MA35269B1 - Nouveaux dérivés de phtalazinone-pyrrolopyrimidinecarboxamide - Google Patents

Nouveaux dérivés de phtalazinone-pyrrolopyrimidinecarboxamide

Info

Publication number
MA35269B1
MA35269B1 MA36689A MA36689A MA35269B1 MA 35269 B1 MA35269 B1 MA 35269B1 MA 36689 A MA36689 A MA 36689A MA 36689 A MA36689 A MA 36689A MA 35269 B1 MA35269 B1 MA 35269B1
Authority
MA
Morocco
Prior art keywords
pyrrolopyrimidinecarboxamide
phthalazinone
derivatives
compounds
type
Prior art date
Application number
MA36689A
Other languages
English (en)
French (fr)
Inventor
Thomas Stengel
Thomas Maier
Alexander Mann
Josef Stadlwieser
Dieter Flockerzi
Andreas Pahl
Ewald Benediktus
Manuela Hessmann
Tobias Kanacher
Ragna Hussong
Christof Zitt
Hans Christof Holst
Rolf-Peter Hummel
Martin Viertelhaus
Hermann Tenor
Torsten Dunkern
Armin Hatzelmann
Christian Hesslinger
Original Assignee
Akeda Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=44764312&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MA35269(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Akeda Gmbh filed Critical Akeda Gmbh
Publication of MA35269B1 publication Critical patent/MA35269B1/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
MA36689A 2011-06-17 2014-01-16 Nouveaux dérivés de phtalazinone-pyrrolopyrimidinecarboxamide MA35269B1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP11170440 2011-06-17
PCT/EP2012/061084 WO2012171900A1 (en) 2011-06-17 2012-06-12 Novel phthalazinone-pyrrolopyrimidinecarboxamide derivatives

Publications (1)

Publication Number Publication Date
MA35269B1 true MA35269B1 (fr) 2014-07-03

Family

ID=44764312

Family Applications (1)

Application Number Title Priority Date Filing Date
MA36689A MA35269B1 (fr) 2011-06-17 2014-01-16 Nouveaux dérivés de phtalazinone-pyrrolopyrimidinecarboxamide

Country Status (22)

Country Link
US (2) US20140112945A1 (enExample)
EP (1) EP2721030B1 (enExample)
JP (1) JP5980318B2 (enExample)
KR (1) KR20140037195A (enExample)
CN (1) CN103582644B (enExample)
AR (1) AR086915A1 (enExample)
AU (1) AU2012269133A1 (enExample)
BR (1) BR112013031791A2 (enExample)
CA (1) CA2837248A1 (enExample)
CL (1) CL2013003556A1 (enExample)
CO (1) CO6852074A2 (enExample)
CR (1) CR20130656A (enExample)
DO (1) DOP2013000298A (enExample)
EA (1) EA023713B1 (enExample)
EC (1) ECSP13013076A (enExample)
ES (1) ES2564882T3 (enExample)
MA (1) MA35269B1 (enExample)
MX (1) MX2013014888A (enExample)
PE (1) PE20140648A1 (enExample)
PH (1) PH12013502546A1 (enExample)
TN (1) TN2013000439A1 (enExample)
WO (1) WO2012171900A1 (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20170133497A (ko) 2015-04-09 2017-12-05 갈데르마 소시에떼아노님 인디고 내추럴리스로부터의 추출물 및 그의 제조 방법
TWI737602B (zh) 2015-04-09 2021-09-01 瑞士商高德美公司 藥學組合物及其製劑
JP2018510891A (ja) 2015-04-09 2018-04-19 ガルデルマ・ソシエテ・アノニム 抗菌性インジゴナチュラリス又はインジゴ産生植物抽出物及びその使用
JP6803849B2 (ja) * 2015-04-09 2020-12-23 ガルデルマ・ソシエテ・アノニム インジゴナチュラリス又はインジゴ産生植物の抽出物を用いたアトピー性皮膚炎の処置
US12383547B2 (en) 2020-07-01 2025-08-12 Vanderbilt University Methods of treatment for a kidney disease

Family Cites Families (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8828477D0 (en) 1988-12-06 1989-01-05 Riker Laboratories Inc Medical aerosol formulations
DE407028T1 (de) 1989-05-31 1994-03-17 Fisons Plc Medikament und Inhalationsvorrichtung dafür.
GB8921222D0 (en) 1989-09-20 1989-11-08 Riker Laboratories Inc Medicinal aerosol formulations
IL97065A (en) 1990-02-02 1994-01-25 Fisons Plc Repellent preparations for aerosol
DE4003272A1 (de) 1990-02-03 1991-08-08 Boehringer Ingelheim Kg Neue treibgasmischungen und ihre verwendung in arzneimittelzubereitungen
JPH05505824A (ja) 1990-03-23 1993-08-26 ミネソタ　マイニング　アンド　マニュファクチャリング　カンパニー 所定投与量エアロゾル製剤の製造のための可溶性弗素界面活性剤の使用
ATE114112T1 (de) 1990-10-18 1994-12-15 Minnesota Mining & Mfg Aerosolzubereitung, die beclometason 17,21- dipropionat enthält.
AU650953B2 (en) 1991-03-21 1994-07-07 Novartis Ag Inhaler
IL104068A (en) 1991-12-12 1998-10-30 Glaxo Group Ltd Surfactant-free pharmaceutical aerosol formulation comprising 1,1,1,2-tetrafluoroethane or 1,1,1,2,3,3,3-heptafluoro-n- propane as propellant
GB9213874D0 (en) 1992-06-30 1992-08-12 Fisons Plc Process to novel medicament form
GB9306703D0 (en) 1993-03-31 1993-05-26 Fisons Plc Inhalation device
IL111194A (en) 1993-10-08 1998-02-08 Fisons Plc Process for the production of medicament formulations
SK283270B6 (sk) * 1997-01-15 2003-04-01 Altana Pharma Ag Ftalazinóny, farmaceutické prostriedky s ich obsahom a ich použitie
SI1070056T1 (en) * 1998-03-14 2004-12-31 Altana Pharma Ag Phthalazinone pde iii/iv inhibitors
ATE234604T1 (de) 1998-08-04 2003-04-15 Jago Res Ag Medizinische aerosolformulierungen
US6397838B1 (en) 1998-12-23 2002-06-04 Battelle Pulmonary Therapeutics, Inc. Pulmonary aerosol delivery device and method
DE60030103T2 (de) 1999-04-23 2007-02-08 Ventaira Pharmaceuticals, Inc., Columbus Elektrostatisches versprühen mit transfer- hoher masse
EP1194244B1 (en) 1999-04-23 2005-12-21 Battelle Memorial Institute Directionally controlled ehd aerosol sprayer
CN1471515A (zh) * 2000-06-05 2004-01-28 ��̹��ҽҩ��˾ 作为β2-肾上腺素受体激动剂及PDE-4抑制剂的有效的化合物
CN1635870A (zh) 2000-10-09 2005-07-06 3M创新有限公司 药用气雾剂制剂
NZ527424A (en) 2001-02-15 2005-02-25 Altana Pharma Ag Phthalayinone-piperidino-derivatives as PDE4 inhibitors
EP1385848A2 (en) 2001-04-25 2004-02-04 ALTANA Pharma AG Phtalazinones derivatives useful as pde4/7 inhibitors
US20060167001A1 (en) * 2002-08-10 2006-07-27 Sterk Jan G Pyridazinone-derivatives as pde4 inhibitors
WO2004018449A1 (en) 2002-08-10 2004-03-04 Altana Pharma Ag Piperidine-derivatives as pde4 inhibitors
HRP20050198A2 (hr) 2002-08-10 2006-04-30 Altana Pharma Ag Piperidin-piridazoni i ftalazoni kao inhibitori pde4
PL378247A1 (pl) * 2003-01-14 2006-03-20 Altana Pharma Ag Inhibitory PDE4 w terapii nowotworów komórek limfoidalnych
EP1716133B1 (en) 2004-02-04 2008-03-26 Nycomed GmbH 2-(piperidin-4-yl)-4,5-dihydro-2h-pyridazin-3-one derivatives as pde4 inhibitors
EP1720854A1 (en) 2004-02-04 2006-11-15 Altana Pharma AG Phthalzinone derivatives as pde4 inhibitors
AR070454A1 (es) 2008-02-27 2010-04-07 Nycomed Gmbh Pirrolopirimidincarboxamidas y composiciones farmaceuticas que las comprenden
AR077898A1 (es) * 2009-08-26 2011-09-28 Nycomed Gmbh Metilpirrolopirimidincarboxamidas

Also Published As

Publication number Publication date
US20140112945A1 (en) 2014-04-24
CO6852074A2 (es) 2014-01-30
EA201400001A1 (ru) 2014-05-30
PH12013502546A1 (en) 2014-01-27
CL2013003556A1 (es) 2014-06-13
EP2721030A1 (en) 2014-04-23
PE20140648A1 (es) 2014-05-30
AR086915A1 (es) 2014-01-29
JP2014517021A (ja) 2014-07-17
WO2012171900A1 (en) 2012-12-20
ES2564882T3 (es) 2016-03-29
MX2013014888A (es) 2014-02-27
US20160108049A1 (en) 2016-04-21
CN103582644A (zh) 2014-02-12
ECSP13013076A (es) 2014-01-31
EA023713B1 (ru) 2016-07-29
KR20140037195A (ko) 2014-03-26
CN103582644B (zh) 2016-07-20
AU2012269133A1 (en) 2014-01-30
BR112013031791A2 (pt) 2017-01-31
DOP2013000298A (es) 2014-03-31
JP5980318B2 (ja) 2016-08-31
TN2013000439A1 (en) 2015-03-30
EP2721030B1 (en) 2015-12-16
CR20130656A (es) 2014-02-18
CA2837248A1 (en) 2012-12-20

Similar Documents

Publication Publication Date Title
UY36907A (es) Nuevas carboxamidas de acción microbiocida
EA201000113A1 (ru) Пиразольные соединения
EA201100447A1 (ru) Органические соединения
EA201070186A1 (ru) Способы и соединения, предназначенные для получения ингибиторов котранспортера натрий-глюкозы 2 типа
EA201200018A1 (ru) Триазольные соединения, несущие серосодержащий заместитель
CU24039B1 (es) Derivados de imidazolidin-2-ona 1,3-disustituida como inhibidores de cyp17
MA37142A3 (fr) Dérivés de dihydro-benzo-oxazine et de dihydro-pyrido-oxazine
ME03065B (me) 1,2,5-oksadiazoli kao inhibitori indolamin 2,3-dioksigenaze
CR9830A (es) Compuestos de amino-5-[4-(difluorometoxi)fenil]-5-fenilimidazolona para la inhibicion de la b-secretasa
MA34284B1 (fr) Indoles
MA35245B1 (fr) Pyridin-2-amides utiles comme agonistes de cb2
UA108219C2 (uk) Протипаразитарні дигідроазолові сполуки та композиція, яка їх містить (варіанти)
EA200970913A1 (ru) 2-пиридинкарбоксамидные производные в качестве модуляторов натриевых каналов
CR20140135A (es) Nuevos derivados de aril-quinolina
MA35086B1 (fr) Compose de triazolopyridine
MA38645A1 (fr) Nouveaux inhibiteurs de cyp17/antiandrogènes
EA201000550A1 (ru) Производные тиазола
EA201170997A1 (ru) Производные индола в качестве противораковых агентов
MA31229B1 (fr) Composés de 6-benzyl-2, 3,4, 7-tétrahydro-indolo [2, 3-c] quinoline utiles en tant qu'inhibiteurs de pde5
SV2011003902A (es) 1-(arilsulfonil)-4-(piperazin-1-il)-1h-benzimidazoles como ligandos de 5- hidroxitriptamina-6
CR20110387A (es) Microbiocidas nuevos
ECSP10010425A (es) Pirrolopirimidincarboxamidas
EA201070599A1 (ru) Ингибиторы равновесного переносчика нуклеозидов ent1
EA201070010A1 (ru) Производные 7-алкинил-1,8-нафтиридонов, их получение и их применение в терапии
EA200901504A1 (ru) Производные пиразолона, как ингибиторы pde4