CL2016000300A1 - Métodos terapéuticos - Google Patents
Métodos terapéuticosInfo
- Publication number
- CL2016000300A1 CL2016000300A1 CL2016000300A CL2016000300A CL2016000300A1 CL 2016000300 A1 CL2016000300 A1 CL 2016000300A1 CL 2016000300 A CL2016000300 A CL 2016000300A CL 2016000300 A CL2016000300 A CL 2016000300A CL 2016000300 A1 CL2016000300 A1 CL 2016000300A1
- Authority
- CL
- Chile
- Prior art keywords
- therapeutic methods
- therapeutic agent
- compound
- hepatitits
- hcv
- Prior art date
Links
- 238000002560 therapeutic procedure Methods 0.000 title 1
- 239000003814 drug Substances 0.000 abstract 2
- 229940124597 therapeutic agent Drugs 0.000 abstract 2
- -1 2-PHENYL-BENZOFURAN COMPOUND Chemical class 0.000 abstract 1
- 241000700605 Viruses Species 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/7056—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing five-membered rings with nitrogen as a ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
- A61K31/343—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/69—Boron compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/21—Interferons [IFN]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/21—Interferons [IFN]
- A61K38/212—IFN-alpha
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/21—Interferons [IFN]
- A61K38/215—IFN-beta
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Gastroenterology & Hepatology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- Virology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
USO DE UN COMPUESTO 2-FENIL-BENZOFURANO SUSTITUIDO Y UN SEGUNDO AGENTE TERAPEUTICO, PARA EL TRATAMIENTO DEL VIRUS DE LA HEPATITITS C (HCV); Y COMPOSICION QUE COMPRENDE A DICHO COMPUESTO Y AL SEGUNDO AGENTE TERAPEUTICO.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201161524429P | 2011-08-17 | 2011-08-17 | |
US201161526787P | 2011-08-24 | 2011-08-24 |
Publications (1)
Publication Number | Publication Date |
---|---|
CL2016000300A1 true CL2016000300A1 (es) | 2016-09-02 |
Family
ID=47715500
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CL2014000394A CL2014000394A1 (es) | 2011-08-17 | 2014-02-17 | Uso de compuestos fenil-benzofuran-sulfamido sustituidos para el tratamiento del virus de la hepatitis c (hcv); y composicion farmaceutica que comprende a estos compuestos fenil-benzofuran-sulfamido sustituidos. |
CL2016000300A CL2016000300A1 (es) | 2011-08-17 | 2016-02-05 | Métodos terapéuticos |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CL2014000394A CL2014000394A1 (es) | 2011-08-17 | 2014-02-17 | Uso de compuestos fenil-benzofuran-sulfamido sustituidos para el tratamiento del virus de la hepatitis c (hcv); y composicion farmaceutica que comprende a estos compuestos fenil-benzofuran-sulfamido sustituidos. |
Country Status (21)
Country | Link |
---|---|
US (2) | US9119868B2 (es) |
EP (1) | EP2744342B1 (es) |
JP (2) | JP6121419B2 (es) |
KR (2) | KR20140093209A (es) |
CN (2) | CN106109479A (es) |
AU (1) | AU2012296446B2 (es) |
BR (1) | BR112014003556A2 (es) |
CA (1) | CA2843502C (es) |
CL (2) | CL2014000394A1 (es) |
CO (1) | CO6880064A2 (es) |
CR (1) | CR20140075A (es) |
DO (1) | DOP2014000030A (es) |
EA (2) | EA201690327A1 (es) |
ES (1) | ES2735542T3 (es) |
IL (1) | IL230484A (es) |
MA (1) | MA35347B1 (es) |
MX (1) | MX2014001833A (es) |
PE (1) | PE20141391A1 (es) |
SG (1) | SG10201606646RA (es) |
WO (1) | WO2013025992A1 (es) |
ZA (2) | ZA201400435B (es) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2013025992A1 (en) * | 2011-08-17 | 2013-02-21 | Glaxosmithkline Llc | Therapeutic methods |
MX354676B (es) * | 2011-08-19 | 2018-03-15 | Glaxo Group Ltd | Compuestos de benzofurano para el tratamiento de infecciones por el virus de hepatitis c (hcv). |
KR20170081257A (ko) * | 2014-11-10 | 2017-07-11 | 글락소스미스클라인 인털렉츄얼 프로퍼티 (넘버 2) 리미티드 | C형 간염에 대한 조합 장기 작용 조성물 및 방법 |
PE20170921A1 (es) * | 2014-11-10 | 2017-07-12 | Glaxosmithkline Intellectual Property (No 2) Ltd | Composiciones farmaceuticas de accion prolongada para la hepatitis c |
CN105732602B (zh) * | 2015-09-23 | 2017-04-19 | 常州寅盛药业有限公司 | 作为ns4b抑制剂的苯并呋喃类似物 |
CN110799193B (zh) * | 2017-03-21 | 2023-12-12 | 斯克利普斯研究院 | 铜和镍催化的脱羧硼化反应 |
KR20220088736A (ko) * | 2019-10-25 | 2022-06-28 | 스미토모 파마 가부시키가이샤 | 신규 치환 축환형 화합물 |
Family Cites Families (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU5920400A (en) * | 1999-07-07 | 2001-01-22 | Du Pont Pharmaceuticals Company | Cell-based assay systems for examining hcv ns3 protease activity |
US7265152B2 (en) * | 2002-11-01 | 2007-09-04 | Viropharma Incorporated | Benzofuran compounds, compositions and methods for treatment and prophylaxis of hepatitis C viral infections and associated diseases |
WO2005051318A2 (en) | 2003-11-24 | 2005-06-09 | Viropharma Incorporated | Compounds, compositions and methods for treatment and prophylaxis of hepatitis c viral infections and associated diseases |
CA2651212A1 (en) * | 2006-05-02 | 2007-11-15 | Anacor Pharmaceuticals, Inc. | Hydrolytically-resistant boron-containing therapeutics and methods of use |
MX2010001650A (es) | 2007-08-10 | 2010-08-02 | Glaxosmithkline Llc | Entidades quimicas biciclicas que contienen nitrogeno para el tratamiento de infecciones virales. |
GB0719366D0 (en) * | 2007-10-03 | 2007-11-14 | Smithkline Beecham Corp | Compounds |
ES2377280T3 (es) * | 2008-02-14 | 2012-03-26 | F. Hoffmann-La Roche Ag | Compuestos heterocíclicos antivíricos |
WO2009137500A1 (en) | 2008-05-05 | 2009-11-12 | Wyeth | 6-substituted benzofuran compounds to treat infection with hepatitis c virus |
WO2011050284A1 (en) * | 2009-10-23 | 2011-04-28 | Glaxosmithkline Llc | Pyrazolylpyridine antiviral agents |
WO2011103063A1 (en) | 2010-02-19 | 2011-08-25 | Glaxo Group Limited | Therapeutic compounds |
WO2012067663A1 (en) | 2010-11-18 | 2012-05-24 | Glaxo Group Limited | Compounds |
WO2013025975A1 (en) * | 2011-08-17 | 2013-02-21 | Glaxosmithkline Llc | Combination treatments for hepatitis c |
WO2013025992A1 (en) * | 2011-08-17 | 2013-02-21 | Glaxosmithkline Llc | Therapeutic methods |
MX354676B (es) * | 2011-08-19 | 2018-03-15 | Glaxo Group Ltd | Compuestos de benzofurano para el tratamiento de infecciones por el virus de hepatitis c (hcv). |
CA2845321A1 (en) * | 2011-08-24 | 2013-02-28 | Glaxosmithkline Llc | Combination treatments for hepatitis c |
-
2012
- 2012-08-17 WO PCT/US2012/051349 patent/WO2013025992A1/en active Application Filing
- 2012-08-17 US US14/239,184 patent/US9119868B2/en not_active Expired - Fee Related
- 2012-08-17 KR KR1020147007080A patent/KR20140093209A/ko active Application Filing
- 2012-08-17 SG SG10201606646RA patent/SG10201606646RA/en unknown
- 2012-08-17 MX MX2014001833A patent/MX2014001833A/es unknown
- 2012-08-17 EA EA201690327A patent/EA201690327A1/ru unknown
- 2012-08-17 AU AU2012296446A patent/AU2012296446B2/en not_active Ceased
- 2012-08-17 EA EA201490199A patent/EA024357B1/ru not_active IP Right Cessation
- 2012-08-17 BR BR112014003556A patent/BR112014003556A2/pt not_active IP Right Cessation
- 2012-08-17 CN CN201610457657.XA patent/CN106109479A/zh active Pending
- 2012-08-17 KR KR1020187034213A patent/KR101975233B1/ko active IP Right Grant
- 2012-08-17 JP JP2014526244A patent/JP6121419B2/ja active Active
- 2012-08-17 ES ES12824599T patent/ES2735542T3/es active Active
- 2012-08-17 CN CN201280039778.2A patent/CN103929965B/zh not_active Expired - Fee Related
- 2012-08-17 PE PE2014000183A patent/PE20141391A1/es not_active Application Discontinuation
- 2012-08-17 CA CA2843502A patent/CA2843502C/en not_active Expired - Fee Related
- 2012-08-17 EP EP12824599.0A patent/EP2744342B1/en active Active
-
2014
- 2014-01-16 IL IL230484A patent/IL230484A/en active IP Right Grant
- 2014-01-20 ZA ZA2014/00435A patent/ZA201400435B/en unknown
- 2014-02-12 MA MA36751A patent/MA35347B1/fr unknown
- 2014-02-13 CO CO14031175A patent/CO6880064A2/es unknown
- 2014-02-17 CR CR20140075A patent/CR20140075A/es unknown
- 2014-02-17 DO DO2014000030A patent/DOP2014000030A/es unknown
- 2014-02-17 CL CL2014000394A patent/CL2014000394A1/es unknown
-
2015
- 2015-04-17 ZA ZA2015/02595A patent/ZA201502595B/en unknown
- 2015-07-20 US US14/803,478 patent/US10238678B2/en not_active Expired - Fee Related
-
2016
- 2016-02-05 CL CL2016000300A patent/CL2016000300A1/es unknown
-
2017
- 2017-03-29 JP JP2017064038A patent/JP2017165732A/ja active Pending
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