secondaire pour une utilisation en tant qu'agents antifongiques
PCT/EP2010/070791 WO2011080265A1 (fr) 2009-12-29 2010-12-28 Dérivés de 8-hydroxyquinoline-7-carboxamide secondaires et leurs utilisations en tant qu'agents antifongiques

Publications (1)

Publication Number Publication Date
MA33828B1 true MA33828B1 (fr) 2012-12-03

Family

ID=42027760

Family Applications (1)

Application Number Title Priority Date Filing Date
MA34971A MA33828B1 (fr) 2009-12-29 2012-06-15 Dérivés 8-hydroxyquinoline-7-carboxamide secondaires et leurs utilisations en tant qu'agents antifongiques

Country Status (31)

Country Link
US (1) US8969380B2 (fr)
EP (2) EP2345642A1 (fr)
JP (1) JP5755244B2 (fr)
KR (1) KR101620377B1 (fr)
CN (2) CN102712597A (fr)
AU (1) AU2010338268B2 (fr)
BR (1) BR112012015735A2 (fr)
CA (1) CA2783216A1 (fr)
CL (1) CL2012001758A1 (fr)
CY (1) CY1114862T1 (fr)
DK (1) DK2519503T3 (fr)
EA (1) EA024115B1 (fr)
ES (1) ES2442899T3 (fr)
GE (1) GEP20156301B (fr)
GT (1) GT201200215A (fr)
HK (1) HK1178522A1 (fr)
HR (1) HRP20131176T1 (fr)
IL (1) IL220428A (fr)
MA (1) MA33828B1 (fr)
MX (1) MX2012007747A (fr)
MY (1) MY162991A (fr)
NI (1) NI201200116A (fr)
NZ (1) NZ600785A (fr)
PL (1) PL2519503T3 (fr)
PT (1) PT2519503E (fr)
RS (1) RS53090B (fr)
SG (1) SG181587A1 (fr)
SI (1) SI2519503T1 (fr)
TN (1) TN2012000321A1 (fr)
UA (1) UA110102C2 (fr)
WO (1) WO2011080265A1 (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2345641A1 (fr) * 2009-12-29 2011-07-20 Polichem S.A. Nouveaux dérivés de 8-hydroxyquinoline-7-carboxamide secondaire
EP2345643A1 (fr) * 2009-12-29 2011-07-20 Polichem S.A. Nouveaux dérivés de 8-hydroxyquinoline-7-carboxamide et leurs utilisations
CN110563642A (zh) * 2019-09-30 2019-12-13 赵洁 抗真菌化合物及其应用

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE540842C (de) 1930-08-06 1931-12-28 Chinosol Fabrik Akt Ges Verfahren zur Darstellung der 8-Acetyloxychinolin-7-carbonsaeure
FR2160718A1 (en) * 1971-11-23 1973-07-06 Roussel Uclaf 7-benzyl aminomethyl-8-hydroxy quinolines - bacteriostats and fungistats
GB8419658D0 (en) * 1984-08-01 1984-09-05 Wellcome Found Nitrogen containing heterocyclic compounds
JPH01136152A (ja) * 1987-11-21 1989-05-29 Konica Corp ハロゲン化銀カラー写真感光材料
EP0927164A1 (fr) 1996-09-10 1999-07-07 PHARMACIA & UPJOHN COMPANY 8-hydroxyquinoleines 7-substituees utilisees comme agents antiviraux
HUP0302367A2 (hu) 2000-10-12 2003-11-28 Merck & Co., Inc. HIV Integráz inhibitorokként hasznos aza- és poliazanaftalenil-karboxamidok, ezeket tartalmazó gyógyszerkészítmények
JP4287649B2 (ja) * 2000-10-12 2009-07-01 メルク エンド カムパニー インコーポレーテッド Ｈｉｖインテグラーゼ阻害薬として有用なアザ−およびポリアザ−ナフタレニルカルボキサミド類
BR0207809A (pt) 2001-03-01 2004-03-09 Shionogi & Co Compostos heteroarila contendo nitrogênio possuindo atividade inibidora contra integrase de hiv
JP4795022B2 (ja) * 2003-09-30 2011-10-19 エーザイ・アール・アンド・ディー・マネジメント株式会社 ヘテロ環化合物を含有する新規な抗真菌剤
FR2889192A1 (fr) * 2005-07-27 2007-02-02 Cytomics Systems Sa Composes antifongiques, compositions contenant ces composes et leurs utilisations
JP2009544631A (ja) * 2006-07-25 2009-12-17 エンビボ ファーマシューティカルズ インコーポレイテッド キノリン誘導体
EP2345641A1 (fr) * 2009-12-29 2011-07-20 Polichem S.A. Nouveaux dérivés de 8-hydroxyquinoline-7-carboxamide secondaire
EP2345643A1 (fr) * 2009-12-29 2011-07-20 Polichem S.A. Nouveaux dérivés de 8-hydroxyquinoline-7-carboxamide et leurs utilisations

Also Published As

Publication number Publication date
SG181587A1 (en) 2012-07-30
EP2519503A1 (fr) 2012-11-07
AU2010338268B2 (en) 2014-02-20
SI2519503T1 (sl) 2014-01-31
GEP20156301B (en) 2015-06-25
CN105168213A (zh) 2015-12-23
NZ600785A (en) 2013-11-29
EP2519503B1 (fr) 2013-10-23
PT2519503E (pt) 2013-12-24
AU2010338268A1 (en) 2012-07-19
KR20120107506A (ko) 2012-10-02
RS53090B (en) 2014-06-30
EA201270671A1 (ru) 2012-12-28
US20120329797A1 (en) 2012-12-27
AU2010338268A2 (en) 2012-07-26
HRP20131176T1 (hr) 2014-01-17
CL2012001758A1 (es) 2013-03-22
EA024115B1 (ru) 2016-08-31
CA2783216A1 (fr) 2011-07-07
MY162991A (en) 2017-07-31
BR112012015735A2 (pt) 2016-05-17
CN102712597A (zh) 2012-10-03
JP5755244B2 (ja) 2015-07-29
CY1114862T1 (el) 2016-12-14
UA110102C2 (uk) 2015-11-25
TN2012000321A1 (en) 2013-12-12
GT201200215A (es) 2014-03-21
IL220428A0 (en) 2012-08-30
JP2013515756A (ja) 2013-05-09
MX2012007747A (es) 2012-08-01
PL2519503T3 (pl) 2014-04-30
US8969380B2 (en) 2015-03-03
EP2345642A1 (fr) 2011-07-20
IL220428A (en) 2015-04-30
HK1178522A1 (en) 2013-09-13
NI201200116A (es) 2013-04-22
WO2011080265A1 (fr) 2011-07-07
ES2442899T3 (es) 2014-02-14
KR101620377B1 (ko) 2016-05-12
DK2519503T3 (da) 2013-11-18

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