MA35347B1 - Procedes therapeuiques - Google Patents

Procedes therapeuiques

Info

Publication number
MA35347B1
MA35347B1 MA36751A MA36751A MA35347B1 MA 35347 B1 MA35347 B1 MA 35347B1 MA 36751 A MA36751 A MA 36751A MA 36751 A MA36751 A MA 36751A MA 35347 B1 MA35347 B1 MA 35347B1
Authority
MA
Morocco
Prior art keywords
therapeutic methods
hepatitis
iib
administration
compound
Prior art date
Application number
MA36751A
Other languages
English (en)
Inventor
Jill Walker
Christian Voitenleitner
Original Assignee
Glaxosmithkline Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=47715500&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MA35347(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Glaxosmithkline Llc filed Critical Glaxosmithkline Llc
Publication of MA35347B1 publication Critical patent/MA35347B1/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/7056—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing five-membered rings with nitrogen as a ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/69—Boron compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A61K31/343—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/21—Interferons [IFN]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/21—Interferons [IFN]
    • A61K38/212—IFN-alpha
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/21—Interferons [IFN]
    • A61K38/215—IFN-beta
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Virology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

La présente invention concerne un procédé pour le traitement de l'hépatite c chez un humain le nécessitant comprenant l'administration d'un composé de formule (ii) ou (iib) décrites ici ou d'un de ses sels pharmaceutiquement acceptables en combinaison avec un ou plusieurs autres agents thérapeutiques contre l'hépatite c.
MA36751A 2011-08-17 2014-02-12 Procedes therapeuiques MA35347B1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161524429P 2011-08-17 2011-08-17
US201161526787P 2011-08-24 2011-08-24
PCT/US2012/051349 WO2013025992A1 (fr) 2011-08-17 2012-08-17 Procédés thérapeutiques

Publications (1)

Publication Number Publication Date
MA35347B1 true MA35347B1 (fr) 2014-08-01

Family

ID=47715500

Family Applications (1)

Application Number Title Priority Date Filing Date
MA36751A MA35347B1 (fr) 2011-08-17 2014-02-12 Procedes therapeuiques

Country Status (21)

Country Link
US (2) US9119868B2 (fr)
EP (1) EP2744342B1 (fr)
JP (2) JP6121419B2 (fr)
KR (2) KR20140093209A (fr)
CN (2) CN106109479A (fr)
AU (1) AU2012296446B2 (fr)
BR (1) BR112014003556A2 (fr)
CA (1) CA2843502C (fr)
CL (2) CL2014000394A1 (fr)
CO (1) CO6880064A2 (fr)
CR (1) CR20140075A (fr)
DO (1) DOP2014000030A (fr)
EA (2) EA024357B1 (fr)
ES (1) ES2735542T3 (fr)
IL (1) IL230484A (fr)
MA (1) MA35347B1 (fr)
MX (1) MX2014001833A (fr)
PE (1) PE20141391A1 (fr)
SG (1) SG10201606646RA (fr)
WO (1) WO2013025992A1 (fr)
ZA (2) ZA201400435B (fr)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20140093209A (ko) * 2011-08-17 2014-07-25 글락소스미스클라인 엘엘씨 치료 방법
ME02588B (fr) * 2011-08-19 2017-06-20 Glaxo Group Ltd Composés benzofuranes pour le traitement d'infections par le virus de l'hépatite c
KR20170083108A (ko) * 2014-11-10 2017-07-17 글락소스미스클라인 인털렉츄얼 프로퍼티 (넘버 2) 리미티드 C형 간염에 대한 장기 작용 약학적 조성물
AU2015344741A1 (en) * 2014-11-10 2017-05-25 Glaxosmithkline Intellectual Property (No.2) Limited Combination long acting compositions and methods for hepatitis C
CN105732602B (zh) * 2015-09-23 2017-04-19 常州寅盛药业有限公司 作为ns4b抑制剂的苯并呋喃类似物
CN110799193B (zh) * 2017-03-21 2023-12-12 斯克利普斯研究院 铜和镍催化的脱羧硼化反应
TW202130635A (zh) * 2019-10-25 2021-08-16 日商大日本住友製藥股份有限公司 新穎取代縮環型化合物

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU5920400A (en) * 1999-07-07 2001-01-22 Du Pont Pharmaceuticals Company Cell-based assay systems for examining hcv ns3 protease activity
WO2004041201A2 (fr) * 2002-11-01 2004-05-21 Viropharma Incorporated Composes de benzofurane, compositions et methodes utilisees pour le traitement et la prophylaxie des infections virales induites par l'hepatite c et des maladies associees
US20070269420A1 (en) 2003-11-24 2007-11-22 Chunduru Srinivas K Compounds, Compositions and Methods for Treatment and Prophylaxis of Hepatitis C Viral Infections and Associated Diseases
EP2015757A4 (fr) * 2006-05-02 2011-01-26 Anacor Pharmaceuticals Inc Substances thérapeutiques contenant du bore résistant à l'hydrolyse et méthodes d'utilisation
EP2187883A2 (fr) 2007-08-10 2010-05-26 Genelabs Technologies, Inc. Entités chimiques bicycliques azotées pour traiter les infections virales
GB0719366D0 (en) * 2007-10-03 2007-11-14 Smithkline Beecham Corp Compounds
KR20100117073A (ko) * 2008-02-14 2010-11-02 에프. 호프만-라 로슈 아게 헤테로사이클릭 항바이러스 화합물
WO2009137500A1 (fr) * 2008-05-05 2009-11-12 Wyeth Composés de benzofurane substitués en 6 pour traiter l’infection par le virus de l’hépatite c
WO2011050284A1 (fr) * 2009-10-23 2011-04-28 Glaxosmithkline Llc Agents antiviraux de pyrazolylpyridine
AR080185A1 (es) * 2010-02-19 2012-03-21 Glaxo Group Ltd Derivados de acido boronico y benzofurano, composiciones farmaceuticas que los contienen,y uso de los mismos en el tratamiento y/o prevencion de infecciones virales, en particular por el virus de hepatitis c(hcv).
WO2012067663A1 (fr) * 2010-11-18 2012-05-24 Glaxo Group Limited Composés
WO2013025975A1 (fr) * 2011-08-17 2013-02-21 Glaxosmithkline Llc Traitements combinés pour l'hépatite c
KR20140093209A (ko) * 2011-08-17 2014-07-25 글락소스미스클라인 엘엘씨 치료 방법
ME02588B (fr) * 2011-08-19 2017-06-20 Glaxo Group Ltd Composés benzofuranes pour le traitement d'infections par le virus de l'hépatite c
EP2747569A4 (fr) * 2011-08-24 2015-07-08 Glaxosmithkline Llc Traitements combinés contre l'hépatite c

Also Published As

Publication number Publication date
US9119868B2 (en) 2015-09-01
AU2012296446B2 (en) 2015-07-09
PE20141391A1 (es) 2014-10-29
CN103929965A (zh) 2014-07-16
ES2735542T3 (es) 2019-12-19
CN106109479A (zh) 2016-11-16
EA201690327A1 (ru) 2016-06-30
JP2014524446A (ja) 2014-09-22
EA024357B1 (ru) 2016-09-30
CN103929965B (zh) 2016-08-17
BR112014003556A2 (pt) 2017-03-21
MX2014001833A (es) 2014-02-27
CO6880064A2 (es) 2014-02-28
JP6121419B2 (ja) 2017-04-26
DOP2014000030A (es) 2014-06-30
KR101975233B1 (ko) 2019-05-07
CA2843502A1 (fr) 2013-02-21
KR20180129973A (ko) 2018-12-05
JP2017165732A (ja) 2017-09-21
IL230484A (en) 2016-11-30
KR20140093209A (ko) 2014-07-25
WO2013025992A1 (fr) 2013-02-21
EA201490199A1 (ru) 2015-01-30
CL2014000394A1 (es) 2014-08-01
NZ619985A (en) 2016-06-24
EA201490199A8 (ru) 2015-12-30
IL230484A0 (en) 2014-03-31
US20140212384A1 (en) 2014-07-31
SG10201606646RA (en) 2016-09-29
ZA201502595B (en) 2017-01-25
CR20140075A (es) 2014-03-24
EP2744342A4 (fr) 2015-01-28
EP2744342B1 (fr) 2019-04-24
ZA201400435B (en) 2015-09-30
US20150320777A1 (en) 2015-11-12
US10238678B2 (en) 2019-03-26
CL2016000300A1 (es) 2016-09-02
CA2843502C (fr) 2019-01-15
AU2012296446A1 (en) 2014-02-13
EP2744342A1 (fr) 2014-06-25

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